Controlled release of paclitaxel from photocrosslinked chitosan hydrogels and its subsequent effect on subcutaneous tumor growth in mice

Journal of Controlled Release

Volumn 110, Issue 1, 2005, Pages 79-89

  Obara, Kiyohaya ^a   Ishihara, Masayuki ^a   Ozeki, Yuichi ^a   Ishizuka, Takamitsu ^a   Hayashi, Takuya ^a   Nakamura, Shingo ^a   Saito, Yoshio ^b   Yura, Hirofumi ^b   Matsui, Takemi ^a   Hattori, Hidemi ^a   Takase, Bonpei ^a   Ishihara, Miya ^a   Kikuchi, Makoto ^a   Maehara, Tadaaki ^a  

^a NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

^b NeTech Inc   (Japan)

Author keywords

Chitosan hydrogel; Drug delivery system; Paclitaxel; Regional drug delivery

Indexed keywords

CHITOSAN HYDROGEL; DRUG DELIVERY SYSTEM; PACLITAXEL; REGIONAL DRUG DELIVERY;

ANGIOGRAPHY; CELLS; CROSSLINKING; DEGRADATION; PHOSPHATES; SALINE WATER; TUMORS;

HYDROGELS;

CD34 ANTIGEN; CHITOSAN; CREMOPHOR; PACLITAXEL; PHOSPHATE BUFFERED SALINE;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AQUEOUS SOLUTION; ARTICLE; BIOLOGICAL ACTIVITY; CANCER CELL; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; CROSS LINKING; DEGRADATION; DRUG ACTIVITY; DRUG EFFECT; GROWTH INHIBITION; HUMAN; HUMAN CELL; HYDROGEL; IN VITRO STUDY; IN VIVO STUDY; IRRADIATION; LEWIS CARCINOMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SUBCUTANEOUS TISSUE TUMOR; TUMOR GROWTH; ULTRAVIOLET RADIATION;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CARCINOMA, LEWIS LUNG; CELL LINE, TUMOR; CHITOSAN; DELAYED-ACTION PREPARATIONS; DIFFUSION; DRUG CARRIERS; DRUG STABILITY; ENDOTHELIAL CELLS; HYDROGELS; INJECTIONS, SUBCUTANEOUS; MALE; MICE; MICE, INBRED C57BL; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; PACLITAXEL; PHOTOCHEMISTRY; SKIN NEOPLASMS;

EID: 28244491939     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2005.09.026     Document Type: Article

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