Apical membrane localization of the adenomatous polyposis coli tumor suppressor protein and subcellular distribution of the β-catenin destruction complex in polarized epithelial cells

Journal of Cell Biology

Volumn 153, Issue 3, 2001, Pages 491-502

  Reinacher Schick, Anke ^a   Gumbiner, Barry M ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Adenomatous polyposis coli; Destruction complex; Epithelial cells; Fractionation; Localization

Indexed keywords

APC PROTEIN; AXIN; BETA CATENIN; GLYCOGEN SYNTHASE; PROTEIN KINASE; AXIN PROTEIN; CATNB PROTEIN, MOUSE; CTNNB1 PROTEIN, HUMAN; CYTOSKELETON PROTEIN; DISHEVELLED PROTEINS; GLYCOGEN SYNTHASE KINASE; GLYCOGEN SYNTHASE KINASE 3; PHOSPHOPROTEIN; PROTEIN; PROTEIN KINASE (CALCIUM,CALMODULIN); REPRESSOR PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TRANSACTIVATOR PROTEIN; TUMOR PROTEIN;

APICAL MEMBRANE; ARTICLE; CANCER RISK; CELL FRACTIONATION; CELL TYPE; CELLULAR DISTRIBUTION; COLON CANCER; COLON CARCINOGENESIS; COLON POLYPOSIS; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; TUMOR SUPPRESSOR GENE; ANIMAL; BREAST TUMOR; CARCINOMA; CELL CULTURE; CELL MEMBRANE; CELL POLARITY; COLON; COLON TUMOR; CYTOLOGY; EPITHELIUM CELL; FEMALE; FLUORESCENCE MICROSCOPY; METABOLISM; MOUSE; PATHOLOGY; PROTEIN TERTIARY STRUCTURE; WESTERN BLOTTING;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOMATOUS POLYPOSIS COLI PROTEIN; ANIMALS; BETA CATENIN; BLOTTING, WESTERN; BREAST NEOPLASMS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CARCINOMA; CELL FRACTIONATION; CELL MEMBRANE; CELL POLARITY; COLON; COLONIC NEOPLASMS; CYTOSKELETAL PROTEINS; EPITHELIAL CELLS; FEMALE; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASES; HUMANS; MICE; MICROSCOPY, FLUORESCENCE; NEOPLASM PROTEINS; PHOSPHOPROTEINS; PROTEIN STRUCTURE, TERTIARY; PROTEINS; REPRESSOR PROTEINS; TRANS-ACTIVATORS; TUMOR CELLS, CULTURED;

EID: 0035809193     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.153.3.491     Document Type: Article

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