Supplemental calcium attenuates the colitis-related increase in diarrhea, intestinal permeability, and extracellular matrix breakdown in HLA-B27 transgenic rats

Journal of Nutrition

Volumn 139, Issue 8, 2009, Pages 1525-1533

  Schepens, Marloes A A ^a,b   Schonewille, Arjan J ^a,b   Vink, Carolien ^a,b   Van Schothorst, Evert M ^a,c   Kramer, Evelien ^a,c   Hendriks, Thijs ^d   Brummer, Robert Jan ^a   Keijer, Jaap ^c   Van Der Meer, Roelof ^a,b   Bovee Oudenhoven, Ingeborg M J ^a,b  

^a TOP INSTITUTE FOOD AND NUTRITION   (Netherlands)

^b NIZO FOOD RESEARCH   (Netherlands)

^c WAGENINGEN UNIVERSITY   (Netherlands)

^d RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; EDETATE CHROMIUM; FIBRONECTIN; HLA B27 ANTIGEN; INTERLEUKIN 1; INTERLEUKIN 1BETA; MATRIX METALLOPROTEINASE; PROCOLLAGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM INTAKE; COL5A2 GENE; COLITIS; COLON MUCOSA; CONTROLLED STUDY; DIARRHEA; DIET SUPPLEMENTATION; DISEASE SEVERITY; ENTERITIS; EXPERIMENTAL MODEL; EXPERIMENTAL RAT; EXTRACELLULAR MATRIX; FECES ANALYSIS; FEMALE; FN1 GENE; GENE; GENE EXPRESSION; GENOME ANALYSIS; HISTOLOGY; INTESTINE MUCOSA PERMEABILITY; LIPID DIET; MICROARRAY ANALYSIS; MMP GENE; NONHUMAN; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; TRANSGENIC RAT; URINARY EXCRETION; WEIGHT; ZYMOGRAPHY;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CALCIUM; CALCIUM, DIETARY; COLITIS; COLON; DIARRHEA; DIETARY SUPPLEMENTS; DISEASE MODELS, ANIMAL; EDETIC ACID; EXTRACELLULAR MATRIX; FECES; FEMALE; FIBRONECTINS; GENE EXPRESSION; HLA-B27 ANTIGEN; INTERLEUKIN-1BETA; INTESTINAL ABSORPTION; MATRIX METALLOPROTEINASES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PERMEABILITY; PROCOLLAGEN; RATS; RATS, TRANSGENIC;

RATTUS;

EID: 67749088132     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.109.105205     Document Type: Article

References (45)

1. Sartor RB. Mechanisms of disease: pathogenesis of Crohn's disease and ulcerative colitis. Nat Clin Pract Gastroenterol Hepatol. 2006;3:390-407.
2. Ling SC, Griffiths AM. Nutrition in inflammatory bowel disease. Curr Opin Clin Nutr Metab Care. 2000;3:339-44.
3. Bovee-Oudenhoven IM, Lettink-Wissink ML, Van Doesburg W, Witteman BJ, Van Der Meer R. Diarrhea caused by enterotoxigenic Escherichia coli infection of humans is inhibited by dietary calcium. Gastroenterology. 2003;125:469-76.
4. Bovee-Oudenhoven IM, Termont DS, Weerkamp AH, Faassen-Peters MA, Van der Meer R. Dietary calcium inhibits the intestinal colonization and translocation of Salmonella in rats. Gastroenterology. 1997;113:550-7.
5. Ten Bruggencate SJ, Bovee-Oudenhoven IM, Lettink-Wissink ML, Katan MB, Van Der Meer R. Dietary fructo-oligosaccharides and inulin decrease resistance of rats to salmonella: protective role of calcium. Gut. 2004;53:530-5.
6. Govers MJ, Termont DS, Lapre JA, Kleibeuker JH, Vonk RJ, Van der Meer R. Calcium in milk products precipitates intestinal fatty acids and secondary bile acids and thus inhibits colonic cytotoxicity in humans. Cancer Res. 1996;56:3270-5.
7. Lapre JA, De Vries HT, Koeman JH, Van der Meer R. The antiproliferative effect of dietary calcium on colonic epithelium is mediated by luminal surfactants and dependent on the type of dietary fat. Cancer Res. 1993;53:784-9.
8. Zhu Y, Mahon BD, Froicu M, Cantorna MT. Calcium and 1 alpha,25-dihydroxyvitamin D3 target the TNF-alpha pathway to suppress experimental inflammatory bowel disease. Eur J Immunol. 2005;35:217-24.
9. Pele LC, Thoree V, Mustafa F, He S, Tsaprouni L, Punchard NA, Thompson RP, Evans SM, Powell JJ. Low dietary calcium levels modulate mucosal caspase expression and increase disease activity in mice with dextran sulfate sodium induced colitis. J Nutr. 2007;137:2475-80.
10. Sartor RB. Colitis in HLA-B27/beta 2 microglobulin transgenic rats. Int Rev Immunol. 2000;19:39-50.
11. Qian BF, Tonkonogy SL, Sartor RB. Aberrant innate immune responses in TLR-ligand activated HLA-B27 transgenic rat cells. Inflamm Bowel Dis. 2008;14:1358-65.
12. Arslan G, Atasever T, Cindoruk M, Yildirim IS. (51)CrEDTA colonic permeability and therapy response in patients with ulcerative colitis. Nucl Med Commun. 2001;22:997-1001.
13. Binnerts W, Van het Klooster A, Frens A. Soluble chromium indicator measured by atomic absorption in digestion experiments. Vet Rec. 1968;82:470.
14. Sesink AL, Termont DS, Kleibeuker JH, Van der Meer R. Red meat and colon cancer: the cytotoxic and hyperproliferative effects of dietary heme. Cancer Res. 1999;59:5704-9.
15. Bovee-Oudenhoven I, Termont D, Dekker R, Van der Meer R. Calcium in milk and fermentation by yoghurt bacteria increase the resistance of rats to Salmonella infection. Gut. 1996;38:59-65.
16. Lapre JA, Termont DS, Groen AK, Van der Meer R. Lytic effects of mixed micelles of fatty acids and bile acids. Am J Physiol. 1992;263:G333-7.
17. Rath HC, Herfarth HH, Ikeda JS, Grenther WB, Hamm TE Jr, Balish E, Taurog JD, Hammer RE, Wilson KH, et al. Normal luminal bacteria, especially Bacteroides species, mediate chronic colitis, gastritis, and arthritis in HLA-B27/human beta2 microglobulin transgenic rats. J Clin Invest. 1996;98:945-53.
18. Dieleman LA, Goerres MS, Arends A, Sprengers D, Torrice C, Hoentjen F, Grenther WB, Sartor RB. Lactobacillus GG prevents recurrence of colitis in HLA-B27 transgenic rats after antibiotic treatment. Gut. 2003;52:370-6.
19. Wettenhall JM, Smyth GK. limmaGUI: a graphical user interface for linear modeling of microarray data. Bioinformatics. 2004;20:3705-6.
20. Pellis L, Franssen-van Hal NL, Burema J, Keijer J. The intraclass correlation coefficient applied for evaluation of data correction, labeling methods, and rectal biopsy sampling in DNA microarray experiments. Physiol Genomics. 2003;16:99-106.
21. Lee HK, Braynen W, Keshav K, Pavlidis P. ErmineJ: tool for functional analysis of gene expression data sets. BMC Bioinformatics. 2005;6:269.
22. Rodenburg W, Keijer J, Kramer E, Roosing S, Vink C, Katan MB, van der Meer R, Bovee-Oudenhoven IM. Salmonella induces prominent gene expression in the rat colon. BMC Microbiol. 2007;7:84.
23. Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, De Paepe A, Speleman F. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol. 2002;3:RESEARCH0034.
24. de Hingh IH, Lomme RM, van Goor H, Bleichrodt RP, Hendriks T. Changes in gelatinase activity in the gastrointestinal tract after anastomotic construction in the ileum or colon. Dis Colon Rectum. 2005;48:2133-41.
25. Medina C, Santana A, Paz MC, Diaz F, Farre E, Salas A, Radomski MW, Quintero E. Matrix metalloproteinase-9 modulates intestinal injury in rats with transmural colitis. J Leukoc Biol.2006;79:954-62.
26. Castaneda FE, Walia B, Vijay-Kumar M, Patel NR, Roser S, Kolachala VL, Rojas M, Wang L, Oprea G, et al. Targeted deletion of metalloproteinase 9 attenuates experimental colitis in mice: central role of epithelial-derived MMP. Gastroenterology. 2005;129:1991-2008.
27. Santana A, Medina C, Paz-Cabrera MC, Diaz-Gonzalez F, Farre E, Salas A, Radomski MW, Quintero E. Attenuation of dextran sodium sulphate induced colitis in matrix metalloproteinase-9 deficient mice. World J Gastroenterol. 2006;12:6464-72.
28. Arrieta MC, Bistritz L, Meddings JB. Alterations in intestinal permeability. Gut. 2006;55:1512-20.
29. Arnott ID, Kingstone K, Ghosh S. Abnormal intestinal permeability predicts relapse in inactive Crohn disease. Scand J Gastroenterol. 2000;35:1163-9.
30. Wyatt J, Vogelsang H, Hubl W, Waldhoer T, Lochs H. Intestinal permeability and the prediction of relapse in Crohn's disease. Lancet. 1993;341:1437-9.
31. Govers MJ, Van der Meer R. Effects of dietary calcium and phosphate on the intestinal interactions between calcium, phosphate, fatty acids, and bile acids. Gut. 1993;34:365-70.
32. Van der Meer R, Welberg JW, Kuipers F, Kleibeuker JH, Mulder NH, Termont DS, Vonk RJ, De Vries HT, De Vries EG. Effects of supplemental dietary calcium on the intestinal association of calcium, phosphate, and bile acids. Gastroenterology. 1990;99:1653-9.
33. Afman L, Muller M. Nutrigenomics: from molecular nutrition to prevention of disease. J Am Diet Assoc. 2006;106:569-76.
34. Rodenburg W, Heidema AG, Boer JM, Bovee-Oudenhoven IM, Feskens EJ, Mariman EC, Keijer J. A framework to identify physiological responses in microarray-based gene expression studies: selection and interpretation of biologically relevant genes. Physiol Genomics. 2008;33:78-90.
35. Medina C, Radomski MW. Role of matrix metalloproteinases in intestinal inflammation. J Pharmacol Exp Ther. 2006;318:933-8.
36. Baugh MD, Perry MJ, Hollander AP, Davies DR, Cross SS, Lobo AJ, Taylor CJ, Evans GS. Matrix metalloproteinase levels are elevated in inflammatory bowel disease. Gastroenterology. 1999;117:814-22.
37. von Lampe B, Barthel B, Coupland SE, Riecken EO, Rosewicz S. Differential expression of matrix metalloproteinases and their tissue inhibitors in colon mucosa of patients with inflammatory bowel disease. Gut. 2000;47:63-73.
38. Graham MF, Diegelmann RF, Elson CO, Lindblad WJ, Gotschalk N, Gay S, Gay R. Collagen content and types in the intestinal strictures of Crohn's disease. Gastroenterology. 1988;94:257-65.
39. Kodicek E. The absorption of calcium from the intestine. Proc Nutr Soc. 1967;26:67-72.
40. Appleton GV, Owen RW, Wheeler EE, Challacombe DN, Williamson RC. Effect of dietary calcium on the colonic luminal environment. Gut. 1991;32:1374-7.
41. Bruewer M, Samarin S, Nusrat A. Inflammatory bowel disease and the apical junctional complex. Ann N Y Acad Sci. 2006;1072:242-52.
42. Gonzalez-Mariscal L, Contreras RG, Bolivar JJ, Ponce A, Chavez De Ramirez B, Cereijido M. Role of calcium in tight junction formation between epithelial cells. Am J Physiol. 1990;259:C978-86.
43. Crowther RS, Marriott C, James SL. Cation induced changes in the rheological properties of purified mucus glycoprotein gels. Biorheology. 1984;21:253-63.
44. Reeves PG, Nielsen FH, Fahey GC Jr. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr. 1993;123:1939-51.
45. Alaimo K, McDowell MA, Briefel RR, Bischof AM, Caughman CR, Loria CM, Johnson CL. Dietary intake of vitamins, minerals, and fiber of persons ages 2 months and over in the United States: Third National Health and Nutrition Examination Survey, Phase 1, 1988-91. Adv Data. 1994;258:1-28.