Fragile histidine triad-mediated tumor suppression of lung cancer by targeting multiple components of the Ras/Rho GTPase molecular switch

Cancer Research

Volumn 67, Issue 21, 2007, Pages 10379-10388

  Jayachandran, Gitanjali ^a   Sazaki, Ji Ichiro ^a   Nishizaki, Masahito ^a   Xu, Kai ^a   Girard, Luc ^b   Minna, John D ^b   Roth, Jack A ^a   Ji, Lin ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; FRAGILE HISTIDINE TRIAD PROTEIN; RAB PROTEIN; RAB11 PROTEIN; RAC PROTEIN; RAC1 PROTEIN; RAL PROTEIN; RAN PROTEIN; RAP PROTEIN; RAP1 PROTEIN; RAS PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL VIABILITY; CONTROLLED STUDY; DNA MICROARRAY; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENE SILENCING; HUMAN; HUMAN CELL; LUNG CANCER; LUNG NON SMALL CELL CANCER; METASTASIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STATISTICAL ANALYSIS; SURFACE ENHANCED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; TUMOR SUPPRESSOR GENE; TUMOR XENOGRAFT; WESTERN BLOTTING;

ACID ANHYDRIDE HYDROLASES; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; FEMALE; GENES, RAS; HUMANS; LUNG NEOPLASMS; MICE; NEOPLASM INVASIVENESS; NEOPLASM PROTEINS; PROTEIN ARRAY ANALYSIS; RHO GTP-BINDING PROTEINS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

EID: 35948968757     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-07-0677     Document Type: Article

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