-
1
-
-
27644510382
-
Maraviroc (UK-427,857), a potent, orally bioavailable, and selective small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum antihuman immunodeficiency virus type 1 activity
-
Dorr P, Westby M, Dobbs S, Griffin P, Irvine B, Macartney M, et al. Maraviroc (UK-427,857), a potent, orally bioavailable, and selective small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum antihuman immunodeficiency virus type 1 activity. Antimicrob Agents Chemother 2005; 49:4721-4732.
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 4721-4732
-
-
Dorr, P.1
Westby, M.2
Dobbs, S.3
Griffin, P.4
Irvine, B.5
Macartney, M.6
-
2
-
-
54849146700
-
Maraviroc for previously treated patients with R5 HIV-1 infection
-
Gulick RM, Lalezari J, Goodrich J, Clumeck N, DeJesus E, Horban A, et al. Maraviroc for previously treated patients with R5 HIV-1 infection. N Engl J Med 2008;359:1429-1441.
-
(2008)
N Engl J Med
, vol.359
, pp. 1429-1441
-
-
Gulick, R.M.1
Lalezari, J.2
Goodrich, J.3
Clumeck, N.4
DeJesus, E.5
Horban, A.6
-
3
-
-
33646443202
-
Emergence of CXCR4-using human immunodeficiency virus type 1 (HIV-1) variants in a minority of HIV-1-infected patients following treatment with the CCR5 antagonist mar- aviroc is from a pretreatment CXCR4-using virus reservoir
-
Westby M, Lewis M, Whitcomb J, Youle M, Pozniak AL, James IT, et al. Emergence of CXCR4-using human immunodeficiency virus type 1 (HIV-1) variants in a minority of HIV-1-infected patients following treatment with the CCR5 antagonist mar- aviroc is from a pretreatment CXCR4-using virus reservoir. J Virol 2006;80:4909-4920.
-
(2006)
J Virol
, vol.80
, pp. 4909-4920
-
-
Westby, M.1
Lewis, M.2
Whitcomb, J.3
Youle, M.4
Pozniak, A.L.5
James, I.T.6
-
4
-
-
33846623260
-
Development and characterization of a novel single-cycle recombinant-virus assay to determine human immunodeficiency virus type 1 coreceptor tropism
-
Whitcomb JM, Huang W, Fransen S, Limoli K, Toma J, Wrin T, et al. Development and characterization of a novel single-cycle recombinant-virus assay to determine human immunodeficiency virus type 1 coreceptor tropism. Antimicrob Agents Chemother 2007;51:566-575.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 566-575
-
-
Whitcomb, J.M.1
Huang, W.2
Fransen, S.3
Limoli, K.4
Toma, J.5
Wrin, T.6
-
5
-
-
0025783669
-
Identification of the envelope V3 loop as the primary determinant of cell tropism in HIV-1
-
Hwang SS, Boyle TJ, Lyerly HK, Cullen BR. Identification of the envelope V3 loop as the primary determinant of cell tropism in HIV-1. Science 1991;253:71-74.
-
(1991)
Science
, vol.253
, pp. 71-74
-
-
Hwang, S.S.1
Boyle, T.J.2
Lyerly, H.K.3
Cullen, B.R.4
-
6
-
-
0026754683
-
Small amino acid changes in the V3 hypervariable region of gp120 can affect the T-cell-line and macrophage tropism of human immunodeficiency virus type 1
-
ShiodaT, LevyJA, Cheng-MayerC. Small amino acid changes in the V3 hypervariable region of gp120 can affect the T-cell-line and macrophage tropism of human immunodeficiency virus type 1. Proc Natl Acad Sci USA 1992; 89:9434-9438.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 9434-9438
-
-
ShiodaT1
LevyJA2
Cheng-MayerC3
-
7
-
-
12144287132
-
Phenotypic and genotypic comparisons of CCR5- and CXCR4-tropic human immunodeficiency virus type 1 biological clones isolated from subtype C-infected individuals
-
Pollakis G, Abebe A, Kliphuis A, Chalaby MI, Bakker M, Mengistu Y, et al. Phenotypic and genotypic comparisons of CCR5- and CXCR4-tropic human immunodeficiency virus type 1 biological clones isolated from subtype C-infected individuals. J Virol 2004;78:2841-2852.
-
(2004)
J Virol
, vol.78
, pp. 2841-2852
-
-
Pollakis, G.1
Abebe, A.2
Kliphuis, A.3
Chalaby, M.I.4
Bakker, M.5
Mengistu, Y.6
-
8
-
-
10744231634
-
Improved coreceptor usage prediction and genotypic monitoring of R5-to-X4 transition by motif analysis of human immunodeficiency virus type 1 env V3 loop sequences
-
Jensen MA, Li FS, van't Wout AB, Nickle DC, Shriner D, He HX, et al. Improved coreceptor usage prediction and genotypic monitoring of R5-to-X4 transition by motif analysis of human immunodeficiency virus type 1 env V3 loop sequences. J Virol 2003; 77:13376-13388.
-
(2003)
J Virol
, vol.77
, pp. 13376-13388
-
-
Jensen, M.A.1
Li, F.S.2
van't Wout, A.B.3
Nickle, D.C.4
Shriner, D.5
He, H.X.6
-
10
-
-
33748996485
-
Molecular switch for alternative conformations of the HIV-1 V3 region: Implications for phenotype conversion
-
Rosen O, Sharon M, Quadt-AkabayovSR, AnglisterJ. Molecular switch for alternative conformations of the HIV-1 V3 region: implications for phenotype conversion. Proc Natl Acad Sci USA 2006;103:13950-13955.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 13950-13955
-
-
Rosen, O.1
Sharon, M.2
AkabayovSR, Q.3
AnglisterJ4
-
11
-
-
34247214426
-
Structural basis for coreceptor selectivity by the HIV type 1 V3 loop
-
Cardozo T, Kimura T, Philpott S, Weiser B, Burger H, Zolla-Pazner S. Structural basis for coreceptor selectivity by the HIV type 1 V3 loop. AIDS Res Hum Retroviruses 2007; 23:415-426.
-
(2007)
AIDS Res Hum Retroviruses
, vol.23
, pp. 415-426
-
-
Cardozo, T.1
Kimura, T.2
Philpott, S.3
Weiser, B.4
Burger, H.5
Zolla-Pazner, S.6
-
12
-
-
0028228751
-
Human immunodeficiency virus type 1 variants with increased replicative capacity develop during the asymptomatic stage before disease progression
-
Connor RI, Ho DD. Human immunodeficiency virus type 1 variants with increased replicative capacity develop during the asymptomatic stage before disease progression. J Virol 1994; 68:4400-4408.
-
(1994)
J Virol
, vol.68
, pp. 4400-4408
-
-
Connor, R.I.1
Ho, D.D.2
-
13
-
-
0031575431
-
Change in coreceptor use coreceptor use correlates with disease progression in HIV-1-infected individuals
-
Connor RI, Sheridan KE, Ceradini D, Choe S, Landau NR. Change in coreceptor use coreceptor use correlates with disease progression in HIV-1-infected individuals. J Exp Med 1997;185:621-628.
-
(1997)
J Exp Med
, vol.185
, pp. 621-628
-
-
Connor, R.I.1
Sheridan, K.E.2
Ceradini, D.3
Choe, S.4
Landau, N.R.5
-
14
-
-
0032929247
-
Conversion rate towards a syncytium-inducing (SI) phenotype during different stages of human immunodeficiency virus type 1 infection and prognostic value of SI phenotype for survival after AIDS diagnosis
-
Koot M, van Leeuwen R, de Goede RE, Keet IP, Danner S, Eeftinck Schattenkerk JK, et al. Conversion rate towards a syncytium-inducing (SI) phenotype during different stages of human immunodeficiency virus type 1 infection and prognostic value of SI phenotype for survival after AIDS diagnosis. J Infect Dis 1999;179:254-258.
-
(1999)
J Infect Dis
, vol.179
, pp. 254-258
-
-
Koot, M.1
van Leeuwen, R.2
de Goede, R.E.3
Keet, I.P.4
Danner, S.5
Eeftinck Schattenkerk, J.K.6
-
15
-
-
0032710838
-
Consistent viral evolutionary changes associated with the progression of human immunodeficiency virus type 1 infection
-
Shankarappa R, MargolickJB, GangeSJ, Rodrigo AG, Upchurch D, Farzadegan H, et al. Consistent viral evolutionary changes associated with the progression of human immunodeficiency virus type 1 infection. J Virol 1999;73:10489-10502.
-
(1999)
J Virol
, vol.73
, pp. 10489-10502
-
-
Shankarappa, R.1
Margolick, J.B.2
Gange, S.J.3
Rodrigo, A.G.4
Upchurch, D.5
Farzadegan, H.6
-
16
-
-
34548261959
-
Current V3 genotyping algorithms are inadequate for predicting X4 co-receptor usage in clinical isolates
-
Low AJ, Dong W, Chan D, Sing T, Swanstrom R, Jensen M, et al. Current V3 genotyping algorithms are inadequate for predicting X4 co-receptor usage in clinical isolates. Aids 2007;21: F17-F24.
-
(2007)
Aids
, vol.21
-
-
Low, A.J.1
Dong, W.2
Chan, D.3
Sing, T.4
Swanstrom, R.5
Jensen, M.6
-
17
-
-
24044455869
-
Genome sequencing in microfabricated high-density picolitre reactors
-
Margulies M, Egholm M, Altman WE, AttiyaS, BaderJS, Bemben LA, et al. Genome sequencing in microfabricated high-density picolitre reactors. Nature 2005;437:376-380.
-
(2005)
Nature
, vol.437
, pp. 376-380
-
-
Margulies, M.1
Egholm, M.2
Altman, W.E.3
Attiya, S.4
Bader, J.S.5
Bemben, L.A.6
-
18
-
-
34547643929
-
Characterization of mutation spectra with ultra-deep pyrose- quencing: Application to HIV-1 drug resistance
-
Wang C, Mitsuya Y, Gharizadeh B, Ronaghi M, Shafer RW. Characterization of mutation spectra with ultra-deep pyrose- quencing: application to HIV-1 drug resistance. Genome Res 2007;17:1195- 1201.
-
(2007)
Genome Res
, vol.17
, pp. 1195-1201
-
-
Wang, C.1
Mitsuya, Y.2
Gharizadeh, B.3
Ronaghi, M.4
Shafer, R.W.5
-
19
-
-
0032540905
-
A sequencing method based on real-time pyrophosphate
-
Ronaghi M, Uhlen M, Nyren P. A sequencing method based on real-time pyrophosphate. Science 1998;281:363, 365.
-
(1998)
Science
, vol.281
, Issue.363
, pp. 365
-
-
Ronaghi, M.1
Uhlen, M.2
Nyren, P.3
-
20
-
-
43149107930
-
Quality scores and SNP detection in sequencing- by-synthesis systems
-
Brockman W, Alvarez P, Young S, Garber M, Giannoukos G, Lee WL, et al. Quality scores and SNP detection in sequencing- by-synthesis systems. Genome Res 2008; 18:763-770.
-
(2008)
Genome Res
, vol.18
, pp. 763-770
-
-
Brockman, W.1
Alvarez, P.2
Young, S.3
Garber, M.4
Giannoukos, G.5
Lee, W.L.6
-
21
-
-
39649084637
-
Bioinformatics challenges of new sequencing technology
-
Pop M, Salzberg SL. Bioinformatics challenges of new sequencing technology. Trends Genet 2008; 24:142-149.
-
(2008)
Trends Genet
, vol.24
, pp. 142-149
-
-
Pop, M.1
Salzberg, S.L.2
-
22
-
-
34248157089
-
Data handling strategies for high throughput pyrosequencers
-
Trombetti GA, Bonnal RJ, Rizzi E, De Bellis G, Milanesi L. Data handling strategies for high throughput pyrosequencers. BMC Bioinformatics 2007;8 (Suppl 1):S22.
-
(2007)
BMC Bioinformatics
, vol.8
, Issue.SUPPL. 1
-
-
Trombetti, G.A.1
Bonnal, R.J.2
Rizzi, E.3
De Bellis, G.4
Milanesi, L.5
-
23
-
-
30744447460
-
Efficacy of short-term monotherapy with maraviroc, a new CCR5 antagonist, in patients infected with HIV-1
-
Fatkenheuer G, Pozniak AL, Johnson MA, Plettenberg A, Staszewski S, Hoepelman AI, et al. Efficacy of short-term monotherapy with maraviroc, a new CCR5 antagonist, in patients infected with HIV-1. Nat Med 2005;11:1170-1172.
-
(2005)
Nat Med
, vol.11
, pp. 1170-1172
-
-
Fatkenheuer, G.1
Pozniak, A.L.2
Johnson, M.A.3
Plettenberg, A.4
Staszewski, S.5
Hoepelman, A.I.6
-
24
-
-
0030801002
-
Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
-
Altschul SF, Madden TL, Schaffer AA, Zhang J, Zhang Z, Miller W, Lipman DJ. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res 1997; 25:3389-3402.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 3389-3402
-
-
Altschul, S.F.1
Madden, T.L.2
Schaffer, A.A.3
Zhang, J.4
Zhang, Z.5
Miller, W.6
Lipman, D.J.7
-
25
-
-
3042666256
-
MUSCLE: Multiple sequence alignment with high accuracy and high throughput
-
Edgar RC. MUSCLE: multiple sequence alignment with high accuracy and high throughput. Nucleic Acids Res 2004; 32: 1792-1797.
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 1792-1797
-
-
Edgar, R.C.1
-
27
-
-
0019887799
-
Identification of common molecular subsequences
-
Smith TF, Waterman MS. Identification of common molecular subsequences. J Mol Biol 1981;147:195-197.
-
(1981)
J Mol Biol
, vol.147
, pp. 195-197
-
-
Smith, T.F.1
Waterman, M.S.2
-
28
-
-
0242578620
-
A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood
-
Guindon S, Gascuel O. A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood. Syst Biol 2003;52:696-704.
-
(2003)
Syst Biol
, vol.52
, pp. 696-704
-
-
Guindon, S.1
Gascuel, O.2
-
29
-
-
0037423791
-
-
Nickle DC, Jensen MA, Gottlieb GS, Shriner D, Learn GH, Rodrigo AG, Mullins JI. Consensus and ancestral state HIV vaccines. Science 2003;299:1515-1518;author reply 1515-1518.
-
Nickle DC, Jensen MA, Gottlieb GS, Shriner D, Learn GH, Rodrigo AG, Mullins JI. Consensus and ancestral state HIV vaccines. Science 2003;299:1515-1518;author reply 1515-1518.
-
-
-
-
30
-
-
0031574072
-
The CLUSTAL-X windows interface: Flexible strategies for multiple sequence alignment aided by quality analysis tools
-
Thompson JD, Gibson TJ, Plewniak F, Jeanmougin F, Higgins DG. The CLUSTAL-X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res 1997; 25:4876-4882.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 4876-4882
-
-
Thompson, J.D.1
Gibson, T.J.2
Plewniak, F.3
Jeanmougin, F.4
Higgins, D.G.5
-
31
-
-
35648938560
-
CXCR4-using virus detected in patients receiving maraviroc in the Phase III studies MOTIVATE 1 and 2 originates from a pre-existing minority of CXCR4-using virus
-
Lewis M, Simpson P, Fransen S, Huang W, Whitcomb J, Mosley M, et al. CXCR4-using virus detected in patients receiving maraviroc in the Phase III studies MOTIVATE 1 and 2 originates from a pre-existing minority of CXCR4-using virus. Antiviral Ther 2007;12:S65-S165.
-
(2007)
Antiviral Ther
, vol.12
-
-
Lewis, M.1
Simpson, P.2
Fransen, S.3
Huang, W.4
Whitcomb, J.5
Mosley, M.6
-
32
-
-
36849083542
-
Bioinfor- matics prediction of HIV coreceptor usage
-
Lengauer T, Sander O, Sierra S, Thielen A, Kaiser R. Bioinfor- matics prediction of HIV coreceptor usage. Nat Biotechnol 2007;25:1407-1410.
-
(2007)
Nat Biotechnol
, vol.25
, pp. 1407-1410
-
-
Lengauer, T.1
Sander, O.2
Sierra, S.3
Thielen, A.4
Kaiser, R.5
-
33
-
-
43949118440
-
Coreceptor tropism can be influenced by amino acid substitutions in the gp41 transmembrane subunit of human immunodeficiency virus type 1 envelope protein
-
Huang W, Toma J, Fransen S, Stawiski E, Reeves JD, Whitcomb JM, et al. Coreceptor tropism can be influenced by amino acid substitutions in the gp41 transmembrane subunit of human immunodeficiency virus type 1 envelope protein. J Virol 2008; 82:5584-5593.
-
(2008)
J Virol
, vol.82
, pp. 5584-5593
-
-
Huang, W.1
Toma, J.2
Fransen, S.3
Stawiski, E.4
Reeves, J.D.5
Whitcomb, J.M.6
-
34
-
-
30344443665
-
Human immunodeficiency virus type 1 coreceptor switching: V1/V2 gain-of-fitness mutations compensate for V3 loss-of- fitness mutations
-
PastoreC, Nedellec R, Ramos A, Pontow S, Ratner L, Mosier DE. Human immunodeficiency virus type 1 coreceptor switching: V1/V2 gain-of-fitness mutations compensate for V3 loss-of- fitness mutations. J Virol 2006;80:750-758.
-
(2006)
J Virol
, vol.80
, pp. 750-758
-
-
Pastore, C.1
Nedellec, R.2
Ramos, A.3
Pontow, S.4
Ratner, L.5
Mosier, D.E.6
|