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Volumn 7, Issue 5, 2009, Pages 515-525

Can lactoferrin prevent neonatal sepsis and necrotizing enterocolitis?

Author keywords

Broad spectrum antimicrobial activity; Immunity; Inflammation; Lactoferrin; Necrotizing enterocolitis; Neonate; Sepsis

Indexed keywords

AMOXICILLIN; AMPHOTERICIN B; ANTIBIOTIC AGENT; CLARITHROMYCIN; FLUCONAZOLE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; INTERLEUKIN 10; INTERLEUKIN 4; INTERLEUKIN 6; LACTOFERRIN; LYSOZYME; MINOCYCLINE; NAFCILLIN; PROBIOTIC AGENT; PYRIMETHAMINE; RIBAVIRIN; TETRACYCLINE; THROMBOCYTE ACTIVATING FACTOR; TUMOR NECROSIS FACTOR ALPHA; VANCOMYCIN; ANTIINFECTIVE AGENT; IMMUNOLOGIC FACTOR; NONSTEROID ANTIINFLAMMATORY AGENT;

EID: 68249158646     PISSN: 14787210     EISSN: 17448336     Source Type: Journal    
DOI: 10.1586/ERI.09.25     Document Type: Review
Times cited : (10)

References (143)
  • 1
    • 33749256460 scopus 로고    scopus 로고
    • Necrotising enterocolitis
    • Comprehensive review on necrotizing enterocolitis
    • Lin PW, Stoll BJ. Necrotising enterocolitis. Lancet 368(9543), 1271-1283 (2006). •• Comprehensive review on necrotizing enterocolitis.
    • (2006) Lancet , vol.368 , Issue.9543 , pp. 1271-1283
    • Lin, P.W.1    Stoll, B.J.2
  • 3
    • 22244462944 scopus 로고    scopus 로고
    • Very low birth weight preterm infants with early onset neonatal sepsis: The predominance of Gram-negative infections continues in the National Institute of Child Health and Human Development Neonatal Research Network, 2002-2003
    • Stoll BJ, Hansen NI, Higgins RD et al. Very low birth weight preterm infants with early onset neonatal sepsis: the predominance of Gram-negative infections continues in the National Institute of Child Health and Human Development Neonatal Research Network, 2002-2003. Pediatr. Infect. Dis. J. 24(7), 635-639 (2005).
    • (2005) Pediatr. Infect. Dis. J. , vol.24 , Issue.7 , pp. 635-639
    • Stoll, B.J.1    Hansen, N.I.2    Higgins, R.D.3
  • 4
    • 59449088862 scopus 로고    scopus 로고
    • Antibiotic-resistant bugs in the 21st century - a clinical super-challenge
    • Editorial on the current resistance of bacteria
    • Arias CA, Murray BE. Antibiotic-resistant bugs in the 21st century - a clinical super-challenge. N. Engl. J. Med. 360(5), 439-443 (2009). • Editorial on the current resistance of bacteria.
    • (2009) N. Engl. J. Med. , vol.360 , Issue.5 , pp. 439-443
    • Arias, C.A.1    Murray, B.E.2
  • 5
    • 0032745094 scopus 로고    scopus 로고
    • Inflammatory mechanisms in neonatal chronic lung disease
    • Speer CP. Inflammatory mechanisms in neonatal chronic lung disease. Eur. J. Pediatr. 158(Suppl. 1), S18-S22 (1999).
    • (1999) Eur. J. Pediatr. , vol.158 , Issue.SUPPL. 1
    • Speer, C.P.1
  • 6
    • 33646678434 scopus 로고    scopus 로고
    • Neonatal infection and long-term neurodevelopmental outcome in the preterm infant
    • DOI 10.1097/01.qco.0000224825.57976.87, PII 0000143220060600000012
    • Adams-Chapman I, Stoll BJ. Neonatal infection and long-term neurodevelopmental outcome in the preterm infant. Curr. Opin. Infect. Dis. 19(3), 290-297 (2006). (Pubitemid 43740369)
    • (2006) Current Opinion in Infectious Diseases , vol.19 , Issue.3 , pp. 290-297
    • Adams-Chapman, I.1    Stoll, B.J.2
  • 7
    • 33646471734 scopus 로고    scopus 로고
    • Estimating the causes of 4 million neonatal deaths in the year 2000
    • Lawn JE, Wilczynska-Ketende K, Cousens SN. Estimating the causes of 4 million neonatal deaths in the year 2000. Int. J. Epidemiol. 35(3), 706-718 (2006).
    • (2006) Int. J. Epidemiol. , vol.35 , Issue.3 , pp. 706-718
    • Lawn, J.E.1    Wilczynska-Ketende, K.2    Cousens, S.N.3
  • 9
    • 33846894800 scopus 로고    scopus 로고
    • Trends in neonatal morbidity and mortality for very low birthweight infants
    • Current trends of neonatal mortality and morbidity
    • Fanaroff AA, Stoll BJ, Wright LL et al. Trends in neonatal morbidity and mortality for very low birthweight infants. Am. J. Obstet. Gynecol. 196(2), 147 e141-e148 (2007). •• Current trends of neonatal mortality and morbidity.
    • (2007) Am. J. Obstet. Gynecol. , vol.196 , Issue.2
    • Fanaroff, A.A.1    Stoll, B.J.2    Wright, L.L.3
  • 10
    • 0035219722 scopus 로고    scopus 로고
    • Very low birth weight outcomes of the National Institute of Child Health and Human Development Neonatal Research Network, January 1995 through December 1996
    • NICHD Neonatal Research Network
    • Lemons JA, Bauer CR, Oh W et al. Very low birth weight outcomes of the National Institute of Child Health and Human Development Neonatal Research Network, January 1995 through December 1996. NICHD Neonatal Research Network. Pediatrics 107(1), E1 (2001).
    • (2001) Pediatrics , vol.107 , Issue.1
    • Lemons, J.A.1    Bauer, C.R.2    Oh, W.3
  • 11
    • 0025296725 scopus 로고
    • Role of platelet activating factor and tumor necrosis factor-alpha in neonatal necrotizing enterocolitis
    • DOI 10.1016/S0022-3476(05)80661-4
    • Caplan MS, Hsueh W. Necrotizing enterocolitis: role of platelet activating factor, endotoxin, and tumor necrosis factor. J. Pediatr. 117(1 Pt 2), S47-S51 (1990). (Pubitemid 20201711)
    • (1990) Journal of Pediatrics , vol.116 , Issue.6 , pp. 960-964
    • Caplan, M.S.1    Sun, X.-M.2    Hsueh, W.3    Hageman, J.R.4
  • 12
    • 0025296725 scopus 로고
    • Role of platelet activating factor and tumor necrosis factor-α in neonatal necrotizing enterocolitis
    • Caplan MS, Sun XM, Hseuh W, Hageman JR. Role of platelet activating factor and tumor necrosis factor-α in neonatal necrotizing enterocolitis. J. Pediatr. 116(6), 960-964 (1990).
    • (1990) J. Pediatr. , vol.116 , Issue.6 , pp. 960-964
    • Caplan, M.S.1    Sun, X.M.2    Hseuh, W.3    Hageman, J.R.4
  • 14
  • 15
    • 1542410492 scopus 로고    scopus 로고
    • Molecular aspects of intestinal epithelial cell-bacterial interactions that determine the development of intestinal inflammation
    • Neish AS. Molecular aspects of intestinal epithelial cell-bacterial interactions that determine the development of intestinal inflammation. Inflamm. Bowel Dis. 10(2), 159-168 (2004).
    • (2004) Inflamm. Bowel Dis. , vol.10 , Issue.2 , pp. 159-168
    • Neish, A.S.1
  • 16
    • 0033029932 scopus 로고    scopus 로고
    • Circulating pro- and counterinflammatory cytokine levels and severity in necrotizing enterocolitis
    • Edelson MB, Bagwell CE, Rozycki HJ. Circulating pro- and counterinflammatory cytokine levels and severity in necrotizing enterocolitis. Pediatrics 103(4 Pt 1), 766-771 (1999).
    • (1999) Pediatrics , vol.103 , Issue.4 PART 1 , pp. 766-771
    • Edelson, M.B.1    Bagwell, C.E.2    Rozycki, H.J.3
  • 18
    • 26844465142 scopus 로고    scopus 로고
    • Cytokine elaboration in critically ill infants with bacterial sepsis, necrotizing entercolitis, or sepsis syndrome: Correlation with clinical parameters of inflammation and mortality
    • DOI 10.1016/j.jpeds.2005.04.037, PII S002234760500346X
    • Harris MC, D'Angio CT, Gallagher PR, Kaufman D, Evans J, Kilpatrick L. Cytokine elaboration in critically ill infants with bacterial sepsis, necrotizing entercolitis, or sepsis syndrome: correlation with clinical parameters of inflammation and mortality. J. Pediatr. 147(4), 462-468 (2005). (Pubitemid 41446539)
    • (2005) Journal of Pediatrics , vol.147 , Issue.4 , pp. 462-468
    • Harris, M.C.1    D'Angio, C.T.2    Gallagher, P.R.3    Kaufman, D.4    Evans, J.5    Kilpatrick, L.6
  • 19
    • 28344447990 scopus 로고    scopus 로고
    • Multifunctional roles of lactoferrin: A critical overview
    • DOI 10.1007/s00018-005-5369-8
    • Ward PP, Paz E, Conneely OM. Multifunctional roles of lactoferrin: a critical overview. Cell. Mol. Life Sci. 62(22), 2540-2548 (2005). (Pubitemid 41721229)
    • (2005) Cellular and Molecular Life Sciences , vol.62 , Issue.22 , pp. 2540-2548
    • Ward, P.P.1    Paz, E.2    Conneely, O.M.3
  • 20
    • 0022416851 scopus 로고
    • Comparison of human lactoferrins from milk and neutrophilic leucocytes. Relative molecular mass, isoelectric point, iron-binding properties and uptake by the liver
    • Moguilevsky N, Retegui LA, Masson PL. Comparison of human lactoferrins from milk and neutrophilic leucocytes. Relative molecular mass, isoelectric point, iron-binding properties and uptake by the liver. Biochem. J. 229(2), 353-359 (1985). (Pubitemid 15232043)
    • (1985) Biochemical Journal , vol.229 , Issue.2 , pp. 353-359
    • Moguilevsky, N.1    Retegui, L.A.2    Masson, P.L.3
  • 22
    • 0031663661 scopus 로고    scopus 로고
    • Three-dimensional structure of lactoferrin. Implications for function, including comparisons with transferrin
    • Baker EN, Anderson BF, Baker HM et al. Three-dimensional structure of lactoferrin. Implications for function, including comparisons with transferrin. Adv. Exp. Med. Biol. 443, 1-14 (1998).
    • (1998) Adv. Exp. Med. Biol. , vol.443 , pp. 1-14
    • Baker, E.N.1    Anderson, B.F.2    Baker, H.M.3
  • 23
    • 0025957064 scopus 로고
    • Lysozyme, lactoferrin, and secretory immunoglobulin A content in breast milk: Influence of duration of lactation, nutrition status, prolactin status, and parity of mother
    • Hennart PF, Brasseur DJ, Delogne-Desnoeck JB, Dramaix MM, Robyn CE. Lysozyme, lactoferrin, and secretory immunoglobulin A content in breast milk: influence of duration of lactation, nutrition status, prolactin status, and parity of mother. Am. J. Clin. Nutr. 53(1), 32-39 (1991).
    • (1991) Am. J. Clin. Nutr. , vol.53 , Issue.1 , pp. 32-39
    • Hennart, P.F.1    Brasseur, D.J.2    Delogne-Desnoeck, J.B.3    Dramaix, M.M.4    Robyn, C.E.5
  • 24
    • 0015225776 scopus 로고
    • Lactoferrin in milk from different species
    • Masson PL, Heremans JF. Lactoferrin in milk from different species. Comp. Biochem. Physiol. B. 39(1), 119-129 (1971).
    • (1971) Comp. Biochem. Physiol. B. , vol.39 , Issue.1 , pp. 119-129
    • Masson, P.L.1    Heremans, J.F.2
  • 25
    • 0009665799 scopus 로고
    • An iron-binding protein common to many external secretions
    • Masson P, Heremans J, Dive C. An iron-binding protein common to many external secretions. Clinica Chimica Acta 14, 735-739 (1966).
    • (1966) Clinica Chimica Acta , vol.14 , pp. 735-739
    • Masson, P.1    Heremans, J.2    Dive, C.3
  • 26
    • 0014574791 scopus 로고
    • Lactoferrin, an iron-binding protein in neutrophilic leukocytes
    • Masson P, Heremans JF, Schonne E. Lactoferrin, an iron-binding protein in neutrophilic leukocytes. J. Exp. Med. 130, 643-658 (1969).
    • (1969) J. Exp. Med. , vol.130 , pp. 643-658
    • Masson, P.1    Heremans, J.F.2    Schonne, E.3
  • 27
  • 28
    • 0023736956 scopus 로고
    • Killing of Actinobacillus actinomycetemcomitans by human lactoferrin
    • Kalmar JR, Arnold RR. Killing of Actinobacillus actinomycetemcomitans by human lactoferrin. Infect. Immun. 56(10), 2552-2557 (1988).
    • (1988) Infect. Immun. , vol.56 , Issue.10 , pp. 2552-2557
    • Kalmar, J.R.1    Arnold, R.R.2
  • 29
    • 0027465990 scopus 로고
    • Antibacterial activity of lactoferrin and a pepsin-derived lactoferrin peptide fragment
    • Yamauchi K, Tomita M, Giehl TJ, Ellison RT 3rd. Antibacterial activity of lactoferrin and a pepsin-derived lactoferrin peptide fragment. Infect. Immun. 61(2), 719-728 (1993). (Pubitemid 23030865)
    • (1993) Infection and Immunity , vol.61 , Issue.2 , pp. 719-728
    • Yamauchi, K.1    Tomita, M.2    Giehl, T.J.3    Ellison III, R.T.4
  • 30
    • 0141918811 scopus 로고    scopus 로고
    • Lactoferrin - A multifunctional protein with antimicrobial properties
    • DOI 10.1016/S0161-5890(03)00152-4
    • Farnaud S, Evans RW. Lactoferrin - a multifunctional protein with antimicrobial properties. Mol. Immunol. 40(7), 395-405 (2003). (Pubitemid 37244032)
    • (2003) Molecular Immunology , vol.40 , Issue.7 , pp. 395-405
    • Farnaud, S.1    Evans, R.W.2
  • 31
    • 3342928851 scopus 로고    scopus 로고
    • The antimicrobial activity of lactoferrin: Current status and perspectives
    • DOI 10.1023/B:BIOM.0000027691.86757.e2
    • Orsi N. The antimicrobial activity of lactoferrin: current status and perspectives. Biometals 17(3), 189-196 (2004). (Pubitemid 38987136)
    • (2004) BioMetals , vol.17 , Issue.3 , pp. 189-196
    • Orsi, N.1
  • 33
    • 0019432648 scopus 로고
    • Bactericidal activity of human lactoferrin: Influence of physical conditions and metabolic state of the target microorganism
    • Arnold RR, Russell JE, Champion WJ, Gauthier JJ. Bactericidal activity of human lactoferrin: influence of physical conditions and metabolic state of the target microorganism. Infect. Immun. 32(2), 655-660 (1981).
    • (1981) Infect. Immun. , vol.32 , Issue.2 , pp. 655-660
    • Arnold, R.R.1    Russell, J.E.2    Champion, W.J.3    Gauthier, J.J.4
  • 34
    • 0024806389 scopus 로고
    • Bactericidal effect of lactoferrin on Legionella pneumophila: Effect of the physiological state of the organism
    • Bortner CA, Arnold RR, Miller RD. Bactericidal effect of lactoferrin on Legionella pneumophila: effect of the physiological state of the organism. Can. J. Microbiol. 35(11), 1048-1051 (1989).
    • (1989) Can. J. Microbiol. , vol.35 , Issue.11 , pp. 1048-1051
    • Bortner, C.A.1    Arnold, R.R.2    Miller, R.D.3
  • 35
    • 28344438950 scopus 로고    scopus 로고
    • Lactoferricin: A lactoferrin-derived peptide with antimicrobial, antiviral, antitumor and immunological properties
    • Gifford JL, Hunter HN, Vogel HJ. Lactoferricin: a lactoferrin-derived peptide with antimicrobial, antiviral, antitumor and immunological properties. Cell. Mol. Life Sci. 62(22), 2588-2598 (2005).
    • (2005) Cell. Mol. Life Sci. , vol.62 , Issue.22 , pp. 2588-2598
    • Gifford, J.L.1    Hunter, H.N.2    Vogel, H.J.3
  • 36
    • 0027232811 scopus 로고
    • Killing of Candida albicans by lactoferricin B, a potent antimicrobial peptide derived from the N-terminal region of bovine lactoferrin
    • Bellamy W, Takase M, Wakabayashi H, Kawase K, Tomita M. Antibacterial spectrum of lactoferricin B, a potent bactericidal peptide derived from the N-terminal region of bovine lactoferrin. J. Appl. Bacteriol. 73(6), 472-479 (1992). (Pubitemid 23160081)
    • (1993) Medical Microbiology and Immunology , vol.182 , Issue.2 , pp. 97-105
    • Bellamy, W.1    Wakabayashi, H.2    Takase, M.3    Kawase, K.4    Shimamura, S.5    Tomita, M.6
  • 39
    • 0035112330 scopus 로고    scopus 로고
    • Human lactoferrin and peptides derived from its N terminus are highly effective against infections with antibiotic-resistant bacteria
    • DOI 10.1128/IAI.69.3.1469-1476.2001
    • Nibbering PH, Ravensbergen E, Welling MM et al. Human lactoferrin and peptides derived from its N terminus are highly effective against infections with antibiotic-resistant bacteria. Infect. Immun. 69(3), 1469-1476 (2001). • Evidence of the efficacy of lactoferrin (Lf) against resistant bacteria. (Pubitemid 32187596)
    • (2001) Infection and Immunity , vol.69 , Issue.3 , pp. 1469-1476
    • Nibbering, P.H.1    Ravensbergen, E.2    Welling, M.M.3    Van Berkel, L.A.4    Van Berkel, P.H.C.5    Pauwels, E.K.J.6    Nuijens, J.H.7
  • 40
    • 28344457682 scopus 로고    scopus 로고
    • Lactoferrin: An important host defence against microbial and viral attack
    • DOI 10.1007/s00018-005-5372-0
    • Valenti P, Antonini G. Lactoferrin: an important host defence against microbial and viral attack. Cell. Mol. Life Sci. 62(22), 2576-2587 (2005). •• Comprehensive review on the antimicrobial effects of Lf. (Pubitemid 41721231)
    • (2005) Cellular and Molecular Life Sciences , vol.62 , Issue.22 , pp. 2576-2587
    • Valenti, P.1    Antonini, G.2
  • 41
    • 28344453346 scopus 로고    scopus 로고
    • Mammalian lactoferrin receptors: Structure and function
    • DOI 10.1007/s00018-005-5371-1
    • Suzuki YA, Lopez V, Lonnerdal B. Mammalian lactoferrin receptors: structure and function. Cell. Mol. Life Sci. 62(22), 2560-2575 (2005). • Review on human Lf receptors. (Pubitemid 41721230)
    • (2005) Cellular and Molecular Life Sciences , vol.62 , Issue.22 , pp. 2560-2575
    • Suzuki, Y.A.1    Lopez, V.2    Lonnerdal, B.3
  • 42
    • 33845464963 scopus 로고    scopus 로고
    • Lactoferrin activates macrophages via TLR4-dependent and -independent signaling pathways
    • Curran CS, Demick KP, Mansfield JM. Lactoferrin activates macrophages via TLR4-dependent and -independent signaling pathways. Cell. Immunol. 242(1), 23-30 (2006).
    • (2006) Cell. Immunol. , vol.242 , Issue.1 , pp. 23-30
    • Curran, C.S.1    Demick, K.P.2    Mansfield, J.M.3
  • 43
    • 28444462150 scopus 로고    scopus 로고
    • Lactoferrin: A modulator of immune and inflammatory responses
    • DOI 10.1007/s00018-005-5370-2
    • Legrand D, Elass E, Carpentier M, Mazurier J. Lactoferrin: a modulator of immune and inflammatory responses. Cell. Mol. Life Sci. 62(22), 2549-2559 (2005). •• Comprehensive review on the immunoregulatory effects of Lf. (Pubitemid 41722207)
    • (2005) Cellular and Molecular Life Sciences , vol.62 , Issue.22 , pp. 2549-2559
    • Legrand, D.1    Elass, E.2    Carpentier, M.3    Mazurier, J.4
  • 44
    • 17744405513 scopus 로고    scopus 로고
    • Lactoferrin down-regulates the LPS-induced cytokine production in monocytic cells via NF-κB
    • DOI 10.1016/S0008-8749(03)00006-6
    • Haversen L, Ohlsson BG, Hahn-Zoric M, Hanson LA, Mattsby-Baltzer I. Lactoferrin down-regulates the LPS-induced cytokine production in monocytic cells via NF-κB. Cell. Immunol. 220(2), 83-95 (2002). • Mechanism of the anti-inflammatory effect of Lf. (Pubitemid 36349060)
    • (2002) Cellular Immunology , vol.220 , Issue.2 , pp. 83-95
    • Haversen, L.1    Ohlsson, B.G.2    Hahn-Zoric, M.3    Hanson, L.A.4    Mattsby-Baltzer, I.5
  • 45
    • 0036379733 scopus 로고    scopus 로고
    • Differential effects of prophylactic, concurrent and therapeutic lactoferrin treatment on LPS-induced inflammatory responses in mice
    • Kruzel ML, Harari Y, Mailman D, Actor JK, Zimecki M. Differential effects of prophylactic, concurrent and therapeutic lactoferrin treatment on LPS-induced inflammatory responses in mice. Clin. Exp. Immunol. 130(1), 25-31 (2002).
    • (2002) Clin. Exp. Immunol. , vol.130 , Issue.1 , pp. 25-31
    • Kruzel, M.L.1    Harari, Y.2    Mailman, D.3    Actor, J.K.4    Zimecki, M.5
  • 46
    • 33748416650 scopus 로고    scopus 로고
    • Interactions of lactoferrin with cells involved in immune function
    • DOI 10.1139/O06-045
    • Legrand D, Elass E, Carpentier M, Mazurier J. Interactions of lactoferrin with cells involved in immune function. Biochem. Cell Biol. 84(3), 282-290 (2006). (Pubitemid 44341302)
    • (2006) Biochemistry and Cell Biology , vol.84 , Issue.3 , pp. 282-290
    • Legrand, D.1    Elass, E.2    Carpentier, M.3    Mazurier, J.4
  • 50
    • 3142608843 scopus 로고    scopus 로고
    • Enhanced clearance of Escherichia coli and Staphylococcus aureus in mice treated with cyclophosphamide and lactoferrin
    • DOI 10.1016/j.intimp.2004.05.002, PII S156757690400147X
    • Artym J, Zimecki M, Kruzel ML. Enhanced clearance of Escherichia coli and Staphylococcus aureus in mice treated with cyclophosphamide and lactoferrin. Int. Immunopharmacol. 4(9), 1149-1157 (2004). (Pubitemid 38900852)
    • (2004) International Immunopharmacology , vol.4 , Issue.9 , pp. 1149-1157
    • Artym, J.1    Zimecki, M.2    Kruzel, M.L.3
  • 51
    • 37249093508 scopus 로고    scopus 로고
    • Prophylaxis with lactoferrin, a novel antimicrobial agent, in a neonatal rat model of coinfection
    • DOI 10.1007/BF02877698
    • Venkatesh M, Pham D, Kong L, Weisman L. Prophylaxis with lactoferrin, a novel antimicrobial agent, enhances survival in a neonatal rat model of co-infection. Adv. Ther. 24(5), 941-954 (2007). (Pubitemid 350274771)
    • (2007) Advances in Therapy , vol.24 , Issue.5 , pp. 941-954
    • Venkatesh, M.P.1    Pham, D.2    Kong, L.3    Weisman, L.E.4
  • 52
    • 0034906217 scopus 로고    scopus 로고
    • Functional fragments of ingested lactoferrin are resistant to proteolytic degradation in the gastrointestinal tract of adult rats
    • Kuwata H, Yamauchi K, Teraguchi S et al. Functional fragments of ingested lactoferrin are resistant to proteolytic degradation in the gastrointestinal tract of adult rats. J. Nutr. 131(8), 2121-2127 (2001). (Pubitemid 32720641)
    • (2001) Journal of Nutrition , vol.131 , Issue.8 , pp. 2121-2127
    • Kuwata, H.1    Yamauchi, K.2    Teraguchi, S.3    Ushida, Y.4    Shimokawa, Y.5    Toida, T.6    Hayasawa, H.7
  • 53
    • 0026023387 scopus 로고
    • Origin of intact lactoferrin and its DNA-binding fragments found in the urine of human milk-fed preterm infants. Evaluation by stable isotopic enrichment
    • Hutchens TW, Henry JF, Yip TT et al. Origin of intact lactoferrin and its DNA-binding fragments found in the urine of human milk-fed preterm infants. Evaluation by stable isotopic enrichment. Pediatr. Res. 29(3), 243-250 (1991).
    • (1991) Pediatr. Res. , vol.29 , Issue.3 , pp. 243-250
    • Hutchens, T.W.1    Henry, J.F.2    Yip, T.T.3
  • 56
    • 33750614268 scopus 로고    scopus 로고
    • Enteric-formulated lactoferrin was more effectively transported into blood circulation from gastrointestinal tract in adult rats
    • DOI 10.1113/expphysiol.2006.035543
    • Takeuchi T, Jyonotsuka T, Kamemori N et al. Enteric-formulated lactoferrin was more effectively transported into blood circulation from gastrointestinal tract in adult rats. Exp. Physiol. 91(6), 1033-1040 (2006). (Pubitemid 44690815)
    • (2006) Experimental Physiology , vol.91 , Issue.6 , pp. 1033-1040
    • Takeuchi, T.1    Jyonotsuka, T.2    Kamemori, N.3    Kawano, G.4    Shimizu, H.5    Ando, K.6    Harada, E.7
  • 57
    • 0036191258 scopus 로고    scopus 로고
    • Effect of lactoferrin on Helicobacter felis induced gastritis
    • Dial EJ, Lichtenberger LM. Effect of lactoferrin on Helicobacter felis induced gastritis. Biochem. Cell Biol. 80(1), 113-117 (2002).
    • (2002) Biochem. Cell Biol. , vol.80 , Issue.1 , pp. 113-117
    • Dial, E.J.1    Lichtenberger, L.M.2
  • 59
    • 0036893659 scopus 로고    scopus 로고
    • Lactoferrin protects rabbits from Shigella flexneri-induced inflammatory enteritis
    • DOI 10.1128/IAI.70.12.7050-7053.2002
    • Gomez HF, Ochoa TJ, Herrera-Insua I, Carlin LG, Cleary TG. Lactoferrin protects rabbits from Shigella flexneri-induced inflammatory enteritis. Infect. Immun. 70(12), 7050-7053 (2002). (Pubitemid 35387941)
    • (2002) Infection and Immunity , vol.70 , Issue.12 , pp. 7050-7053
    • Gomez, H.F.1    Ochoa, T.J.2    Herrera-Insua, I.3    Carlin, L.G.4    Cleary, T.G.5
  • 60
    • 31344478777 scopus 로고    scopus 로고
    • Intraperitoneal injection of lactoferrin ameliorates severe albumin extravasation and neutrophilia in LPS-induced inflammation in neonatal rats
    • DOI 10.2220/biomedres.26.249
    • Yajima M, Yajima T, Kuwata T. Intraperitoneal injection of lactoferrin ameliorates severe albumin extravasation and neutrophilia in LPS-induced inflammation in neonatal rats. Biomed. Res. 26(6), 249-255 (2005). (Pubitemid 43137332)
    • (2006) Biomedical Research , vol.26 , Issue.6 , pp. 249-255
    • Yajima, M.1    Yajima, T.2    Kuwata, T.3
  • 61
    • 0033976996 scopus 로고    scopus 로고
    • Lactoferrin protects gut mucosal integrity during endotoxemia induced by lipopolysaccharide in mice
    • DOI 10.1023/A:1006935908960
    • Kruzel ML, Harari Y, Chen CY, Castro GA. Lactoferrin protects gut mucosal integrity during endotoxemia induced by lipopolysaccharide in mice. Inflammation 24(1), 33-44 (2000). (Pubitemid 30105938)
    • (2000) Inflammation , vol.24 , Issue.1 , pp. 33-44
    • Kruzel, M.L.1    Harari, Y.2    Chen, C.-Y.3    Castro, G.A.4
  • 62
    • 50849136183 scopus 로고    scopus 로고
    • Protective effects of lactoferrin against intestinal mucosal damage induced by lipopolysaccharide in human intestinal Caco-2 cells
    • Hirotani Y, Ikeda K, Kato R et al. Protective effects of lactoferrin against intestinal mucosal damage induced by lipopolysaccharide in human intestinal Caco-2 cells. Yakugaku Zasshi 128(9), 1363-1368 (2008).
    • (2008) Yakugaku Zasshi , vol.128 , Issue.9 , pp. 1363-1368
    • Hirotani, Y.1    Ikeda, K.2    Kato, R.3
  • 63
    • 0001295809 scopus 로고
    • The biological significance of the non-immunoglobulin protective proteins in milk: Lysozyme, lactoferrin, lactoperoxidase
    • Reiter B. The biological significance of the non-immunoglobulin protective proteins in milk: lysozyme, lactoferrin, lactoperoxidase. Devel. Dairy Chem. 3, 281-336 (1985).
    • (1985) Devel. Dairy Chem. , vol.3 , pp. 281-336
    • Reiter, B.1
  • 64
    • 34147147026 scopus 로고    scopus 로고
    • Lactoferrin induces concentration-dependent functional modulation of intestinal proliferation and differentiation
    • DOI 10.1203/pdr.0b013e3180332c8d
    • Buccigrossi V, de Marco G, Bruzzese E et al. Lactoferrin induces concentration-dependent functional modulation of intestinal proliferation and differentiation. Pediatr. Res. 61(4), 410-414 (2007). (Pubitemid 46569292)
    • (2007) Pediatric Research , vol.61 , Issue.4 , pp. 410-414
    • Buccigrossi, V.1    De Marco, G.2    Bruzzese, E.3    Ombrato, L.4    Bracale, I.5    Polito, G.6    Guarino, A.7
  • 66
    • 0036191042 scopus 로고    scopus 로고
    • Bovine lactoferrin and lactoferricin derived from milk: Production and applications
    • DOI 10.1139/o01-230
    • Tomita M, Wakabayashi H, Yamauchi K, Teraguchi S, Hayasawa H. Bovine lactoferrin and lactoferricin derived from milk: production and applications. Biochem. Cell Biol. 80(1), 109-112 (2002). (Pubitemid 34194235)
    • (2002) Biochemistry and Cell Biology , vol.80 , Issue.1 , pp. 109-112
    • Tomita, M.1    Wakabayashi, H.2    Yamauchi, K.3    Teraguchi, S.4    Hayasawa, H.5
  • 68
    • 44649198352 scopus 로고    scopus 로고
    • 28-day repeated dose oral toxicity of recombinant human apo-lactoferrin or recombinant human lysozyme in rats
    • Cerven D, DeGeorge G, Bethell D. 28-day repeated dose oral toxicity of recombinant human apo-lactoferrin or recombinant human lysozyme in rats. Regul. Toxicol. Pharmacol. 51(2), 162-167 (2008).
    • (2008) Regul. Toxicol. Pharmacol. , vol.51 , Issue.2 , pp. 162-167
    • Cerven, D.1    DeGeorge, G.2    Bethell, D.3
  • 70
    • 33846689322 scopus 로고    scopus 로고
    • Efficacy of rice-based oral rehydration solution containing recombinant human lactoferrin and lysozyme in Peruvian children with acute diarrhea
    • DOI 10.1097/MPG.0b013e31802c41b7, PII 0000517620070200000018
    • Zavaleta N, Figueroa D, Rivera J, Sanchez J, Alfaro S, Lonnerdal B. Efficacy of rice-based oral rehydration solution containing recombinant human lactoferrin and lysozyme in Peruvian children with acute diarrhea. J. Pediatr. Gastroenterol. Nutr. 44(2), 258-264 (2007). (Pubitemid 46188074)
    • (2007) Journal of Pediatric Gastroenterology and Nutrition , vol.44 , Issue.2 , pp. 258-264
    • Zavaleta, N.1    Figueroa, D.2    Rivera, J.3    Sanchez, J.4    Alfaro, S.5    Lonnerdal, B.6
  • 71
    • 51149102074 scopus 로고    scopus 로고
    • Human recombinant lactoferrin is synergistic with antimicrobials commonly used in neonatal practice against coagulase negative staphylococci and C. albicans causing neonatal sepsis
    • In Press
    • Venkatesh M, Liang R. Human recombinant lactoferrin is synergistic with antimicrobials commonly used in neonatal practice against coagulase negative staphylococci and C. albicans causing neonatal sepsis. J. Med. Microbiol. (2008) (In Press).
    • (2008) J. Med. Microbiol.
    • Venkatesh, M.1    Liang, R.2
  • 72
    • 3342897649 scopus 로고    scopus 로고
    • Neonatal small bowel epithelia: Enhancing anti-bacterial defense with lactoferrin and Lactobacillus GG
    • DOI 10.1023/B:BIOM.0000027706.51112.62
    • Sherman MP, Bennett SH, Hwang FF, Yu C. Neonatal small bowel epithelia: enhancing anti-bacterial defense with lactoferrin and Lactobacillus GG. Biometals 17(3), 285-289 (2004). (Pubitemid 38987151)
    • (2004) BioMetals , vol.17 , Issue.3 , pp. 285-289
    • Sherman, M.P.1    Bennett, S.H.2    Hwang, F.F.Y.3    Yu, C.4
  • 73
    • 0032846808 scopus 로고    scopus 로고
    • Elucidation of the antistaphylococcal action of lactoferrin and lysozyme
    • Leitch EC, Willcox MD. Elucidation of the antistaphylococcal action of lactoferrin and lysozyme. J. Med. Microbiol. 48(9), 867-871 (1999).
    • (1999) J. Med. Microbiol. , vol.48 , Issue.9 , pp. 867-871
    • Leitch, E.C.1    Willcox, M.D.2
  • 74
    • 0032991901 scopus 로고    scopus 로고
    • Lactoferrin increases the susceptibility of S. epidermidis biofilms to lysozyme and vancomycin
    • Leitch EC, Willcox MD. Lactoferrin increases the susceptibility of S. epidermidis biofilms to lysozyme and vancomycin. Curr. Eye Res. 19(1), 12-19 (1999).
    • (1999) Curr. Eye Res. , vol.19 , Issue.1 , pp. 12-19
    • Leitch, E.C.1    Willcox, M.D.2
  • 75
    • 0037198693 scopus 로고    scopus 로고
    • A component of innate immunity prevents bacterial biofilm development
    • Antibiofilm activity of Lf
    • Singh PK, Parsek MR, Greenberg EP, Welsh MJ. A component of innate immunity prevents bacterial biofilm development. Nature 417(6888), 552-555 (2002). • Antibiofilm activity of Lf.
    • (2002) Nature , vol.417 , Issue.6888 , pp. 552-555
    • Singh, P.K.1    Parsek, M.R.2    Greenberg, E.P.3    Welsh, M.J.4
  • 76
    • 0142169508 scopus 로고    scopus 로고
    • The effect of protein-coated contact lenses on the adhesion and viability of Gram negative bacteria
    • Williams TJ, Schneider RP, Willcox MD. The effect of protein-coated contact lenses on the adhesion and viability of Gram negative bacteria. Curr. Eye Res. 27(4), 227-235 (2003).
    • (2003) Curr. Eye Res. , vol.27 , Issue.4 , pp. 227-235
    • Williams, T.J.1    Schneider, R.P.2    Willcox, M.D.3
  • 77
    • 3342899409 scopus 로고    scopus 로고
    • Both lactoferrin and iron influence aggregation and biofilm formation in Streptococcus mutans
    • DOI 10.1023/B:BIOM.0000027704.53859.d3
    • Berlutti F, Ajello M, Bosso P et al. Both lactoferrin and iron influence aggregation and biofilm formation in Streptococcus mutans. Biometals 17(3), 271-278 (2004). (Pubitemid 38987149)
    • (2004) BioMetals , vol.17 , Issue.3 , pp. 271-278
    • Francesca, B.1    Ajello, M.2    Bosso, P.3    Morea, C.4    Andrea, P.5    Giovanni, A.6    Piera, V.7
  • 78
    • 0031836307 scopus 로고    scopus 로고
    • Evaluation of the antimicrobial effect of lactoferrin on Porphyromonas gingivalis, prevotella intermedia and prevotella nigrescens
    • DOI 10.1016/S0928-8244(98)00030-3, PII S0928824498000303
    • Aguilera O, Andres MT, Heath J, Fierro JF, Douglas CW. Evaluation of the antimicrobial effect of lactoferrin on Porphyromonas gingivalis, Prevotella intermedia and Prevotella nigrescens. FEMS Immunol. Med. Microbiol. 21(1), 29-36 (1998). (Pubitemid 28258965)
    • (1998) FEMS Immunology and Medical Microbiology , vol.21 , Issue.1 , pp. 29-36
    • Aguilera, O.1    Andres, M.T.2    Heath, J.3    Fierro, J.F.4    Douglas, C.W.I.5
  • 80
    • 0037011071 scopus 로고    scopus 로고
    • Correction of the iron overload defect in β-2-microglobulin knockout mice by lactoferrin abolishes their increased susceptibility to tuberculosis
    • DOI 10.1084/jem.20020897
    • Schaible UE, Collins HL, Priem F, Kaufmann SH. Correction of the iron overload defect in β-2-microglobulin knockout mice by lactoferrin abolishes their increased susceptibility to tuberculosis. J. Exp. Med. 196(11), 1507-1513 (2002). (Pubitemid 35424944)
    • (2002) Journal of Experimental Medicine , vol.196 , Issue.11 , pp. 1507-1513
    • Schaible, U.E.1    Collins, H.L.2    Priem, F.3    Kaufmann, S.H.E.4
  • 81
    • 0032707616 scopus 로고    scopus 로고
    • Synergistic fungistatic effects of lactoferrin in combination with antifungal drugs against clinical Candida isolates
    • Kuipers ME, de Vries HG, Eikelboom MC, Meijer DK, Swart PJ. Synergistic fungistatic effects of lactoferrin in combination with antifungal drugs against clinical Candida isolates. Antimicrob. Agents Chemother. 43(11), 2635-2641 (1999).
    • (1999) Antimicrob. Agents Chemother. , vol.43 , Issue.11 , pp. 2635-2641
    • Kuipers, M.E.1    De Vries, H.G.2    Eikelboom, M.C.3    Meijer, D.K.4    Swart, P.J.5
  • 82
    • 18344408431 scopus 로고    scopus 로고
    • Modulation of in Vitro Fungicidal Activity of Human Lactoferrin against Candida albicans by Extracellular Cation Concentration and Target Cell Metabolic Activity
    • DOI 10.1128/AAC.48.4.1242-1248.2004
    • Viejo-Diaz M, Andres MT, Fierro JF. Modulation of in vitro fungicidal activity of human lactoferrin against Candida albicans by extracellular cation concentration and target cell metabolic activity. Antimicrob. Agents Chemother. 48(4), 1242-1248 (2004). (Pubitemid 38405478)
    • (2004) Antimicrobial Agents and Chemotherapy , vol.48 , Issue.4 , pp. 1242-1248
    • Viejo-Diaz, M.1    Andres, M.T.2    Fierro, J.F.3
  • 85
    • 0030457861 scopus 로고    scopus 로고
    • Cooperative anti-Candida effects of lactoferrin or its peptides in combination with azole antifungal agents
    • Wakabayashi H, Abe S, Okutomi T, Tansho S, Kawase K, Yamaguchi H. Cooperative anti-Candida effects of lactoferrin or its peptides in combination with azole antifungal agents. Microbiol. Immunol. 40(11), 821-825 (1996). (Pubitemid 27034132)
    • (1996) Microbiology and Immunology , vol.40 , Issue.11 , pp. 821-825
    • Wakabayashi, H.1    Abe, S.2    Okutomi, T.3    Tansho, S.4    Kawase, K.5    Yamaguchi, H.6
  • 87
    • 0038397204 scopus 로고    scopus 로고
    • Lactoferricin derived from milk protein lactoferrin
    • DOI 10.2174/1381612033454829
    • Wakabayashi H, Takase M, Tomita M. Lactoferricin derived from milk protein lactoferrin. Curr. Pharm. Des. 9(16), 1277-1287 (2003). (Pubitemid 36592136)
    • (2003) Current Pharmaceutical Design , vol.9 , Issue.16 , pp. 1277-1287
    • Wakabayashi, H.1    Takase, M.2    Tomita, M.3
  • 89
    • 0029916725 scopus 로고    scopus 로고
    • Lactoferrin inhibits herpes simplex virus type 1 adsorption to Vero cells
    • DOI 10.1016/0166-3542(95)00840-3
    • Marchetti M, Longhi C, Conte MP, Pisani S, Valenti P, Seganti L. Lactoferrin inhibits herpes simplex virus type 1 adsorption to Vero cells. Antiviral Res. 29(2-3), 221-231 (1996). (Pubitemid 26135179)
    • (1996) Antiviral Research , vol.29 , Issue.2-3 , pp. 221-231
    • Marchetti, M.1    Longhi, C.2    Conte, M.P.3    Pisani, S.4    Valenti, P.5    Seganti, L.6
  • 90
    • 0031910817 scopus 로고    scopus 로고
    • Metal complexes of bovine lactoferrin inhibit in vitro replication of herpes simplex virus type 1 and 2
    • DOI 10.1023/A:1009217709851
    • Marchetti M, Pisani S, Antonini G, Valenti P, Seganti L, Orsi N. Metal complexes of bovine lactoferrin inhibit in vitro replication of herpes simplex virus type 1 and 2. Biometals 11(2), 89-94 (1998). (Pubitemid 28140327)
    • (1998) BioMetals , vol.11 , Issue.2 , pp. 89-94
    • Marchetti, M.1    Pisani, S.2    Antonini, G.3    Valenti, P.4    Seganti, L.5    Orsi, N.6
  • 92
    • 35348945790 scopus 로고    scopus 로고
    • Bovine lactoferrin prevents the entry and intercellular spread of herpes simplex virus type 1 in Green Monkey Kidney cells
    • DOI 10.1016/j.antiviral.2007.07.005, PII S0166354207003919
    • Ammendolia MG, Marchetti M, Superti F. Bovine lactoferrin prevents the entry and intercellular spread of herpes simplex virus type 1 in green monkey kidney cells. Antiviral Res. 76(3), 252-262 (2007). (Pubitemid 47600359)
    • (2007) Antiviral Research , vol.76 , Issue.3 , pp. 252-262
    • Ammendolia, M.G.1    Marchetti, M.2    Superti, F.3
  • 95
    • 0029080953 scopus 로고
    • Antiviral effects of plasma and milk proteins: Lactoferrin shows potent activity against both human immunodeficiency virus and human cytomegalovirus replication in vitro
    • Harmsen MC, Swart PJ, de Bethune MP et al. Antiviral effects of plasma and milk proteins: lactoferrin shows potent activity against both human immunodeficiency virus and human cytomegalovirus replication in vitro. J. Infect. Dis. 172(2), 380-388 (1995).
    • (1995) J. Infect. Dis. , vol.172 , Issue.2 , pp. 380-388
    • Harmsen, M.C.1    Swart, P.J.2    De Bethune, M.P.3
  • 96
    • 0031762646 scopus 로고    scopus 로고
    • Antiviral effect of bovine lactoferrin saturated with metal ions on early steps of human immunodeficiency virus type 1 infection
    • DOI 10.1016/S1357-2725(98)00066-1, PII S1357272598000661
    • Puddu P, Borghi P, Gessani S, Valenti P, Belardelli F, Seganti L. Antiviral effect of bovine lactoferrin saturated with metal ions on early steps of human immunodeficiency virus type 1 infection. Int. J. Biochem. Cell Biol. 30(9), 1055-1062 (1998). (Pubitemid 28484861)
    • (1998) International Journal of Biochemistry and Cell Biology , vol.30 , Issue.9 , pp. 1055-1063
    • Puddu, P.1    Borghi, P.2    Gessani, S.3    Valenti, P.4    Belardelli, F.5    Seganti, L.6
  • 97
    • 3342878515 scopus 로고    scopus 로고
    • The antiviral activity of the milk protein lactoferrin against the human immunodeficiency virus type 1
    • DOI 10.1023/B:BIOM.0000027707.82911.be
    • Berkhout B, Floris R, Recio I, Visser S. The antiviral activity of the milk protein lactoferrin against the human immunodeficiency virus type 1. Biometals 17(3), 291-294 (2004). (Pubitemid 38987152)
    • (2004) BioMetals , vol.17 , Issue.3 , pp. 291-294
    • Berkhout, B.1    Floris, R.2    Recio, I.3    Visser, S.4
  • 102
    • 0030740063 scopus 로고    scopus 로고
    • Hepatitis C virus envelope proteins bind lactoferrin
    • Yi M, Kaneko S, Yu DY, Murakami S. Hepatitis C virus envelope proteins bind lactoferrin. J. Virol. 71(8), 5997-6002 (1997). (Pubitemid 27304937)
    • (1997) Journal of Virology , vol.71 , Issue.8 , pp. 5997-6002
    • Yi, M.1    Kaneko, S.2    Yu, D.Y.3    Murakami, S.4
  • 103
    • 34948836847 scopus 로고    scopus 로고
    • Effect of lactoferrin in patients with chronic hepatitis C: Combination therapy with interferon and ribavirin
    • Kaito M, Iwasa M, Fujita N et al. Effect of lactoferrin in patients with chronic hepatitis C: combination therapy with interferon and ribavirin. J. Gastroenterol. Hepatol. 22(11), 1894-1897 (2007).
    • (2007) J. Gastroenterol. Hepatol. , vol.22 , Issue.11 , pp. 1894-1897
    • Kaito, M.1    Iwasa, M.2    Fujita, N.3
  • 104
    • 0242319487 scopus 로고    scopus 로고
    • Lactoferrin and surfactant protein a exhibit distinct binding specificity to F protein and differently modulate respiratory syncytial virus infection
    • DOI 10.1002/eji.200324218
    • Sano H, Nagai K, Tsutsumi H, Kuroki Y. Lactoferrin and surfactant protein A exhibit distinct binding specificity to F protein and differently modulate respiratory syncytial virus infection. Eur. J. Immunol. 33(10), 2894-2902 (2003). (Pubitemid 37337155)
    • (2003) European Journal of Immunology , vol.33 , Issue.10 , pp. 2894-2902
    • Sano, H.1    Nagai, K.2    Tsutsumi, H.3    Kuroki, Y.4
  • 105
    • 0030661831 scopus 로고    scopus 로고
    • Antirotaviral activity of milk proteins: Lactoferrin prevents rotavirus infection in the enterocyte like cell line HT-29
    • DOI 10.1007/s004300050049
    • Superti F, Ammendolia MG, Valenti P, Seganti L. Antirotaviral activity of milk proteins: lactoferrin prevents rotavirus infection in the enterocyte-like cell line HT-29. Med. Microbiol. Immunol. 186(2-3), 83-91 (1997). (Pubitemid 27477875)
    • (1997) Medical Microbiology and Immunology , vol.186 , Issue.2-3 , pp. 83-91
    • Superti, F.1    Ammendolia, M.G.2    Valenti, P.3    Seganti, L.4
  • 108
    • 0037108680 scopus 로고    scopus 로고
    • Lactoferrin inhibits enterovirus 71 infection of human embryonal rhabdomyosarcoma cells in vitro
    • DOI 10.1086/343809
    • Lin TY, Chu C, Chiu CH. Lactoferrin inhibits enterovirus 71 infection of human embryonal rhabdomyosarcoma cells in vitro. J. Infect. Dis. 186(8), 1161-1164 (2002). (Pubitemid 35177120)
    • (2002) Journal of Infectious Diseases , vol.186 , Issue.8 , pp. 1161-1164
    • Lin, T.-Y.1    Chu, C.2    Chiu, C.-H.3
  • 111
    • 0030970179 scopus 로고    scopus 로고
    • Growth inhibitory effect of bovine lactoferrin on Toxoplasma gondii tachyzoites in murine macrophages: Role of radical oxygen and inorganic nitrogen oxide in Toxoplasma growth-inhibitory activity
    • DOI 10.1016/S0304-4017(96)01069-2, PII S0304401796010692
    • Tanaka T, Omata Y, Narisawa M et al. Growth inhibitory effect of bovine lactoferrin on Toxoplasma gondii tachyzoites in murine macrophages: role of radical oxygen and inorganic nitrogen oxide in Toxoplasma growth-inhibitory activity. Vet. Parasitol. 68(1-2), 27-33 (1997). (Pubitemid 27128058)
    • (1997) Veterinary Parasitology , vol.68 , Issue.1-2 , pp. 27-33
    • Tanaka, T.1    Omata, Y.2    Narisawa, M.3    Saito, A.4    Shimazaki, K.5    Igarashi, I.6    Hirumi, H.7    Suzuki, N.8
  • 112
    • 0033789005 scopus 로고    scopus 로고
    • Inhibition of growth of Pneumocystis carinii by lactoferrins alone and in combination with pyrimethamine, clarithromycin and minocycline
    • Cirioni O, Giacometti A, Barchiesi F, Scalise G. Inhibition of growth of Pneumocystis carinii by lactoferrins alone and in combination with pyrimethamine, clarithromycin and minocycline. J. Antimicrob. Chemother. 46(4), 577-582 (2000). (Pubitemid 30793867)
    • (2000) Journal of Antimicrobial Chemotherapy , vol.46 , Issue.4 , pp. 577-582
    • Cirioni, O.1    Giacometti, A.2    Barchiesi, F.3    Scalise, G.4
  • 114
    • 0028365405 scopus 로고
    • Lactoferrin is a lipid A-binding protein
    • Appelmelk BJ, An YQ, Geerts M et al. Lactoferrin is a lipid A-binding protein. Infect. Immun. 62(6), 2628-2632 (1994).
    • (1994) Infect. Immun. , vol.62 , Issue.6 , pp. 2628-2632
    • Appelmelk, B.J.1    An, Y.Q.2    Geerts, M.3
  • 115
    • 0036129834 scopus 로고    scopus 로고
    • Lactoferrin inhibits the lipopolysaccharide-induced expression and proteoglycan-binding ability of interleukin-8 in human endothelial cells
    • Elass E, Masson M, Mazurier J, Legrand D. Lactoferrin inhibits the lipopolysaccharide-induced expression and proteoglycan-binding ability of interleukin-8 in human endothelial cells. Infect. Immun. 70(4), 1860-1866 (2002).
    • (2002) Infect. Immun. , vol.70 , Issue.4 , pp. 1860-1866
    • Elass, E.1    Masson, M.2    Mazurier, J.3    Legrand, D.4
  • 117
    • 0034834482 scopus 로고    scopus 로고
    • Biophysical characterization of lipopolysaccharide and lipid a inactivation by lactoferrin
    • DOI 10.1515/BC.2001.152
    • Brandenburg K, Jurgens G, Muller M, Fukuoka S, Koch MH. Biophysical characterization of lipopolysaccharide and lipid A inactivation by lactoferrin. Biol. Chem. 382(8), 1215-1225 (2001). (Pubitemid 32894028)
    • (2001) Biological Chemistry , vol.382 , Issue.8 , pp. 1215-1225
    • Brandenburg, K.1    Jurgens, G.2    Muller, M.3    Fukuoka, S.4    Koch, M.H.J.5
  • 118
    • 0034598975 scopus 로고    scopus 로고
    • Lactoferrin inhibits the binding of lipopolysaccharides to L-selectin and subsequent production of reactive oxygen species by neutrophils
    • DOI 10.1016/S0014-5793(00)01243-6, PII S0014579300012436
    • Baveye S, Elass E, Mazurier J, Legrand D. Lactoferrin inhibits the binding of lipopolysaccharides to L-selectin and subsequent production of reactive oxygen species by neutrophils. FEBS Lett. 469(1), 5-8 (2000). (Pubitemid 30119858)
    • (2000) FEBS Letters , vol.469 , Issue.1 , pp. 5-8
    • Baveye, S.1    Elass, E.2    Mazurier, J.3    Legrand, D.4
  • 119
    • 0034440799 scopus 로고    scopus 로고
    • Human lactoferrin interacts with soluble CD14 and inhibits expression of endothelial adhesion molecules, E-selectin and ICAM-1, induced by the CD14-lipopolysaccharide complex
    • DOI 10.1128/IAI.68.12.6519-6525.2000
    • Baveye S, Elass E, Fernig DG, Blanquart C, Mazurier J, Legrand D. Human lactoferrin interacts with soluble CD14 and inhibits expression of endothelial adhesion molecules, E-selectin and ICAM-1, induced by the CD14- lipopolysaccharide complex. Infect. Immun. 68(12), 6519-6525 (2000). (Pubitemid 32463349)
    • (2000) Infection and Immunity , vol.68 , Issue.12 , pp. 6519-6525
    • Baveye, S.1    Elass, E.2    Fernig, D.G.3    Blanquart, C.4    Mazurier, J.5    Legrand, D.6
  • 120
    • 0035451425 scopus 로고    scopus 로고
    • Lactoferrin binds CpG-containing oligonucleotides and inhibits their immunostimulatory effects on human B cells
    • Britigan BE, Lewis TS, Waldschmidt M, McCormick ML, Krieg AM. Lactoferrin binds CpG-containing oligonucleotides and inhibits their immunostimulatory effects on human B cells. J. Immunol. 167(5), 2921-2928 (2001). (Pubitemid 32768927)
    • (2001) Journal of Immunology , vol.167 , Issue.5 , pp. 2921-2928
    • Britigan, B.E.1    Lewis, T.S.2    Waldschmidt, M.3    McCormick, M.L.4    Krieg, A.M.5
  • 121
    • 0024473916 scopus 로고
    • Lactoferrin stimulated colony stimulating factor production in vitro and in vivo
    • Sawatzki G, Rich IN. Lactoferrin stimulates colony stimulating factor production in vitro and in vivo. Blood Cells 15(2), 371-385 (1989). (Pubitemid 19147925)
    • (1989) Blood Cells , vol.15 , Issue.2 , pp. 371-385
    • Sawatzki, G.1    Rich, I.N.2
  • 122
    • 0023108408 scopus 로고
    • Comparative effects in vivo of recombinant murine interleukin 3, natural murine colony-stimulating factor-1, and recombinant murine granulocyte- macrophage colony-stimulating factor on myelopoiesis in mice
    • Broxmeyer HE, Williams DE, Cooper S et al. Comparative effects in vivo of recombinant murine interleukin 3, natural murine colony-stimulating factor-1, and recombinant murine granulocyte-macrophage colony-stimulating factor on myelopoiesis in mice. J. Clin. Invest. 79(3), 721-730 (1987). (Pubitemid 17050895)
    • (1987) Journal of Clinical Investigation , vol.79 , Issue.3 , pp. 721-730
    • Broxmeyer, H.E.1    Williams, D.E.2    Cooper, S.3
  • 123
  • 125
    • 0019964764 scopus 로고
    • Modulation of classical C3 convertase of complement by tear lactoferrin
    • Kijlstra A, Jeurissen SH. Modulation of classical C3 convertase of complement by tear lactoferrin. Immunology 47(2), 263-270 (1982). (Pubitemid 12031138)
    • (1982) Immunology , vol.47 , Issue.2 , pp. 263-270
    • Kijlstra, A.1    Jeurissen, S.H.M.2
  • 126
    • 0027170227 scopus 로고
    • Activation of the classical pathway of complement by binding of bovine lactoferrin to unencapsulated Streptococcus agalactiae
    • Rainard P. Activation of the classical pathway of complement by binding of bovine lactoferrin to unencapsulated Streptococcus agalactiae. Immunology 79(4), 648-652 (1993). (Pubitemid 23246905)
    • (1993) Immunology , vol.79 , Issue.4 , pp. 648-652
    • Rainard, P.1
  • 127
    • 34250615212 scopus 로고    scopus 로고
    • Immunoregulatory function of lactoferrin in immunosuppressed and autoimmune animals
    • Zimecki M, Artym J, Chodaczek G et al. Immunoregulatory function of lactoferrin in immunosuppressed and autoimmune animals. Postepy. Hig. Med. Dosw. (Online) 61, 283-287 (2007).
    • (2007) Postepy. Hig. Med. Dosw. (Online) , vol.61 , pp. 283-287
    • Zimecki, M.1    Artym, J.2    Chodaczek, G.3
  • 128
    • 33845881154 scopus 로고    scopus 로고
    • Lactoferrin ameliorates symptoms of experimental encephalomyelitis in Lewis rats
    • DOI 10.1016/j.jneuroim.2006.10.008, PII S0165572806003936
    • Zimecki M, Kocieba M, Chodaczek G, Houszka M, Kruzel ML. Lactoferrin ameliorates symptoms of experimental encephalomyelitis in Lewis rats. J. Neuroimmunol. 182(1-2), 160-166 (2007). (Pubitemid 46026715)
    • (2007) Journal of Neuroimmunology , vol.182 , Issue.1-2 , pp. 160-166
    • Zimecki, M.1    Kocieba, M.2    Chodaczek, G.3    Houszka, M.4    Kruzel, M.L.5
  • 130
    • 0029145713 scopus 로고
    • Human lactoferrin induces phenotypic and functional changes in murine splenic B cells
    • Zimecki M, Mazurier J, Spik G, Kapp JA. Human lactoferrin induces phenotypic and functional changes in murine splenic B cells. Immunology 86(1), 122-127 (1995).
    • (1995) Immunology , vol.86 , Issue.1 , pp. 122-127
    • Zimecki, M.1    Mazurier, J.2    Spik, G.3    Kapp, J.A.4
  • 132
    • 0029845860 scopus 로고    scopus 로고
    • Lactoferrin-mediated protection of the host from murine cytomegalovirus infection by a T-cell-dependent augmentation of natural killer cell activity
    • Shimizu K, Matsuzawa H, Okada K et al. Lactoferrin-mediated protection of the host from murine cytomegalovirus infection by a T-cell-dependent augmentation of natural killer cell activity. Arch. Virol. 141(10), 1875-1889 (1996).
    • (1996) Arch. Virol. , vol.141 , Issue.10 , pp. 1875-1889
    • Shimizu, K.1    Matsuzawa, H.2    Okada, K.3
  • 133
    • 0026691005 scopus 로고
    • Modulation of natural killer and lymphokine-activated killer cell cytotoxicity by lactoferrin
    • Shau H, Kim A, Golub SH. Modulation of natural killer and lymphokine-activated killer cell cytotoxicity by lactoferrin. J. Leukoc. Biol. 51(4), 343-349 (1992).
    • (1992) J. Leukoc. Biol. , vol.51 , Issue.4 , pp. 343-349
    • Shau, H.1    Kim, A.2    Golub, S.H.3
  • 134
    • 33745955355 scopus 로고    scopus 로고
    • Oral administration of lactoferrin increases NK cell activity in mice via increased production of IL-18 and type I IFN in the small intestine
    • DOI 10.1089/jir.2006.26.489
    • Kuhara T, Yamauchi K, Tamura Y, Okamura H. Oral administration of lactoferrin increases NK cell activity in mice via increased production of IL-18 and type I IFN in the small intestine. J. Interferon Cytokine Res. 26(7), 489-499 (2006). (Pubitemid 44061089)
    • (2006) Journal of Interferon and Cytokine Research , vol.26 , Issue.7 , pp. 489-499
    • Kuhara, T.1    Yamauchi, K.2    Tamura, Y.3    Okamura, H.4
  • 136
    • 0032503991 scopus 로고    scopus 로고
    • Bovine lactoferrin stimulates the phagocytic activity of human neutrophils: Identification of its active domain
    • DOI 10.1006/cimm.1997.1246
    • Miyauchi H, Hashimoto S, Nakajima M, Shinoda I, Fukuwatari Y, Hayasawa H. Bovine lactoferrin stimulates the phagocytic activity of human neutrophils: identification of its active domain. Cell. Immunol. 187(1), 34-37 (1998). (Pubitemid 28359692)
    • (1998) Cellular Immunology , vol.187 , Issue.1 , pp. 34-37
    • Miyauchi, H.1    Hashimoto, S.-I.2    Nakajima, M.3    Shinoda, I.4    Fukuwatari, Y.5    Hayasawa, H.6
  • 137
    • 45549085804 scopus 로고    scopus 로고
    • Lactoferrin acts as an alarmin to promote the recruitment and activation of APCs and antigen-specific immune responses
    • de la Rosa G, Yang D, Tewary P, Varadhachary A, Oppenheim JJ. Lactoferrin acts as an alarmin to promote the recruitment and activation of APCs and antigen-specific immune responses. J. Immunol. 180(10), 6868-6876 (2008).
    • (2008) J. Immunol. , vol.180 , Issue.10 , pp. 6868-6876
    • De La Rosa, G.1    Yang, D.2    Tewary, P.3    Varadhachary, A.4    Oppenheim, J.J.5
  • 138
    • 48749104758 scopus 로고    scopus 로고
    • Lactoferrin, a major defense protein of innate immunity, is a novel maturation factor for human dendritic cells
    • Spadaro M, Caorsi C, Ceruti P et al. Lactoferrin, a major defense protein of innate immunity, is a novel maturation factor for human dendritic cells. FASEB J. 22(8), 2747-2757 (2008).
    • (2008) FASEB J. , vol.22 , Issue.8 , pp. 2747-2757
    • Spadaro, M.1    Caorsi, C.2    Ceruti, P.3
  • 142
    • 0036203775 scopus 로고    scopus 로고
    • Immunoregulatory activities of lactoferrin in the delayed type hypersensitivity in mice are mediated by a receptor with affinity to mannose
    • Zimecki M, Kocieba M, Kruzel M. Immunoregulatory activities of lactoferrin in the delayed type hypersensitivity in mice are mediated by a receptor with affinity to mannose. Immunobiology 205(1), 120-131 (2002). (Pubitemid 34285411)
    • (2002) Immunobiology , vol.205 , Issue.1 , pp. 120-131
    • Zimecki, M.1    Kocieba, M.2    Kruzel, M.3
  • 143
    • 33750183408 scopus 로고    scopus 로고
    • A complex of lactoferrin with monophosphoryl lipid a is an efficient adjuvant of the humoral and cellular immune response in mice
    • DOI 10.1007/s00430-006-0020-3
    • Chodaczek G, Zimecki M, Lukasiewicz J, Lugowski C. A complex of lactoferrin with monophosphoryl lipid A is an efficient adjuvant of the humoral and cellular immune response in mice. Med. Microbiol. Immunol. 195(4), 207-216 (2006). (Pubitemid 44600381)
    • (2006) Medical Microbiology and Immunology , vol.195 , Issue.4 , pp. 207-216
    • Chodaczek, G.1    Zimecki, M.2    Lukasiewicz, J.3    Lugowski, C.4


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