Structural basis for m7G-cap hypermethylation of small nuclear, small nucleolar and telomerase RNA by the dimethyltransferase TGS1

Nucleic Acids Research

Volumn 37, Issue 12, 2009, Pages 3865-3877

  Monecke, Thomas ^a   Dickmanns, Achim ^a   Ficner, Ralf ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

7 METHYLGUANOSINE; 7 METHYLGUANOSINE TRIPHOSPHATE; CAP BINDING PROTEIN; GUANOSINE TRIPHOSPHATE; METHYLTRANSFERASE; PEPTIDE SYNTHASE; RNA; S ADENOSYLHOMOCYSTEINE; SMALL NUCLEAR RNA; SMALL NUCLEOLAR RNA; TELOMERASE RNA; TRIMETHYLGUANOSINE SYNTHASE 1; UNCLASSIFIED DRUG; 7-METHYLGUANOSINE TRIPHOSPHATE; CAPPED RNA; TELOMERASE; TRIMETHYLGUANOSINE SYNTHASE;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME STRUCTURE; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; HUMAN; HYPERMETHYLATION; METHYLATION; MOLECULAR RECOGNITION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN RNA BINDING; STRUCTURE ACTIVITY RELATION; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; METABOLISM; SITE DIRECTED MUTAGENESIS; X RAY CRYSTALLOGRAPHY;

MAMMALIA;

BINDING SITES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; HUMANS; METHYLATION; METHYLTRANSFERASES; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; RNA; RNA CAP ANALOGS; RNA, SMALL NUCLEAR; RNA, SMALL NUCLEOLAR; S-ADENOSYLHOMOCYSTEINE; TELOMERASE;

EID: 67651159060     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkp249     Document Type: Article

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