메뉴 건너뛰기




Volumn 17, Issue 8, 2009, Pages 1056-1062

Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: The DAMAGE study

(20)  Reiling, Erwin a   van Vliet Ostaptchouk, Jana V b   van't Riet, Esther c   van Haeften, Timon W d   Arp, Pascal A e   Hansen, Torben f   Kremer, Dennis a   Groenewoud, Marlous J a   van Hove, Els C a   Romijn, Johannes A a   Smit, Jan W A a   Nijpels, Giel c   Heine, Robert J c   Uitterlinden, André G e   Pedersen, Oluf f,g,h   Slagboom, P Eline a   Maassen, Johannes A a,c   Hofker, Marten H b   't Hart, Leen M a   Dekker, Jacqueline M c  


Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID TRANSFER RNA LIGASE; GENE PRODUCT; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN 3; INITIATION FACTOR 2; INITIATION FACTOR 3; MITOCHONDRIAL PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEIN DARS2; PROTEIN IARS2; PROTEIN MTO1; PROTEIN PPRC1; PROTEIN TARS2; PROTEIN TFAM; PROTEIN TRMU; SIRTUIN 3; SIRTUIN 4; UNCLASSIFIED DRUG;

EID: 67749137221     PISSN: 10184813     EISSN: 14765438     Source Type: Journal    
DOI: 10.1038/ejhg.2009.4     Document Type: Article
Times cited : (11)

References (47)
  • 1
    • 0026906885 scopus 로고
    • Mutation in mitochondrial tRNA(Leu)(UUR) gene in a large pedigree with maternally transmitted type II diabetes mellitus and deafness
    • van den Ouweland JM, Lemkes HH, Ruitenbeek W et al: Mutation in mitochondrial tRNA(Leu)(UUR) gene in a large pedigree with maternally transmitted type II diabetes mellitus and deafness. Nat Genet 1992; 1: 368-371.
    • (1992) Nat Genet , vol.1 , pp. 368-371
    • van den Ouweland, J.M.1    Lemkes, H.H.2    Ruitenbeek, W.3
  • 2
    • 33751274538 scopus 로고    scopus 로고
    • Maassen JA, t Hart LM, Janssen GM, Reiling E, Romijn JA, Lemkes HH: Mitochondrial diabetes and its lessons for common Type 2 diabetes. Biochem Soc Trans 2006; 34 (Pt 5): 819-823.
    • Maassen JA, t Hart LM, Janssen GM, Reiling E, Romijn JA, Lemkes HH: Mitochondrial diabetes and its lessons for common Type 2 diabetes. Biochem Soc Trans 2006; 34 (Pt 5): 819-823.
  • 3
    • 20044392682 scopus 로고    scopus 로고
    • Evidence that the mitochondrial leucyl tRNA synthetase (LARS2) gene represents a novel type 2 diabetes susceptibility gene
    • 't Hart LM, Hansen T, Rietveld I et al: Evidence that the mitochondrial leucyl tRNA synthetase (LARS2) gene represents a novel type 2 diabetes susceptibility gene. Diabetes 2005; 54: 1892-1895.
    • (2005) Diabetes , vol.54 , pp. 1892-1895
    • 't Hart, L.M.1    Hansen, T.2    Rietveld, I.3
  • 4
    • 0036788293 scopus 로고    scopus 로고
    • Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes
    • Kelley DE, He J, Menshikova EV, Ritov VB: Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Diabetes 2002; 51: 2944-2950.
    • (2002) Diabetes , vol.51 , pp. 2944-2950
    • Kelley, D.E.1    He, J.2    Menshikova, E.V.3    Ritov, V.B.4
  • 5
    • 0038054341 scopus 로고    scopus 로고
    • PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
    • Mootha VK, Lindgren CM, Eriksson KF et al: PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet 2003; 34: 267-273.
    • (2003) Nat Genet , vol.34 , pp. 267-273
    • Mootha, V.K.1    Lindgren, C.M.2    Eriksson, K.F.3
  • 6
    • 33646362551 scopus 로고    scopus 로고
    • Systematic identification of human mitochondrial disease genes through integrative genomics
    • Calvo S, Jain M, Xie X et al: Systematic identification of human mitochondrial disease genes through integrative genomics. Nat Genet 2006; 38: 576-582.
    • (2006) Nat Genet , vol.38 , pp. 576-582
    • Calvo, S.1    Jain, M.2    Xie, X.3
  • 7
    • 27944473305 scopus 로고    scopus 로고
    • Mitochondrial polymorphisms and susceptibility to type 2 diabetes-related traits in Finns
    • Mohlke KL, Jackson AU, Scott LJ et al: Mitochondrial polymorphisms and susceptibility to type 2 diabetes-related traits in Finns. Hum Genet 2005; 118: 245-254.
    • (2005) Hum Genet , vol.118 , pp. 245-254
    • Mohlke, K.L.1    Jackson, A.U.2    Scott, L.J.3
  • 8
    • 33745273048 scopus 로고    scopus 로고
    • Comprehensive association testing of common mitochondrial DNA variation in metabolic disease
    • Saxena R, de Bakker PI, Singer K et al: Comprehensive association testing of common mitochondrial DNA variation in metabolic disease. Am J Hum Genet 2006; 79: 54-61.
    • (2006) Am J Hum Genet , vol.79 , pp. 54-61
    • Saxena, R.1    de Bakker, P.I.2    Singer, K.3
  • 9
    • 0038206737 scopus 로고    scopus 로고
    • Growing evidence for diabetes susceptibility genes from genome scan data
    • McCarthy MI: Growing evidence for diabetes susceptibility genes from genome scan data. Curr Diab Rep 2003; 3: 159-167.
    • (2003) Curr Diab Rep , vol.3 , pp. 159-167
    • McCarthy, M.I.1
  • 10
    • 8444228909 scopus 로고    scopus 로고
    • A cluster of metabolic defects caused by mutation in a mitochondrial tRNA
    • Wilson FH, Hariri A, Farhi A et al: A cluster of metabolic defects caused by mutation in a mitochondrial tRNA. Science 2004; 306 1190-1194.
    • (2004) Science , vol.306 , pp. 1190-1194
    • Wilson, F.H.1    Hariri, A.2    Farhi, A.3
  • 11
    • 0025076337 scopus 로고
    • Identification and initial characterization of translational initiation factor 2 from bovine mitochondria
    • Liao HX, Spremulli LL: Identification and initial characterization of translational initiation factor 2 from bovine mitochondria. J Biol Chem 1990; 265: 13618-13622.
    • (1990) J Biol Chem , vol.265 , pp. 13618-13622
    • Liao, H.X.1    Spremulli, L.L.2
  • 12
    • 0037144517 scopus 로고    scopus 로고
    • Identification of mammalian mitochondrial translational initiation factor 3 and examination of its role in initiation complex formation with natural mRNAs
    • Koc EC, Spremulli LL: Identification of mammalian mitochondrial translational initiation factor 3 and examination of its role in initiation complex formation with natural mRNAs. J Biol Chem 2002; 277: 35541-35549.
    • (2002) J Biol Chem , vol.277 , pp. 35541-35549
    • Koc, E.C.1    Spremulli, L.L.2
  • 13
    • 33847019962 scopus 로고    scopus 로고
    • Mitochondrial translation initiation factor 3 gene polymorphism associated with Parkinson's disease
    • Abahuni N, Gispert S, Bauer P et al: Mitochondrial translation initiation factor 3 gene polymorphism associated with Parkinson's disease. Neurosci Lett 2007; 414: 126-129.
    • (2007) Neurosci Lett , vol.414 , pp. 126-129
    • Abahuni, N.1    Gispert, S.2    Bauer, P.3
  • 14
    • 34548052424 scopus 로고    scopus 로고
    • Translation matters: Protein synthesis defects in inherited disease
    • Scheper GC, vanPder Knaap MS, Proud CG: Translation matters: protein synthesis defects in inherited disease. Nat Rev Genet 2007; 8 711-723.
    • (2007) Nat Rev Genet , vol.8 , pp. 711-723
    • Scheper, G.C.1    vanPder Knaap, M.S.2    Proud, C.G.3
  • 15
    • 0141538036 scopus 로고    scopus 로고
    • Identification and characterization of mouse MTO1 gene related to mitochondrial tRNA modification
    • Li R, Li X, Yan Q, Qin MJ, Guan MX: Identification and characterization of mouse MTO1 gene related to mitochondrial tRNA modification. Biochim Biophys Acta 2003; 1629 (1-3): 53-59.
    • (2003) Biochim Biophys Acta , vol.1629 , Issue.1-3 , pp. 53-59
    • Li, R.1    Li, X.2    Yan, Q.3    Qin, M.J.4    Guan, M.X.5
  • 16
    • 12544259245 scopus 로고    scopus 로고
    • Mitochondria-specific RNA-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial tRNAs. Implications for the molecular pathogenesis of human mitochondrial diseases
    • Umeda N, Suzuki T, Yukawa M et al: Mitochondria-specific RNA-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial tRNAs. Implications for the molecular pathogenesis of human mitochondrial diseases. J Biol Chem 2005; 280: 1613-1624.
    • (2005) J Biol Chem , vol.280 , pp. 1613-1624
    • Umeda, N.1    Suzuki, T.2    Yukawa, M.3
  • 17
    • 0036837683 scopus 로고    scopus 로고
    • A human mitochondrial GTP binding protein related to tRNA modification may modulate phenotypic expression of the deafness-associated mitochondrial 12S rRNA mutation
    • Li X, Guan MX: A human mitochondrial GTP binding protein related to tRNA modification may modulate phenotypic expression of the deafness-associated mitochondrial 12S rRNA mutation. Mol Cell Biol 2002; 22: 7701-7711.
    • (2002) Mol Cell Biol , vol.22 , pp. 7701-7711
    • Li, X.1    Guan, M.X.2
  • 18
    • 0035344913 scopus 로고    scopus 로고
    • Peripheral blood mitochondrial DNA content is related to insulin sensitivity in offspring of type 2 diabetic patients
    • Song J, Oh JY, Sung YA, Pak YK, Park KS, Lee HK: Peripheral blood mitochondrial DNA content is related to insulin sensitivity in offspring of type 2 diabetic patients. Diabetes Care 2001; 24: 865-869.
    • (2001) Diabetes Care , vol.24 , pp. 865-869
    • Song, J.1    Oh, J.Y.2    Sung, Y.A.3    Pak, Y.K.4    Park, K.S.5    Lee, H.K.6
  • 19
    • 34347353306 scopus 로고    scopus 로고
    • Reduced peripheral blood mitochondrial DNA content is not a risk factor for Type 2 diabetes
    • Singh R, Hattersley AT, Harries LW: Reduced peripheral blood mitochondrial DNA content is not a risk factor for Type 2 diabetes. Diabet Med 2007; 24: 784-787.
    • (2007) Diabet Med , vol.24 , pp. 784-787
    • Singh, R.1    Hattersley, A.T.2    Harries, L.W.3
  • 20
    • 0025829045 scopus 로고
    • Similarity of human mitochondrial transcription factor 1 to high mobility group proteins
    • Parisi MA, Clayton DA: Similarity of human mitochondrial transcription factor 1 to high mobility group proteins. Science 1991; 252: 965-969.
    • (1991) Science , vol.252 , pp. 965-969
    • Parisi, M.A.1    Clayton, D.A.2
  • 21
    • 2442431673 scopus 로고    scopus 로고
    • Mitochondrial transcription factor A regulates mtDNA copy number in mammals
    • Ekstrand MI, Falkenberg M, Rantanen A et al: Mitochondrial transcription factor A regulates mtDNA copy number in mammals. Hum Mol Genet 2004; 13: 935-944.
    • (2004) Hum Mol Genet , vol.13 , pp. 935-944
    • Ekstrand, M.I.1    Falkenberg, M.2    Rantanen, A.3
  • 22
    • 0035016566 scopus 로고    scopus 로고
    • Pgc-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells
    • Andersson U, Scarpulla RC: Pgc-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells. Mol Cell Biol 2001; 21: 3738-3749.
    • (2001) Mol Cell Biol , vol.21 , pp. 3738-3749
    • Andersson, U.1    Scarpulla, R.C.2
  • 23
    • 17144424946 scopus 로고    scopus 로고
    • SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes
    • Shi T, Wang F, Stieren E, Tong Q: SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes. J Biol Chem 2005; 280: 13560-13567.
    • (2005) J Biol Chem , vol.280 , pp. 13560-13567
    • Shi, T.1    Wang, F.2    Stieren, E.3    Tong, Q.4
  • 24
    • 33748199578 scopus 로고    scopus 로고
    • Insulin secretion: SIRT4 gets in on the act
    • Argmann C, Auwerx J: Insulin secretion: SIRT4 gets in on the act. Cell 2006; 126: 837-839.
    • (2006) Cell , vol.126 , pp. 837-839
    • Argmann, C.1    Auwerx, J.2
  • 26
    • 0018846846 scopus 로고
    • Enzymes of glycerolipid synthesis in eukaryotes
    • Bell RM, Coleman RA: Enzymes of glycerolipid synthesis in eukaryotes. Annu Rev Biochem 1980; 49: 459-487.
    • (1980) Annu Rev Biochem , vol.49 , pp. 459-487
    • Bell, R.M.1    Coleman, R.A.2
  • 27
    • 21844451391 scopus 로고    scopus 로고
    • Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential in liver for the metabolism of excess acyl-CoAs
    • Hammond LE, Neschen S, Romanelli AJ et al: Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential in liver for the metabolism of excess acyl-CoAs. J Biol Chem 2005; 280: 25629-25636.
    • (2005) J Biol Chem , vol.280 , pp. 25629-25636
    • Hammond, L.E.1    Neschen, S.2    Romanelli, A.J.3
  • 28
    • 79959524146 scopus 로고    scopus 로고
    • A haplotype map of the human genome
    • The International HapMap Consortium
    • The International HapMap Consortium: A haplotype map of the human genome. Nature 2005; 437: 1299-1320.
    • (2005) Nature , vol.437 , pp. 1299-1320
  • 30
    • 0029149309 scopus 로고
    • Prevalence and determinants of glucose intolerance in a Dutch caucasian population. The Hoorn Study
    • Mooy JM, Grootenhuis PA, de VH et al: Prevalence and determinants of glucose intolerance in a Dutch caucasian population. The Hoorn Study. Diabetes Care 1995; 18: 1270-1273.
    • (1995) Diabetes Care , vol.18 , pp. 1270-1273
    • Mooy, J.M.1    Grootenhuis2    PA, D.V.3
  • 32
    • 67749116741 scopus 로고    scopus 로고
    • Limited agreement between HbA1c and glucose in the general Dutch population: The New Hoorn Study
    • abstract
    • van 't Riet E, Rijkelijkhuizen JM, Nijpels G, Dekker JM: Limited agreement between HbA1c and glucose in the general Dutch population: The New Hoorn Study. Diabetologia 2008; 51 (Suppl 1): S164, (abstract).
    • (2008) Diabetologia , vol.51 , Issue.SUPPL. 1
    • van 't Riet, E.1    Rijkelijkhuizen, J.M.2    Nijpels, G.3    Dekker, J.M.4
  • 33
    • 0037692891 scopus 로고    scopus 로고
    • A genome-wide scan in type 2 diabetes mellitus provides independent replication of a susceptibility locus on 18p11 and suggests the existence of novel Loci on 2q12 and 19q13
    • van Tilburg JH, Sandkuijl LA, Strengman E et al: A genome-wide scan in type 2 diabetes mellitus provides independent replication of a susceptibility locus on 18p11 and suggests the existence of novel Loci on 2q12 and 19q13. J Clin Endocrinol Metab 2003; 88: 2223-2230.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2223-2230
    • van Tilburg, J.H.1    Sandkuijl, L.A.2    Strengman, E.3
  • 34
    • 28444452580 scopus 로고    scopus 로고
    • Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect
    • Monsuur AJ, de Bakker PI, Alizadeh BZ et al: Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect. Nat Genet 2005; 37: 1341-1344.
    • (2005) Nat Genet , vol.37 , pp. 1341-1344
    • Monsuur, A.J.1    de Bakker, P.I.2    Alizadeh, B.Z.3
  • 35
    • 0025767240 scopus 로고
    • Determinants of disease and disability in the elderly: The Rotterdam Elderly Study
    • Hofman A, Grobbee DE, de Jong PT, van den Ouweland FA: Determinants of disease and disability in the elderly: The Rotterdam Elderly Study. Eur J Epidemiol 1991; 7: 403-422.
    • (1991) Eur J Epidemiol , vol.7 , pp. 403-422
    • Hofman, A.1    Grobbee, D.E.2    de Jong, P.T.3    van den Ouweland, F.A.4
  • 36
    • 0035085146 scopus 로고    scopus 로고
    • Increasing prevalence of diabetes mellitus and impaired glucose tolerance among 60-year-old Danes
    • Drivsholm T, Ibsen H, Schroll M, Davidsen M, Borch-Johnsen K: Increasing prevalence of diabetes mellitus and impaired glucose tolerance among 60-year-old Danes. Diabet Med 2001; 18: 126-132.
    • (2001) Diabet Med , vol.18 , pp. 126-132
    • Drivsholm, T.1    Ibsen, H.2    Schroll, M.3    Davidsen, M.4    Borch-Johnsen, K.5
  • 37
    • 0036499241 scopus 로고    scopus 로고
    • Sample size requirements for association studies of gene-gene interaction
    • Gauderman WJ: Sample size requirements for association studies of gene-gene interaction. Am J Epidemiol 2002; 155: 478-484.
    • (2002) Am J Epidemiol , vol.155 , pp. 478-484
    • Gauderman, W.J.1
  • 38
    • 34249888775 scopus 로고    scopus 로고
    • Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
    • The Diabetes Genetics Initiative of the Broad Institute of MIT and Harvard, Lund University and Novartis Institutes for BioMedical Research
    • The Diabetes Genetics Initiative of the Broad Institute of MIT and Harvard, Lund University and Novartis Institutes for BioMedical Research. et al: Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 2007; 316 1331-1336.
    • (2007) Science , vol.316 , pp. 1331-1336
  • 39
    • 34249895023 scopus 로고    scopus 로고
    • Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes
    • Zeggini E, Weedon MN, Lindgren CM et al: Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science 2007; 316: 1336-1341.
    • (2007) Science , vol.316 , pp. 1336-1341
    • Zeggini, E.1    Weedon, M.N.2    Lindgren, C.M.3
  • 40
    • 42349106044 scopus 로고    scopus 로고
    • Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
    • Zeggini E, Scott LJ, Saxena R et al: Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet 2008; 40: 638-645.
    • (2008) Nat Genet , vol.40 , pp. 638-645
    • Zeggini, E.1    Scott, L.J.2    Saxena, R.3
  • 41
    • 42349112088 scopus 로고    scopus 로고
    • Genome-wide association studies for complex traits: Consensus, uncertainty and challenges
    • McCarthy MI, Abecasis GR, Cardon LR et al: Genome-wide association studies for complex traits: Consensus, uncertainty and challenges. Nat Rev Genet 2008; 9: 356-369.
    • (2008) Nat Rev Genet , vol.9 , pp. 356-369
    • McCarthy, M.I.1    Abecasis, G.R.2    Cardon, L.R.3
  • 42
    • 33847176604 scopus 로고    scopus 로고
    • A genome-wide association study identifies novel risk loci for type 2 diabetes
    • Sladek R, Rocheleau G, Rung J et al: A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature 2007; 445: 881-885.
    • (2007) Nature , vol.445 , pp. 881-885
    • Sladek, R.1    Rocheleau, G.2    Rung, J.3
  • 43
    • 34249885875 scopus 로고    scopus 로고
    • A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants
    • Scott LJ, Mohlke KL, Bonnycastle LL et al: A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 2007; 316: 1341-1345.
    • (2007) Science , vol.316 , pp. 1341-1345
    • Scott, L.J.1    Mohlke, K.L.2    Bonnycastle, L.L.3
  • 44
    • 0035676129 scopus 로고    scopus 로고
    • Mutation analysis of peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1) and relationships of identified amino acid polymorphisms to Type II diabetes mellitus
    • Ek J, Andersen G, Urhammer SA et al: Mutation analysis of peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1) and relationships of identified amino acid polymorphisms to Type II diabetes mellitus. Diabetologia 2001; 44: 2220-2226.
    • (2001) Diabetologia , vol.44 , pp. 2220-2226
    • Ek, J.1    Andersen, G.2    Urhammer, S.A.3
  • 45
    • 0036830548 scopus 로고    scopus 로고
    • A functional polymorphism in the promoter of UCP2 enhances obesity risk but reduces type 2 diabetes risk in obese middle-aged humans
    • Krempler F, Esterbauer H, Weitgasser R et al: A functional polymorphism in the promoter of UCP2 enhances obesity risk but reduces type 2 diabetes risk in obese middle-aged humans. Diabetes 2002; 51: 3331-3335.
    • (2002) Diabetes , vol.51 , pp. 3331-3335
    • Krempler, F.1    Esterbauer, H.2    Weitgasser, R.3
  • 46
    • 33244465167 scopus 로고    scopus 로고
    • Meta-analysis of the Gly482Ser variant in PPARGC1A in type 2 diabetes and related phenotypes
    • Barroso I, Luan J, Sandhu MS et al: Meta-analysis of the Gly482Ser variant in PPARGC1A in type 2 diabetes and related phenotypes. Diabetologia 2006; 49: 501-505.
    • (2006) Diabetologia , vol.49 , pp. 501-505
    • Barroso, I.1    Luan, J.2    Sandhu, M.S.3
  • 47
    • 33745312588 scopus 로고    scopus 로고
    • Variation in the UCP2-UCP3 gene cluster predicts the development of type 2 diabetes in healthy middle-aged men
    • Gable DR, Stephens JW, Cooper JA, Miller GJ, Humphries SE: Variation in the UCP2-UCP3 gene cluster predicts the development of type 2 diabetes in healthy middle-aged men. Diabetes 2006; 55: 1504-1511.
    • (2006) Diabetes , vol.55 , pp. 1504-1511
    • Gable, D.R.1    Stephens, J.W.2    Cooper, J.A.3    Miller, G.J.4    Humphries, S.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.