메뉴 건너뛰기




Volumn 5, Issue 8, 2006, Pages 2043-2050

Bortezomib inhibits docetaxel-induced apoptosis via a p21-dependent mechanism in human prostate cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; BORTEZOMIB; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE INHIBITOR; DOCETAXEL; OLOMOUCINE; PHOSPHOTRANSFERASE; PROTEIN P21; ROSCOVITINE; SMALL INTERFERING RNA;

EID: 33748369901     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-05-0437     Document Type: Article
Times cited : (39)

References (55)
  • 2
    • 0037407154 scopus 로고    scopus 로고
    • The natural history of prostate cancer
    • Kessler B, Albertsen P. The natural history of prostate cancer. Urol Clin North Am 2003;30:219-26.
    • (2003) Urol Clin North Am , vol.30 , pp. 219-226
    • Kessler, B.1    Albertsen, P.2
  • 3
    • 0034784577 scopus 로고    scopus 로고
    • Preliminary observations of single-agent docetaxel as neoadjuvant therapy for locally advanced prostate cancer
    • Dreicer R, Klein EA. Preliminary observations of single-agent docetaxel as neoadjuvant therapy for locally advanced prostate cancer. Semin Oncol 2001;28:45-8.
    • (2001) Semin Oncol , vol.28 , pp. 45-48
    • Dreicer, R.1    Klein, E.A.2
  • 4
    • 0034795825 scopus 로고    scopus 로고
    • Neoadjuvant docetaxel followed by radical prostatectomy in patients with high-risk localized prostate cancer: A preliminary report
    • Oh WK, George DJ, Kaufman DS, et al. Neoadjuvant docetaxel followed by radical prostatectomy in patients with high-risk localized prostate cancer: a preliminary report. Semin Oncol 2001;28:40-4.
    • (2001) Semin Oncol , vol.28 , pp. 40-44
    • Oh, W.K.1    George, D.J.2    Kaufman, D.S.3
  • 5
    • 2342667387 scopus 로고    scopus 로고
    • The development of proteasome inhibitors as anticancer drugs
    • Adams J. The development of proteasome inhibitors as anticancer drugs. Cancer Cell 2004; 5:417-21.
    • (2004) Cancer Cell , vol.5 , pp. 417-421
    • Adams, J.1
  • 6
    • 0033152760 scopus 로고    scopus 로고
    • Proteasome inhibitors: A novel class of potent and effective antitumor agents
    • Adams J, Palombella VJ, Sausville EA, et al. Proteasome inhibitors: a novel class of potent and effective antitumor agents. Cancer Res 1999; 59:2615-22.
    • (1999) Cancer Res , vol.59 , pp. 2615-2622
    • Adams, J.1    Palombella, V.J.2    Sausville, E.A.3
  • 7
    • 0037973279 scopus 로고    scopus 로고
    • A phase 2 study of bortezomib in relapsed, refractory myeloma
    • Richardson PG, Barlogie B, Berenson J, et al. A phase 2 study of bortezomib in relapsed, refractory myeloma. N Engl J Mad 2003;348: 2609-17.
    • (2003) N Engl J Med , vol.348 , pp. 2609-2617
    • Richardson, P.G.1    Barlogie, B.2    Berenson, J.3
  • 8
    • 0345447210 scopus 로고    scopus 로고
    • Velcade: U.S. FDA approval for the treatment of multiple myeloma progressing on prior therapy
    • Kane RC, Bross PF, Farrell AT, Pazdur R. Velcade: U.S. FDA approval for the treatment of multiple myeloma progressing on prior therapy. Oncologist 2003;8:508-13.
    • (2003) Oncologist , vol.8 , pp. 508-513
    • Kane, R.C.1    Bross, P.F.2    Farrell, A.T.3    Pazdur, R.4
  • 9
    • 0000640680 scopus 로고    scopus 로고
    • PS-341 enhances chemotherapeutic effects in human xenograph models
    • Pink MM, Pien CS, Worland P, et al. PS-341 enhances chemotherapeutic effects in human xenograph models. Proc Am Assoc Cancer Res 2002;43:158.
    • (2002) Proc Am Assoc Cancer Res , vol.43 , pp. 158
    • Pink, M.M.1    Pien, C.S.2    Worland, P.3
  • 10
    • 0012383819 scopus 로고    scopus 로고
    • Docetaxel followed by PS-341 results in phosphorylation and stabilization of p27 and increases response in non-small cell lung carcinoma (NSCLC)
    • Gumerlock PH, Moisan LP, Lau AH, et al. Docetaxel followed by PS-341 results in phosphorylation and stabilization of p27 and increases response in non-small cell lung carcinoma (NSCLC). Clin Cancer Res 2001;7:157.
    • (2001) Clin Cancer Res , vol.7 , pp. 157
    • Gumerlock, P.H.1    Moisan, L.P.2    Lau, A.H.3
  • 11
    • 0030223057 scopus 로고    scopus 로고
    • Selection of highly metastatic variants of different human prostatic carcinomas using orthotopic implantation in nude mice
    • Pettaway CA, Pathak S, Greene G, et al. Selection of highly metastatic variants of different human prostatic carcinomas using orthotopic implantation in nude mice. Clin Cancer Res 1996;2:1627-36.
    • (1996) Clin Cancer Res , vol.2 , pp. 1627-1636
    • Pettaway, C.A.1    Pathak, S.2    Greene, G.3
  • 12
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
    • Nicoletti I, Migliorati G, Pagliacci MC, Grignani F, Riccardi C. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods 1991; 139:271-9.
    • (1991) J Immunol Methods , vol.139 , pp. 271-279
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, M.C.3    Grignani, F.4    Riccardi, C.5
  • 13
    • 3042562304 scopus 로고    scopus 로고
    • The proteasome inhibitor bortezomib enhances the activity of docetaxel in orthotopic human pancreatic tumor xenografts
    • Nawrocki ST, Sweeney-Gotsch B, Takamori R, McConkey DJ. The proteasome inhibitor bortezomib enhances the activity of docetaxel in orthotopic human pancreatic tumor xenografts. Mol Cancer Ther 2004;3: 59-70.
    • (2004) Mol Cancer Ther , vol.3 , pp. 59-70
    • Nawrocki, S.T.1    Sweeney-Gotsch, B.2    Takamori, R.3    McConkey, D.J.4
  • 14
    • 0642349188 scopus 로고    scopus 로고
    • Differential effects of the proteasome inhibitor bortezomib on apoptosis and angiogenesis in human prostate tumor xenografts
    • Williams S, Pettaway C, Song R, Papandreou C, Logothetis C, McConkey DJ. Differential effects of the proteasome inhibitor bortezomib on apoptosis and angiogenesis in human prostate tumor xenografts. Mol Cancer Ther 2003;2:835-43.
    • (2003) Mol Cancer Ther , vol.2 , pp. 835-843
    • Williams, S.1    Pettaway, C.2    Song, R.3    Papandreou, C.4    Logothetis, C.5    McConkey, D.J.6
  • 15
    • 0026428123 scopus 로고
    • Studies with RP 56976 (taxotere): A semisynthetic analogue of Taxol
    • Ringel I, Horwitz SB. Studies with RP 56976 (taxotere): a semisynthetic analogue of Taxol. J Natl Cancer Inst 1991;83:288-91.
    • (1991) J Natl Cancer Inst , vol.83 , pp. 288-291
    • Ringel, I.1    Horwitz, S.B.2
  • 16
    • 0032214980 scopus 로고    scopus 로고
    • Overexpression of ErbB2 blocks Taxolinduced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase
    • Yu D, Jing T, Liu B, et al. Overexpression of ErbB2 blocks Taxolinduced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase. Mol Cell 1998;2:581-91.
    • (1998) Mol Cell , vol.2 , pp. 581-591
    • Yu, D.1    Jing, T.2    Liu, B.3
  • 17
    • 4444235841 scopus 로고    scopus 로고
    • The proteasome inhibitor bortezomib synergizes with gemcitabine to block the growth of human 253JB-V bladder tumors in vivo
    • Kamat AM, Karashima T, Davis DW, et al, The proteasome inhibitor bortezomib synergizes with gemcitabine to block the growth of human 253JB-V bladder tumors in vivo. Mol Cancer Ther 2004;3:279-90.
    • (2004) Mol Cancer Ther , vol.3 , pp. 279-290
    • Kamat, A.M.1    Karashima, T.2    Davis, D.W.3
  • 18
    • 0242610835 scopus 로고    scopus 로고
    • The proteasome inhibitor bortezomib stabilizes a novel active form of p53 in human LNCaP-Pro5 prostate cancer cells
    • Williams SA, McConkey DJ. The proteasome inhibitor bortezomib stabilizes a novel active form of p53 in human LNCaP-Pro5 prostate cancer cells. Cancer Res 2003;63:7338-44.
    • (2003) Cancer Res , vol.63 , pp. 7338-7344
    • Williams, S.A.1    McConkey, D.J.2
  • 19
    • 0035849720 scopus 로고    scopus 로고
    • Blockade of NF-κB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis
    • Huang S, Pettaway CA, Uehara H, Bucana CD, Fidler IJ. Blockade of NF-κB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis. Oncogene 2001; 20:4188-97.
    • (2001) Oncogene , vol.20 , pp. 4188-4197
    • Huang, S.1    Pettaway, C.A.2    Uehara, H.3    Bucana, C.D.4    Fidler, I.J.5
  • 20
    • 2942692143 scopus 로고    scopus 로고
    • Phase I trial of the proteasome inhibitor bortezomib in patients with advanced solid tumors with observations in androgen-independent prostate cancer
    • Papandreou CN, Daliani DD, Nix D, et al. Phase I trial of the proteasome inhibitor bortezomib in patients with advanced solid tumors with observations in androgen-independent prostate cancer. J Clin Oncol 2004;22:2108-21.
    • (2004) J Clin Oncol , vol.22 , pp. 2108-2121
    • Papandreou, C.N.1    Daliani, D.D.2    Nix, D.3
  • 21
    • 0036671675 scopus 로고    scopus 로고
    • Chemotherapy for androgen-independent prostate cancer
    • Petrylak DP. Chemotherapy for androgen-independent prostate cancer. Semin Urol Oncol 2002;20:31-5.
    • (2002) Semin Urol Oncol , vol.20 , pp. 31-35
    • Petrylak, D.P.1
  • 22
    • 17444436904 scopus 로고    scopus 로고
    • Paclitaxel, estramustine, and etoposide in the treatment of hormone-refractory prostate cancer
    • Pienta KJ, Smith DC. Paclitaxel, estramustine, and etoposide in the treatment of hormone-refractory prostate cancer. Semin Oncol 1997;24: S15-72-7.
    • (1997) Semin Oncol , vol.24
    • Pienta, K.J.1    Smith, D.C.2
  • 23
    • 0033062292 scopus 로고    scopus 로고
    • Paclitaxel in the treatment of hormone-refractory prostate cancer
    • Smith DC, Pienta KJ. Paclitaxel in the treatment of hormone-refractory prostate cancer. Semin Oncol 1999;26:109-11.
    • (1999) Semin Oncol , vol.26 , pp. 109-111
    • Smith, D.C.1    Pienta, K.J.2
  • 24
    • 0141885308 scopus 로고    scopus 로고
    • The evolving role of docetaxel in the management of androgen independent prostate cancer
    • Khan MA, Carducci MA, Partin AW. The evolving role of docetaxel in the management of androgen independent prostate cancer. J Urol 2003; 170:1709-16.
    • (2003) J Urol , vol.170 , pp. 1709-1716
    • Khan, M.A.1    Carducci, M.A.2    Partin, A.W.3
  • 25
    • 0036615319 scopus 로고    scopus 로고
    • Docetaxel in the integrated management of prostate cancer. Current applications and future promise
    • Logothetis CJ. Docetaxel in the integrated management of prostate cancer. Current applications and future promise. Oncology (Huntingt) 2002;16:63-72.
    • (2002) Oncology (Huntingt) , vol.16 , pp. 63-72
    • Logothetis, C.J.1
  • 27
    • 2942613326 scopus 로고    scopus 로고
    • Phase II trial of neoadjuvant docetaxel before radical prostatectomy for locally advanced prostate cancer
    • Dreicer R, Magi-Galluzzi C, Zhou M, et al. Phase II trial of neoadjuvant docetaxel before radical prostatectomy for locally advanced prostate cancer. Urology 2004;63:1138-42.
    • (2004) Urology , vol.63 , pp. 1138-1142
    • Dreicer, R.1    Magi-Galluzzi, C.2    Zhou, M.3
  • 28
    • 0037382623 scopus 로고    scopus 로고
    • Neoadjuvant docetaxel and estramustine chemotherapy in high-risk/locally advanced prostate cancer
    • Hussain M, Smith DC, El-Rayes BF, et al. Neoadjuvant docetaxel and estramustine chemotherapy in high-risk/locally advanced prostate cancer. Urology 2003;61:774-80.
    • (2003) Urology , vol.61 , pp. 774-780
    • Hussain, M.1    Smith, D.C.2    El-Rayes, B.F.3
  • 29
    • 0033993630 scopus 로고    scopus 로고
    • Neoadjuvant chemotherapy and hormonal therapy followed by radical prostatectomy: Feasibility and preliminary results
    • Pettaway CA, Pisters LL, Troncoso P, et al. Neoadjuvant chemotherapy and hormonal therapy followed by radical prostatectomy: feasibility and preliminary results. J Clin Oncol 2000;18:1050-7.
    • (2000) J Clin Oncol , vol.18 , pp. 1050-1057
    • Pettaway, C.A.1    Pisters, L.L.2    Troncoso, P.3
  • 30
    • 0141725730 scopus 로고    scopus 로고
    • Mode of action of docetaxel-a basis for combination with novel anticancer agents
    • Herbst RS, Khuri FR. Mode of action of docetaxel-a basis for combination with novel anticancer agents. Cancer Treat Rev 2003;29:407-15.
    • (2003) Cancer Treat Rev , vol.29 , pp. 407-415
    • Herbst, R.S.1    Khuri, F.R.2
  • 31
    • 0036124415 scopus 로고    scopus 로고
    • Epidermal growth factor receptors as a target for cancer treatment: The emerging role of IMC-C225 in the treatment of lung and head and neck cancers
    • Herbst RS, Langer CJ. Epidermal growth factor receptors as a target for cancer treatment: the emerging role of IMC-C225 in the treatment of lung and head and neck cancers. Semin Oncol 2002;29:27-36.
    • (2002) Semin Oncol , vol.29 , pp. 27-36
    • Herbst, R.S.1    Langer, C.J.2
  • 32
    • 0000747846 scopus 로고    scopus 로고
    • A phase II trial of docetaxel and herceptin in metastatic breast cancer patients overexpressing HER-2
    • Kuzur ME AK, Huntington MO, et al. A phase II trial of docetaxel and herceptin in metastatic breast cancer patients overexpressing HER-2. Proc Am Soc Clin Oncol 2000;19:512.
    • (2000) Proc Am Soc Clin Oncol , vol.19 , pp. 512
    • Kuzur, M.E.A.K.1    Huntington, M.O.2
  • 33
    • 0003200095 scopus 로고    scopus 로고
    • A phase II trial of weekly docetaxel (D) and herceptin (H) as first-or second-line treatment in HER-2 overexpressing metastatic breast cancer
    • Uber KA, Nicholson BP, Thor AD, et al. A phase II trial of weekly docetaxel (D) and herceptin (H) as first-or second-line treatment in HER-2 overexpressing metastatic breast cancer. Proc Am Soc Clin Oncol 2001; 20:1949.
    • (2001) Proc Am Soc Clin Oncol , vol.20 , pp. 1949
    • Uber, K.A.1    Nicholson, B.P.2    Thor, A.D.3
  • 34
    • 0036534121 scopus 로고    scopus 로고
    • Phase II study of weekly docetaxel and trastuzumab for patients with HER-2-overexpressing metastatic breast cancer
    • Esteva FJ, Valero V, Booser D, et al. Phase II study of weekly docetaxel and trastuzumab for patients with HER-2-overexpressing metastatic breast cancer. J Clin Oncol 2002;20:1800-8.
    • (2002) J Clin Oncol , vol.20 , pp. 1800-1808
    • Esteva, F.J.1    Valero, V.2    Booser, D.3
  • 35
    • 0035015136 scopus 로고    scopus 로고
    • Weekly intravenous recombinant humanized anti-P185HER2 monoclonal antibody (herceptin) plus docetaxel in patients with metastatic breast cancer: A pilot study
    • Meden H, Beneke A, Hesse T, Novophashenny I, Wischnewsky M. Weekly intravenous recombinant humanized anti-P185HER2 monoclonal antibody (herceptin) plus docetaxel in patients with metastatic breast cancer: a pilot study. Anticancer Res 2001;21:1301-5.
    • (2001) Anticancer Res , vol.21 , pp. 1301-1305
    • Meden, H.1    Beneke, A.2    Hesse, T.3    Novophashenny, I.4    Wischnewsky, M.5
  • 36
    • 0000165438 scopus 로고    scopus 로고
    • A phase I, clinical and pharmacolkinetic (PK) trial of the farnesyl transferase inhibitor (FTI) R115777 + docetaxel: A promising combination in patient (PTS) with solid tumors
    • Piccart MJ, Branie F, de Valeriola M, et al. A phase I, clinical and pharmacolkinetic (PK) trial of the farnesyl transferase inhibitor (FTI) R115777 + docetaxel: a promising combination in patient (PTS) with solid tumors. Proc Am Soc Clin Oncol 2001;20:318.
    • (2001) Proc Am Soc Clin Oncol , vol.20 , pp. 318
    • Piccart, M.J.1    Branie, F.2    de Valeriola, M.3
  • 37
    • 4243079972 scopus 로고    scopus 로고
    • A phase I pharmacokinetic and biological correlative study of oblimersen sodium (genasense, g3139), an antisense oligonucleotide to the bcl-2 mRNA, and of docetaxel in patients with hormone-refractory prostate cancer
    • Tolcher AW, Kuhn J, Schwartz G, et al. A phase I pharmacokinetic and biological correlative study of oblimersen sodium (genasense, g3139), an antisense oligonucleotide to the bcl-2 mRNA, and of docetaxel in patients with hormone-refractory prostate cancer. Clin Cancer Res 2004;10:5048-57.
    • (2004) Clin Cancer Res , vol.10 , pp. 5048-5057
    • Tolcher, A.W.1    Kuhn, J.2    Schwartz, G.3
  • 38
    • 0000700128 scopus 로고    scopus 로고
    • BCL-2 antisense (G3139) plus docetaxel for treatment of progressive androgen-independent prostate cancer
    • Morris MJ, Tong WP, Cordon-Cardo C, et al. BCL-2 antisense (G3139) plus docetaxel for treatment of progressive androgen-independent prostate cancer. Eur J Cancer 2001;37:218.
    • (2001) Eur J Cancer , vol.37 , pp. 218
    • Morris, M.J.1    Tong, W.P.2    Cordon-Cardo, C.3
  • 39
    • 18644367630 scopus 로고    scopus 로고
    • The function of multiple IκB: NFκB complexes in the resistance of cancer cells to Taxol-induced apoptosis
    • Dong QG, Sclabas GM, Fujioka S, et al. The function of multiple IκB: NFκB complexes in the resistance of cancer cells to Taxol-induced apoptosis. Oncogene 2002;21:6510-9.
    • (2002) Oncogene , vol.21 , pp. 6510-6519
    • Dong, Q.G.1    Sclabas, G.M.2    Fujioka, S.3
  • 40
    • 17644421083 scopus 로고    scopus 로고
    • Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy
    • Tan TT, Degenhardt K, Nelson DA, et al. Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy. Cancer Cell 2005;7:227-38.
    • (2005) Cancer Cell , vol.7 , pp. 227-238
    • Tan, T.T.1    Degenhardt, K.2    Nelson, D.A.3
  • 41
    • 4043095823 scopus 로고    scopus 로고
    • Differential apoptotic response to the proteasome inhibitor Bortezomib [VELCADE, PS-341] in Bax-deficient and p21-deficient colon cancer cells
    • Yu J, Tiwari S, Steiner P, Zhang L. Differential apoptotic response to the proteasome inhibitor Bortezomib [VELCADE, PS-341] in Bax-deficient and p21-deficient colon cancer cells. Cancer Biol Ther 2003;2:694-9.
    • (2003) Cancer Biol Ther , vol.2 , pp. 694-699
    • Yu, J.1    Tiwari, S.2    Steiner, P.3    Zhang, L.4
  • 42
    • 4444377057 scopus 로고    scopus 로고
    • Human somatic cell knockouts reveal determinants of sensitivity and resistance to proteasome inhibitor PS-341
    • Lee C, Waldman T. Human somatic cell knockouts reveal determinants of sensitivity and resistance to proteasome inhibitor PS-341. Cancer Biol Ther 2003;2:700-1.
    • (2003) Cancer Biol Ther , vol.2 , pp. 700-701
    • Lee, C.1    Waldman, T.2
  • 43
    • 9244224723 scopus 로고    scopus 로고
    • Intrinsic tumour suppression
    • Lowe SW, Cepero E, Evan G. Intrinsic tumour suppression. Nature 2004;432:307-15.
    • (2004) Nature , vol.432 , pp. 307-3015
    • Lowe, S.W.1    Cepero, E.2    Evan, G.3
  • 44
    • 0347628818 scopus 로고    scopus 로고
    • p21Waf1/Cip1 as a therapeutic target in breast and other cancers
    • Weiss RH. p21Waf1/Cip1 as a therapeutic target in breast and other cancers. Cancer Cell 2003;4:425-9.
    • (2003) Cancer Cell , vol.4 , pp. 425-429
    • Weiss, R.H.1
  • 45
    • 19644395562 scopus 로고    scopus 로고
    • Bortezomib abolishes tumor necrosis factor-related apoptosis-inducing ligand resistance via a p21-dependent mechanism in human bladder and prostate cancer cells
    • Lashinger LM, Zhu K, Williams SA, Shrader M, Dinney CP, McConkey DJ. Bortezomib abolishes tumor necrosis factor-related apoptosis-inducing ligand resistance via a p21-dependent mechanism in human bladder and prostate cancer cells. Cancer Res 2005;65:4902-8.
    • (2005) Cancer Res , vol.65 , pp. 4902-4908
    • Lashinger, L.M.1    Zhu, K.2    Williams, S.A.3    Shrader, M.4    Dinney, C.P.5    McConkey, D.J.6
  • 46
    • 18544367201 scopus 로고    scopus 로고
    • NF-κB as a therapeutic target in multiple myeloma
    • Hideshima T, Chauhan D, Richardson P, et al. NF-κB as a therapeutic target in multiple myeloma. J Biol Chem 2002;277:16639-47.
    • (2002) J Biol Chem , vol.277 , pp. 16639-16647
    • Hideshima, T.1    Chauhan, D.2    Richardson, P.3
  • 47
    • 0141706672 scopus 로고    scopus 로고
    • Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic response to bortezomib, a novel proteasome inhibitor, in human H460 non-small cell lung cancer cells
    • Ling YH, Liebes L, Zou Y, Perez-Soler R. Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic response to bortezomib, a novel proteasome inhibitor, in human H460 non-small cell lung cancer cells. J Biol Chem 2003;278:33714-23.
    • (2003) J Biol Chem , vol.278 , pp. 33714-33723
    • Ling, Y.H.1    Liebes, L.2    Zou, Y.3    Perez-Soler, R.4
  • 48
    • 2542523228 scopus 로고    scopus 로고
    • Synergistic induction of oxidative injury and apoptosis in human multiple myeloma cells by the proteasome inhibitor bortezomib and histone deacetylase inhibitors
    • Pei XY, Dai Y, Grant S. Synergistic induction of oxidative injury and apoptosis in human multiple myeloma cells by the proteasome inhibitor bortezomib and histone deacetylase inhibitors. Clin Cancer Res 2004;10: 3839-52.
    • (2004) Clin Cancer Res , vol.10 , pp. 3839-3852
    • Pei, X.Y.1    Dai, Y.2    Grant, S.3
  • 49
    • 1842861723 scopus 로고    scopus 로고
    • The hierarchical relationship between MAPK signaling and ROS generation in human leukemia cells undergoing apoptosis in response to the proteasome inhibitor bortezomib
    • Yu C, Rahmani M, Dent P, Grant S. The hierarchical relationship between MAPK signaling and ROS generation in human leukemia cells undergoing apoptosis in response to the proteasome inhibitor bortezomib. Exp Cell Res 2004;295:555-66.
    • (2004) Exp Cell Res , vol.295 , pp. 555-566
    • Yu, C.1    Rahmani, M.2    Dent, P.3    Grant, S.4
  • 50
    • 7644242953 scopus 로고    scopus 로고
    • Proteasome inhibitor PS-341 induces apoptosis through induction of endoplasmic reticulum stress-reactive oxygen species in head and neck squamous cell carcinoma cells
    • Fribley A, Zang Q, Wang CY. Proteasome inhibitor PS-341 induces apoptosis through induction of endoplasmic reticulum stress-reactive oxygen species in head and neck squamous cell carcinoma cells. Mol Cell Biol 2004;24:9695-704.
    • (2004) Mol Cell Biol , vol.24 , pp. 9695-9704
    • Fribley, A.1    Zang, Q.2    Wang, C.Y.3
  • 51
    • 20844435806 scopus 로고    scopus 로고
    • Small-molecule inhibition of proteasome and aggresome function induces synergistic antitumor activity in multiple myeloma
    • Hideshima T, Bradner JE, Wong J, et al. Small-molecule inhibition of proteasome and aggresome function induces synergistic antitumor activity in multiple myeloma. Proc Natl Acad Sci U S A 2005;102:8567-72.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 8567-8572
    • Hideshima, T.1    Bradner, J.E.2    Wong, J.3
  • 52
    • 33645737411 scopus 로고    scopus 로고
    • Aggresome disruption: A novel strategy to enhance bortezomib-induced apoptosis in pancreatic cancer cells
    • Nawrocki ST, Carew JS, Pino MS, et al. Aggresome disruption: a novel strategy to enhance bortezomib-induced apoptosis in pancreatic cancer cells. Cancer Res 2006;66:3773-81.
    • (2006) Cancer Res , vol.66 , pp. 3773-3781
    • Nawrocki, S.T.1    Carew, J.S.2    Pino, M.S.3
  • 53
    • 29244454269 scopus 로고    scopus 로고
    • Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis
    • Nawrocki ST, Carew JS, Pino MS, et al. Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis. Cancer Res 2005;65:11658-66.
    • (2005) Cancer Res , vol.65 , pp. 11658-11666
    • Nawrocki, S.T.1    Carew, J.S.2    Pino, M.S.3
  • 54
    • 29244470510 scopus 로고    scopus 로고
    • Bortezomib inhibits PKR-like endoplasmic reticulum (ER) kinase and induces apoptosis via ER stress in human pancreatic cancer cells
    • Nawrocki ST, Carew JS, Dunner K, Jr., et al. Bortezomib inhibits PKR-like endoplasmic reticulum (ER) kinase and induces apoptosis via ER stress in human pancreatic cancer cells. Cancer Res 2005;65:11510-9.
    • (2005) Cancer Res , vol.65 , pp. 11510-11519
    • Nawrocki, S.T.1    Carew, J.S.2    Dunner Jr., K.3
  • 55
    • 0037339961 scopus 로고    scopus 로고
    • Automated quantification of apoptosis after neoadjuvant chemotherapy for breast cancer: Early assessment predicts clinical response
    • Davis DW, Buchholz TA, Hess KR, Sahin AA, Valero V, McConkey DJ. Automated quantification of apoptosis after neoadjuvant chemotherapy for breast cancer: early assessment predicts clinical response. Clin Cancer Res 2003;9:955-60.
    • (2003) Clin Cancer Res , vol.9 , pp. 955-960
    • Davis, D.W.1    Buchholz, T.A.2    Hess, K.R.3    Sahin, A.A.4    Valero, V.5    McConkey, D.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.