Novel 2,4,5-trisubstituted oxazole derivatives: Synthesis and antiproliferative activity

European Journal of Medicinal Chemistry

Volumn 44, Issue 10, 2009, Pages 3930-3935

  Liu, Xin Hua ^a,b   Lv, Peng Cheng ^a   Xue, Jia Yu ^a   Song, Bao An ^c   Zhu, Hai Liang ^a,b  

^a NANJING UNIVERSITY   (China)

^b ANHUI UNIVERSITY OF TECHNOLOGY   (China)

^c GUIZHOU UNIVERSITY   (China)

Author keywords

Antiproliferative activity; Oxazole; Structure activity relationship; Synthesis

Indexed keywords

2 [2 (2 FLUOROPHENYL) 4 (2,3,4 TRIMETHOXYPHENYL)OXAZOL 5 YLTHIO] 5 METHYL 1,3,4 THIADIAZOLE; 2 [2 (2 FLUOROPHENYL) 4 (2,3,4 TRIMETHOXYPHENYL)OXAZOL 5 YLTHIO]BENZO[D]THIAZOLE; 2 [2 (PYRIDIN 3 YL) 4 (2,3,4 TRIMETHOXYPHENYL)OXAZOL 5 YLTHIO]PYRIMIDINE; FLUOROURACIL; OXAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; MICROWAVE IRRADIATION; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS;

CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; INHIBITORY CONCENTRATION 50; MALE; OXAZOLES; PROSTATIC NEOPLASMS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 67651147984     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.04.019     Document Type: Article

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