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Volumn 120, Issue 7, 2007, Pages 1808-1818

Proteasome inhibitor attenuates skeletal muscle reperfusion injury by blocking the pathway of nuclear factor-κB activation

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROTYROSINE; BORTEZOMIB; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERCELLULAR ADHESION MOLECULE 1; PHOSPHATE BUFFERED SALINE; PROTEASOME INHIBITOR; SYNAPTOTAGMIN I;

EID: 37349119748     PISSN: 00321052     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.prs.0000287245.17319.57     Document Type: Article
Times cited : (21)

References (53)
  • 1
    • 0030834405 scopus 로고    scopus 로고
    • Molecular mechanisms of anoxia/reoxygenation-induced neutrophil adherence to cultured endothelial cells
    • Ichikawa, H., Flores, S., Kvietys, P. R., et al. Molecular mechanisms of anoxia/reoxygenation-induced neutrophil adherence to cultured endothelial cells. Circ. Res. 81: 922, 1997.
    • (1997) Circ. Res , vol.81 , pp. 922
    • Ichikawa, H.1    Flores, S.2    Kvietys, P.R.3
  • 2
    • 0026763966 scopus 로고
    • Anoxia/ reoxygenation-induced neutrophil adherence to cultured endothelial cells
    • Yoshida, N., Granger, D. N., Anderson, D. C., et al. Anoxia/ reoxygenation-induced neutrophil adherence to cultured endothelial cells. Am. J. Physiol. 262: H1891, 1992.
    • (1992) Am. J. Physiol , vol.262
    • Yoshida, N.1    Granger, D.N.2    Anderson, D.C.3
  • 3
    • 0035031097 scopus 로고    scopus 로고
    • Targeted disruption of the nitric oxide synthase 2 gene protects against ischaemia/reperfusion injury to skeletal muscle
    • Barker, J. E., Knight, K. R., Romeo, R., et al. Targeted disruption of the nitric oxide synthase 2 gene protects against ischaemia/reperfusion injury to skeletal muscle. J. Pathol. 194: 109, 2001.
    • (2001) J. Pathol , vol.194 , pp. 109
    • Barker, J.E.1    Knight, K.R.2    Romeo, R.3
  • 4
    • 4644230507 scopus 로고    scopus 로고
    • Reperfusion injury in skeletal muscle is reduced in inducible nitric oxide synthase knockout mice
    • Qi, W. N., Chen, L. E., Zhang, L., et al. Reperfusion injury in skeletal muscle is reduced in inducible nitric oxide synthase knockout mice. J. Appl. Physiol. 97: 1323, 2004.
    • (2004) J. Appl. Physiol , vol.97 , pp. 1323
    • Qi, W.N.1    Chen, L.E.2    Zhang, L.3
  • 5
    • 3342969328 scopus 로고    scopus 로고
    • NF-kappaB p65 involves in reperfusion injury and iNOS gene regulation in skeletal muscle
    • Qi, W. N., Chaiyakit, P., Cai, Y., et al. NF-kappaB p65 involves in reperfusion injury and iNOS gene regulation in skeletal muscle. Microsurgery 24: 316, 2004.
    • (2004) Microsurgery , vol.24 , pp. 316
    • Qi, W.N.1    Chaiyakit, P.2    Cai, Y.3
  • 6
    • 3343019020 scopus 로고    scopus 로고
    • Inhibition of iNOS with 1400W improves contractile function and alters nos gene and protein expression in reperfused skeletal muscle
    • Patel, P., Qi, W. N., Allen, D. M., et al. Inhibition of iNOS with 1400W improves contractile function and alters nos gene and protein expression in reperfused skeletal muscle. Microsurgery 24: 324, 2004.
    • (2004) Microsurgery , vol.24 , pp. 324
    • Patel, P.1    Qi, W.N.2    Allen, D.M.3
  • 7
    • 0034837291 scopus 로고    scopus 로고
    • Gene and protein expressions of nitric oxide synthases in ischemia-reperfused peripheral nerve of the rat
    • Qi, W. N., Yan, Z. Q., Whang, P. G., et al. Gene and protein expressions of nitric oxide synthases in ischemia-reperfused peripheral nerve of the rat. Am. J. Physiol. 281: C849, 2001.
    • (2001) Am. J. Physiol , vol.281
    • Qi, W.N.1    Yan, Z.Q.2    Whang, P.G.3
  • 8
    • 0037378522 scopus 로고    scopus 로고
    • Reperfusion injury is reduced in skeletal muscle by inhibition of inducible nitric oxide synthase
    • Zhang, L., Looney, C. G., Qi, W. N., et al. Reperfusion injury is reduced in skeletal muscle by inhibition of inducible nitric oxide synthase. J. Appl. Physiol. 94: 1473, 2003.
    • (2003) J. Appl. Physiol , vol.94 , pp. 1473
    • Zhang, L.1    Looney, C.G.2    Qi, W.N.3
  • 9
    • 0030763034 scopus 로고    scopus 로고
    • The leukocyte cell adhesion cascade and its role in myocardial ischemiareperfusion injury
    • Gumina, R. J., Newman, P. J., Kenny, D., et al. The leukocyte cell adhesion cascade and its role in myocardial ischemiareperfusion injury. Basic Res. Cardiol. 92: 201, 1997.
    • (1997) Basic Res. Cardiol , vol.92 , pp. 201
    • Gumina, R.J.1    Newman, P.J.2    Kenny, D.3
  • 10
    • 0036714543 scopus 로고    scopus 로고
    • Quantitative real-time RT-PCR analysis of inflammatory gene expression associated with ischemia-reperfusion brain injury
    • Berti, R., Williams, A. J., Moffett, J. R., et al. Quantitative real-time RT-PCR analysis of inflammatory gene expression associated with ischemia-reperfusion brain injury. J. Cereb. Blood Flow Metab. 22: 1068, 2002.
    • (2002) J. Cereb. Blood Flow Metab , vol.22 , pp. 1068
    • Berti, R.1    Williams, A.J.2    Moffett, J.R.3
  • 11
    • 0028221259 scopus 로고
    • P-selectin and ICAM-1-dependent adherence reactions: Role in the genesis of postischemic no-reflow
    • Jerome, S. N., Dore, M., Paulson, J. C., et al. P-selectin and ICAM-1-dependent adherence reactions: Role in the genesis of postischemic no-reflow. Am. J. Physiol. 266: H1316, 1994.
    • (1994) Am. J. Physiol , vol.266
    • Jerome, S.N.1    Dore, M.2    Paulson, J.C.3
  • 12
    • 0033083426 scopus 로고    scopus 로고
    • Cardioprotective effects of a novel proteasome inhibitor following ischemia and reperfusion in the isolated perfused rat heart
    • Campbell, B., Adams, J., Shin, Y. K., et al. Cardioprotective effects of a novel proteasome inhibitor following ischemia and reperfusion in the isolated perfused rat heart. J. Mol. Cell. Cardiol. 31: 467, 1999.
    • (1999) J. Mol. Cell. Cardiol , vol.31 , pp. 467
    • Campbell, B.1    Adams, J.2    Shin, Y.K.3
  • 13
    • 0034656846 scopus 로고    scopus 로고
    • Cerebral ischemia: Gene activation, neuronal injury, and the protective role of antioxidants
    • Clemens, J. A. Cerebral ischemia: Gene activation, neuronal injury, and the protective role of antioxidants. Free Radic. Biol. Med. 28: 1526, 2000.
    • (2000) Free Radic. Biol. Med , vol.28 , pp. 1526
    • Clemens, J.A.1
  • 14
    • 0034108338 scopus 로고    scopus 로고
    • Early renal ischemia, with or without reperfusion, activates NFkappaB and increases TNF-alpha bioactivity in the kidney
    • Donnahoo, K. K., Meldrum, D. R., Shenkar, R., et al. Early renal ischemia, with or without reperfusion, activates NFkappaB and increases TNF-alpha bioactivity in the kidney. J. Urol. 163: 1328, 2000.
    • (2000) J. Urol , vol.163 , pp. 1328
    • Donnahoo, K.K.1    Meldrum, D.R.2    Shenkar, R.3
  • 15
    • 0345549528 scopus 로고    scopus 로고
    • Effects of NF-kappa B inhibition on mesenteric ischemia-reperfusion injury
    • Zou, L., Attuwaybi, B., and Kone, B. C. Effects of NF-kappa B inhibition on mesenteric ischemia-reperfusion injury. Am. J. Physiol. 284: G713, 2003.
    • (2003) Am. J. Physiol , vol.284
    • Zou, L.1    Attuwaybi, B.2    Kone, B.C.3
  • 16
    • 0037215550 scopus 로고    scopus 로고
    • Delayed treatment with MLN519 reduces infarction and associated neurologic deficit caused by focal ischemic brain injury in rats via antiinflammatory mechanisms involving nuclear factor-kappaB activation, gliosis, and leukocyte infiltration
    • Williams, A. J., Hale, S. L., Moffett, J. R., et al. Delayed treatment with MLN519 reduces infarction and associated neurologic deficit caused by focal ischemic brain injury in rats via antiinflammatory mechanisms involving nuclear factor-kappaB activation, gliosis, and leukocyte infiltration. J. Cereb. Blood Flow Metab. 23: 75, 2003.
    • (2003) J. Cereb. Blood Flow Metab , vol.23 , pp. 75
    • Williams, A.J.1    Hale, S.L.2    Moffett, J.R.3
  • 17
    • 0035087552 scopus 로고    scopus 로고
    • Inhibition of the initial wave of NF-kappaB activity in rat muscle reduces ischemia/ reperfusion injury
    • Lille, S. T., Lefler, S. R., Mowlavi, A., et al. Inhibition of the initial wave of NF-kappaB activity in rat muscle reduces ischemia/ reperfusion injury. Muscle Nerve 24: 534, 2001.
    • (2001) Muscle Nerve , vol.24 , pp. 534
    • Lille, S.T.1    Lefler, S.R.2    Mowlavi, A.3
  • 18
    • 0032988969 scopus 로고    scopus 로고
    • Early activation of transcription factor NF-kappaB during ischemia in perfused rat heart
    • Li, C., Browder, W., and Kao, R. L. Early activation of transcription factor NF-kappaB during ischemia in perfused rat heart. Am. J. Physiol. 276: H543, 1999.
    • (1999) Am. J. Physiol , vol.276
    • Li, C.1    Browder, W.2    Kao, R.L.3
  • 19
    • 0035826728 scopus 로고    scopus 로고
    • Ischemiareperfusion of rat myocardium activates nuclear factor-kappaB and induces neutrophil infiltration via lipopolysaccharide-induced CXC chemokine
    • Chandrasekar, B., Smith, J. B., and Freeman, G. L. Ischemiareperfusion of rat myocardium activates nuclear factor-kappaB and induces neutrophil infiltration via lipopolysaccharide-induced CXC chemokine. Circulation 103: 2296, 2001.
    • (2001) Circulation , vol.103 , pp. 2296
    • Chandrasekar, B.1    Smith, J.B.2    Freeman, G.L.3
  • 20
    • 0036081426 scopus 로고    scopus 로고
    • Oxygen radicals trigger activation of NF-kappaB and AP-1 and upregulation of ICAM-1 in reperfused canine heart
    • Fan, H., Sun, B., Gu, Q., et al. Oxygen radicals trigger activation of NF-kappaB and AP-1 and upregulation of ICAM-1 in reperfused canine heart. Am. J. Physiol. 282: H1778, 2002.
    • (2002) Am. J. Physiol , vol.282
    • Fan, H.1    Sun, B.2    Gu, Q.3
  • 21
    • 0036285014 scopus 로고    scopus 로고
    • Simulated ischemia induces renal tubular cell apoptosis through a nuclear factor-kappaB dependent mechanism
    • Meldrum, K. K., Hile, K., Meldrum, D. R., et al. Simulated ischemia induces renal tubular cell apoptosis through a nuclear factor-kappaB dependent mechanism. J. Urol. 168: 248, 2002.
    • (2002) J. Urol , vol.168 , pp. 248
    • Meldrum, K.K.1    Hile, K.2    Meldrum, D.R.3
  • 23
    • 0034061930 scopus 로고    scopus 로고
    • Transcription factor nuclear factor-kappa B is activated in neurons after focal cerebral ischemia
    • Stephenson, D., Yin, T., Smalstig, E. B., et al. Transcription factor nuclear factor-kappa B is activated in neurons after focal cerebral ischemia. J. Cereb. Blood Flow Metab. 20: 592, 2000.
    • (2000) J. Cereb. Blood Flow Metab , vol.20 , pp. 592
    • Stephenson, D.1    Yin, T.2    Smalstig, E.B.3
  • 24
    • 0037352329 scopus 로고    scopus 로고
    • Role of nuclear factor-kappaB activation in acute ischaemia-reperfusion injury in myocardium
    • Kis, A., Yellon, D. M., and Baxter, G. F. Role of nuclear factor-kappaB activation in acute ischaemia-reperfusion injury in myocardium. Br. J. Pharmacol. 138: 894, 2003.
    • (2003) Br. J. Pharmacol , vol.138 , pp. 894
    • Kis, A.1    Yellon, D.M.2    Baxter, G.F.3
  • 25
    • 0036190344 scopus 로고    scopus 로고
    • Absence of inducible nitric oxide synthase modulates early reperfusion-induced NF-kappaB and AP-1 activation and enhances myocardial damage
    • Zingarelli, B., Hake, P. W., Yang, Z., et al. Absence of inducible nitric oxide synthase modulates early reperfusion-induced NF-kappaB and AP-1 activation and enhances myocardial damage. F.A.S.E.B. J. 16: 327, 2002.
    • (2002) F.A.S.E.B. J , vol.16 , pp. 327
    • Zingarelli, B.1    Hake, P.W.2    Yang, Z.3
  • 26
    • 0037852202 scopus 로고    scopus 로고
    • The proteasome: Structure, function, and role in the cell
    • Adams, J. The proteasome: Structure, function, and role in the cell. Cancer Treat. Rev. 29 (Suppl. 1): 3, 2003.
    • (2003) Cancer Treat. Rev , vol.29 , Issue.SUPPL. 1 , pp. 3
    • Adams, J.1
  • 27
    • 0037370653 scopus 로고    scopus 로고
    • Proteasome inhibition ablates activation of NF-kappa B in myocardial reperfusion and reduces reperfusion injury
    • Pye, J., Ardeshirpour, F., McCain, A., et al. Proteasome inhibition ablates activation of NF-kappa B in myocardial reperfusion and reduces reperfusion injury. Am. J. Physiol. 284: H919, 2003.
    • (2003) Am. J. Physiol , vol.284
    • Pye, J.1    Ardeshirpour, F.2    McCain, A.3
  • 28
    • 0035665515 scopus 로고    scopus 로고
    • PR-39 and PR-11 peptides inhibit ischemia-reperfusion injury by blocking proteasome-mediated I kappa B alpha degradation
    • Bao, J., Sato, K., Li, M., et al. PR-39 and PR-11 peptides inhibit ischemia-reperfusion injury by blocking proteasome-mediated I kappa B alpha degradation. Am. J. Physiol. 281: H2612, 2001.
    • (2001) Am. J. Physiol , vol.281
    • Bao, J.1    Sato, K.2    Li, M.3
  • 29
    • 0033947161 scopus 로고    scopus 로고
    • Regulation of E-selectin expression in postischemic intestinal microvasculature
    • Russell, J., Epstein, C. J., Grisham, M. B., et al. Regulation of E-selectin expression in postischemic intestinal microvasculature. Am. J. Physiol. 278: G878, 2000.
    • (2000) Am. J. Physiol , vol.278
    • Russell, J.1    Epstein, C.J.2    Grisham, M.B.3
  • 30
    • 0025152032 scopus 로고
    • Vasodilator action of prostaglandin E1 on microcirculation of rat cremaster muscle
    • Chen, L. E., Seaber, A. V., and Urbaniak, J. R. Vasodilator action of prostaglandin E1 on microcirculation of rat cremaster muscle. Microsurgery 11: 204, 1990.
    • (1990) Microsurgery , vol.11 , pp. 204
    • Chen, L.E.1    Seaber, A.V.2    Urbaniak, J.R.3
  • 31
    • 21644468142 scopus 로고    scopus 로고
    • Skeletal muscle reperfusion injury is enhanced in extracellular superoxide dismutase knockout mouse
    • Park, J. W., Qi, W. N., Cai, Y., et al. Skeletal muscle reperfusion injury is enhanced in extracellular superoxide dismutase knockout mouse. Am. J. Physiol. 289: H181, 2005.
    • (2005) Am. J. Physiol , vol.289
    • Park, J.W.1    Qi, W.N.2    Cai, Y.3
  • 32
    • 0033918122 scopus 로고    scopus 로고
    • Proteasome inhibitor PS519 reduces infarction and attenuates leukocyte infiltration in a rat model of focal cerebral ischemia
    • Phillips, J. B., Williams, A. J., Adams, J., et al. Proteasome inhibitor PS519 reduces infarction and attenuates leukocyte infiltration in a rat model of focal cerebral ischemia. Stroke 31: 1686, 2000.
    • (2000) Stroke , vol.31 , pp. 1686
    • Phillips, J.B.1    Williams, A.J.2    Adams, J.3
  • 33
    • 0034717368 scopus 로고    scopus 로고
    • Is nuclear factor-kappaB a good treatment target in brain ischemia/ reperfusion injury?
    • Carroll, J. E., Hess, D. C., Howard, E. F., et al. Is nuclear factor-kappaB a good treatment target in brain ischemia/ reperfusion injury? Neuroreport 11: R1, 2000.
    • (2000) Neuroreport , vol.11
    • Carroll, J.E.1    Hess, D.C.2    Howard, E.F.3
  • 34
    • 0033595892 scopus 로고    scopus 로고
    • The Rel/NF-kappaB signal transduction pathway: Introduction
    • Gilmore, T. D. The Rel/NF-kappaB signal transduction pathway: Introduction. Oncogene 18: 6842, 1999.
    • (1999) Oncogene , vol.18 , pp. 6842
    • Gilmore, T.D.1
  • 35
    • 0027939931 scopus 로고
    • Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase
    • Xie, Q. W., Kashiwabara, Y., and Nathan, C. Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase. J. Biol. Chem. 269: 4705, 1994.
    • (1994) J. Biol. Chem , vol.269 , pp. 4705
    • Xie, Q.W.1    Kashiwabara, Y.2    Nathan, C.3
  • 36
    • 0037569481 scopus 로고    scopus 로고
    • Proteosome inhibition: A new anti-inflammatory strategy
    • Elliott, P. J., Zollner, T. M., and Boehncke, W. H. Proteosome inhibition: A new anti-inflammatory strategy. J. Mol. Med. 81: 235, 2003.
    • (2003) J. Mol. Med , vol.81 , pp. 235
    • Elliott, P.J.1    Zollner, T.M.2    Boehncke, W.H.3
  • 37
    • 0031794430 scopus 로고    scopus 로고
    • NO inhibits cytokine-induced iNOS expression and NF-kappaB activation by interfering with phosphorylation and degradation of IkappaB-alpha
    • Katsuyama, K., Shichiri, M., Marumo, F., et al. NO inhibits cytokine-induced iNOS expression and NF-kappaB activation by interfering with phosphorylation and degradation of IkappaB-alpha. Arterioscler. Thromb. Vasc. Biol. 18: 1796, 1998.
    • (1998) Arterioscler. Thromb. Vasc. Biol , vol.18 , pp. 1796
    • Katsuyama, K.1    Shichiri, M.2    Marumo, F.3
  • 38
    • 0030061515 scopus 로고    scopus 로고
    • Transcriptional regulation of human inducible nitric oxide synthase (NOS2) gene by cytokines: Initial analysis of the human NOS2 promoter
    • de Vera, M. E., Shapiro, R. A., Nussler, A. K., et al. Transcriptional regulation of human inducible nitric oxide synthase (NOS2) gene by cytokines: Initial analysis of the human NOS2 promoter. Proc. Natl. Acad. Sci. U.S.A. 93: 1054, 1996.
    • (1996) Proc. Natl. Acad. Sci. U.S.A , vol.93 , pp. 1054
    • de Vera, M.E.1    Shapiro, R.A.2    Nussler, A.K.3
  • 39
    • 0029016407 scopus 로고
    • Inducible nitric oxide synthase: Regulation subserves function
    • Nathan, C. Inducible nitric oxide synthase: Regulation subserves function. Curr. Top. Microbiol. Immunol. 196: 1, 1995.
    • (1995) Curr. Top. Microbiol. Immunol , vol.196 , pp. 1
    • Nathan, C.1
  • 40
    • 0028946614 scopus 로고
    • Transcriptional inhibition of the inducible nitric oxide synthase gene by competitive binding of NF-kappa B/Rel proteins
    • Goldring, C. E., Narayanan, R., Lagadec, P., et al. Transcriptional inhibition of the inducible nitric oxide synthase gene by competitive binding of NF-kappa B/Rel proteins. Biochem. Biophys. Res. Commun. 209: 73, 1995.
    • (1995) Biochem. Biophys. Res. Commun , vol.209 , pp. 73
    • Goldring, C.E.1    Narayanan, R.2    Lagadec, P.3
  • 41
    • 0037489515 scopus 로고    scopus 로고
    • Critical role of reactive nitrogen species in lung ischemia-reperfusion injury
    • Naidu, B. V., Fraga, C., Salzman, A. L., et al. Critical role of reactive nitrogen species in lung ischemia-reperfusion injury. J. Heart Lung Transplant. 22: 784, 2003.
    • (2003) J. Heart Lung Transplant , vol.22 , pp. 784
    • Naidu, B.V.1    Fraga, C.2    Salzman, A.L.3
  • 42
    • 0034123171 scopus 로고    scopus 로고
    • Interactions of oxidants with vascular signaling systems
    • Wolin, M. S. Interactions of oxidants with vascular signaling systems. Arterioscler. Thromb. Vasc. Biol. 20: 1430, 2000.
    • (2000) Arterioscler. Thromb. Vasc. Biol , vol.20 , pp. 1430
    • Wolin, M.S.1
  • 43
    • 0035146094 scopus 로고    scopus 로고
    • Activation of NF kappa B and expression of ICAM-1 in ischemic-reperfused canine myocardium
    • Sun, B., Fan, H., and Honda, T. Activation of NF kappa B and expression of ICAM-1 in ischemic-reperfused canine myocardium. J. Mol. Cell. Cardiol. 33: 109, 2001.
    • (2001) J. Mol. Cell. Cardiol , vol.33 , pp. 109
    • Sun, B.1    Fan, H.2    Honda, T.3
  • 44
    • 0036174993 scopus 로고    scopus 로고
    • Pyrrolidine dithiocarbamate attenuates the development of acute and chronic inflammation
    • Cuzzocrea, S., Chatterjee, P. K., and Mazzon, E. Pyrrolidine dithiocarbamate attenuates the development of acute and chronic inflammation. Br. J. Pharmacol. 135: 496, 2002.
    • (2002) Br. J. Pharmacol , vol.135 , pp. 496
    • Cuzzocrea, S.1    Chatterjee, P.K.2    Mazzon, E.3
  • 45
    • 0036190630 scopus 로고    scopus 로고
    • Inhibitory effects of pyrrolidine dithiocarbamate on endotoxin-induced uveitis in Lewis rats
    • Ohta, K., Nakayama, K., and Kurokawa, T. Inhibitory effects of pyrrolidine dithiocarbamate on endotoxin-induced uveitis in Lewis rats. Invest. Ophthalmol. Vis. Sci. 43: 744, 2002.
    • (2002) Invest. Ophthalmol. Vis. Sci , vol.43 , pp. 744
    • Ohta, K.1    Nakayama, K.2    Kurokawa, T.3
  • 46
    • 0033592288 scopus 로고    scopus 로고
    • Inhibition of NF-kappaB activation by pyrrolidine dithiocarbamate prevents in vivo expression of proinflammatory genes
    • Liu, S. F., Ye, X., and Malik, A. B. Inhibition of NF-kappaB activation by pyrrolidine dithiocarbamate prevents in vivo expression of proinflammatory genes. Circulation 100: 1330, 1999.
    • (1999) Circulation , vol.100 , pp. 1330
    • Liu, S.F.1    Ye, X.2    Malik, A.B.3
  • 47
    • 0032486242 scopus 로고    scopus 로고
    • NF-kappa B is activated and ICAM-1 gene expression is upregulated during reoxygenation of human brain endothelial cells
    • Howard, E. F., Chen, Q., and Cheng, C. NF-kappa B is activated and ICAM-1 gene expression is upregulated during reoxygenation of human brain endothelial cells. Neurosci. Lett. 248: 199, 1998.
    • (1998) Neurosci. Lett , vol.248 , pp. 199
    • Howard, E.F.1    Chen, Q.2    Cheng, C.3
  • 48
    • 0033844442 scopus 로고    scopus 로고
    • Tacrolimus limits polymorphonuclear leucocyte accumulation and protects against myocardial ischaemia-reperfusion injury
    • Squadrito, F., Altavilla, D., and Squadrito, G. Tacrolimus limits polymorphonuclear leucocyte accumulation and protects against myocardial ischaemia-reperfusion injury. J. Mol. Cell. Cardiol. 32: 429, 2000.
    • (2000) J. Mol. Cell. Cardiol , vol.32 , pp. 429
    • Squadrito, F.1    Altavilla, D.2    Squadrito, G.3
  • 49
    • 0033525736 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha contributes to ischemia- and reperfusion-induced endothelial activation in isolated hearts
    • Kupatt, C., Habazettl, H., and Goedecke, A. Tumor necrosis factor-alpha contributes to ischemia- and reperfusion-induced endothelial activation in isolated hearts. Circ. Res. 84: 392, 1999.
    • (1999) Circ. Res , vol.84 , pp. 392
    • Kupatt, C.1    Habazettl, H.2    Goedecke, A.3
  • 50
    • 0033847049 scopus 로고    scopus 로고
    • Inhibition of ubiquitinproteasome pathway-mediated I kappa B alpha degradation by a naturally occurring antibacterial peptide
    • Gao, Y., Lecker, S., and Post, M. J. Inhibition of ubiquitinproteasome pathway-mediated I kappa B alpha degradation by a naturally occurring antibacterial peptide. J. Clin. Invest. 106: 439, 2000.
    • (2000) J. Clin. Invest , vol.106 , pp. 439
    • Gao, Y.1    Lecker, S.2    Post, M.J.3
  • 51
    • 0034902354 scopus 로고    scopus 로고
    • Novel proteasome inhibitor PS-341 inhibits activation of nuclear factor-kappa B, cell survival, tumor growth, and angiogenesis in squamous cell carcinoma
    • Sunwoo, J. B., Chen, Z., and Dong, G. Novel proteasome inhibitor PS-341 inhibits activation of nuclear factor-kappa B, cell survival, tumor growth, and angiogenesis in squamous cell carcinoma. Clin. Cancer Res. 7: 1419, 2001.
    • (2001) Clin. Cancer Res , vol.7 , pp. 1419
    • Sunwoo, J.B.1    Chen, Z.2    Dong, G.3
  • 52
    • 0037111832 scopus 로고    scopus 로고
    • Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies
    • Orlowski, R. Z., Stinchcombe, T. E., and Mitchell, B. S. Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies. J. Clin. Oncol. 20: 4420, 2002.
    • (2002) J. Clin. Oncol , vol.20 , pp. 4420
    • Orlowski, R.Z.1    Stinchcombe, T.E.2    Mitchell, B.S.3
  • 53
    • 18544367201 scopus 로고    scopus 로고
    • NF-kappa B as a therapeutic target in multiple myeloma
    • Hideshima, T., Chauhan, D., and Richardson, P. NF-kappa B as a therapeutic target in multiple myeloma. J. Biol. Chem. 277: 16639, 2002.
    • (2002) J. Biol. Chem , vol.277 , pp. 16639
    • Hideshima, T.1    Chauhan, D.2    Richardson, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.