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Volumn 6, Issue 3, 2009, Pages 171-180

The pro-apoptotic substance thapsigargin selectively stimulates re-growth of brain capillaries

Author keywords

Angiogenesis; In vitro model; Neuronal cell death; Vascularization

Indexed keywords

GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; LAMININ; NERVE GROWTH FACTOR; THAPSIGARGIN;

EID: 68549128734     PISSN: 15672026     EISSN: None     Source Type: Journal    
DOI: 10.2174/156720209788970063     Document Type: Article
Times cited : (8)

References (78)
  • 1
    • 0036581222 scopus 로고    scopus 로고
    • The GDNF family: Signalling, biological functions and therapeutic value
    • Airaksinen, MS, Saarma, M. (2002) The GDNF family: signalling, biological functions and therapeutic value. Neuroscience 3: 383-394.
    • (2002) Neuroscience , vol.3 , pp. 383-394
    • Airaksinen, M.S.1    Saarma, M.2
  • 2
    • 0029584686 scopus 로고
    • GDNF prevents degeneration and promotes the phenotype of brain noradrenergic neurons in vivo
    • DOI 10.1016/0896-6273(95)90024-1
    • Arenas, E, Trupp, M, Akerud, P, Ibanez, CF. (1995) GDNF prevents degeneration and promotes the phenotype of brain noradrenergic neurons in vivo. Neuron 15: 1465-1473. (Pubitemid 26005383)
    • (1995) Neuron , vol.15 , Issue.6 , pp. 1465-1473
    • Arenas, E.1    Trupp, M.2    Akerud, P.3    Ibanez, C.F.4
  • 5
    • 0027444263 scopus 로고
    • Structural modifications associated with synaptic development in area CA1 of rat hippocampal organotypic cultures
    • DOI 10.1016/0165-3806(93)90108-M
    • Buchs, PA, Stoppini, L, Muller, D. (1993) Structural modifications associated with synaptic development in area CA1 of rat hippocampal organotypic cultures. Brain Res Dev 71: 81-91. (Pubitemid 23034296)
    • (1993) Developmental Brain Research , vol.71 , Issue.1 , pp. 81-91
    • Buchs, P.-A.1    Stoppini, L.2    Muller, D.3
  • 6
    • 0035852680 scopus 로고    scopus 로고
    • Nontropic actions of neurotrophins: Subcortical nerve growth factor gene delivery reverses age-related degeneration of primate cortical cholinergic innervation
    • DOI 10.1073/pnas.98.4.1941
    • Connor, JM, Darracq, MA, Roberts, J, Tuszynski, MH. (2001) Nontropic actions of neurotrophins: subcortical nerve growth factor gene delivery reverses age-related degeneration of primate cortical cholinergic innervation. Proc Natl Acad Sci USA 98: 1941-1946. (Pubitemid 32165602)
    • (2001) Proceedings of the National Academy of Sciences of the United States of America , vol.98 , Issue.4 , pp. 1941-1946
    • Conner, J.M.1    Darracq, M.A.2    Roberts, J.3    Tuszynski, M.H.4
  • 7
    • 0019958980 scopus 로고
    • Development of cross-tolerance to 5-hydroxytryptamine in organotypic cultures of mouse spinal cord-ganglia during chronic exposure to morphine
    • Crain, SM, Crain, B, Peterson, ER. (1982) Development of cross-tolerance to 5-hydroxytryptamine in organotypic cultures of mouse spinal cord-ganglia during chronic exposure to morphine. Life Sci 31: 241-247.
    • (1982) Life Sci , vol.31 , pp. 241-247
    • Crain, S.M.1    Crain, B.2    Peterson, E.R.3
  • 8
    • 20344392461 scopus 로고    scopus 로고
    • Caspases-2, -3, and -7 are involved in thapsigargin-induced apoptosis of SH-SY5Y neuroblastoma cells
    • DOI 10.1002/jnr.20471
    • Dahmer, MK. (2005) Caspases-2,-3, and -7 are involved in thapsigargin-induced apoptosis of SH-SY5Y neuroblastoma cells. J Neurosci Res 80:576-583. (Pubitemid 40780817)
    • (2005) Journal of Neuroscience Research , vol.80 , Issue.4 , pp. 576-583
    • Dahmer, M.K.1
  • 9
    • 0141741347 scopus 로고    scopus 로고
    • Parkinson's disease: Mechanisms and models
    • Dauer, W, Przedborski, S. (2003) Parkinson's disease: mechanisms and models. Neuron 39: 889-909.
    • (2003) Neuron , vol.39 , pp. 889-909
    • Dauer, W.1    Przedborski, S.2
  • 10
    • 0011162190 scopus 로고
    • Selective loss of central cholinergic neurons in Alzheimer's disease
    • Davies, P, Maloney, AJF. (1976) Selective loss of central cholinergic neurons in Alzheimer's disease. Lancet 2: 1403. (Pubitemid 8004505)
    • (1976) Lancet , vol.2 , Issue.8000 , pp. 1403
    • Davies, P.1    Maloney, A.J.F.2
  • 11
    • 38049155818 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis
    • Deniaud, A, Sharaf el dein, O, Maillier, E, Poncet, D, Kroemer, G, Lemaire, C, Brenner, C. (2008) Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis. Oncogene 27: 285-299.
    • (2008) Oncogene , vol.27 , pp. 285-299
    • Deniaud, A.1    Sharaf El Dein, O.2    Maillier, E.3    Poncet, D.4    Kroemer, G.5    Lemaire, C.6    Brenner, C.7
  • 12
    • 1342321750 scopus 로고    scopus 로고
    • PI 3-kinase, Akt and cell survival
    • Downward, J. (2004) PI 3-kinase, Akt and cell survival. Sem Cell Dev Biol 15: 177-182.
    • (2004) Sem Cell Dev Biol , vol.15 , pp. 177-182
    • Downward, J.1
  • 13
    • 0023039236 scopus 로고
    • Laminin immunohistochemistry: A simple method to visualize and quantitate vascular structures in the mammalian brain
    • DOI 10.1016/0165-0270(86)90128-7
    • Eriksdotter-Nilsson, M, Björklund, H, Olson, L. (1986) Laminin immunohistochemistry: a simple method to visualize and quantitate vascular structures in the mammalian brain. J Neurosci Methods 17: 275-286. (Pubitemid 17168151)
    • (1986) Journal of Neuroscience Methods , vol.17 , Issue.4 , pp. 275-286
    • Eriksdotter-Nilsson, M.1    Bjorklund, H.2    Olson, L.3
  • 15
    • 0035736259 scopus 로고    scopus 로고
    • Organelle-specific initiation of cell death pathways
    • Ferri, KF, Kroemer, G. (2001) Organelle-specific initiation of cell death pathways. Nature Cell Biol 3: 255-263.
    • (2001) Nature Cell Biol , vol.3 , pp. 255-263
    • Ferri, K.F.1    Kroemer, G.2
  • 16
    • 0037375843 scopus 로고    scopus 로고
    • Dopaminergic neurons develop axonal projections to their target areas in organotypic co-cultures of the ventral mesencephalon and the striatum/prefrontal cortex
    • DOI 10.1016/S0197-0186(02)00134-1, PII S0197018602001341
    • Franke, H, Schelhorn, N, Illes, P. (2003) Dopaminergic neurons develop axonal projections to their target areas in organotypic co-cultures of the ventral mesencephalon and the striatum/prefrontal cortex. Neurochem Int 42: 431-439. (Pubitemid 36044676)
    • (2003) Neurochemistry International , vol.42 , Issue.5 , pp. 431-439
    • Franke, H.1    Schelhorn, N.2    Illes, P.3
  • 18
    • 0021346474 scopus 로고
    • Guidance of acetylcholinesterase-containing fibers by target tissue in co-cultured brain slices
    • Gähwiler, BH, Hefti, F. (1984) Guidance of acetylcholinesterase- containing fibers by target tissue in co-cultured brain slices. Neuroscience 40: 235-243.
    • (1984) Neuroscience , vol.40 , pp. 235-243
    • Gähwiler, B.H.1    Hefti, F.2
  • 19
    • 0025353344 scopus 로고
    • Continuous presence of nerve growth factor is required for maintenance of cholinergic septal neurons in organotypic slice cultures
    • DOI 10.1016/0306-4522(90)90348-8
    • Gähwiler, BH, Tietschin, L, Knöpfel, T, Enz, A. (1990) Continuous presence of nerve growth factor is required for maintenance of cholinergic septal neurons in organotypic slice cultures. Neuroscience 36: 27-31. (Pubitemid 20221712)
    • (1990) Neuroscience , vol.36 , Issue.1 , pp. 27-31
    • Gahwiler, B.H.1    Rietschin, L.2    Knopfel, T.3    Enz, A.4
  • 21
    • 0031457545 scopus 로고    scopus 로고
    • Short-term exposure to thapsigargin inhibits neointima formation in human saphenous vein
    • George, SJ, Johnson, JL, Angelini, GD, Jeremy, JY. (1997) Short-term exposure to thapsigargin inhibits neointima formation in human saphenous vein. Arterioscler. Thromb Vasc Biol 17: 2500-2506.
    • (1997) Arterioscler. Thromb Vasc Biol , vol.17 , pp. 2500-2506
    • George, S.J.1    Johnson, J.L.2    Angelini, G.D.3    Jeremy, J.Y.4
  • 22
    • 34250725402 scopus 로고    scopus 로고
    • 2+ as a key regulator of cell life and death
    • DOI 10.1038/sj.cdd.4402147, PII 4402147
    • Giacomello, M, Drago, I, Pizzo, P, Pozzan T. (2007) Mitochondrial Ca 2+ as a key regulator of cell life and death. Cell Death Differ 14:1267-1274. (Pubitemid 46965258)
    • (2007) Cell Death and Differentiation , vol.14 , Issue.7 , pp. 1267-1274
    • Giacomello, M.1    Drago, I.2    Pizzo, P.3    Pozzan, T.4
  • 24
    • 0025486143 scopus 로고
    • Nerve growth factor infusion into the denervated adult rat hippocampal formation promotes its cholinergic reinnervation
    • Hagg, T, Vahlsing, HL, Mathorpe, M, Varon, S. (1990) Nerve growth factor infusion into the denervated adult rat hippocampal formation promotes its cholinergic reinnervation. J Neurosci 10: 3087-3092.
    • (1990) J Neurosci , vol.10 , pp. 3087-3092
    • Hagg, T.1    Vahlsing, H.L.2    Mathorpe, M.3    Varon, S.4
  • 25
    • 0021955153 scopus 로고
    • Nerve growth factor increases choline acetyltransferase but not survival or fiber outgrowth of cultured fetal septal cholinergic neurons
    • DOI 10.1016/0306-4522(85)90163-0
    • Hefti, F, Hartikka, J, Eckstein, F, Gnahn, H, Heumann, R, Schwab, M. (1985) Nerve growth factor increases choline acetyltransferase but not survival or fiber outgrowth of cultured fetal septal cholinergic neurons. Neuroscience 14: 55-68. (Pubitemid 15124283)
    • (1985) Neuroscience , vol.14 , Issue.1 , pp. 55-68
    • Hefti, F.1    Hartikka, J.2    Eckenstein, F.3
  • 27
    • 0033963108 scopus 로고    scopus 로고
    • Apoptosis and neurologic disease
    • Honig, LS, Rosenberg, RN. (2000) Apoptosis and neurologic disease. Am J Med 108: 317-330.
    • (2000) Am J Med , vol.108 , pp. 317-330
    • Honig, L.S.1    Rosenberg, R.N.2
  • 28
    • 0028954078 scopus 로고
    • Mesencephalic grafts increase preprotachykinin-A mRNA expression in striatal grafts in an in oculo co-graft model
    • Humpel, C, Johansson, M, Marksteiner, J, Saria, A, Strömberg, I. (1995) Mesencephalic grafts increase preprotachykinin-A mRNA expression in striatal grafts in an in oculo co-graft model. Regul Peptides 56: 9-17.
    • (1995) Regul Peptides , vol.56 , pp. 9-17
    • Humpel, C.1    Johansson, M.2    Marksteiner, J.3    Saria, A.4    Strömberg, I.5
  • 29
    • 0036044105 scopus 로고    scopus 로고
    • Nerve growth factor and cholinergic CNS neurons studied in organotypic brain slices
    • Humpel, C, Weis, C. (2002) Nerve growth factor and cholinergic CNS neurons studied in organotypic brain slices. J Neural Transm 62: 253-263.
    • (2002) J Neural Transm , vol.62 , pp. 253-263
    • Humpel, C.1    Weis, C.2
  • 30
    • 0037378026 scopus 로고    scopus 로고
    • Oxidative stress in Parkinson's disease
    • Jenner, P. (2003) Oxidative stress in Parkinson's disease. Ann Neurol 53: 26-38.
    • (2003) Ann Neurol , vol.53 , pp. 26-38
    • Jenner, P.1
  • 31
    • 0033772970 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) and its effect on angiogenesis
    • Josko, J, Gwozdz, B, Jedrzejowsko-Szypulka, H, Hendryk, S. (2000) Vascular endothelial growth factor (VEGF) and its effect on angiogenesis. Med Sci Monit 6: 1047-1052. (Pubitemid 30824044)
    • (2000) Medical Science Monitor , vol.6 , Issue.5 , pp. 1047-1052
    • Josko, J.1    Gwozdz, B.2    Jedrzejowska-Szypulka, H.3    Hendryk, S.4
  • 32
    • 0029670459 scopus 로고    scopus 로고
    • Laminin α2 is a component of brain capillary basement membrane: Reduced expression in dystrophic dy mice
    • DOI 10.1016/0306-4522(95)00496-3
    • Jucker, M, Tian, M, Norton, DD, Sherman, C, Kusiak, JW. (1996) Laminin α2 is a component of brain capillary basement membrane: reduced expression in dystrophic dy mice. Neuroscience 71: 1153-1161. (Pubitemid 126335081)
    • (1996) Neuroscience , vol.71 , Issue.4 , pp. 1153-1161
    • Jucker, M.1    Tian, M.2    Norton, D.D.3    Sherman, C.4    Kusiak, J.W.5
  • 34
    • 0021061216 scopus 로고
    • Choline acetyltransferase in organotypic cultures of rat septum and hippocampus
    • DOI 10.1016/0304-3940(83)90274-4
    • Keller, F, Rimvall, K, Waser, PG. (1983) Choline acetyltransferase in organotypic cultures of rat septum and hippocampus. Neurosci Lett 42: 273-278. (Pubitemid 14223126)
    • (1983) Neuroscience Letters , vol.42 , Issue.3 , pp. 273-278
    • Keller, F.1    Rimvall, K.2    Waser, P.G.3
  • 35
    • 0029655656 scopus 로고    scopus 로고
    • Nerve growth factor withdrawal induces the apoptotic death of developing septal cholinergic neurons in vitro: Protection by cyclic AMP analogue and high potassium
    • Kew, JNC, Smith, DW, Sofroniew, MV. (1996) Nerve growth factor withdrawal induces the apoptotic death of developing septal cholinergic neurons in vitro: protection by cyclic AMP analogue and high potassium. Neuroscience 70: 329-339. (Pubitemid 126755247)
    • (1996) Neuroscience , vol.70 , Issue.2 , pp. 329-339
    • Kew, J.N.C.1    Smith, D.W.2    Sofroniew, M.V.3
  • 37
    • 0024504607 scopus 로고
    • Stimulation of the nucleus basalis of Meynert increases acetylcholine release in the cerebral cortex in rats
    • DOI 10.1016/0304-3940(89)90371-6
    • Kurosawa, M, Sato, A, Sato, Y. (1989) Stimulation of the nucleus basalis of Meynert increases acetylcholine release in the cerebral cortex in rats. Neurosci Lett 98: 45-50. (Pubitemid 19054316)
    • (1989) Neuroscience Letters , vol.98 , Issue.1 , pp. 45-50
    • Kurosawa, M.1    Sato, A.2    Sato, Y.3
  • 38
    • 0035254648 scopus 로고    scopus 로고
    • Angiogenesis: Regulators and clinical applications
    • Liekens, S, de Clercq, E, Neyts, J. (2001) Angiogenesis: regulators and clinical applications. Biochem Pharmacol 61: 253-270.
    • (2001) Biochem Pharmacol , vol.61 , pp. 253-270
    • Liekens, S.1    De Clercq, E.2    Neyts, J.3
  • 39
  • 40
    • 0036889192 scopus 로고    scopus 로고
    • 17β-estradiol and the phytoestrogen genistein attenuate neuronal apoptosis induced by the endoplasmic reticulum calcium-ATPase inhibitor thapsigargin
    • Linford, NJ, Dorsa, DM. (2002) 17β-estradiol and the phytoestrogen genistein attenuate neuronal apoptosis induced by the endoplasmic reticulum calcium-ATPase inhibitor thapsigargin. Steroids 76: 1029-1040.
    • (2002) Steroids , vol.76 , pp. 1029-1040
    • Linford, N.J.1    Dorsa, D.M.2
  • 41
    • 0030915855 scopus 로고    scopus 로고
    • Oxidative stress hypothesis in Alzheimer's disease
    • DOI 10.1016/S0891-5849(96)00629-6, PII S0891584996006296
    • Markesbery, WR. (1997) Oxidative stress hypothesis in Alzheimer's disease. Free Radic Biol Med 23: 134-147. (Pubitemid 27217017)
    • (1997) Free Radical Biology and Medicine , vol.23 , Issue.1 , pp. 134-147
    • Markesbery, W.R.1
  • 42
    • 0029811226 scopus 로고    scopus 로고
    • Deficient glutamate transport is associated with neurodegeneration in Alzheimer's disease
    • Masliah, E, Alford, M, DeTeresa, R, Mallory, M, Hansen, L. (1996) Deficient glutamate transport is associated with neurodegeneration in Alzheimer's disease. Ann Neurol 40: 759-766. (Pubitemid 26415188)
    • (1996) Annals of Neurology , vol.40 , Issue.5 , pp. 759-766
    • Masliah, E.1    Alford, M.2    Deteresa, R.3    Mallory, M.4    Hansen, L.5
  • 43
    • 0034329742 scopus 로고    scopus 로고
    • Apoptosis in neurodegenerative disorders
    • Mattson, MP. (2000) Apoptosis in neurodegenerative disorders. Nat. Rev Mol Cell Biol 1: 120-129.
    • (2000) Nat. Rev Mol Cell Biol , vol.1 , pp. 120-129
    • Mattson, M.P.1
  • 44
    • 2942557118 scopus 로고    scopus 로고
    • Expression of the pro-angiogenic factors vascular endothelial growth fator and interleukin-8/CXCL8 by human breast carcinomas is responsive to nutrient deprivation and endoplasmic reticulum stress
    • Marjon, PL, Bobrovnikova-Marjon, EV, Abcouwer, SF. (2004) Expression of the pro-angiogenic factors vascular endothelial growth fator and interleukin-8/CXCL8 by human breast carcinomas is responsive to nutrient deprivation and endoplasmic reticulum stress. Mol Cancer 3: 4.
    • (2004) Mol Cancer , vol.3 , pp. 4
    • Marjon, P.L.1    Bobrovnikova-Marjon, E.V.2    Abcouwer, S.F.3
  • 45
    • 0042668388 scopus 로고    scopus 로고
    • Brain capillaries and cholinergic neurons persist in organotypic brain slices in the absence of blood flow
    • Moser, KV, Schmidt-Kastner, R, Hinterhuber, H, Humpel. (2003) Brain capillaries and cholinergic neurons persist in organotypic brain slices in the absence of blood flow. Eur J Neurosci 18: 85-94.
    • (2003) Eur J Neurosci , vol.18 , pp. 85-94
    • Moser, K.V.1    Schmidt-Kastner, R.2    Hinterhuber, H.3    Humpel4
  • 46
    • 3142743792 scopus 로고    scopus 로고
    • Brain capillary endothelial cells proliferate in response to NGF, express NGF receptors and secrete NGF after inflammation
    • DOI 10.1016/j.brainres.2004.05.013, PII S0006899304007401
    • Moser, KV, Reindl, M, Blasig, I, Humpel, C. (2004) Brain capillary endothelial cells proliferate in response to NGF, express NGF receptors and secrete NGF after inflammation. Brain Res 1017: 53-60. (Pubitemid 38917143)
    • (2004) Brain Research , vol.1017 , Issue.1-2 , pp. 53-60
    • Moser, K.V.1    Reindl, M.2    Blasig, I.3    Humpel, C.4
  • 47
    • 0029161781 scopus 로고
    • Glial cytokines in Alzheimer's disease: Review and pathogenic implications
    • Mrak, RE, Sheng, JG, Griffin, WST. (1995) Glial cytokines in Alzheimer's disease: review and pathogenic implications. Hum Pathol 26: 816-823.
    • (1995) Hum Pathol , vol.26 , pp. 816-823
    • Mrak, R.E.1    Sheng, J.G.2    Griffin, W.S.T.3
  • 48
    • 0032936755 scopus 로고    scopus 로고
    • Etiology and pathogenesis of Parkinson's disease
    • Olanow, CW, Tatton, WG. (1999) Etiology and pathogenesis of Parkinson's disease. Ann Rev Neurosci 22: 123-144.
    • (1999) Ann Rev Neurosci , vol.22 , pp. 123-144
    • Olanow, C.W.1    Tatton, W.G.2
  • 49
    • 0025220949 scopus 로고
    • Rat ventral mesencephalon grown as organotypic slice cultures and co-cultured, hippocampus, and cerebellum
    • Ostergaard, K, Schou, JP, Zimmer, J. (1990) Rat ventral mesencephalon grown as organotypic slice cultures and co-cultured, hippocampus, and cerebellum. Exp Brain Res 82: 547-565.
    • (1990) Exp Brain Res , vol.82 , pp. 547-565
    • Ostergaard, K.1    Schou, J.P.2    Zimmer, J.3
  • 50
    • 0027464906 scopus 로고
    • Organotypic slice cultures of rat striatum, I. a histochemical and immunohistochemical study of acetylcholinesterase, choline acetyltransferase, glutamate decarboxylase and GABA
    • Ostergaard, K. (1993) Organotypic slice cultures of rat striatum, I. A histochemical and immunohistochemical study of acetylcholinesterase, choline acetyltransferase, glutamate decarboxylase and GABA. Neuroscience 53: 679-693.
    • (1993) Neuroscience , vol.53 , pp. 679-693
    • Ostergaard, K.1
  • 51
    • 27144557493 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress accelerates p53 degradation by the cooperative actions of Hdm2 and glycogen synthase kinase 3β
    • DOI 10.1128/MCB.25.21.9392-9405.2005
    • Pluquet, O, Qu, LK, Baltzis, D, Koromilas, AE. (2005) Endoplasmic reticulum stress accelerates p53 degradation by the cooperative actions of Hdm2 and glycogen synthase kinase 3beta. Mol Cell Biol 25: 9392-9405. (Pubitemid 41507840)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.21 , pp. 9392-9405
    • Pluquet, O.1    Qu, L.-K.2    Baltzis, D.3    Koromilas, A.E.4
  • 52
    • 0030795713 scopus 로고    scopus 로고
    • Specificity of attachment and neurite outgrowth of dissociated basal forebrain cholinergic neurons seeded on to organotypic slice cultures of forebrain
    • DOI 10.1016/S0306-4522(97)00067-5, PII S0306452297000675
    • Robertson, RT, Baratta, J, Kageyama, GH, Ha, DA, Yu, J. (1997) Specificity of attachment and neurite outgrowth of dissociated basal forebrain cholinergic neurons seeded on to organotypic slice cultures of forebrain. Neuroscience 80: 741-752. (Pubitemid 27334618)
    • (1997) Neuroscience , vol.80 , Issue.3 , pp. 741-752
    • Robertson, R.T.1    Baratta, J.2    Kageyama, G.H.3    Ha, D.H.4    Yu, J.5
  • 53
    • 0032774688 scopus 로고    scopus 로고
    • Dopamine neurons in a simple GDNF-treated meso-striatal organotypic co-culture model
    • DOI 10.1007/s002210050796
    • Schatz, DS, Kaufmann, WA, Saria, A, Humpel C. (1999) Dopamine neurons in a simple GDNF-treated meso-striatal organotypic coculture model. Exp Brain Res 127: 270-278. (Pubitemid 29349032)
    • (1999) Experimental Brain Research , vol.127 , Issue.3 , pp. 270-278
    • Schatz, D.S.1    Kaufmann, W.A.2    Saria, A.3    Humpel, C.4
  • 54
    • 0034050461 scopus 로고    scopus 로고
    • 3,4-methylenedioxymetamphetamine (ecstasy) induces c-fos-like protein and mRNA in rat organotypic dorsal striatal slices
    • DOI 10.1002/(SICI)1098-2396(200004)36:1<75::AID-SYN8>3.0.CO;2-I
    • Schatz, DS, Kaufmann, WA, Schuligoi, R, Humpel, C, Saria, A. (2000) 3,4-methylen-edioxymetamphetamine (Ecstasy) induces c-fos-like protein and mRNA in rat organotypic dorsal striatal slices. Synapse 36: 75-83. (Pubitemid 30134127)
    • (2000) Synapse , vol.36 , Issue.1 , pp. 75-83
    • Schatz, D.S.1    Kaufmann, W.A.2    Schuligoi, R.3    Humpel, C.4    Saria, A.5
  • 55
    • 0036241656 scopus 로고    scopus 로고
    • Nestin expression persists in astrocytes of organotypic slice cultures from rat cortex
    • DOI 10.1016/S0736-5748(02)00003-5, PII S0736574802000035
    • Schmidt-Kastner, R, Humpel, C. (2002) Nestin expression persists in astrocytes of organotypic slice cultures from rat cortex. Int J Dev Neurosci 20: 29-38. (Pubitemid 34465458)
    • (2002) International Journal of Developmental Neuroscience , vol.20 , Issue.1 , pp. 29-38
    • Schmidt-Kastner, R.1    Humpel, C.2
  • 56
    • 0030946388 scopus 로고    scopus 로고
    • Short-term exposure to low concentrations of thapsigargin inhibits replication of cultured human vascular smooth muscle cells
    • DOI 10.1002/bjs.1800840315
    • Shukla, N, Jeremy, JY, Nicholl, P, Krijgsman, B, Stansby, G, Hamilton, G. (1997) Short-term exposure to low concentrations of thapsigargin inhibits replication of cultured human vascular smooth muscle cells. Br J Surg 84: 325-330. (Pubitemid 27141704)
    • (1997) British Journal of Surgery , vol.84 , Issue.3 , pp. 325-330
    • Shukla, N.1    Jeremy, J.Y.2    Nicholl, P.3    Krijgsman, B.4    Stansby, G.5    Hamilton, G.6
  • 57
    • 0035895758 scopus 로고    scopus 로고
    • Thapsigargin inhibits angiogenesis in the rat isolated aorta: Studies on the role of intracellular calcium pools
    • DOI 10.1016/S0008-6363(00)00269-8, PII S0008636300002698
    • Shukla, N, Freeman, N, Gadsdon, P, Angelini, GD, Jeremy, JY. (2001) Thapsigargin inhibits angiogensis in the rat isolated aorta: studies on the role of intracellular calcium pools. Cardiovasc Res 49: 681-689. (Pubitemid 32146431)
    • (2001) Cardiovascular Research , vol.49 , Issue.3 , pp. 681-689
    • Shukla, N.1    Freeman, N.2    Gadsdon, P.3    Angelini, G.D.4    Jeremy, J.Y.5
  • 58
    • 0035947768 scopus 로고    scopus 로고
    • Endothelial cell laminin isoforms, laminins 8 and 10, play decisive roles in T cell recruitment across the blood-brain barrier in experimental autoimmune encephalomyelitis
    • DOI 10.1083/jcb.153.5.933
    • Sixt, M, Engelhardt, B, Pausch, F, Hallmann, R, Vendler, O, Sorokin, LM. (2001) Endothelial cell laminin isoforms, laminins 8 and 10, play decesive roles in T cell recruitment across the blood-brain barrier in experimental autoimmune encephalomyelities. J Cell Biol 153: 933-945. (Pubitemid 34289234)
    • (2001) Journal of Cell Biology , vol.153 , Issue.5 , pp. 933-945
    • Sixt, M.1    Engelhardt, B.2    Pausch, F.3    Hallmann, R.4    Wendler, O.5    Sorokin, L.M.6
  • 59
    • 0025805120 scopus 로고
    • A simple method for organotypic cultures of nervous tissue
    • Stoppini, L, Buch, PA, Muller, D. (1991) A simple method for organotypic cultures of nervous tissue. J Neurosci Methods 37: 173-182.
    • (1991) J Neurosci Methods , vol.37 , pp. 173-182
    • Stoppini, L.1    Buch, P.A.2    Muller, D.3
  • 60
    • 0028120897 scopus 로고
    • Death of developing septal cholinergic neurons following NGF withdrawal in vitro: Protection by protein synthesis inhibition
    • Svendsen, CN, Kew JN, Staley K, Sofroniew MV. (1994) Death of developing septal cholinergic neurons following NGF withdrawal in vitro: protection by protein synthesis inhibition. J Neurosci 14: 75-87. (Pubitemid 24022099)
    • (1994) Journal of Neuroscience , vol.14 , Issue.1 , pp. 75-87
    • Svendsen, C.N.1    Kew, J.N.C.2    Staley, K.3    Sofroniew, M.V.4
  • 61
    • 34250792792 scopus 로고    scopus 로고
    • Caspase-dependent apoptosis induced by thapsigargin was prevented by glycogen synthase kinase-3 inhibitors in cultured rat cortical neurons
    • DOI 10.1007/s11064-007-9310-4
    • Takadera, T, Fujibayashi, M, Kaniyu, H, Sakota N, Ohyashiki, T. (2007) Caspase-dependent apoptosis induced by thapsigargin was prevented by glycogen synthase kinase-3 inhibitors in cultured rat cortical neurons. Neurochem Res 32: 1336-1342. (Pubitemid 46988194)
    • (2007) Neurochemical Research , vol.32 , Issue.8 , pp. 1336-1342
    • Takadera, T.1    Fujibayashi, M.2    Kaniyu, H.3    Sakota, N.4    Ohyashiki, T.5
  • 65
    • 68549103140 scopus 로고    scopus 로고
    • Survival of cholinergic forebrain neurons in developing p75NGFR-deficient mice
    • Van der Zee, CEEM, Ross, GM, Riopelle, RJ, Hagg, T. (1996) Survival of cholinergic forebrain neurons in developing p75NGFR-deficient mice. Science 110: 641-651.
    • (1996) Science , vol.110 , pp. 641-651
    • Van Der Zee, C.1    Ross, G.M.2    Riopelle, R.J.3    Hagg, T.4
  • 67
    • 0031776912 scopus 로고    scopus 로고
    • Bcl-2 protects against apoptosis in neuronal cell line caused by thapsigargin-induced depletion of intracellular calcium stores
    • Wei, H, Wei, W, Bredesen, DE, Perry, DC. (1998) Bcl-2 protects against apoptosis in neuronal cell line caused by thapsigargin-induced depletion of intracellular calcium stores. J Neurochem 70: 2305-2314. (Pubitemid 28252356)
    • (1998) Journal of Neurochemistry , vol.70 , Issue.6 , pp. 2305-2314
    • Wei, H.1    Wei, W.2    Bredesen, D.E.3    Perry, D.C.4
  • 68
    • 0035793027 scopus 로고    scopus 로고
    • Nerve growth factor and glial cell line-derived neurotrophic factor restore the cholinergic neuronal phenotype in organotypic brain slices of the basal nucleus of Meynert
    • DOI 10.1016/S0306-4522(00)00452-8, PII S0306452200004528
    • Weis, C, Marksteiner, J, Humpel, C. (2001) Nerve growth factor and glial cell line-derived neurotrophic factor restore the cholinergic phenotype in organotypic brain slices of the basal nucleus of Meynert. Neuroscience 102: 129-138. (Pubitemid 32171859)
    • (2001) Neuroscience , vol.102 , Issue.1 , pp. 129-138
    • Weis, C.1    Marksteiner, J.2    Humpel, C.3
  • 70
    • 0020397384 scopus 로고
    • Alzheimer's disease-correlation of cortical choline acetyltransferase activity with the severity of dementia and histological abnormalities
    • Wilcock, GK, Esiri, MM, Bowen, DM, Smith, CC. (1982) Alzheimer's disease-correlation of cortical choline acetyltransferase activity with the severity of dementia and histological abnormalities. J Neurol Sci 57: 407-417.
    • (1982) J Neurol Sci , vol.57 , pp. 407-417
    • Wilcock, G.K.1    Esiri, M.M.2    Bowen, D.M.3    Smith, C.C.4
  • 71
    • 0031875257 scopus 로고    scopus 로고
    • Cholinergic strategies for Alzheimer's disease
    • Winkler, J, Thal, LJ, Gage, FH, Fisher, LJ. (1998) Cholinergic strategies for Alzheimer's disease. J Mol Med 76: 555-567
    • (1998) J Mol Med , vol.76 , pp. 555-567
    • Winkler, J.1    Thal, L.J.2    Gage, F.H.3    Fisher, L.J.4
  • 73
    • 0141959268 scopus 로고    scopus 로고
    • Distribution of Flk-1 and Flt-1 receptores in neonatal and adult rat brains
    • Yang, SZ, Zhang, LM, Huang, YL, Sun, FY. (2003) Distribution of Flk-1 and Flt-1 receptores in neonatal and adult rat brains. Anat Rec 274A: 851-856.
    • (2003) Anat Rec 274A , pp. 851-856
    • Yang, S.Z.1    Zhang, L.M.2    Huang, Y.L.3    Sun, F.Y.4
  • 74
    • 0038582538 scopus 로고    scopus 로고
    • Tumor necrosis factor-α triggers cell death of sensitized potassium chloride-stimulated cholinergic neurons
    • DOI 10.1016/S0169-328X(03)00092-5
    • Zassler, B, Weis, C, Humpel, C. (2003) Tumor necrosis factor-alpha triggers cell death of sensitized potassium chloride-stimulated cholinergic neurons. Mol Brain Res 113: 78-85. (Pubitemid 36579069)
    • (2003) Molecular Brain Research , vol.113 , Issue.1-2 , pp. 78-85
    • Zassler, B.1    Weis, C.2    Humpel, C.3
  • 75
    • 12344322318 scopus 로고    scopus 로고
    • Urea enhances the nerve growth factor-induced neuroprotective effect on cholinergic neurons in organotypic rat brain slices
    • DOI 10.1016/j.neuroscience.2004.09.010, PII S0306452204008346
    • Zassler, B, Dechant, G, Humpel, C. (2005) Urea enhances the nerve growth factor-induced neuroprotective effect on cholinergic neurons in organotypic rat brain slices. Neuroscience 130: 317-323. (Pubitemid 40125470)
    • (2005) Neuroscience , vol.130 , Issue.2 , pp. 317-323
    • Zassler, B.1    Dechant, G.2    Humpel, C.3
  • 76
    • 0033825627 scopus 로고    scopus 로고
    • Oxidative stress and genetics in the pathogenesis of Parkinon's disease
    • Zhang, Y, Dawson, VL, Dawson, TM. (2000) Oxidative stress and genetics in the pathogenesis of Parkinon's disease. Neurobiol Dis 7: 240-250.
    • (2000) Neurobiol Dis , vol.7 , pp. 240-250
    • Zhang, Y.1    Dawson, V.L.2    Dawson, T.M.3
  • 78
    • 0033795839 scopus 로고    scopus 로고
    • Excitatory amino acid neurotoxicity and modulation of glutamate receptor expression in organotypic brain slice cultures
    • DOI 10.1007/s007260070029
    • Zimmer, J, Kristensen, BW, Jakobsen, B, Noraberg, J. (2000) Excitatory amino acid neurotoxicity and modulation of glutamate receptor expression in organotypic brain slice cultures. Amino Acids 19: 7-21. (Pubitemid 30738784)
    • (2000) Amino Acids , vol.19 , Issue.1 , pp. 7-21
    • Zimmer, J.1    Kristensen, B.W.2    Jakobsen, B.3    Noraberg, J.4


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