Involvement of Rap-1 activation and early termination of immune synapse in CTLA-4-mediated negative signal

Hematology

Volumn 14, Issue 3, 2009, Pages 150-158

  Hara, Satoru ^a,b   Nakaseko, Chiaki ^b   Yamasaki, Sho ^a   Hattori, Masakazu ^c   Bos, Johannes L ^d   Saito, Yasushi ^b   Minato, Nagahiro ^c   Saito, Takashi ^a  

^a Institute of Physical and Chemical Research   (Japan)

^b CHIBA UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Cellular activation; Co stimulatory molecules; Signal transduction; T lymphocytes; Tolerance suppression

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; INTERLEUKIN 2; RAP1 PROTEIN; TALIN; CYTOTOXIC T-LYMPHOCYTE ANTIGEN 4; LEUKOCYTE ANTIGEN;

ANTIGEN PRESENTING CELL; ARTICLE; CELL CLONING; CELL MOTILITY; CELL STIMULATION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE ACTIVATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SYNAPSE; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; UPREGULATION; ANIMAL; CELL LINE; CELL MOTION; CYTOLOGY; DRUG POTENTIATION; ENZYME ACTIVATION; GENETICS; IMMUNOLOGICAL SYNAPSE; IMMUNOLOGY; METABOLISM; MURINAE;

ANIMALS; ANTIGENS, CD; CELL LINE; CELL MOVEMENT; ENZYME ACTIVATION; GTPASE-ACTIVATING PROTEINS; IMMUNOLOGICAL SYNAPSES; INTERLEUKIN-2; MURINAE; RAP1 GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TALIN; UP-REGULATION;

EID: 67949118936     PISSN: 10245332     EISSN: 16078454     Source Type: Journal    
DOI: 10.1179/102453309X402241     Document Type: Article

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