Enhanced angiogenesis mediated by vascular endothelial growth factor plasmid-loaded thermo-responsive amphiphilic polymer in a rat myocardial infarction model

Journal of Controlled Release

Volumn 138, Issue 2, 2009, Pages 168-176

  Kwon, Jin Sook ^a   Park, In Kyu ^a,e   Cho, Ae Shin ^a   Shin, Sun Mi ^a   Hong, Moon Hwa ^a   Jeong, Seo Yeon ^a   Kim, Yong Sook ^a   Min, Jung Joon ^a,e   Jeong, Myung Ho ^a   Kim, Won Jong ^b   Jo, Seongbong ^c   Pun, Suzie H ^d   Cho, Jeong Gwan ^a   Park, Jong Chun ^a   Kang, Jung Chaee ^a   Ahn, Youngkeun ^a  

^a Chonnam National University Medical School   (South Korea)

^b Pohang University of Science and Technology (POSTECH)   (South Korea)

^c UNIVERSITY OF MISSISSIPPI   (United States)

^d University of Washington   (United States)

^e Gwangju Institute of Science and Technology (GIST)   (South Korea)

Author keywords

Angiogenesis; Local gene transfer; Myocardial infarction; Temperature responsive amphiphilic polymer

Indexed keywords

3-DIMENSIONAL STRUCTURES; AMPHIPHILIC; AMPHIPHILIC POLYMERS; ANGIOGENESIS; CAPILLARY DENSITY; CONTROLLED RELEASE; ENHANCED GENE EXPRESSION; EXPRESSION PROFILE; HISTOLOGICAL ANALYSIS; INFLAMMATORY CELLS; LOCAL GENE TRANSFER; LUCIFERASE ASSAYS; LUCIFERASE GENES; MOUSE HEART; MYOCARDIAL INFARCTION; NAKED PLASMID; OPTICAL IMAGING; POLYMERIC HYDROGELS; PROTEIN CONCENTRATIONS; TEMPERATURE-RESPONSIVE AMPHIPHILIC POLYMER; THERAPEUTIC GENES; THERMO-RESPONSIVE; THERMORESPONSIVE POLYMER; VASCULAR ENDOTHELIAL GROWTH FACTOR; VESSEL FORMATION;

BIOACTIVITY; BIODEGRADABLE POLYMERS; GENE EXPRESSION; GENE TRANSFER; MUSCLE; NUCLEIC ACIDS; PEPTIDES; SELF ASSEMBLY;

HYDROGELS;

COPOLYMER; LUCIFERASE; MULTI BLOCK COPOLYMER 2; PLASMID VECTOR; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC GENE THERAPY; ARTICLE; CAPILLARY DENSITY; CONTROLLED STUDY; GENE EXPRESSION; GENE LOCATION; HEART INFARCTION; HISTOLOGY; HYDROGEL; MALE; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; BLOTTING, WESTERN; DISEASE MODELS, ANIMAL; DRUG CARRIERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE TRANSFER TECHNIQUES; HUMANS; HYDROGELS; IMMUNOHISTOCHEMISTRY; LUCIFERASES; MALE; MYOCARDIAL INFARCTION; MYOCARDIUM; NEOVASCULARIZATION, PHYSIOLOGIC; PLASMIDS; POLYMERS; RATS; RATS, SPRAGUE-DAWLEY; SURFACE-ACTIVE AGENTS; TEMPERATURE; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 67849124168     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2009.05.023     Document Type: Article

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