In vivo and in vitro anti-cancer activity of thermo-sensitive and photo-crosslinkable doxorubicin hydrogels composed of chitosan-doxorubicin conjugates

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 73, Issue 1, 2009, Pages 59-65

  Cho, Young Il ^a,b   Park, Shinyoung ^b   Jeong, Seo Young ^a   Yoo, Hyuk Sang ^b  

^a Kyung Hee University   (South Korea)

^b Kangwon National University   (South Korea)

Author keywords

Anti cancer; Chitosan; Conjugate; Doxorubicin; Hydrogel; Pluronic

Indexed keywords

CHITOSAN; DOXORUBICIN; METHACRYLIC ACID; OLIGOSACCHARIDE; POLOXAMER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; CROSS LINKING; CYTOTOXICITY; DEGRADATION KINETICS; DRUG RELEASE; HEAT SENSITIVITY; HUMAN; HUMAN CELL; HYDROGEL; HYDROPHILICITY; IN VITRO STUDY; IN VIVO STUDY; INCUBATION TEMPERATURE; LUNG ADENOCARCINOMA; MOUSE; NONHUMAN; NUDE MOUSE; REVERSED PHASE LIQUID CHROMATOGRAPHY; SURVIVAL RATE; SUSTAINED RELEASE FORMULATION; TEMPERATURE; TREATMENT OUTCOME; TUMOR VOLUME; ULTRAVIOLET RADIATION;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CHITOSAN; CROSS-LINKING REAGENTS; DELAYED-ACTION PREPARATIONS; DOXORUBICIN; DRUG COMBINATIONS; HOT TEMPERATURE; HUMANS; HYDROGELS; LIGHT; MICE; MICE, NUDE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 68349158961     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2009.04.010     Document Type: Article

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