Evaluation of the antiulcerogenic activity of Maytenus robusta (Celastraceae) in different experimental ulcer models

Journal of Ethnopharmacology

Volumn 113, Issue 2, 2007, Pages 252-257

  de Andrade, Sérgio Faloni ^b   Lemos, Marivane ^a   Comunello, Eros ^b   Noldin, Vânia Floriani ^a   Filho, Valdir Cechinel ^b   Niero, Rivaldo ^b  

^a UNIVERSIDADE DO OESTE DE SANTA CATARINA   (Brazil)

^b UNIVERSIDADE DO VALE DO ITAJAÍ   (Brazil)

Author keywords

Antiulcerogenic activity; Celastraceae; Gastric secretion; Maytenus robusta

Indexed keywords

ALCOHOL; ALCOHOL DERIVATIVE; ANTIULCER AGENT; CIMETIDINE; INDOMETACIN; MAYTENUS ROBUSTA EXTRACT; NONSTEROID ANTIINFLAMMATORY AGENT; OMEPRAZOLE; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELASTRACEAE; CHEMOPROPHYLAXIS; CONTROLLED STUDY; DISEASE MODEL; DOSE RESPONSE; DRUG ACTIVITY; DRUG DETERMINATION; DRUG DOSE COMPARISON; EXPERIMENTAL MODEL; LIGATION; MALE; NONHUMAN; PHYTOTHERAPY; PYLORUS; RAT; STOMACH CONTENT; STOMACH JUICE; STOMACH PH; STOMACH PROTECTION; STOMACH SECRETION; STOMACH ULCER; STRESS;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTI-ULCER AGENTS; BRAZIL; CIMETIDINE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; GASTRIC ACID; GASTRIC ACIDITY DETERMINATION; HYDROGEN-ION CONCENTRATION; INDOMETHACIN; MALE; MAYTENUS; OMEPRAZOLE; PLANT EXTRACTS; PLANT LEAVES; RATS; RATS, WISTAR; SEVERITY OF ILLNESS INDEX; STOMACH ULCER;

CELASTRACEAE; MAYTENUS; MAYTENUS ILICIFOLIA;

EID: 34547757862     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2007.06.002     Document Type: Article

References (44)

1. Andrade S.F., Antoniolli D., Comunello E., Cardoso L.G.V., Carvalho J.C.T., and Bastos J.K. Antiulcerogenic activity of crude extract, fractions and populnoic acid isolated from Austroplenckia populnea (Celastraceae). Zeitschrift fur Naturforschung 61c (2006) 329-333
2. Andrikopoulos N.K., Kaliora A.C., Assimopolou N.A., and Papapeorgiou V.P. Biological activity of some naturally occurring resins, gums and pigments against in vitro LDL oxidation. Phytotherapy Research 7 (2003) 501-507
3. 2 receptors antagonist in cases of gastric ulcers. Nihon University Journal Medical 28 (1986) 69-74
4. Balbach, A., 1980. A flora nacional na medicina doméstica. 2a ed., Vida Plena, São Paulo, 1980, p. 34.
5. Barocelli E., Chiavarini M., Ballabeni V., Barlocco D., Vianello P., Dal Piaz V., and Impicciatore M. Study of the antisecretory and antiulcer mechanism of new indenopyridazinone derivative in rats. Pharmacological Research 35 (1997) 487-492
6. Basile A.C., Sertié J.A.A., Panizza S., Oshiro T.T., and Azzolini C.A. Pharmacological assay of Casearia silvestris. I. Preventive anti-ulcer activity and toxicity of the leaf crude extract. Journal of Ethnopharmacology 30 (1990) 185-197
7. Belaiche J., Burette A., De Vos M., Louis E., Huybrechts M., and Deltenre M. Study Group of NSAID-GI complications. Observational survey of NSAID-related upper gastro-intestinal adverse events in Belgium. Acta Gastroenterologic Belgiam 65 (2002) 65-73
8. Bighetti A.E., Antônio M.A., Kohn L.K., Rehder V.L.G., Foglio M.A., Possenti A., Vilela L., and Carvalho J.E. Antiulcerogenic activity of a crude hydroalcoholic extract and coumarin isolated from Mikania laevigata Schultz Bip. Phytomedicine 12 (2005) 72-77
9. Bruning R., and Wagner H. Übersicht über die celastraceen-inhaltsstoffe: Chemie, chemotaxonomie, biosynthese, pharmakologie. Phytochemistry 17 (1978) 1821-1858
10. Corrêa, M.P., 1984. Dicionário das plantas úteis do Brasil e das exóticas cultivadas, vol. 6, Imprensa Nacional, Rio de Janeiro, pp. 134-135.
11. Farnsworth N.R., and Soejarto D.D. Global importance of medicinal plants. In: Akerele O., Heywood V., and Synge H. (Eds). Conservation of Medicinal Plants (1991), Cambridge University Press, Cambridge 25-51
12. Gonzalez J.G., Monache G.D., Monache F.D., and Marini-Bettolò G.B. Chuchuasca-a drug used in folk medicine in the Amazonian and Andean areas. A chemical study of Maytenus leavis. Journal of Ethnopharmacology 5 (1982) 73-77
13. Gonzalez F.G., Portela T.Y., Stipp E.J., and Di Stasi L.C. Antiulcerogenic and analgesic effects of Maytenus aquifolium, Sorocea bomplandii and Zolernia ilicifolia. Journal of Ethnopharmacology 77 (2001) 41-47
14. Gonzalez F.G., and Di Stasi L.C. Antiulcerogenic and analgesic activities of the leaves of Wilbrandia ebracteata in mice. Phytomedicine 9 (2002) 125-134
15. Hayllar J., and Bjarnason I. NSAIDs, Cox-2 inhibitors, and the gut. Lancet 346 (1995) 521-522
16. Itokawa H., Shirota O., Ikuta H., Morita H., Takeya K., and Itaka Y. Triterpenes from Maytenus ilicifolia. Phytochemistry 30 (1991) 3713-3716
17. Jorge R.M., Leite J.P.V., Oliveira A.B., and Tagliati C.A. Evaluation of antinociceptive, anti-inflammatory and antiulcerogenic activities of Maytenus ilicifolia. Journal of Ethnopharmacology 94 (2004) 93-100
18. Larson R.A. The antioxidants of higher plants. Phytochemistry 27 (1998) 969-978
19. Leite J.P.V., Rastrelli L., Romussi G., Oliveira A.B., Vilegas J.H.Y., Vilegas W., and Pizza C. Isolation and HPLC quantitative analysis of flavonoid glycosids from Brasilian beverages (Maytenus ilicifolia and Maytenus aquifolium). Journal of Agricultural & Food Chemistry 49 (2001) 3796-3801
20. Lewis D.A., and Hanson P.J. Anti-ulcer drugs of plant origin. In: Ellis G.P., and West G.B. (Eds). Progress in Medicinal Chemistry vol. 28 (1991), Elsevier Science Publishers 201-231
21. Martin M.J., La-Casa C., Alarcon-de-Lastra C., Cabeza J., Villegas I., and Moltiva V. Anti-oxidant mechanisms involved in gastroprotective effects of quercetin. Zeistschrift fur Naturforschung C 52 (1998) 82-88
22. Miller J.P., and Faragher E.B. Relapse of duodenal ulcer: does it matter which drug is used in initial treatment. British Medical Journal 293 (1986) 1117-1118
23. Morimoto Y., Shimohara K., Oshima S., and Sukamoto T. Effects of the new anti-ulcer agent KB-5492 on experimental gastric mucosal lesions and gastric mucosal defensive factors, as compared to those of terprenone and cimetidine. Japanese Journal of Pharmacology 57 (1991) 595-605
24. Mutoh H., Hiraishi H., Ota S., Ivey K.J., Terano A., and Sugimoto T. Role of oxygen radicals in ethanol-induced damage to cultured gastric mucosal cells. The American Journal of Physiology 258 (1990) 603-609
25. Niero R., Moser R., Busato A.C.B., Yunes R.A., Reis A., and Cechinel-Filho V. A comparative chemical study of Maytenus ilicifolia Mart. Reiss and Maytenus robusta Reiss (Celastraceae). Zeitschrift fur Naturforschung 56c (2001) 158-161
26. Niero R., Mafra A.P., Lenzi A.C., Cechinel-Filho V., Tischer C.A., Malheiros A., Souza M.M., Yunes R.A., and Monache F.D. A new triterpene with antinociceptive activity from Maytenus robusta. Natural Products Research. 20 (2006) 1315-1320
27. Nwafor P.A., Okwuasaba F.K., and Binda L.G. Antidiarrhoeal and antiulcerogenic effects of methanolic extract of Asparagus pubescens root in rats. Journal of Ethnopharmacology 72 (2000) 421-427
28. Oliveira D.M., Silva G.D.F., Duarte L.P., and Vieira-Filho S.A. Chemical constituents isolated from roots of Maytenus acanthophylla Reissek (Celastraceae). Biochemical Systematics and Ecology 34 (2006) 661-665
29. Ohshima H., Yoshie Y., Auriol S., and Gilbert I. Antioxidant and pro-oxidant actions of flavonoids: effects on DNA damage induced by nitric oxide, peroxynitrite and nitroxyl anion. Free Radical Biology and Medicine 25 (1998) 1057-1065
30. Pihan G., Regillo C., and Szabo S. Free radicals and lipid peroxidation in ethanol- or aspirin-induced gastric mucosa injury. Digestive Diseases and Sciences 32 (1987) 1395-1401
31. Piper D.W., and Stiel D.D. Pathogenesis of chronic peptic ulcer, current thinking and clinical implications. Medical Progress 2 (1986) 7-10
32. Queiroga C.L., Silva G.F., Dias P.C., Possenti A., and Carvalho J.E. Evaluation of the antiulcerogenic activity of friedelan-3β-ol and friedelin isolated from Maytenus ilicifolia (Celastraceae). Journal of Ethnopharmacology 72 (2000) 465-468
33. Rainsford K.D. The effect of 5-lipoxygenase inhibitors and leukotriene antagonists on the development of gastric lesions induced by nonsteroidal antiinflammatory drugs in mice. Agents and Action 21 (1987) 316-319
34. Sairam K., Rao C.V., Babu M.D., Kumar K.V., Agrawal V.K., and Goel R.K. Antiulcerogenic effect of methanolic extract of Emblica officinalis: an experimental study. Journal of Ethnopharmacology 82 (2002) 1-9
35. Salim A.S. Removing oxygen derived free radicals stimulates healing of ethanol induced erosive gastritis in the rat. Digestion 47 (1990) 24-28
36. Shay H., Komarov S.A., Fels S.S., Meranze D., Gruenstein M., and Siplet H. A simple method for the uniform production of gastric ulceration in the rat. Gastroenterology 5 (1945) 43-61
37. Silva J.L., Silva R.P., Jorge R.M., Fátima Silva G.D., Vieira Filho S.A., Fonseca A.P.N.D., and Tagliati C.A. Avaliação da atividade antiulcerogênica da Maytenus truncata Reiss (Celastraceae). Brazilian Journal of Pharmacognosy 15 (2005) 30-35
38. Singh S., and Majumdar D.K. Evaluation of the gastric activity of fixed oil of Ocimum sanctum (Holy Basil). Journal of Ethnopharmacology 65 (1999) 13-19
39. Spivey A.C., Weston M., and Woodhead S. Celastraceae sesquiterpenoids: biological activity and synthesis. Chemical Society Reviews 31 (2002) 43-59
40. Sosa S., Morelli C.F., Tubaro A., Cairoli P., Speranza G., and Manitto P. Anti-inflammatory activity of Maytenus senegalensis root extracts and of maytenoic acid. Phytomedicine 14 (2007) 109-114
41. a ed. (2001), Herbarium Laboratório Botânico, Curitiba p. 128
42. Tiberti, L.A., Yariwake, J.H., Ndjoko, K., Hostettmann, K., 2007. Identification of flavonols in leaves of Maytenis ilicifolia and M. aquifolium (Celastraceae) by LC/UV/MS analysis. Journal of Chromatography B, 846, 378-384.
43. Vilegas W., Sanommiya M., Rastrelli L., and Pizza C. Isolation and structure elucidation of two new flavonoid glycosides from the infusion of Maytenus aquifolium leaves. Evaluation of the antiulcer activity of the infusion. Journal of Agricultural and Food Chemistry 47 (1999) 403-406
44. Zayachkivska O.S., Konturek S.J., Drozdowicz D., Konturek P.C., Brzozowski T., and Ghegotsky M.R. Gastroprotective effects of flavonoids in plant extracts. Journal of Physiology and Pharmacology 56 (2005) 219-231