Overexpression of the Interferon regulatory factor 4-binding protein in human colorectal cancer and its clinical significance

Cancer Epidemiology

Volumn 33, Issue 2, 2009, Pages 130-136

  Zhang, Zhujun ^a   Wang, Qingliang ^a   Li, Peng ^a   Zhou, Yu ^a   Li, Shuhui ^a   Yi, Weijing ^a   Chen, An ^a   Kong, Peiyan ^a   Hu, Chuanmin ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Antibody; Differentiation; Expression; Human colorectal cancer; IBP; Oncogenesis

Indexed keywords

INTERFERON REGULATORY FACTOR 4; MESSENGER RNA; PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; TUMOR MARKER;

ADENOMA; ADULT; AGED; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER DIAGNOSIS; CANCER STAGING; CARCINOGENESIS; CELL DIFFERENTIATION; CELL STRAIN HT29; CELL STRAIN SW480; CELL STRAIN SW620; COLORECTAL CANCER; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE SECTION; WESTERN BLOTTING;

ADENOCARCINOMA; ADENOCARCINOMA, MUCINOUS; ADENOCARCINOMA, PAPILLARY; ADENOMA; AGED; ANIMALS; BLOTTING, WESTERN; COLON; COLORECTAL NEOPLASMS; DNA-BINDING PROTEINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; IMMUNOENZYME TECHNIQUES; MALE; MIDDLE AGED; NUCLEAR PROTEINS; PROGNOSIS; RABBITS; RECOMBINANT PROTEINS; RECTUM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR CELLS, CULTURED;

EID: 68149176708     PISSN: 18777821     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canep.2009.05.004     Document Type: Article

References (31)

1. Gupta S., Lee A., Hu C., Fanzo J., Goldberg I., Cattoretti G., et al. Molecular cloning of IBP, a SWAP-70 homologous GEF, which is highly expressed in the immune system. Hum Immunol 64 (2003) 389-401
2. Grossman A., Mittrucker H.W., Nicholl J., Suzuki A., Chung S., Antonio L., et al. Cloning of human lymphocyte-specific interferon regulatory factor (hLSIRF/hIRF4) and mapping of the gene to 6p23-p25. Genomics 37 (1996) 229-233
3. Iida S., Rao P.H., Butler M., Corradini P., Boccadoro M., Klein B., et al. Deregulation of MUM1/IRF4 by chromosomal translocation in multiple myeloma. Nat Genet 17 (1997) 226-230
4. Hotfilder M., Baxendale S., Cross M.A., and Sablitzky F. Def-2, -3, -6 and -8, novel mouse genes differentially expressed in the haematopoietic system. Br J Haematol 106 (1999) 335-344
5. Tanaka Y., Bi K., Kitamura R., Hong S., Altman Y., Matsumoto A., et al. SWAP-70-like adapter of T cells, an adapter protein that regulates early TCR-initiated signaling in Th2 lineage cells. Immunity 18 (2003) 403-414
6. Gupta S., Fanzo J.C., Hu C., Cox D., Jang S.Y., Lee A.E., et al. T cell receptor engagement leads to the recruitment of IBP, a novel guanine nucleotide exchange factor, to the immunological synapse. J Biol Chem 278 (2003) 43541-43549
7. 2+/NFAT signaling. J Clin Invest 117 (2007) 2164-2175
8. Oka T., Ihara S., and Fukui Y. Cooperation of DEF6 with activated Rac in regulating cell morphology. J Biol Chem 282 (2007) 2011-2018
9. Samson T., Will C., Knoblauch A., Sharek L., von der Mark K., Burridge K., et al. Def-6, a guanine nucleotide exchange factor for Rac1, interacts with the skeletal muscle integrin chain alpha7A and influences myoblast differentiation. J Biol Chem 282 (2007) 15730-15742
10. Fanzo J.C., Yang W., Jang S.Y., Gupta S., Chen Q., Siddiq A., et al. Loss of IRF-4-binding protein leads to the spontaneous development of systemic autoimmunity. J Clin Invest 116 (2006) 703-714
11. Hu Y.X., Guo J.Y., Shen L., Chen Y., Zhang Z.C., and Zhang Y.L. Get effective polyclonal antisera in one month. Cell Res 12 (2002) 157-160
12. Shinohara M., Terada Y., Iwamatsu A., Shinohara A., Mochizuki N., Higuchi M., et al. SWAP-70 is a guanine-nucleotide-exchange factor that mediates signalling of membrane ruffling. Nature 416 (2002) 759-763
13. Zheng Y. Dbl family guanine nucleotide exchange factors. Trends Biochem Sci 26 (2001) 724-732
14. Hall A. Rho GTPases and the actin cytoskeleton. Science 279 (1998) 509-514
15. Ridley A.J. Rho family proteins: coordinating cell responses. Trends Cell Biol 11 (2001) 471-477
16. Bokoch G.M. Regulation of cell function by Rho family GTPases. Immunol Res 21 (2000) 139-148
17. Bar-Sagi D., and Hall A. Ras and Rho GTPases: a family reunion. Cell 103 (2000) 227-238
18. Pruitt K., and Der C.J. Ras and Rho regulation of the cell cycle and oncogenesis. Cancer Lett 171 (2001) 1-10
19. Jayachandran G., Sazaki J., Nishizaki M., Xu K., Girard L., Minna J.D., et al. Fragile histidine triad-mediated tumor suppression of lung cancer by targeting multiple components of the Ras/Rho GTPase molecular switch. Cancer Res 67 (2007) 10379-10388
20. Guo F., and Zheng Y. Rho family GTPases cooperate with p53 deletion to promote primary mouse embryonic fibroblast cell invasion. Oncogene 23 (2004) 5577-5585
21. Taniuchi K., Nakagawa H., Hosokawa M., Nakamura T., Eguchi H., Ohigashi H., et al. Overexpressed P-cadherin/CDH3 promotes motility of pancreatic cancer cells by interacting with p120ctn and activating rho-family GTPases. Cancer Res 65 (2005) 3092-3099
22. Vega F.M., and Ridley A.J. Rho GTPases in cancer cell biology. FEBS Lett 582 (2008) 2093-2101
23. Lin M., and van Golen K.L. Rho-regulatory proteins in breast cancer cell motility and invasion. Breast Cancer Res Treat 84 (2004) 49-60
24. Banyard J., Anand-Apte B., Symons M., and Zetter B.R. Motility and invasion are differentially modulated by Rho family GTPases. Oncogene 19 (2000) 580-591
25. Mavrakis K.J., McKinlay K.J., Jones P., and Sablitzky F. DEF6, a novel PH-DH-like domain protein, is an upstream activator of the Rho GTPases Rac1, Cdc42, and RhoA. Exp Cell Res 294 (2004) 335-344
26. De Wever O., Nguyen Q.D., Van Hoorde L., Bracke M., Bruyneel E., Gespach C., et al. Tenascin-C and SF/HGF produced by myofibroblasts in vitro provide convergent pro-invasive signals to human colon cancer cells through RhoA and Rac. FASEB J 18 (2004) 1016-1018
27. Riganti C., Doublier S., Costamagna C., Aldieri E., Pescarmona G., Ghigo D., et al. Activation of nuclear factor-kappaB pathway by simvastatin and RhoA silencing increases doxorubicin cytotoxicity in human colon cancer HT29 cells. Mol Pharmacol 74 (2008) 476-484
28. Saurin J.C., Fallavier M., Sordat B., Gevrey J.C., Chayvialle J.A., and Abello J. Bombesin stimulates invasion and migration of Isreco1 colon carcinoma cells in a Rho-dependent manner. Cancer Res 62 (2002) 4829-4835
29. Zhang Y., and Zhang B. D4-GDI, a Rho GTPase regulator, promotes breast cancer cell invasiveness. Cancer Res 66 (2006) 5592-5598
30. Wong C.M., Yam J.W., Ching Y.P., Yau T.O., Leung T.H., Jin D.Y., et al. Rho GTPase-activating protein deleted in liver cancer suppresses cell proliferation and invasion in hepatocellular carcinoma. Cancer Res 65 (2005) 8861-8868
31. Christophe D., Christophe-Hobertus C., and Pichon B. Nuclear targeting of proteins: how many different signals?. Cell Signal 12 (2000) 337-341