-
1
-
-
0033920566
-
Protease inhibitorinduced apoptosis: Accumulation of wt p53, p21WAF1/CIP1, and induction of apoptosis are independent markers of proteasome inhibition
-
An WG, Hwang SG, Trepel JB, Blagosklonny MV. Protease inhibitorinduced apoptosis: accumulation of wt p53, p21WAF1/CIP1, and induction of apoptosis are independent markers of proteasome inhibition. Leukemia 14: 1276-1283, 2000.
-
(2000)
Leukemia
, vol.14
, pp. 1276-1283
-
-
An, W.G.1
Hwang, S.G.2
Trepel, J.B.3
Blagosklonny, M.V.4
-
2
-
-
43749098729
-
Proteasome inhibition suppresses essential immune functions of human CD4+ T cells
-
Berges C, Haberstock H, Fuchs D, Miltz M, Sadeghi M, Opelz G, Daniel V, Naujokat C. Proteasome inhibition suppresses essential immune functions of human CD4+ T cells. Immunology 124: 234-246, 2008.
-
(2008)
Immunology
, vol.124
, pp. 234-246
-
-
Berges, C.1
Haberstock, H.2
Fuchs, D.3
Miltz, M.4
Sadeghi, M.5
Opelz, G.6
Daniel, V.7
Naujokat, C.8
-
3
-
-
0032575885
-
Renal failure in multiple myeloma: Presenting features and predictors of outcome in 94 patients from a single institution
-
Blade J, Fernandez-Llama P, Bosch F, Montoliu J, Lens XM, Montoto S, Cases A, Darnell A, Rozman C, Montserrat E. Renal failure in multiple myeloma: presenting features and predictors of outcome in 94 patients from a single institution. Arch Intern Med 158: 1889-1893, 1998.
-
(1998)
Arch Intern Med
, vol.158
, pp. 1889-1893
-
-
Blade, J.1
Fernandez-Llama, P.2
Bosch, F.3
Montoliu, J.4
Lens, X.M.5
Montoto, S.6
Cases, A.7
Darnell, A.8
Rozman, C.9
Montserrat, E.10
-
4
-
-
33646421393
-
Bortezomib induces selective depletion of alloreactive T lymphocytes and decreases the production of Th1 cytokines
-
Blanco B, Perez-Simon JA, Sanchez-Abarca LI, Carvajal-Vergara X, Mateos J, Vidriales B, Lopez-Holgado N, Maiso P, Alberca M, Villaron E, Schenkein D, Pandiella A, San Miguel J. Bortezomib induces selective depletion of alloreactive T lymphocytes and decreases the production of Th1 cytokines. Blood 107: 3575-3583, 2006.
-
(2006)
Blood
, vol.107
, pp. 3575-3583
-
-
Blanco, B.1
Perez-Simon, J.A.2
Sanchez-Abarca, L.I.3
Carvajal-Vergara, X.4
Mateos, J.5
Vidriales, B.6
Lopez-Holgado, N.7
Maiso, P.8
Alberca, M.9
Villaron, E.10
Schenkein, D.11
Pandiella, A.12
San Miguel, J.13
-
5
-
-
0033083426
-
Cardioprotective effects of a novel proteasome inhibitor following ischemia and reperfusion in the isolated perfused rat heart
-
Campbell B, Adams J, Shin YK, Lefer AM. Cardioprotective effects of a novel proteasome inhibitor following ischemia and reperfusion in the isolated perfused rat heart. J Mol Cell Cardiol 31: 467-476, 1999.
-
(1999)
J Mol Cell Cardiol
, vol.31
, pp. 467-476
-
-
Campbell, B.1
Adams, J.2
Shin, Y.K.3
Lefer, A.M.4
-
6
-
-
33748369901
-
Bortezomib inhibits docetaxel-induced apoptosis via a p21-dependent mechanism in human prostate cancer cells
-
Canfield SE, Zhu K, Williams SA, McConkey DJ. Bortezomib inhibits docetaxel-induced apoptosis via a p21-dependent mechanism in human prostate cancer cells. Mol Cancer Ther 5: 2043-2050, 2006.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2043-2050
-
-
Canfield, S.E.1
Zhu, K.2
Williams, S.A.3
McConkey, D.J.4
-
7
-
-
33947201310
-
Activity and safety of bortezomib in multiple myeloma patients with advanced renal failure: A multicenter retrospective study
-
Chanan-Khan AA, Kaufman JL, Mehta J, Richardson PG, Miller KC, Lonial S, Munshi NC, Schlossman R, Tariman J, Singhal S. Activity and safety of bortezomib in multiple myeloma patients with advanced renal failure: a multicenter retrospective study. Blood 109: 2604-2606, 2007.
-
(2007)
Blood
, vol.109
, pp. 2604-2606
-
-
Chanan-Khan, A.A.1
Kaufman, J.L.2
Mehta, J.3
Richardson, P.G.4
Miller, K.C.5
Lonial, S.6
Munshi, N.C.7
Schlossman, R.8
Tariman, J.9
Singhal, S.10
-
8
-
-
4944258697
-
Targeting mitochondria to overcome conventional and bortezomib/proteasome inhibitor PS-341 resistance in multiple myeloma (MM) cells
-
Chauhan D, Li G, Podar K, Hideshima T, Mitsiades C, Schlossman R, Munshi N, Richardson P, Cotter FE, Anderson KC. Targeting mitochondria to overcome conventional and bortezomib/proteasome inhibitor PS-341 resistance in multiple myeloma (MM) cells. Blood 104: 2458-2466, 2004.
-
(2004)
Blood
, vol.104
, pp. 2458-2466
-
-
Chauhan, D.1
Li, G.2
Podar, K.3
Hideshima, T.4
Mitsiades, C.5
Schlossman, R.6
Munshi, N.7
Richardson, P.8
Cotter, F.E.9
Anderson, K.C.10
-
9
-
-
33644878412
-
Up-regulation of cell cycle regulatory genes after renal ischemia/reperfusion: Differential expression of p16, p21 and p27 cyclin-dependent kinase inhibitor genes depending on reperfusion time
-
Chkhotua AB, Abendroth D, Froeba G, Schelzig H. Up-regulation of cell cycle regulatory genes after renal ischemia/reperfusion: differential expression of p16, p21 and p27 cyclin-dependent kinase inhibitor genes depending on reperfusion time. Transpl Int 19: 72-77, 2006.
-
(2006)
Transpl Int
, vol.19
, pp. 72-77
-
-
Chkhotua, A.B.1
Abendroth, D.2
Froeba, G.3
Schelzig, H.4
-
10
-
-
0032743421
-
Inhibition of apoptosis induced by ischemia-reperfusion prevents inflammation
-
Daemen MA, van 't Veer C, Denecker G, Heemskerk VH, Wolfs TG, Clauss M, Vandenabeele P, Buurman WA. Inhibition of apoptosis induced by ischemia-reperfusion prevents inflammation. J Clin Invest 104: 541-549, 1999.
-
(1999)
J Clin Invest
, vol.104
, pp. 541-549
-
-
Daemen, M.A.1
van 't Veer, C.2
Denecker, G.3
Heemskerk, V.H.4
Wolfs, T.G.5
Clauss, M.6
Vandenabeele, P.7
Buurman, W.A.8
-
11
-
-
34147115711
-
A coordinated action of Bax, PUMA, and p53 promotes MG132-induced mitochondria activation and apoptosis in colon cancer cells
-
Ding WX, Ni HM, Chen X, Yu J, Zhang L, Yin XM. A coordinated action of Bax, PUMA, and p53 promotes MG132-induced mitochondria activation and apoptosis in colon cancer cells. Mol Cancer Ther 6: 1062-1069, 2007.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 1062-1069
-
-
Ding, W.X.1
Ni, H.M.2
Chen, X.3
Yu, J.4
Zhang, L.5
Yin, X.M.6
-
12
-
-
0037569481
-
Proteasome inhibition: A new anti-inflammatory strategy
-
Elliott PJ, Zollner TM, Boehncke WH. Proteasome inhibition: a new anti-inflammatory strategy. J Mol Med 81: 235-245, 2003.
-
(2003)
J Mol Med
, vol.81
, pp. 235-245
-
-
Elliott, P.J.1
Zollner, T.M.2
Boehncke, W.H.3
-
13
-
-
26844518105
-
The subunit structure and dynamics of the 20S proteasome in chicken skeletal muscle
-
Hayter JR, Doherty MK, Whitehead C, McCormack H, Gaskell SJ, Beynon RJ. The subunit structure and dynamics of the 20S proteasome in chicken skeletal muscle. Mol Cell Proteomics 4: 1370-1381, 2005.
-
(2005)
Mol Cell Proteomics
, vol.4
, pp. 1370-1381
-
-
Hayter, J.R.1
Doherty, M.K.2
Whitehead, C.3
McCormack, H.4
Gaskell, S.J.5
Beynon, R.J.6
-
14
-
-
34548550283
-
Tissue distribution and depletion kinetics of bortezomib and bortezomib-related radioactivity in male rats after single and repeated intravenous injection of 14 C-bortezomib
-
Hemeryck A, Geerts R, Monbaliu J, Hassler S, Verhaeghe T, Diels L, Verluyten W, van Beijsterveldt L, Mamidi RN, Janssen C, De Coster R. Tissue distribution and depletion kinetics of bortezomib and bortezomib-related radioactivity in male rats after single and repeated intravenous injection of 14 C-bortezomib. Cancer Chemother Pharmacol 60: 777-787, 2007.
-
(2007)
Cancer Chemother Pharmacol
, vol.60
, pp. 777-787
-
-
Hemeryck, A.1
Geerts, R.2
Monbaliu, J.3
Hassler, S.4
Verhaeghe, T.5
Diels, L.6
Verluyten, W.7
van Beijsterveldt, L.8
Mamidi, R.N.9
Janssen, C.10
De Coster, R.11
-
15
-
-
0035300479
-
The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells
-
Hideshima T, Richardson P, Chauhan D, Palombella VJ, Elliott PJ, Adams J, Anderson KC. The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells. Cancer Res 61: 3071-3076, 2001.
-
(2001)
Cancer Res
, vol.61
, pp. 3071-3076
-
-
Hideshima, T.1
Richardson, P.2
Chauhan, D.3
Palombella, V.J.4
Elliott, P.J.5
Adams, J.6
Anderson, K.C.7
-
16
-
-
33846862269
-
p21 and mTERT are novel markers for determining different ischemic time periods in renal ischemia-reperfusion injury
-
Hochegger K, Koppelstaetter C, Tagwerker A, Huber JM, Heininger D, Mayer G, Rosenkranz AR. p21 and mTERT are novel markers for determining different ischemic time periods in renal ischemia-reperfusion injury. Am J Physiol Renal Physiol 292: F762-F768, 2007.
-
(2007)
Am J Physiol Renal Physiol
, vol.292
-
-
Hochegger, K.1
Koppelstaetter, C.2
Tagwerker, A.3
Huber, J.M.4
Heininger, D.5
Mayer, G.6
Rosenkranz, A.R.7
-
17
-
-
34548635807
-
Role of α /β and γ /δ T cells in renal ischemia reperfusion injury
-
Hochegger K, Schatz T, Eller P, Tagwerker A, Heininger D, Mayer G, Rosenkranz AR. Role of α /β and γ /δ T cells in renal ischemia reperfusion injury. Am J Physiol Renal Physiol 293: F741-F747, 2007.
-
(2007)
Am J Physiol Renal Physiol
, vol.293
-
-
Hochegger, K.1
Schatz, T.2
Eller, P.3
Tagwerker, A.4
Heininger, D.5
Mayer, G.6
Rosenkranz, A.R.7
-
18
-
-
41549114524
-
Proteasome inhibition 1 h following ischemia protects GRK2 and prevents malignant ventricular tachyarrhythmias and SCD in a model of myocardial infarction
-
Huang S, Patterson E, Yu X, Garrett MW, De Aos I, Kem DC. Proteasome inhibition 1 h following ischemia protects GRK2 and prevents malignant ventricular tachyarrhythmias and SCD in a model of myocardial infarction. Am J Physiol Heart Circ Physiol 294: H1298-H1303, 2008.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.294
-
-
Huang, S.1
Patterson, E.2
Yu, X.3
Garrett, M.W.4
De Aos, I.5
Kem, D.C.6
-
19
-
-
0029100853
-
Acute renal failure: Prevailing challenges and prospects for the future
-
Humes HD. Acute renal failure: prevailing challenges and prospects for the future. Kidney Int Suppl 50: S26-S32, 1995.
-
(1995)
Kidney Int Suppl
, vol.50
-
-
Humes, H.D.1
-
20
-
-
0034927443
-
Preventive effect of lactacystin, a selective proteasome inhibitor, on ischemic acute renal failure in rats
-
Itoh M, Takaoka M, Shibata A, Ohkita M, Matsumura Y. Preventive effect of lactacystin, a selective proteasome inhibitor, on ischemic acute renal failure in rats. J Pharmacol Exp Ther 298: 501-507, 2001.
-
(2001)
J Pharmacol Exp Ther
, vol.298
, pp. 501-507
-
-
Itoh, M.1
Takaoka, M.2
Shibata, A.3
Ohkita, M.4
Matsumura, Y.5
-
21
-
-
5644250621
-
A phase 2 study of two doses of bortezomib in relapsed or refractory myeloma
-
Jagannath S, Barlogie B, Berenson J, Siegel D, Irwin D, Richardson PG, Niesvizky R, Alexanian R, Limentani SA, Alsina M, Adams J, Kauffman M, Esseltine DL, Schenkein DP, Anderson KC. A phase 2 study of two doses of bortezomib in relapsed or refractory myeloma. Br J Haematol 127: 165-172, 2004.
-
(2004)
Br J Haematol
, vol.127
, pp. 165-172
-
-
Jagannath, S.1
Barlogie, B.2
Berenson, J.3
Siegel, D.4
Irwin, D.5
Richardson, P.G.6
Niesvizky, R.7
Alexanian, R.8
Limentani, S.A.9
Alsina, M.10
Adams, J.11
Kauffman, M.12
Esseltine, D.L.13
Schenkein, D.P.14
Anderson, K.C.15
-
22
-
-
20044381304
-
Bortezomib in recurrent and/or refractory multiple myeloma. Initial clinical experience in patients with impaired renal function
-
Jagannath S, Barlogie B, Berenson JR, Singhal S, Alexanian R, Srkalovic G, Orlowski RZ, Richardson PG, Anderson J, Nix D, Esseltine DL, Anderson KC. Bortezomib in recurrent and/or refractory multiple myeloma. Initial clinical experience in patients with impaired renal function. Cancer 103: 1195-1200, 2005.
-
(2005)
Cancer
, vol.103
, pp. 1195-1200
-
-
Jagannath, S.1
Barlogie, B.2
Berenson, J.R.3
Singhal, S.4
Alexanian, R.5
Srkalovic, G.6
Orlowski, R.Z.7
Richardson, P.G.8
Anderson, J.9
Nix, D.10
Esseltine, D.L.11
Anderson, K.C.12
-
23
-
-
0037218760
-
P53 mediates the apoptotic response to GTP depletion after renal ischemia-reperfusion: Protective role of a p53 inhibitor
-
Kelly KJ, Plotkin Z, Vulgamott SL, Dagher PC. P53 mediates the apoptotic response to GTP depletion after renal ischemia-reperfusion: protective role of a p53 inhibitor. J Am Soc Nephrol 14: 128-138, 2003.
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 128-138
-
-
Kelly, K.J.1
Plotkin, Z.2
Vulgamott, S.L.3
Dagher, P.C.4
-
24
-
-
0028135393
-
Renal function in newly diagnosed multiple myeloma-a demographic study of 1353 patients. The Nordic Myeloma Study Group
-
Knudsen LM, Hippe E, Hjorth M, Holmberg E, Westin J. Renal function in newly diagnosed multiple myeloma-a demographic study of 1353 patients. The Nordic Myeloma Study Group. Eur J Haematol 53: 207-212, 1994.
-
(1994)
Eur J Haematol
, vol.53
, pp. 207-212
-
-
Knudsen, L.M.1
Hippe, E.2
Hjorth, M.3
Holmberg, E.4
Westin, J.5
-
25
-
-
0034789534
-
Rapamycin impairs recovery from acute renal failure: Role of cell-cycle arrest and apoptosis of tubular cells
-
Lieberthal W, Fuhro R, Andry CC, Rennke H, Abernathy VE, Koh JS, Valeri R, Levine JS. Rapamycin impairs recovery from acute renal failure: role of cell-cycle arrest and apoptosis of tubular cells. Am J Physiol Renal Physiol 281: F693-F706, 2001.
-
(2001)
Am J Physiol Renal Physiol
, vol.281
-
-
Lieberthal, W.1
Fuhro, R.2
Andry, C.C.3
Rennke, H.4
Abernathy, V.E.5
Koh, J.S.6
Valeri, R.7
Levine, J.S.8
-
26
-
-
0036677061
-
Tissue-specific regulation of Fas/APO-1/CD95 expression by p53
-
Lin P, Bush JA, Cheung KJ Jr, Li G. Tissue-specific regulation of Fas/APO-1/CD95 expression by p53. Int J Oncol 21: 261-264, 2002.
-
(2002)
Int J Oncol
, vol.21
, pp. 261-264
-
-
Lin, P.1
Bush, J.A.2
Cheung Jr, K.J.3
Li, G.4
-
27
-
-
45349092269
-
Proteasome inhibitor Bortezomib induces cell cycle arrest and apoptosis in cell lines derived from Ewing's sarcoma family of tumors and synergizes with TRAIL
-
Lu G, Punj V, Chaudhary PM. Proteasome inhibitor Bortezomib induces cell cycle arrest and apoptosis in cell lines derived from Ewing's sarcoma family of tumors and synergizes with TRAIL. Cancer Biol Ther 7: 603-608, 2008.
-
(2008)
Cancer Biol Ther
, vol.7
, pp. 603-608
-
-
Lu, G.1
Punj, V.2
Chaudhary, P.M.3
-
28
-
-
27244460815
-
Proteasome inhibition and its clinical prospects in the treatment of hematologic and solid malignancies
-
Ludwig H, Khayat D, Giaccone G, Facon T. Proteasome inhibition and its clinical prospects in the treatment of hematologic and solid malignancies. Cancer 104: 1794-1807, 2005.
-
(2005)
Cancer
, vol.104
, pp. 1794-1807
-
-
Ludwig, H.1
Khayat, D.2
Giaccone, G.3
Facon, T.4
-
29
-
-
0038666511
-
Sirolimus prolongs recovery from delayed graft function after cadaveric renal transplantation
-
McTaggart RA, Gottlieb D, Brooks J, Bacchetti P, Roberts JP, Tomlanovich S, Feng S. Sirolimus prolongs recovery from delayed graft function after cadaveric renal transplantation. Am J Transplant 3: 416-423, 2003.
-
(2003)
Am J Transplant
, vol.3
, pp. 416-423
-
-
McTaggart, R.A.1
Gottlieb, D.2
Brooks, J.3
Bacchetti, P.4
Roberts, J.P.5
Tomlanovich, S.6
Feng, S.7
-
30
-
-
0035176512
-
Positive effect of the induction of p21WAF1/CIP1 on the course of ischemic acute renal failure
-
Megyesi J, Andrade L, Vieira JM Jr, Safirstein RL, Price PM. Positive effect of the induction of p21WAF1/CIP1 on the course of ischemic acute renal failure. Kidney Int 60: 2164-2172, 2001.
-
(2001)
Kidney Int
, vol.60
, pp. 2164-2172
-
-
Megyesi, J.1
Andrade, L.2
Vieira Jr, J.M.3
Safirstein, R.L.4
Price, P.M.5
-
32
-
-
46749088320
-
The proteasome inhibitor bortezomib depletes plasma cells and protects mice with lupus-like disease from nephritis
-
Neubert K, Meister S, Moser K, Weisel F, Maseda D, Amann K, Wiethe C, Winkler TH, Kalden JR, Manz RA, Voll RE. The proteasome inhibitor bortezomib depletes plasma cells and protects mice with lupus-like disease from nephritis. Nat Med 14: 748-755, 2008.
-
(2008)
Nat Med
, vol.14
, pp. 748-755
-
-
Neubert, K.1
Meister, S.2
Moser, K.3
Weisel, F.4
Maseda, D.5
Amann, K.6
Wiethe, C.7
Winkler, T.H.8
Kalden, J.R.9
Manz, R.A.10
Voll, R.E.11
-
33
-
-
33745945915
-
Bortezomib-dexamethasone combination in a patient with refractory multiple myeloma and impaired renal function
-
Nozza A, Siracusano L, Armando S. Bortezomib-dexamethasone combination in a patient with refractory multiple myeloma and impaired renal function. Clin Ther 28: 953-959, 2006.
-
(2006)
Clin Ther
, vol.28
, pp. 953-959
-
-
Nozza, A.1
Siracusano, L.2
Armando, S.3
-
34
-
-
37349119748
-
Proteasome inhibitor attenuates skeletal muscle reperfusion injury by blocking the pathway of nuclear factor-kappaB activation
-
Park JW, Qi WN, Cai Y, Urbaniak JR, Chen LE. Proteasome inhibitor attenuates skeletal muscle reperfusion injury by blocking the pathway of nuclear factor-kappaB activation. Plast Reconstr Surg 120: 1808-1818, 2007.
-
(2007)
Plast Reconstr Surg
, vol.120
, pp. 1808-1818
-
-
Park, J.W.1
Qi, W.N.2
Cai, Y.3
Urbaniak, J.R.4
Chen, L.E.5
-
35
-
-
0033918122
-
Proteasome inhibitor PS519 reduces infarction and attenuates leukocyte infiltration in a rat model of focal cerebral ischemia
-
Phillips JB, Williams AJ, Adams J, Elliott PJ, Tortella FC. Proteasome inhibitor PS519 reduces infarction and attenuates leukocyte infiltration in a rat model of focal cerebral ischemia. Stroke 31: 1686 -1693, 2000.
-
(2000)
Stroke
, vol.31
, pp. 1686-1693
-
-
Phillips, J.B.1
Williams, A.J.2
Adams, J.3
Elliott, P.J.4
Tortella, F.C.5
-
36
-
-
0037370653
-
Proteasome inhibition ablates activation of NF-κB in myocardial reperfusion and reduces reperfusion injury
-
Pye J, Ardeshirpour F, McCain A, Bellinger DA, Merricks E, Adams J, Elliott PJ, Pien C, Fischer TH, Baldwin AS Jr, Nichols TC. Proteasome inhibition ablates activation of NF-κB in myocardial reperfusion and reduces reperfusion injury. Am J Physiol Heart Circ Physiol 284: H919-H926, 2003.
-
(2003)
Am J Physiol Heart Circ Physiol
, vol.284
-
-
Pye, J.1
Ardeshirpour, F.2
McCain, A.3
Bellinger, D.A.4
Merricks, E.5
Adams, J.6
Elliott, P.J.7
Pien, C.8
Fischer, T.H.9
Baldwin Jr, A.S.10
Nichols, T.C.11
-
37
-
-
0033826104
-
Pathophysiological role of T lymphocytes in renal ischemia-reperfusion injury in mice
-
Rabb H, Daniels F, O'Donnell M, Haq M, Saba SR, Keane W, Tang WW. Pathophysiological role of T lymphocytes in renal ischemia-reperfusion injury in mice. Am J Physiol Renal Physiol 279: F525-F531, 2000.
-
(2000)
Am J Physiol Renal Physiol
, vol.279
-
-
Rabb, H.1
Daniels, F.2
O'Donnell, M.3
Haq, M.4
Saba, S.R.5
Keane, W.6
Tang, W.W.7
-
38
-
-
1642480062
-
Salicylate reduces cisplatin nephrotoxicity by inhibition of tumor necrosis factor-α
-
Ramesh G, Reeves WB. Salicylate reduces cisplatin nephrotoxicity by inhibition of tumor necrosis factor-α. Kidney Int 65: 490-499, 2004.
-
(2004)
Kidney Int
, vol.65
, pp. 490-499
-
-
Ramesh, G.1
Reeves, W.B.2
-
39
-
-
0037973279
-
A phase 2 study of bortezomib in relapsed, refractory myeloma
-
Richardson PG, Barlogie B, Berenson J, Singhal S, Jagannath S, Irwin D, Rajkumar SV, Srkalovic G, Alsina M, Alexanian R, Siegel D, Orlowski RZ, Kuter D, Limentani SA, Lee S, Hideshima T, Esseltine DL, Kauffman M, Adams J, Schenkein DP, Anderson KC. A phase 2 study of bortezomib in relapsed, refractory myeloma. N Engl J Med 348: 2609-2617, 2003.
-
(2003)
N Engl J Med
, vol.348
, pp. 2609-2617
-
-
Richardson, P.G.1
Barlogie, B.2
Berenson, J.3
Singhal, S.4
Jagannath, S.5
Irwin, D.6
Rajkumar, S.V.7
Srkalovic, G.8
Alsina, M.9
Alexanian, R.10
Siegel, D.11
Orlowski, R.Z.12
Kuter, D.13
Limentani, S.A.14
Lee, S.15
Hideshima, T.16
Esseltine, D.L.17
Kauffman, M.18
Adams, J.19
Schenkein, D.P.20
Anderson, K.C.21
more..
-
40
-
-
37349000946
-
Targeting apoptosis in solid tumors: The role of bortezomib from preclinical to clinical evidence
-
Russo A, Fratto ME, Bazan V, Schiro V, Agnese V, Cicero G, Vincenzi B, Tonini G, Santini D. Targeting apoptosis in solid tumors: the role of bortezomib from preclinical to clinical evidence. Expert Opin Ther Targets 11: 1571-1586, 2007.
-
(2007)
Expert Opin Ther Targets
, vol.11
, pp. 1571-1586
-
-
Russo, A.1
Fratto, M.E.2
Bazan, V.3
Schiro, V.4
Agnese, V.5
Cicero, G.6
Vincenzi, B.7
Tonini, G.8
Santini, D.9
-
41
-
-
0348226836
-
Role of apoptosis in hypoxic/ischemic damage in the kidney
-
Saikumar P, Venkatachalam MA. Role of apoptosis in hypoxic/ischemic damage in the kidney. Semin Nephrol 23: 511-521, 2003.
-
(2003)
Semin Nephrol
, vol.23
, pp. 511-521
-
-
Saikumar, P.1
Venkatachalam, M.A.2
-
42
-
-
0026551591
-
Morphologic, biochemical, and molecular evidence of apoptosis during the reperfusion phase after brief periods of renal ischemia
-
Schumer M, Colombel MC, Sawczuk IS, Gobe G, Connor J, O'Toole KM, Olsson CA, Wise GJ, Buttyan R. Morphologic, biochemical, and molecular evidence of apoptosis during the reperfusion phase after brief periods of renal ischemia. Am J Pathol 140: 831-838, 1992.
-
(1992)
Am J Pathol
, vol.140
, pp. 831-838
-
-
Schumer, M.1
Colombel, M.C.2
Sawczuk, I.S.3
Gobe, G.4
Connor, J.5
O'Toole, K.M.6
Olsson, C.A.7
Wise, G.J.8
Buttyan, R.9
-
43
-
-
0037378763
-
Delayed graft function and cast nephropathy associated with tacrolimus plus rapamycin use
-
Smith KD, Wrenshall LE, Nicosia RF, Pichler R, Marsh CL, Alpers CE, Polissar N, Davis CL. Delayed graft function and cast nephropathy associated with tacrolimus plus rapamycin use. J Am Soc Nephrol 14: 1037-1045, 2003.
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 1037-1045
-
-
Smith, K.D.1
Wrenshall, L.E.2
Nicosia, R.F.3
Pichler, R.4
Marsh, C.L.5
Alpers, C.E.6
Polissar, N.7
Davis, C.L.8
-
44
-
-
34250708935
-
Bortezomib significantly impairs the immunostimulatory capacity of human myeloid blood dendritic cells
-
Straube C, Wehner R, Wendisch M, Bornhauser M, Bachmann M, Rieber EP, Schmitz M. Bortezomib significantly impairs the immunostimulatory capacity of human myeloid blood dendritic cells. Leukemia 21: 1464-1471, 2007.
-
(2007)
Leukemia
, vol.21
, pp. 1464-1471
-
-
Straube, C.1
Wehner, R.2
Wendisch, M.3
Bornhauser, M.4
Bachmann, M.5
Rieber, E.P.6
Schmitz, M.7
-
45
-
-
0033734939
-
Proteasome inhibition attenuates renal endothelin-1 production and the development of ischemic acute renal failure in rats
-
Takaoka M, Itoh M, Kohyama S, Shibata A, Ohkita M, Matsumura Y. Proteasome inhibition attenuates renal endothelin-1 production and the development of ischemic acute renal failure in rats. J Cardiovasc Pharmacol 36: S225-S227, 2000.
-
(2000)
J Cardiovasc Pharmacol
, vol.36
-
-
Takaoka, M.1
Itoh, M.2
Kohyama, S.3
Shibata, A.4
Ohkita, M.5
Matsumura, Y.6
-
46
-
-
0030804113
-
Effects of initial ischemia/reperfusion injury on the transplanted kidney
-
Tilney NL, Guttmann RD. Effects of initial ischemia/reperfusion injury on the transplanted kidney. Transplantation 64: 945-947, 1997.
-
(1997)
Transplantation
, vol.64
, pp. 945-947
-
-
Tilney, N.L.1
Guttmann, R.D.2
-
47
-
-
35348817955
-
Proteasome inhibitor, bortezomib, for myeloma and lymphoma
-
Tobinai K. Proteasome inhibitor, bortezomib, for myeloma and lymphoma. Int J Clin Oncol 12: 318-326, 2007.
-
(2007)
Int J Clin Oncol
, vol.12
, pp. 318-326
-
-
Tobinai, K.1
-
48
-
-
12444281834
-
Molecular mechanisms of acute renal failure following ischemia/reperfusion
-
Versteilen AM, Di Maggio F, Leemreis JR, Groeneveld AB, Musters RJ, Sipkema P. Molecular mechanisms of acute renal failure following ischemia/reperfusion. Int J Artif Organs 27: 1019-1029, 2004.
-
(2004)
Int J Artif Organs
, vol.27
, pp. 1019-1029
-
-
Versteilen, A.M.1
Di Maggio, F.2
Leemreis, J.R.3
Groeneveld, A.B.4
Musters, R.J.5
Sipkema, P.6
-
49
-
-
33646799132
-
Strategies for therapeutic targeting of the p53 pathway in cancer
-
Wiman KG. Strategies for therapeutic targeting of the p53 pathway in cancer. Cell Death Differ 13: 921-926, 2006.
-
(2006)
Cell Death Differ
, vol.13
, pp. 921-926
-
-
Wiman, K.G.1
-
50
-
-
2542565185
-
Ubiquitin-proteasome system and proteasome inhibition: New strategies in stroke therapy
-
Wojcik C, Di Napoli M. Ubiquitin-proteasome system and proteasome inhibition: new strategies in stroke therapy. Stroke 35: 1506-1518, 2004.
-
(2004)
Stroke
, vol.35
, pp. 1506-1518
-
-
Wojcik, C.1
Di Napoli, M.2
-
51
-
-
0031253977
-
-
Wu GS, Burns TF, McDonald ER 3rd, Jiang W, Meng R, Krantz ID, Kao G, Gan DD, Zhou JY, Muschel R, Hamilton SR, Spinner NB, Markowitz S, Wu G, el-Deiry WS. KILLER/DR5 is a DNA damageinducible p53-regulated death receptor gene. Nat Genet 17: 141-143, 1997.
-
Wu GS, Burns TF, McDonald ER 3rd, Jiang W, Meng R, Krantz ID, Kao G, Gan DD, Zhou JY, Muschel R, Hamilton SR, Spinner NB, Markowitz S, Wu G, el-Deiry WS. KILLER/DR5 is a DNA damageinducible p53-regulated death receptor gene. Nat Genet 17: 141-143, 1997.
-
-
-
-
52
-
-
0033776898
-
Identification and kinetics of leukocytes after severe ischaemia/reperfusion renal injury
-
Ysebaert DK, De Greef KE, Vercauteren SR, Ghielli M, Verpooten GA, Eyskens EJ, De Broe ME. Identification and kinetics of leukocytes after severe ischaemia/reperfusion renal injury. Nephrol Dial Transplant 15: 1562-1574, 2000.
-
(2000)
Nephrol Dial Transplant
, vol.15
, pp. 1562-1574
-
-
Ysebaert, D.K.1
De Greef, K.E.2
Vercauteren, S.R.3
Ghielli, M.4
Verpooten, G.A.5
Eyskens, E.J.6
De Broe, M.E.7
|