AAV-mediated tyrosinase gene transfer restores melanogenesis and retinal function in a model of oculo-cutaneous albinism type 1 (OCA1)

Molecular Therapy

Volumn 17, Issue 8, 2009, Pages 1347-1354

  Gargiulo, Annagiusi ^a   Bonetti, Ciro ^a   Montefusco, Sandro ^a   Neglia, Simona ^a   Di Vicino, Umberto ^a   Marrocco, Elena ^a   Corte, Michele Della ^b   Domenici, Luciano ^c,d   Auricchio, Alberto ^a   Surace, Enrico M ^a  

^a TELETHON INSTITUTE OF GENETICS AND MEDICINE TIGEM   (Italy)

^b SECOND UNIVERSITY OF NAPLES   (Italy)

^c UNIVERSITY OF L'AQUILA   (Italy)

^d CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

MELANIN; PARVOVIRUS VECTOR; TYROSINE;

ADENO ASSOCIATED VIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOROID; CONTROLLED STUDY; DRUG EFFICACY; ELECTROPHYSIOLOGY; ILLUMINATION; MELANOCYTE; MELANOGENESIS; MELANOSOME; MOUSE; NEURAL CREST; NONHUMAN; OCULOCUTANEOUS ALBINISM; PHOTORECEPTOR; PIGMENT EPITHELIUM; RETINA; VIRAL GENE DELIVERY SYSTEM; VISION;

ALBINISM, OCULOCUTANEOUS; ANIMALS; DEPENDOVIRUS; ELECTROPHYSIOLOGY; GENE THERAPY; GENETIC VECTORS; HUMANS; IRIS; MELANINS; MELANOCYTES; MICE; MICE, INBRED C57BL; MICROSCOPY, ELECTRON; MONOPHENOL MONOOXYGENASE; RETINA; RETINAL PIGMENT EPITHELIUM;

ADENO-ASSOCIATED VIRUS; MUS;

EID: 68249112028     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2009.112     Document Type: Article

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