메뉴 건너뛰기




Volumn 30, Issue 8, 2009, Pages 1207-1213

APP and BACE1 miRNA genetic variability has no major role in risk for Alzheimer disease

Author keywords

Alzheimer; APP; Association; BACE1; miRNA

Indexed keywords

AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; MICRORNA;

EID: 67749094957     PISSN: 10597794     EISSN: None     Source Type: Journal    
DOI: 10.1002/humu.21027     Document Type: Article
Times cited : (49)

References (40)
  • 1
    • 26844498125 scopus 로고    scopus 로고
    • Abelson JF, Kwan KY, O'Roak BJ, Baek DY, Stillman AA, Morgan TM, Mathews CA, Pauls DL, Rasin MR, Gunel M, Davis NR, Ercan-Sencicek AG, Guez DH, Spertus JA, Leckman JF, Dure LS, Kurlan R, Singer HS, Gilbert DL, Farhi A, Louvi A, Lifton RP, Sestan N, State MW. 2005. Sequence variants in SLITRK1 are associated with Tourette's syndrome. Science 310:317-320.
    • Abelson JF, Kwan KY, O'Roak BJ, Baek DY, Stillman AA, Morgan TM, Mathews CA, Pauls DL, Rasin MR, Gunel M, Davis NR, Ercan-Sencicek AG, Guez DH, Spertus JA, Leckman JF, Dure LS, Kurlan R, Singer HS, Gilbert DL, Farhi A, Louvi A, Lifton RP, Sestan N, State MW. 2005. Sequence variants in SLITRK1 are associated with Tourette's syndrome. Science 310:317-320.
  • 6
    • 0035798269 scopus 로고    scopus 로고
    • Cruts M, Dermaut B, Rademakers R, Roks G, Van den Broeck M, Munteanu G, van Duijn CM, Van Broeckhoven C. 2001. Amyloid beta secretase gene (BACE) is neither mutated in nor associated with early-onset Alzheimer's disease. Neurosci Lett 313:105-107.
    • Cruts M, Dermaut B, Rademakers R, Roks G, Van den Broeck M, Munteanu G, van Duijn CM, Van Broeckhoven C. 2001. Amyloid beta secretase gene (BACE) is neither mutated in nor associated with early-onset Alzheimer's disease. Neurosci Lett 313:105-107.
  • 7
    • 9244263071 scopus 로고    scopus 로고
    • BACE1 and presenilin: Two unusual aspartyl proteases involved in Alzheimer's disease
    • Dominguez DI, Hartmann D, De Strooper B. 2004. BACE1 and presenilin: two unusual aspartyl proteases involved in Alzheimer's disease. Neurodegener Dis 1:168-174.
    • (2004) Neurodegener Dis , vol.1 , pp. 168-174
    • Dominguez, D.I.1    Hartmann, D.2    De Strooper, B.3
  • 8
    • 34447319406 scopus 로고    scopus 로고
    • Single nucleotide polymorphism associated with mature miR-125a alters the processing of pri-miRNA
    • Duan R, Pak C, Jin P. 2007. Single nucleotide polymorphism associated with mature miR-125a alters the processing of pri-miRNA. Hum Mol Genet 16:1124-1131.
    • (2007) Hum Mol Genet , vol.16 , pp. 1124-1131
    • Duan, R.1    Pak, C.2    Jin, P.3
  • 9
    • 0035871971 scopus 로고    scopus 로고
    • Elevated vulnerability to oxidative stress-induced cell death and activation of caspase-3 by the Swedish amyloid precursor protein mutation
    • Eckert A, Steiner B, Marques C, Leutz S, Romig H, Haass C, Muller WE. 2001. Elevated vulnerability to oxidative stress-induced cell death and activation of caspase-3 by the Swedish amyloid precursor protein mutation. J Neurosci Res 64:183-192.
    • (2001) J Neurosci Res , vol.64 , pp. 183-192
    • Eckert, A.1    Steiner, B.2    Marques, C.3    Leutz, S.4    Romig, H.5    Haass, C.6    Muller, W.E.7
  • 13
    • 0016823810 scopus 로고
    • Mini-mental state. A practical method for grading the cognitive state of patients for the clinician
    • Folstein MF, Folstein SE, McHugh PR. 1975. "Mini-mental state." A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12:189-198.
    • (1975) J Psychiatr Res , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 14
    • 0036718272 scopus 로고    scopus 로고
    • Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease
    • Fukumoto H, Cheung BS, Hyman BT, Irizarry MC. 2002. Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease. Arch Neurol 59:1381-1389.
    • (2002) Arch Neurol , vol.59 , pp. 1381-1389
    • Fukumoto, H.1    Cheung, B.S.2    Hyman, B.T.3    Irizarry, M.C.4
  • 16
    • 6944244417 scopus 로고    scopus 로고
    • Functional characterization of the 5′ flanking region of the BACE gene: Identification of a 91 bp fragment involved in basal level of BACE promoter expression
    • Ge YW, Maloney B, Sambamurti K, Lahiri DK. 2004. Functional characterization of the 5′ flanking region of the BACE gene: identification of a 91 bp fragment involved in basal level of BACE promoter expression. FASEB J 18:1037-1039.
    • (2004) FASEB J , vol.18 , pp. 1037-1039
    • Ge, Y.W.1    Maloney, B.2    Sambamurti, K.3    Lahiri, D.K.4
  • 17
    • 34249683280 scopus 로고    scopus 로고
    • Polymorphic miRNA-mediated gene regulation: Contribution to phenotypic variation and disease
    • Georges M, Coppieters W, Charlier C. 2007. Polymorphic miRNA-mediated gene regulation: contribution to phenotypic variation and disease. Curr Opin Genet Dev 17:166-176.
    • (2007) Curr Opin Genet Dev , vol.17 , pp. 166-176
    • Georges, M.1    Coppieters, W.2    Charlier, C.3
  • 19
    • 27344456287 scopus 로고    scopus 로고
    • microRNA target predictions across seven Drosophila species and comparison to mammalian targets
    • Grun D, Wang YL, Langenberger D, Gunsalus KC, Rajewsky N. 2005. microRNA target predictions across seven Drosophila species and comparison to mammalian targets. PLoS Comput Biol 1:e13.
    • (2005) PLoS Comput Biol , vol.1
    • Grun, D.1    Wang, Y.L.2    Langenberger, D.3    Gunsalus, K.C.4    Rajewsky, N.5
  • 21
    • 0036260892 scopus 로고    scopus 로고
    • Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease
    • Holsinger RM, McLean CA, Beyreuther K, Masters CL, Evin G. 2002. Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease. Ann Neurol 51:783-786.
    • (2002) Ann Neurol , vol.51 , pp. 783-786
    • Holsinger, R.M.1    McLean, C.A.2    Beyreuther, K.3    Masters, C.L.4    Evin, G.5
  • 22
    • 33846699083 scopus 로고    scopus 로고
    • A hexanucleotide element directs microRNA nuclear import
    • Hwang HW, Wentzel EA, Mendell JT. 2007. A hexanucleotide element directs microRNA nuclear import. Science 315:97-100.
    • (2007) Science , vol.315 , pp. 97-100
    • Hwang, H.W.1    Wentzel, E.A.2    Mendell, J.T.3
  • 24
    • 33646878079 scopus 로고    scopus 로고
    • BACE1 gene promoter is differentially regulated: Detection of a novel promoter region for its cell type-specific regulation
    • Lahiri DK, Maloney B, Ge YW. 2006. BACE1 gene promoter is differentially regulated: detection of a novel promoter region for its cell type-specific regulation. J Mol Neurosci 28:193-210.
    • (2006) J Mol Neurosci , vol.28 , pp. 193-210
    • Lahiri, D.K.1    Maloney, B.2    Ge, Y.W.3
  • 27
    • 34347376692 scopus 로고    scopus 로고
    • Characterization of microRNA expression profiles in normal human tissues
    • Liang Y, Ridzon D, Wong L, Chen C. 2007. Characterization of microRNA expression profiles in normal human tissues. BMC Genomics 8:166.
    • (2007) BMC Genomics , vol.8 , pp. 166
    • Liang, Y.1    Ridzon, D.2    Wong, L.3    Chen, C.4
  • 28
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDAWork Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
    • McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. 1984. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDAWork Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34:939-944.
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, E.M.6
  • 31
    • 33747347875 scopus 로고    scopus 로고
    • Transcriptional and translational regulation of BACE1 expression - implications for Alzheimer's disease
    • Rossner S, Sastre M, Bourne K, Lichtenthaler SF. 2006. Transcriptional and translational regulation of BACE1 expression - implications for Alzheimer's disease. Prog Neurobiol 79:95-111.
    • (2006) Prog Neurobiol , vol.79 , pp. 95-111
    • Rossner, S.1    Sastre, M.2    Bourne, K.3    Lichtenthaler, S.F.4
  • 32
    • 29444442794 scopus 로고    scopus 로고
    • Rovelet-Lecrux A, Hannequin D, Raux G, Le Meur N, Laquerrière A, Vital A, Dumanchin C, Feuillette S, Brice A, Vercelletto M, Dubas F, Frebourg T, Campion D. 2006. APP locus duplication causes autosomal dominant earlyonset Alzheimer disease with cerebral amyloid angiopathy. Nat Genet 38:24-26.
    • Rovelet-Lecrux A, Hannequin D, Raux G, Le Meur N, Laquerrière A, Vital A, Dumanchin C, Feuillette S, Brice A, Vercelletto M, Dubas F, Frebourg T, Campion D. 2006. APP locus duplication causes autosomal dominant earlyonset Alzheimer disease with cerebral amyloid angiopathy. Nat Genet 38:24-26.
  • 33
    • 0033990048 scopus 로고    scopus 로고
    • Primer3 on the WWW for general users and for biologist programmers
    • Rozen S, Skaletsky H. 2000. Primer3 on the WWW for general users and for biologist programmers. Methods Mol Biol 132:365-386.
    • (2000) Methods Mol Biol , vol.132 , pp. 365-386
    • Rozen, S.1    Skaletsky, H.2
  • 34
    • 6944231363 scopus 로고    scopus 로고
    • Gene structure and organization of the human beta-secretase (BACE) promoter
    • Sambamurti K, Kinsey R, Maloney B, Ge YW, Lahiri DK. 2004. Gene structure and organization of the human beta-secretase (BACE) promoter. FASEB J 18:1034-1036.
    • (2004) FASEB J , vol.18 , pp. 1034-1036
    • Sambamurti, K.1    Kinsey, R.2    Maloney, B.3    Ge, Y.W.4    Lahiri, D.K.5
  • 37
    • 33750579333 scopus 로고    scopus 로고
    • Sleegers K, Brouwers N, Gijselinck I, Theuns J, Goossens D, Wauters J, Del Favero J, Cruts M, van Duijn CM, Van Broeckhoven C. 2006. APP duplication is sufficient to cause early onset Alzheimer's dementia with cerebral amyloid angiopathy. Brain 129:2977-2983.
    • Sleegers K, Brouwers N, Gijselinck I, Theuns J, Goossens D, Wauters J, Del Favero J, Cruts M, van Duijn CM, Van Broeckhoven C. 2006. APP duplication is sufficient to cause early onset Alzheimer's dementia with cerebral amyloid angiopathy. Brain 129:2977-2983.
  • 40
    • 38749095507 scopus 로고    scopus 로고
    • The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1
    • Wang WX, Rajeev BW, Stromberg AJ, Ren N, Tang G, Huang Q, Rigoutsos I, Nelson PT. 2008. The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1. J Neurosci 28:1213-1223.
    • (2008) J Neurosci , vol.28 , pp. 1213-1223
    • Wang, W.X.1    Rajeev, B.W.2    Stromberg, A.J.3    Ren, N.4    Tang, G.5    Huang, Q.6    Rigoutsos, I.7    Nelson, P.T.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.