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Volumn 162, Issue 4, 2009, Pages 1244-1254

Capsaicin-sensitive sensory nerve fibers contribute to the generation and maintenance of skeletal fracture pain

Author keywords

analgesics; bone healing; orthopedic; periosteum

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; CAPSAICIN; NEUROFILAMENT H PROTEIN; NEUROFILAMENT PROTEIN; UNCLASSIFIED DRUG;

EID: 67949089545     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2009.05.065     Document Type: Article
Times cited : (56)

References (110)
  • 1
    • 8444238558 scopus 로고    scopus 로고
    • Periosteum: biology, regulation, and response to osteoporosis therapies
    • Allen M.R., Hock J.M., and Burr D.B. Periosteum: biology, regulation, and response to osteoporosis therapies. Bone 35 (2004) 1003-1012
    • (2004) Bone , vol.35 , pp. 1003-1012
    • Allen, M.R.1    Hock, J.M.2    Burr, D.B.3
  • 2
    • 22144434056 scopus 로고    scopus 로고
    • Expression and co-expression of VR1, CGRP, and IB4-binding glycoprotein in dorsal root ganglion neurons in rats: differences between the disc afferents and the cutaneous afferents
    • Aoki Y., Ohtori S., Takahashi K., Ino H., Douya H., Ozawa T., Saito T., and Moriya H. Expression and co-expression of VR1, CGRP, and IB4-binding glycoprotein in dorsal root ganglion neurons in rats: differences between the disc afferents and the cutaneous afferents. Spine 30 (2005) 1496-1500
    • (2005) Spine , vol.30 , pp. 1496-1500
    • Aoki, Y.1    Ohtori, S.2    Takahashi, K.3    Ino, H.4    Douya, H.5    Ozawa, T.6    Saito, T.7    Moriya, H.8
  • 3
    • 0029034576 scopus 로고
    • Immunocytochemical localization of trkA receptors in chemically identified subgroups of adult rat sensory neurons
    • Averill S., McMahon S.B., Clary D.O., Reichardt L.F., and Priestley J.V. Immunocytochemical localization of trkA receptors in chemically identified subgroups of adult rat sensory neurons. Eur J Neurosci 7 (1995) 1484-1494
    • (1995) Eur J Neurosci , vol.7 , pp. 1484-1494
    • Averill, S.1    McMahon, S.B.2    Clary, D.O.3    Reichardt, L.F.4    Priestley, J.V.5
  • 4
    • 33947577289 scopus 로고    scopus 로고
    • Capsaicin sensitive neurons role in the inflamed TMJ acute nociceptive response of female and male rats
    • Bellinger L.L., Spears R., King C.M., Dahm F., Hutchins B., Kerins C.A., and Kramer P.R. Capsaicin sensitive neurons role in the inflamed TMJ acute nociceptive response of female and male rats. Physiol Behav 90 (2007) 782-789
    • (2007) Physiol Behav , vol.90 , pp. 782-789
    • Bellinger, L.L.1    Spears, R.2    King, C.M.3    Dahm, F.4    Hutchins, B.5    Kerins, C.A.6    Kramer, P.R.7
  • 5
    • 0029926082 scopus 로고    scopus 로고
    • TrkA, CGRP and IB4 expression in retrogradely labelled cutaneous and visceral primary sensory neurones in the rat
    • Bennett D.L., Dmietrieva N., Priestley J.V., Clary D., and McMahon S.B. TrkA, CGRP and IB4 expression in retrogradely labelled cutaneous and visceral primary sensory neurones in the rat. Neurosci Lett 206 (1996) 33-36
    • (1996) Neurosci Lett , vol.206 , pp. 33-36
    • Bennett, D.L.1    Dmietrieva, N.2    Priestley, J.V.3    Clary, D.4    McMahon, S.B.5
  • 6
    • 33644847701 scopus 로고    scopus 로고
    • A comparison between the effects of acetaminophen and celecoxib on bone fracture healing in rats
    • Bergenstock M., Min W., Simon A.M., Sabatino C., and O'Connor J.P. A comparison between the effects of acetaminophen and celecoxib on bone fracture healing in rats. J Orthop Trauma 19 (2005) 717-723
    • (2005) J Orthop Trauma , vol.19 , pp. 717-723
    • Bergenstock, M.1    Min, W.2    Simon, A.M.3    Sabatino, C.4    O'Connor, J.P.5
  • 7
    • 0033958778 scopus 로고    scopus 로고
    • Alendronate is a specific, nanomolar inhibitor of farnesyl diphosphate synthase
    • Bergstrom J., Bostedor R., Masarachia P., Reszka A., and Rodan G. Alendronate is a specific, nanomolar inhibitor of farnesyl diphosphate synthase. Arch Biochem Biophys 373 (2000) 231-241
    • (2000) Arch Biochem Biophys , vol.373 , pp. 231-241
    • Bergstrom, J.1    Bostedor, R.2    Masarachia, P.3    Reszka, A.4    Rodan, G.5
  • 8
    • 20444382797 scopus 로고    scopus 로고
    • Nonsteroidal antiinflammatory drugs and nonunion of humeral shaft fractures
    • Bhattacharyya T., Levin R., Vrahas M.S., and Solomon D.H. Nonsteroidal antiinflammatory drugs and nonunion of humeral shaft fractures. Arthritis Rheum 53 (2005) 364-367
    • (2005) Arthritis Rheum , vol.53 , pp. 364-367
    • Bhattacharyya, T.1    Levin, R.2    Vrahas, M.S.3    Solomon, D.H.4
  • 9
    • 54049133735 scopus 로고    scopus 로고
    • GDNF hyperalgesia is mediated by PLCgamma, MAPK/ERK, PI3K, CDK5 and Src family kinase signaling and dependent on the IB4-binding protein versican
    • Bogen O., Joseph E.K., Chen X., and Levine J.D. GDNF hyperalgesia is mediated by PLCgamma, MAPK/ERK, PI3K, CDK5 and Src family kinase signaling and dependent on the IB4-binding protein versican. Eur J Neurosci 28 (2008) 12-19
    • (2008) Eur J Neurosci , vol.28 , pp. 12-19
    • Bogen, O.1    Joseph, E.K.2    Chen, X.3    Levine, J.D.4
  • 10
    • 0021612066 scopus 로고
    • Production of a standard closed fracture in laboratory animal bone
    • Bonnarens F., and Einhorn T.A. Production of a standard closed fracture in laboratory animal bone. J Orthop Res 2 (1984) 97-101
    • (1984) J Orthop Res , vol.2 , pp. 97-101
    • Bonnarens, F.1    Einhorn, T.A.2
  • 11
    • 33749177293 scopus 로고    scopus 로고
    • The burden of musculoskeletal disease: a global perspective
    • Brooks P.M. The burden of musculoskeletal disease: a global perspective. Clin Rheumatol 25 (2006) 778-781
    • (2006) Clin Rheumatol , vol.25 , pp. 778-781
    • Brooks, P.M.1
  • 14
    • 51349111786 scopus 로고    scopus 로고
    • Variability in the assessment of fracture-healing in orthopaedic trauma studies
    • Corrales L.A., Morshed S., Bhandari M., and Miclau III T. Variability in the assessment of fracture-healing in orthopaedic trauma studies. J Bone Joint Surg Am 90 (2008) 1862-1868
    • (2008) J Bone Joint Surg Am , vol.90 , pp. 1862-1868
    • Corrales, L.A.1    Morshed, S.2    Bhandari, M.3    Miclau III, T.4
  • 15
    • 2642577602 scopus 로고    scopus 로고
    • Health-related quality of life and health service use among older adults with osteoarthritis
    • Dominick K.L., Ahern F.M., Gold C.H., and Heller D.A. Health-related quality of life and health service use among older adults with osteoarthritis. Arthritis Rheum 51 (2004) 326-331
    • (2004) Arthritis Rheum , vol.51 , pp. 326-331
    • Dominick, K.L.1    Ahern, F.M.2    Gold, C.H.3    Heller, D.A.4
  • 16
    • 42249086655 scopus 로고    scopus 로고
    • Cutaneous sensory neurons expressing the Mrgprd receptor sense extracellular ATP and are putative nociceptors
    • Dussor G., Zylka M.J., Anderson D.J., and McCleskey E.W. Cutaneous sensory neurons expressing the Mrgprd receptor sense extracellular ATP and are putative nociceptors. J Neurophysiol 99 (2008) 1581-1589
    • (2008) J Neurophysiol , vol.99 , pp. 1581-1589
    • Dussor, G.1    Zylka, M.J.2    Anderson, D.J.3    McCleskey, E.W.4
  • 17
    • 0031734171 scopus 로고    scopus 로고
    • The cell and molecular biology of fracture healing
    • Einhorn T.A. The cell and molecular biology of fracture healing. Clin Orthop Relat Res 355 (1998) S7-S21
    • (1998) Clin Orthop Relat Res , vol.355
    • Einhorn, T.A.1
  • 18
    • 33646201771 scopus 로고    scopus 로고
    • The science of fracture healing
    • Einhorn T.A. The science of fracture healing. J Orthop Trauma 19 (2005) S4-S6
    • (2005) J Orthop Trauma , vol.19
    • Einhorn, T.A.1
  • 19
    • 20544431746 scopus 로고    scopus 로고
    • Acute pain following musculoskeletal injuries and orthopaedic surgery: mechanisms and management
    • Ekman E.F., and Koman L.A. Acute pain following musculoskeletal injuries and orthopaedic surgery: mechanisms and management. Instr Course Lect 54 (2005) 21-33
    • (2005) Instr Course Lect , vol.54 , pp. 21-33
    • Ekman, E.F.1    Koman, L.A.2
  • 22
    • 0030844635 scopus 로고    scopus 로고
    • Involvement of prostaglandins and CGRP-dependent sensory afferents in peritoneal irritation-induced visceral pain
    • Friese N., Diop L., Chevalier E., Angel F., Riviere P.J., and Dahl S.G. Involvement of prostaglandins and CGRP-dependent sensory afferents in peritoneal irritation-induced visceral pain. Regul Pept 70 (1997) 1-7
    • (1997) Regul Pept , vol.70 , pp. 1-7
    • Friese, N.1    Diop, L.2    Chevalier, E.3    Angel, F.4    Riviere, P.J.5    Dahl, S.G.6
  • 24
    • 0012429950 scopus 로고    scopus 로고
    • Differential inhibition of fracture healing by non-selective and cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs
    • Gerstenfeld L.C., Thiede M., Seibert K., Mielke C., Phippard D., Svagr B., Cullinane D., and Einhorn T.A. Differential inhibition of fracture healing by non-selective and cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs. J Orthop Res 21 (2003) 670-675
    • (2003) J Orthop Res , vol.21 , pp. 670-675
    • Gerstenfeld, L.C.1    Thiede, M.2    Seibert, K.3    Mielke, C.4    Phippard, D.5    Svagr, B.6    Cullinane, D.7    Einhorn, T.A.8
  • 28
    • 0033194470 scopus 로고    scopus 로고
    • Early versus delayed stabilization of pediatric femur fractures: analysis of 387 patients
    • Hedequist D., Starr A.J., Wilson P., and Walker J. Early versus delayed stabilization of pediatric femur fractures: analysis of 387 patients. J Orthop Trauma 13 (1999) 490-493
    • (1999) J Orthop Trauma , vol.13 , pp. 490-493
    • Hedequist, D.1    Starr, A.J.2    Wilson, P.3    Walker, J.4
  • 29
    • 0025914202 scopus 로고
    • Effects of neonatal sympathectomy and capsaicin treatment on bone remodeling in rats
    • Hill E.L., Turner R., and Elde R. Effects of neonatal sympathectomy and capsaicin treatment on bone remodeling in rats. Neuroscience 44 (1991) 747-755
    • (1991) Neuroscience , vol.44 , pp. 747-755
    • Hill, E.L.1    Turner, R.2    Elde, R.3
  • 30
    • 0019843546 scopus 로고
    • Increase in tissue concentrations of histamine and 5-hydroxytryptamine following capsaicin treatment of newborn rats
    • Holzer P., Saria A., Skofitsch G., and Lembeck F. Increase in tissue concentrations of histamine and 5-hydroxytryptamine following capsaicin treatment of newborn rats. Life Sci 29 (1981) 1099-1105
    • (1981) Life Sci , vol.29 , pp. 1099-1105
    • Holzer, P.1    Saria, A.2    Skofitsch, G.3    Lembeck, F.4
  • 32
    • 0027311068 scopus 로고
    • Rapid proliferation of calcitonin gene-related peptide-immunoreactive nerves during healing of rat tibial fracture suggests neural involvement in bone growth and remodelling
    • Hukkanen M., Konttinen Y.T., Santavirta S., Paavolainen P., Gu X.H., Terenghi G., and Polak J.M. Rapid proliferation of calcitonin gene-related peptide-immunoreactive nerves during healing of rat tibial fracture suggests neural involvement in bone growth and remodelling. Neuroscience 54 (1993) 969-979
    • (1993) Neuroscience , vol.54 , pp. 969-979
    • Hukkanen, M.1    Konttinen, Y.T.2    Santavirta, S.3    Paavolainen, P.4    Gu, X.H.5    Terenghi, G.6    Polak, J.M.7
  • 33
    • 0035256911 scopus 로고    scopus 로고
    • The molecular dynamics of pain control
    • Hunt S.P., and Mantyh P.W. The molecular dynamics of pain control. Nat Rev Neurosci 2 (2001) 83-91
    • (2001) Nat Rev Neurosci , vol.2 , pp. 83-91
    • Hunt, S.P.1    Mantyh, P.W.2
  • 34
    • 0001337331 scopus 로고
    • Referred pain from skeletal structures
    • Inman V.T., and Saunders J.B. Referred pain from skeletal structures. J Nerve Ment Dis 99 (1944) 660-667
    • (1944) J Nerve Ment Dis , vol.99 , pp. 660-667
    • Inman, V.T.1    Saunders, J.B.2
  • 35
    • 33644844261 scopus 로고    scopus 로고
    • Absence of large-diameter sensory fibres in a nerve to the cat humerus
    • Ivanusic J.J., Mahns D.A., Sahai V., and Rowe M.J. Absence of large-diameter sensory fibres in a nerve to the cat humerus. J Anat 208 (2006) 251-255
    • (2006) J Anat , vol.208 , pp. 251-255
    • Ivanusic, J.J.1    Mahns, D.A.2    Sahai, V.3    Rowe, M.J.4
  • 36
    • 0017720392 scopus 로고
    • Pharmacologically induced selective degeneration of chemosensitive primary sensory neurones
    • Jancso G., Kiraly E., and Jancso-Gabor A. Pharmacologically induced selective degeneration of chemosensitive primary sensory neurones. Nature 270 (1977) 741-743
    • (1977) Nature , vol.270 , pp. 741-743
    • Jancso, G.1    Kiraly, E.2    Jancso-Gabor, A.3
  • 38
    • 0035855860 scopus 로고    scopus 로고
    • Molecular mechanisms of nociception
    • Julius D., and Basbaum A.I. Molecular mechanisms of nociception. Nature 413 (2001) 203-210
    • (2001) Nature , vol.413 , pp. 203-210
    • Julius, D.1    Basbaum, A.I.2
  • 39
    • 0034176506 scopus 로고    scopus 로고
    • A new animal model for assessing mechanisms and management of muscle hyperalgesia
    • Kehl L.J., Trempe T.M., and Hargreaves K.M. A new animal model for assessing mechanisms and management of muscle hyperalgesia. Pain 85 (2000) 333-343
    • (2000) Pain , vol.85 , pp. 333-343
    • Kehl, L.J.1    Trempe, T.M.2    Hargreaves, K.M.3
  • 40
    • 20044371453 scopus 로고    scopus 로고
    • Ablation of primary afferent terminals reduces nicotinic receptor expression and the nociceptive responses to nicotinic agonists in the spinal cord
    • Khan I.M., Wennerholm M., Singletary E., Polston K., Zhang L., Deerinck T., Yaksh T.L., and Taylor P. Ablation of primary afferent terminals reduces nicotinic receptor expression and the nociceptive responses to nicotinic agonists in the spinal cord. J Neurocytol 33 (2004) 543-556
    • (2004) J Neurocytol , vol.33 , pp. 543-556
    • Khan, I.M.1    Wennerholm, M.2    Singletary, E.3    Polston, K.4    Zhang, L.5    Deerinck, T.6    Yaksh, T.L.7    Taylor, P.8
  • 41
    • 33744539903 scopus 로고    scopus 로고
    • Osteoarthritis and joint pain
    • Kidd B.L. Osteoarthritis and joint pain. Pain 123 (2006) 6-9
    • (2006) Pain , vol.123 , pp. 6-9
    • Kidd, B.L.1
  • 42
    • 34848824654 scopus 로고    scopus 로고
    • Morphine treatment accelerates sarcoma-induced bone pain, bone loss, and spontaneous fracture in a murine model of bone cancer
    • King T., Vardanyan A., Majuta L., Melemedjian O., Nagle R., Cress A.E., Vanderah T.W., Lai J., and Porreca F. Morphine treatment accelerates sarcoma-induced bone pain, bone loss, and spontaneous fracture in a murine model of bone cancer. Pain 132 (2007) 154-168
    • (2007) Pain , vol.132 , pp. 154-168
    • King, T.1    Vardanyan, A.2    Majuta, L.3    Melemedjian, O.4    Nagle, R.5    Cress, A.E.6    Vanderah, T.W.7    Lai, J.8    Porreca, F.9
  • 43
    • 0033769270 scopus 로고    scopus 로고
    • Effects of eletriptan on the peptidergic innervation of the cerebral dura mater and trigeminal ganglion, and on the expression of c-fos and c-jun in the trigeminal complex of the rat in an experimental migraine model
    • Knyihar-Csillik E., Tajti J., Csillik A.E., Chadaide Z., Mihaly A., and Vecsei L. Effects of eletriptan on the peptidergic innervation of the cerebral dura mater and trigeminal ganglion, and on the expression of c-fos and c-jun in the trigeminal complex of the rat in an experimental migraine model. Eur J Neurosci 12 (2000) 3991-4002
    • (2000) Eur J Neurosci , vol.12 , pp. 3991-4002
    • Knyihar-Csillik, E.1    Tajti, J.2    Csillik, A.E.3    Chadaide, Z.4    Mihaly, A.5    Vecsei, L.6
  • 44
    • 28544446921 scopus 로고    scopus 로고
    • Pharmacologic agents in fracture healing
    • Koester M.C., and Spindler K.P. Pharmacologic agents in fracture healing. Clin Sports Med 25 (2006) 63-73
    • (2006) Clin Sports Med , vol.25 , pp. 63-73
    • Koester, M.C.1    Spindler, K.P.2
  • 47
    • 0034028782 scopus 로고    scopus 로고
    • Factors that modify the association between knee pain and mobility limitation in older women: the Women's Health and Aging Study
    • Lamb S.E., Guralnik J.M., Buchner D.M., Ferrucci L.M., Hochberg M.C., Simonsick E.M., and Fried L.P. Factors that modify the association between knee pain and mobility limitation in older women: the Women's Health and Aging Study. Ann Rheum Dis 59 (2000) 331-337
    • (2000) Ann Rheum Dis , vol.59 , pp. 331-337
    • Lamb, S.E.1    Guralnik, J.M.2    Buchner, D.M.3    Ferrucci, L.M.4    Hochberg, M.C.5    Simonsick, E.M.6    Fried, L.P.7
  • 49
    • 0022980857 scopus 로고
    • Contribution of sensory afferents and sympathetic efferents to joint injury in experimental arthritis
    • Levine J.D., Dardick S.J., Roizen M.F., Helms C., and Basbaum A.I. Contribution of sensory afferents and sympathetic efferents to joint injury in experimental arthritis. J Neurosci 6 (1986) 3423-3429
    • (1986) J Neurosci , vol.6 , pp. 3423-3429
    • Levine, J.D.1    Dardick, S.J.2    Roizen, M.F.3    Helms, C.4    Basbaum, A.I.5
  • 50
    • 0038715490 scopus 로고    scopus 로고
    • The costs of musculoskeletal disease: health needs assessment and health economics
    • Lubeck D.P. The costs of musculoskeletal disease: health needs assessment and health economics. Best Pract Res Clin Rheumatol 17 (2003) 529-539
    • (2003) Best Pract Res Clin Rheumatol , vol.17 , pp. 529-539
    • Lubeck, D.P.1
  • 51
    • 38949104188 scopus 로고    scopus 로고
    • The coming acceleration of global population ageing
    • Lutz W., Sanderson W., and Scherbov S. The coming acceleration of global population ageing. Nature 451 (2008) 716-719
    • (2008) Nature , vol.451 , pp. 716-719
    • Lutz, W.1    Sanderson, W.2    Scherbov, S.3
  • 53
    • 12344331261 scopus 로고    scopus 로고
    • Opioid use by patients in an orthopedics spine clinic
    • Mahowald M.L., Singh J.A., and Majeski P. Opioid use by patients in an orthopedics spine clinic. Arthritis Rheum 52 (2005) 312-321
    • (2005) Arthritis Rheum , vol.52 , pp. 312-321
    • Mahowald, M.L.1    Singh, J.A.2    Majeski, P.3
  • 55
    • 16644376326 scopus 로고    scopus 로고
    • Characterization of a closed femur fracture model in mice
    • Manigrasso M.B., and O'Connor J.P. Characterization of a closed femur fracture model in mice. J Orthop Trauma 18 (2004) 687-695
    • (2004) J Orthop Trauma , vol.18 , pp. 687-695
    • Manigrasso, M.B.1    O'Connor, J.P.2
  • 56
    • 35448929372 scopus 로고    scopus 로고
    • Organization of a unique net-like meshwork of CGRP+ sensory fibers in the mouse periosteum: implications for the generation and maintenance of bone fracture pain
    • Martin C.D., Jimenez-Andrade J.M., Ghilardi J.R., and Mantyh P.W. Organization of a unique net-like meshwork of CGRP+ sensory fibers in the mouse periosteum: implications for the generation and maintenance of bone fracture pain. Neurosci Lett 427 (2007) 148-152
    • (2007) Neurosci Lett , vol.427 , pp. 148-152
    • Martin, C.D.1    Jimenez-Andrade, J.M.2    Ghilardi, J.R.3    Mantyh, P.W.4
  • 57
    • 4344599524 scopus 로고    scopus 로고
    • Pediatric orthopaedic surgery pain management
    • McCann H.L., and Stanitski D.F. Pediatric orthopaedic surgery pain management. J Pediatr Orthop 24 (2004) 581-586
    • (2004) J Pediatr Orthop , vol.24 , pp. 581-586
    • McCann, H.L.1    Stanitski, D.F.2
  • 58
    • 0026558207 scopus 로고
    • Effect of topical capsaicin in the therapy of painful osteoarthritis of the hands
    • McCarthy G.M., and McCarty D.J. Effect of topical capsaicin in the therapy of painful osteoarthritis of the hands. J Rheumatol 19 (1992) 604-607
    • (1992) J Rheumatol , vol.19 , pp. 604-607
    • McCarthy, G.M.1    McCarty, D.J.2
  • 59
    • 58149216630 scopus 로고    scopus 로고
    • Chronic pain and obesity in elderly people: results from the Einstein Aging Study
    • McCarthy L.H., Bigal M.E., Katz M., Derby C., and Lipton R.B. Chronic pain and obesity in elderly people: results from the Einstein Aging Study. J Am Geriatr Soc 57 (2009) 115-119
    • (2009) J Am Geriatr Soc , vol.57 , pp. 115-119
    • McCarthy, L.H.1    Bigal, M.E.2    Katz, M.3    Derby, C.4    Lipton, R.B.5
  • 60
    • 0034489458 scopus 로고    scopus 로고
    • The analgesic efficacy of topical capsaicin is enhanced by glyceryl trinitrate in painful osteoarthritis: a randomized, double blind, placebo controlled study
    • McCleane G. The analgesic efficacy of topical capsaicin is enhanced by glyceryl trinitrate in painful osteoarthritis: a randomized, double blind, placebo controlled study. Eur J Pain 4 (2000) 355-360
    • (2000) Eur J Pain , vol.4 , pp. 355-360
    • McCleane, G.1
  • 61
    • 0028289478 scopus 로고
    • Expression and coexpression of Trk receptors in subpopulations of adult primary sensory neurons projecting to identified peripheral targets
    • McMahon S.B., Armanini M.P., Ling L.H., and Phillips H.S. Expression and coexpression of Trk receptors in subpopulations of adult primary sensory neurons projecting to identified peripheral targets. Neuron 12 (1994) 1161-1171
    • (1994) Neuron , vol.12 , pp. 1161-1171
    • McMahon, S.B.1    Armanini, M.P.2    Ling, L.H.3    Phillips, H.S.4
  • 62
    • 0034639346 scopus 로고    scopus 로고
    • Cholinergic innervation in adult rat cerebral cortex: a quantitative immunocytochemical description
    • Mechawar N., Cozzari C., and Descarries L. Cholinergic innervation in adult rat cerebral cortex: a quantitative immunocytochemical description. J Comp Neurol 428 (2000) 305-318
    • (2000) J Comp Neurol , vol.428 , pp. 305-318
    • Mechawar, N.1    Cozzari, C.2    Descarries, L.3
  • 64
    • 0026620150 scopus 로고
    • Neonatal capsaicin treatment prevents the development of the thermal hyperalgesia produced in a model of neuropathic pain in the rat
    • Meller S.T., Gebhart G.F., and Maves T.J. Neonatal capsaicin treatment prevents the development of the thermal hyperalgesia produced in a model of neuropathic pain in the rat. Pain 51 (1992) 317-321
    • (1992) Pain , vol.51 , pp. 317-321
    • Meller, S.T.1    Gebhart, G.F.2    Maves, T.J.3
  • 65
    • 0032085417 scopus 로고    scopus 로고
    • Unreamed retrograde intramedullary nailing of fractures of the femoral shaft
    • Moed B.R., Watson J.T., Cramer K.E., Karges D.E., and Teefey J.S. Unreamed retrograde intramedullary nailing of fractures of the femoral shaft. J Orthop Trauma 12 (1998) 334-342
    • (1998) J Orthop Trauma , vol.12 , pp. 334-342
    • Moed, B.R.1    Watson, J.T.2    Cramer, K.E.3    Karges, D.E.4    Teefey, J.S.5
  • 66
    • 0028791387 scopus 로고
    • Presence or absence of TrkA protein distinguishes subsets of small sensory neurons with unique cytochemical characteristics and dorsal horn projections
    • Molliver D.C., Radeke M.J., Feinstein S.C., and Snider W.D. Presence or absence of TrkA protein distinguishes subsets of small sensory neurons with unique cytochemical characteristics and dorsal horn projections. J Comp Neurol 361 (1995) 404-416
    • (1995) J Comp Neurol , vol.361 , pp. 404-416
    • Molliver, D.C.1    Radeke, M.J.2    Feinstein, S.C.3    Snider, W.D.4
  • 70
    • 0022385211 scopus 로고
    • Influence of fixation and decalcification on the immunohistochemical staining of cell-specific markers in paraffin-embedded human bone biopsies
    • Mullink H., Henzen-Logmans S.C., Tadema T.M., Mol J.J., and Meijer C.J. Influence of fixation and decalcification on the immunohistochemical staining of cell-specific markers in paraffin-embedded human bone biopsies. J Histochem Cytochem 33 (1985) 1103-1109
    • (1985) J Histochem Cytochem , vol.33 , pp. 1103-1109
    • Mullink, H.1    Henzen-Logmans, S.C.2    Tadema, T.M.3    Mol, J.J.4    Meijer, C.J.5
  • 71
    • 33750697333 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drug-induced fracture nonunion: an inhibition of angiogenesis?
    • Murnaghan M., Li G., and Marsh D.R. Nonsteroidal anti-inflammatory drug-induced fracture nonunion: an inhibition of angiogenesis?. J Bone Joint Surg Am 88 Suppl 3 (2006) 140-147
    • (2006) J Bone Joint Surg Am 88 Suppl , vol.3 , pp. 140-147
    • Murnaghan, M.1    Li, G.2    Marsh, D.R.3
  • 72
    • 0020512264 scopus 로고
    • The termination of primary afferents within the dorsal horn: evidence for rearrangement following capsaicin treatment
    • Nagy J.I., and Hunt S.P. The termination of primary afferents within the dorsal horn: evidence for rearrangement following capsaicin treatment. J Comp Neurol 218 (1983) 145-158
    • (1983) J Comp Neurol , vol.218 , pp. 145-158
    • Nagy, J.I.1    Hunt, S.P.2
  • 73
    • 0019376799 scopus 로고
    • Biochemical and anatomical observations on the degeneration of peptide-containing primary afferent neurons after neonatal capsaicin
    • Nagy J.I., Hunt S.P., Iversen L.L., and Emson P.C. Biochemical and anatomical observations on the degeneration of peptide-containing primary afferent neurons after neonatal capsaicin. Neuroscience 6 (1981) 1923-1934
    • (1981) Neuroscience , vol.6 , pp. 1923-1934
    • Nagy, J.I.1    Hunt, S.P.2    Iversen, L.L.3    Emson, P.C.4
  • 74
    • 0020600463 scopus 로고
    • Dose-dependent effects of capsaicin on primary sensory neurons in the neonatal rat
    • Nagy J.I., Iversen L.L., Goedert M., Chapman D., and Hunt S.P. Dose-dependent effects of capsaicin on primary sensory neurons in the neonatal rat. J Neurosci 3 (1983) 399-406
    • (1983) J Neurosci , vol.3 , pp. 399-406
    • Nagy, J.I.1    Iversen, L.L.2    Goedert, M.3    Chapman, D.4    Hunt, S.P.5
  • 75
    • 34250217010 scopus 로고    scopus 로고
    • Intrathecal administration of ATP produces long-lasting allodynia in rats: differential mechanisms in the phase of the induction and maintenance
    • Nakagawa T., Wakamatsu K., Zhang N., Maeda S., Minami M., Satoh M., and Kaneko S. Intrathecal administration of ATP produces long-lasting allodynia in rats: differential mechanisms in the phase of the induction and maintenance. Neuroscience 147 (2007) 445-455
    • (2007) Neuroscience , vol.147 , pp. 445-455
    • Nakagawa, T.1    Wakamatsu, K.2    Zhang, N.3    Maeda, S.4    Minami, M.5    Satoh, M.6    Kaneko, S.7
  • 78
    • 0023760575 scopus 로고
    • The healing of closed tibial shaft fractures
    • Oni O.A., Hui A., and Gregg P.J. The healing of closed tibial shaft fractures. J Bone Joint Surg Br 70-B (1988) 787-790
    • (1988) J Bone Joint Surg Br , vol.70 -B , pp. 787-790
    • Oni, O.A.1    Hui, A.2    Gregg, P.J.3
  • 79
    • 0037683191 scopus 로고    scopus 로고
    • The dorsal portion of the lumbar intervertebral disc is innervated primarily by small peptide-containing dorsal root ganglion neurons in rats
    • Ozawa T., Aoki Y., Ohtori S., Takahashi K., Chiba T., Ino H., and Moriya H. The dorsal portion of the lumbar intervertebral disc is innervated primarily by small peptide-containing dorsal root ganglion neurons in rats. Neurosci Lett 344 (2003) 65-67
    • (2003) Neurosci Lett , vol.344 , pp. 65-67
    • Ozawa, T.1    Aoki, Y.2    Ohtori, S.3    Takahashi, K.4    Chiba, T.5    Ino, H.6    Moriya, H.7
  • 80
    • 33749516681 scopus 로고    scopus 로고
    • The degenerated lumbar intervertebral disc is innervated primarily by peptide-containing sensory nerve fibers in humans
    • Ozawa T., Ohtori S., Inoue G., Aoki Y., Moriya H., and Takahashi K. The degenerated lumbar intervertebral disc is innervated primarily by peptide-containing sensory nerve fibers in humans. Spine 31 (2006) 2418-2422
    • (2006) Spine , vol.31 , pp. 2418-2422
    • Ozawa, T.1    Ohtori, S.2    Inoue, G.3    Aoki, Y.4    Moriya, H.5    Takahashi, K.6
  • 81
    • 36248954733 scopus 로고    scopus 로고
    • Management of the multiply injured patient
    • Rockwood C.A. (Ed), Lippincott Williams & Wilkins, Philadelphia
    • Pape H.-C., and Giannoudis P. Management of the multiply injured patient. In: Rockwood C.A. (Ed). Rockwood and Green's fractures in adults, Vol. 1 (2006), Lippincott Williams & Wilkins, Philadelphia 59-93
    • (2006) Rockwood and Green's fractures in adults, Vol. 1 , pp. 59-93
    • Pape, H.-C.1    Giannoudis, P.2
  • 82
    • 34250311596 scopus 로고    scopus 로고
    • Preliminary study on the effect of parenteral naloxone, alone and in association with calcium gluconate, on bone healing in an ovine "drill hole" model system
    • Petrizzi L., Mariscoli M., Valbonetti L., Varasano V., Langhoff J.D., and Von Rechenberg B. Preliminary study on the effect of parenteral naloxone, alone and in association with calcium gluconate, on bone healing in an ovine "drill hole" model system. BMC Musculoskelet Disord 8 (2007) 43
    • (2007) BMC Musculoskelet Disord , vol.8 , pp. 43
    • Petrizzi, L.1    Mariscoli, M.2    Valbonetti, L.3    Varasano, V.4    Langhoff, J.D.5    Von Rechenberg, B.6
  • 85
    • 0022491865 scopus 로고
    • Altered distribution of dorsal root fibers in the rat following neonatal capsaicin treatment
    • Rethelyi M., Salim M.Z., and Jancso G. Altered distribution of dorsal root fibers in the rat following neonatal capsaicin treatment. Neuroscience 18 (1986) 749-761
    • (1986) Neuroscience , vol.18 , pp. 749-761
    • Rethelyi, M.1    Salim, M.Z.2    Jancso, G.3
  • 86
    • 34548499678 scopus 로고    scopus 로고
    • Cohort differences in adult obesity in the United States: 1982-2002
    • Reynolds S.L., and Himes C.L. Cohort differences in adult obesity in the United States: 1982-2002. J Aging Health 19 (2007) 831-850
    • (2007) J Aging Health , vol.19 , pp. 831-850
    • Reynolds, S.L.1    Himes, C.L.2
  • 87
    • 0035100034 scopus 로고    scopus 로고
    • Sex differences in musculoskeletal pain
    • Rollman G.B., and Lautenbacher S. Sex differences in musculoskeletal pain. Clin J Pain 17 (2001) 20-24
    • (2001) Clin J Pain , vol.17 , pp. 20-24
    • Rollman, G.B.1    Lautenbacher, S.2
  • 88
    • 34548419589 scopus 로고    scopus 로고
    • Osteoarthritis and functional disability: results of a cross sectional study among primary care patients in Germany
    • Rosemann T., Laux G., and Kuehlein T. Osteoarthritis and functional disability: results of a cross sectional study among primary care patients in Germany. BMC Musculoskelet Disord 8 (2007) 79
    • (2007) BMC Musculoskelet Disord , vol.8 , pp. 79
    • Rosemann, T.1    Laux, G.2    Kuehlein, T.3
  • 89
    • 0035411119 scopus 로고    scopus 로고
    • A phenomenological study of pain following fractured shaft of femur
    • Santy J., and Mackintosh C. A phenomenological study of pain following fractured shaft of femur. J Clin Nurs 10 (2001) 521-527
    • (2001) J Clin Nurs , vol.10 , pp. 521-527
    • Santy, J.1    Mackintosh, C.2
  • 90
    • 39649117970 scopus 로고    scopus 로고
    • Physical activity as a mediator of the impact of chronic conditions on quality of life in older adults
    • Sawatzky R., Liu-Ambrose T., Miller W.C., and Marra C.A. Physical activity as a mediator of the impact of chronic conditions on quality of life in older adults. Health Qual Life Outcomes 5 (2007) 68
    • (2007) Health Qual Life Outcomes , vol.5 , pp. 68
    • Sawatzky, R.1    Liu-Ambrose, T.2    Miller, W.C.3    Marra, C.A.4
  • 93
    • 0025323681 scopus 로고
    • Neonatal capsaicin treatment induces invasion of the substantia gelatinosa by the terminal arborizations of hair follicle afferents in the rat dorsal horn
    • Shortland P., Molander C., Woolf C.J., and Fitzgerald M. Neonatal capsaicin treatment induces invasion of the substantia gelatinosa by the terminal arborizations of hair follicle afferents in the rat dorsal horn. J Comp Neurol 296 (1990) 23-31
    • (1990) J Comp Neurol , vol.296 , pp. 23-31
    • Shortland, P.1    Molander, C.2    Woolf, C.J.3    Fitzgerald, M.4
  • 94
    • 0035211454 scopus 로고    scopus 로고
    • Acute sensitization by NGF of the response of small-diameter sensory neurons to capsaicin
    • Shu X., and Mendell L.M. Acute sensitization by NGF of the response of small-diameter sensory neurons to capsaicin. J Neurophysiol 86 (2001) 2931-2938
    • (2001) J Neurophysiol , vol.86 , pp. 2931-2938
    • Shu, X.1    Mendell, L.M.2
  • 95
    • 0035999429 scopus 로고    scopus 로고
    • Cyclo-oxygenase 2 function is essential for bone fracture healing
    • Simon A.M., Manigrasso M.B., and O'Connor J.P. Cyclo-oxygenase 2 function is essential for bone fracture healing. J Bone Miner Res 17 (2002) 963-976
    • (2002) J Bone Miner Res , vol.17 , pp. 963-976
    • Simon, A.M.1    Manigrasso, M.B.2    O'Connor, J.P.3
  • 96
    • 33847665704 scopus 로고    scopus 로고
    • Dose and time-dependent effects of cyclooxygenase-2 inhibition on fracture-healing
    • Simon A.M., and O'Connor J.P. Dose and time-dependent effects of cyclooxygenase-2 inhibition on fracture-healing. J Bone Joint Surg Am 89 (2007) 500-511
    • (2007) J Bone Joint Surg Am , vol.89 , pp. 500-511
    • Simon, A.M.1    O'Connor, J.P.2
  • 97
    • 0024255671 scopus 로고
    • Femoral shaft fracture in 265 children. Log-normal correlation with age of speed of healing
    • Skak S.V., and Jensen T.T. Femoral shaft fracture in 265 children. Log-normal correlation with age of speed of healing. Acta Orthop Scand 59 (1988) 704-707
    • (1988) Acta Orthop Scand , vol.59 , pp. 704-707
    • Skak, S.V.1    Jensen, T.T.2
  • 98
    • 32244449062 scopus 로고    scopus 로고
    • Physical activity and aging
    • Stewart K.J. Physical activity and aging. Ann N Y Acad Sci 1055 (2005) 193-206
    • (2005) Ann N Y Acad Sci , vol.1055 , pp. 193-206
    • Stewart, K.J.1
  • 99
    • 0034256565 scopus 로고    scopus 로고
    • Mechanical allodynia caused by intraplantar injection of P2X receptor agonist in rats: involvement of heteromeric P2X2/3 receptor signaling in capsaicin-insensitive primary afferent neurons
    • Tsuda M., Koizumi S., Kita A., Shigemoto Y., Ueno S., and Inoue K. Mechanical allodynia caused by intraplantar injection of P2X receptor agonist in rats: involvement of heteromeric P2X2/3 receptor signaling in capsaicin-insensitive primary afferent neurons. J Neurosci 20 (2000) RC90
    • (2000) J Neurosci , vol.20
    • Tsuda, M.1    Koizumi, S.2    Kita, A.3    Shigemoto, Y.4    Ueno, S.5    Inoue, K.6
  • 100
    • 33747306680 scopus 로고    scopus 로고
    • Differential distribution of vanilloid receptors in the primary sensory neurons projecting to the dorsal skin and muscles
    • Tsukagoshi M., Goris R.C., and Funakoshi K. Differential distribution of vanilloid receptors in the primary sensory neurons projecting to the dorsal skin and muscles. Histochem Cell Biol 126 (2006) 343-352
    • (2006) Histochem Cell Biol , vol.126 , pp. 343-352
    • Tsukagoshi, M.1    Goris, R.C.2    Funakoshi, K.3
  • 101
    • 63849133559 scopus 로고    scopus 로고
    • Overweight and health problems of the lower extremities: osteoarthritis, pain and disability
    • Tukker A., Visscher T., and Picavet H. Overweight and health problems of the lower extremities: osteoarthritis, pain and disability. Public Health Nutr 12 (2009) 359-368
    • (2009) Public Health Nutr , vol.12 , pp. 359-368
    • Tukker, A.1    Visscher, T.2    Picavet, H.3
  • 103
    • 67949106833 scopus 로고    scopus 로고
    • A randomized phase 2 study to evaluate intra-articular injection of a highly purified capsaicin formulation for treatment of painful osteoarthritis of the knee
    • Glasgow, Scotland, UK
    • Wong G.Y., Leszczyszyn J., Kurek J., and Yu K. A randomized phase 2 study to evaluate intra-articular injection of a highly purified capsaicin formulation for treatment of painful osteoarthritis of the knee. 12th World Congress on Pain (2008) Glasgow, Scotland, UK
    • (2008) 12th World Congress on Pain
    • Wong, G.Y.1    Leszczyszyn, J.2    Kurek, J.3    Yu, K.4
  • 104
    • 0141920503 scopus 로고    scopus 로고
    • Burden of major musculoskeletal conditions
    • Woolf A.D., and Pfleger B. Burden of major musculoskeletal conditions. Bull World Health Organ 81 (2003) 646-656
    • (2003) Bull World Health Organ , vol.81 , pp. 646-656
    • Woolf, A.D.1    Pfleger, B.2
  • 105
    • 33644847909 scopus 로고    scopus 로고
    • Burden of osteoporosis and fractures in developing countries
    • Woolf A.D., and Pfleger B. Burden of osteoporosis and fractures in developing countries. Curr Osteoporos Rep 3 (2005) 84-91
    • (2005) Curr Osteoporos Rep , vol.3 , pp. 84-91
    • Woolf, A.D.1    Pfleger, B.2
  • 106
    • 33846426870 scopus 로고    scopus 로고
    • Sympathetic sprouting near sensory neurons after nerve injury occurs preferentially on spontaneously active cells and is reduced by early nerve block
    • Xie W., Strong J.A., Li H., and Zhang J.M. Sympathetic sprouting near sensory neurons after nerve injury occurs preferentially on spontaneously active cells and is reduced by early nerve block. J Neurophysiol 97 (2007) 492-502
    • (2007) J Neurophysiol , vol.97 , pp. 492-502
    • Xie, W.1    Strong, J.A.2    Li, H.3    Zhang, J.M.4
  • 107
    • 0342311932 scopus 로고
    • Orthopaedic pain after trauma
    • Wall P.D., and Melzack R. (Eds), Churchill Livingstone, Edinburgh
    • Yates D., and Smith M. Orthopaedic pain after trauma. In: Wall P.D., and Melzack R. (Eds). Textbook of pain (1994), Churchill Livingstone, Edinburgh 409-421
    • (1994) Textbook of pain , pp. 409-421
    • Yates, D.1    Smith, M.2
  • 108
    • 33846889518 scopus 로고    scopus 로고
    • Naltrexone accelerates healing without compromise of adhesion complexes in normal and diabetic corneal epithelium
    • Zagon I.S., Sassani J.W., Myers R.L., and McLaughlin P.J. Naltrexone accelerates healing without compromise of adhesion complexes in normal and diabetic corneal epithelium. Brain Res Bull 72 (2007) 18-24
    • (2007) Brain Res Bull , vol.72 , pp. 18-24
    • Zagon, I.S.1    Sassani, J.W.2    Myers, R.L.3    McLaughlin, P.J.4
  • 109
    • 3042780039 scopus 로고    scopus 로고
    • Effect of blockade of nerve growth factor and tumor necrosis factor on pain behaviors after plantar incision
    • Zahn P.K., Subieta A., Park S.S., and Brennan T.J. Effect of blockade of nerve growth factor and tumor necrosis factor on pain behaviors after plantar incision. J Pain 5 (2004) 157-163
    • (2004) J Pain , vol.5 , pp. 157-163
    • Zahn, P.K.1    Subieta, A.2    Park, S.S.3    Brennan, T.J.4
  • 110
    • 11344251617 scopus 로고    scopus 로고
    • Topographically distinct epidermal nociceptive circuits revealed by axonal tracers targeted to Mrgprd
    • Zylka M.J., Rice F.L., and Anderson D.J. Topographically distinct epidermal nociceptive circuits revealed by axonal tracers targeted to Mrgprd. Neuron 45 (2005) 17-25
    • (2005) Neuron , vol.45 , pp. 17-25
    • Zylka, M.J.1    Rice, F.L.2    Anderson, D.J.3


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