메뉴 건너뛰기




Volumn 21, Issue 14, 2007, Pages

Current V3 genotyping algorithms are inadequate for predicting X4 co-receptor usage in clinical isolates

Author keywords

CCR5; Co receptor; CXCR4; HIV; R5; V3; Viral phenotype; X4

Indexed keywords

CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CCR5 ANTAGONIST; CHEMOKINE RECEPTOR CXCR4; ENVELOPE PROTEIN; VIRUS PROTEIN;

EID: 34548261959     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/QAD.0b013e3282ef81ea     Document Type: Article
Times cited : (125)

References (38)
  • 1
    • 15844419153 scopus 로고    scopus 로고
    • Identification of a major co-receptor for primary isolates of HIV-1
    • Deng H, Liu R, Ellmeier W, Choe S, Unutmaz D, Burkhart M, et al. Identification of a major co-receptor for primary isolates of HIV-1. Nature 1996; 381:661-666.
    • (1996) Nature , vol.381 , pp. 661-666
    • Deng, H.1    Liu, R.2    Ellmeier, W.3    Choe, S.4    Unutmaz, D.5    Burkhart, M.6
  • 2
  • 3
    • 0030002637 scopus 로고    scopus 로고
    • HIV-1 entry cofactor: Functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor
    • Feng Y, Broder CC, Kennedy PE, Berger EA. HIV-1 entry cofactor: Functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science 1996; 272:872-877.
    • (1996) Science , vol.272 , pp. 872-877
    • Feng, Y.1    Broder, C.C.2    Kennedy, P.E.3    Berger, E.A.4
  • 4
    • 0742325043 scopus 로고    scopus 로고
    • The CCR5 and CXCR4 coreceptors-central to understanding the transmission and pathogenesis of human immunodeficiency virus type 1 infection
    • Moore JP, Kitchen SG, Pugach P, Zack JA. The CCR5 and CXCR4 coreceptors-central to understanding the transmission and pathogenesis of human immunodeficiency virus type 1 infection. AIDS Res Hum Retroviruses 2004; 20:111-126.
    • (2004) AIDS Res Hum Retroviruses , vol.20 , pp. 111-126
    • Moore, J.P.1    Kitchen, S.G.2    Pugach, P.3    Zack, J.A.4
  • 5
    • 0031684753 scopus 로고    scopus 로고
    • Chemokine coreceptor usage by diverse primary isolates of human immunodeficiency virus type 1
    • Zhang L, He T, Huang Y, Chen Z, Guo Y, Wu S, et al. Chemokine coreceptor usage by diverse primary isolates of human immunodeficiency virus type 1. J Virol 1998; 72:9307-9312.
    • (1998) J Virol , vol.72 , pp. 9307-9312
    • Zhang, L.1    He, T.2    Huang, Y.3    Chen, Z.4    Guo, Y.5    Wu, S.6
  • 6
    • 0026070668 scopus 로고
    • Monocytotropic human immunodeficiency virus type 1 (HIV-1) variants detectable in all stages of HIV-1 infection lack T-cell line tropism and syncytium-inducing ability in primary T-cell culture
    • Schuitemaker H, Kootstra NA, de Goede RE, de Wolf F, Miedema F, Tersmette M. Monocytotropic human immunodeficiency virus type 1 (HIV-1) variants detectable in all stages of HIV-1 infection lack T-cell line tropism and syncytium-inducing ability in primary T-cell culture. J Virol 1991; 65:356-363.
    • (1991) J Virol , vol.65 , pp. 356-363
    • Schuitemaker, H.1    Kootstra, N.A.2    de Goede, R.E.3    de Wolf, F.4    Miedema, F.5    Tersmette, M.6
  • 7
    • 0026600926 scopus 로고
    • Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: Progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population
    • Schuitemaker H, Koot M, Kootstra NA, Dercksen MW, de Goede RE, van Steenwijk RP, et al. Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: Progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population. J Virol 1992; 66:1354-1360.
    • (1992) J Virol , vol.66 , pp. 1354-1360
    • Schuitemaker, H.1    Koot, M.2    Kootstra, N.A.3    Dercksen, M.W.4    de Goede, R.E.5    van Steenwijk, R.P.6
  • 8
    • 0024536114 scopus 로고
    • Evidence for a role of virulent human immunodeficiency virus (HIV) variants in the pathogenesis of acquired immunodeficiency syndrome: Studies on sequential HIV isolates
    • Tersmette M, Gruters RA, de Wolf F, de Goede RE, Lange JM, Schellekens PT, et al. Evidence for a role of virulent human immunodeficiency virus (HIV) variants in the pathogenesis of acquired immunodeficiency syndrome: Studies on sequential HIV isolates. J Virol 1989; 63:2118-2125.
    • (1989) J Virol , vol.63 , pp. 2118-2125
    • Tersmette, M.1    Gruters, R.A.2    de Wolf, F.3    de Goede, R.E.4    Lange, J.M.5    Schellekens, P.T.6
  • 9
    • 0027537480 scopus 로고
    • Prognostic value of HIV-1 syncytium-inducing phenotype for rate of CD4+ cell depletion and progression to AIDS
    • Koot M, Keet IP, Vos AH, de Goede RE, Roos MT, Coutinho RA, et al. Prognostic value of HIV-1 syncytium-inducing phenotype for rate of CD4+ cell depletion and progression to AIDS. Ann Intern Med 1993; 118:681-688.
    • (1993) Ann Intern Med , vol.118 , pp. 681-688
    • Koot, M.1    Keet, I.P.2    Vos, A.H.3    de Goede, R.E.4    Roos, M.T.5    Coutinho, R.A.6
  • 10
    • 33749839996 scopus 로고    scopus 로고
    • Safety and efficacy of maraviroc, a novel CCR5 antagonist, when used in combination with optimized background therapy for the treatment of antiretroviral-experiences subjects infected with dual/mixed-tropic HIV-1: 24-week results of a phase 2b exploratory trial
    • August 13-18, Toronto, Ontario, Canada, Abstract THLB0215
    • Mayer H, Van der Ryst E, Saag M, Clotet G, Fätkenheuer N, Clumeck N, et al. Safety and efficacy of maraviroc, a novel CCR5 antagonist, when used in combination with optimized background therapy for the treatment of antiretroviral-experiences subjects infected with dual/mixed-tropic HIV-1: 24-week results of a phase 2b exploratory trial. XVI International AIDS Conference, August 13-18, Toronto, Ontario, Canada, 2006 [Abstract THLB0215].
    • (2006) XVI International AIDS Conference
    • Mayer, H.1    Van der Ryst, E.2    Saag, M.3    Clotet, G.4    Fätkenheuer, N.5    Clumeck, N.6
  • 11
    • 34249075565 scopus 로고    scopus 로고
    • Efficacy and Safety of maraviroc plus optimized background therapy in viremic, ART-experienced patients infected with CCR5-tropic HIV-1 in Europe, Australia, and North America: 24-week results
    • February 25-28, Los Angeles, California, USA, Abstract 104aLB
    • Nelson M, Fätkenheuer N, Konourina I, Lazzarin A, Clumeck N, Horban A, et al. Efficacy and Safety of maraviroc plus optimized background therapy in viremic, ART-experienced patients infected with CCR5-tropic HIV-1 in Europe, Australia, and North America: 24-week results. 14th Conference on Retroviruses and Opportunistic Infections, February 25-28, Los Angeles, California, USA, 2007 [Abstract 104aLB].
    • (2007) 14th Conference on Retroviruses and Opportunistic Infections
    • Nelson, M.1    Fätkenheuer, N.2    Konourina, I.3    Lazzarin, A.4    Clumeck, N.5    Horban, A.6
  • 12
    • 34249089383 scopus 로고    scopus 로고
    • Efficacy and safety of maraviroc plus optimized background therapy in viremic ART-experienced patients infected with CCR5-tropic HIV-1: 24-week results of a phase 2b/3 Study in the US and Canada
    • February 25-28, Los Angeles, California, USA, Abstract 104bLB
    • Lalezari J, Goodrich J, DeJesus E, Lampiris H, Gulick R, Saag M, et al. Efficacy and safety of maraviroc plus optimized background therapy in viremic ART-experienced patients infected with CCR5-tropic HIV-1: 24-week results of a phase 2b/3 Study in the US and Canada. 14th Conference on Retroviruses and Opportunistic Infections, February 25-28, Los Angeles, California, USA, 2007 [Abstract 104bLB].
    • (2007) 14th Conference on Retroviruses and Opportunistic Infections
    • Lalezari, J.1    Goodrich, J.2    DeJesus, E.3    Lampiris, H.4    Gulick, R.5    Saag, M.6
  • 13
    • 33846623260 scopus 로고    scopus 로고
    • Development and characterization of a novel single-cycle recombinant-virus assay to determine human immunodeficiency virus type 1 coreceptor tropism
    • Whitcomb JM, Huang W, Fransen S, Limoli K, Toma J, Wrin T, et al. Development and characterization of a novel single-cycle recombinant-virus assay to determine human immunodeficiency virus type 1 coreceptor tropism. Antimicrob Agents Chemother 2007; 51:566-575.
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 566-575
    • Whitcomb, J.M.1    Huang, W.2    Fransen, S.3    Limoli, K.4    Toma, J.5    Wrin, T.6
  • 14
    • 0034749279 scopus 로고    scopus 로고
    • Determination of coreceptor usage of human immunodeficiency virus type 1 from patient plasma samples by using a recombinant phenotypic assay
    • Trouplin V, Salvatori F, Cappello F, Obry V, Brelot A, Heveker N, et al. Determination of coreceptor usage of human immunodeficiency virus type 1 from patient plasma samples by using a recombinant phenotypic assay. J Virol 2001; 75:251-259.
    • (2001) J Virol , vol.75 , pp. 251-259
    • Trouplin, V.1    Salvatori, F.2    Cappello, F.3    Obry, V.4    Brelot, A.5    Heveker, N.6
  • 15
    • 33847053906 scopus 로고    scopus 로고
    • Determining human immunodeficiency virus coreceptor use in a clinical setting: Degree of correlation between two phenotypic assays and a bioinformatic model
    • Skrabal K, Low AJ, Dong W, Sing T, Cheung PK, Mammano F, et al. Determining human immunodeficiency virus coreceptor use in a clinical setting: Degree of correlation between two phenotypic assays and a bioinformatic model. J Clin Microbiol 2007; 45:279-284.
    • (2007) J Clin Microbiol , vol.45 , pp. 279-284
    • Skrabal, K.1    Low, A.J.2    Dong, W.3    Sing, T.4    Cheung, P.K.5    Mammano, F.6
  • 16
    • 0026702003 scopus 로고
    • Minimal requirements for the human immunodeficiency virus type 1 V3 domain to support the syncytium-inducing phenotype: Analysis by single amino acid substitution
    • De Jong JJ, De Ronde A, Keulen W, Tersmette M, Goudsmit J. Minimal requirements for the human immunodeficiency virus type 1 V3 domain to support the syncytium-inducing phenotype: Analysis by single amino acid substitution. J Virol 1992; 66:6777-6780.
    • (1992) J Virol , vol.66 , pp. 6777-6780
    • De Jong, J.J.1    De Ronde, A.2    Keulen, W.3    Tersmette, M.4    Goudsmit, J.5
  • 17
    • 12144291059 scopus 로고    scopus 로고
    • Clinical and immunological impact of HIV envelope V3 sequence variation after starting initial triple antiretroviral therapy
    • Brumme ZL, Dong WW, Yip B, Wynhoven B, Hoffman NG, Swanstrom R, et al. Clinical and immunological impact of HIV envelope V3 sequence variation after starting initial triple antiretroviral therapy. AIDS 2004; 18:F1-F9.
    • (2004) AIDS , vol.18
    • Brumme, Z.L.1    Dong, W.W.2    Yip, B.3    Wynhoven, B.4    Hoffman, N.G.5    Swanstrom, R.6
  • 18
    • 0038637409 scopus 로고    scopus 로고
    • Predicting HIV-1 coreceptor usage with sequence analysis
    • Jensen MA, van 't Wout AB. Predicting HIV-1 coreceptor usage with sequence analysis. AIDS Rev 2003; 5:104-112.
    • (2003) AIDS Rev , vol.5 , pp. 104-112
    • Jensen, M.A.1    van 't Wout, A.B.2
  • 19
    • 22544456536 scopus 로고    scopus 로고
    • Molecular and clinical epidemiology of CXCR4-using HIV-1 in a large population of antiretroviral-naive individuals
    • Brumme ZL, Goodrich J, Mayer HB, Brumme CJ, Henrick BM, Wynhoven B, et al. Molecular and clinical epidemiology of CXCR4-using HIV-1 in a large population of antiretroviral-naive individuals. J Infect Dis 2005; 192:466-474.
    • (2005) J Infect Dis , vol.192 , pp. 466-474
    • Brumme, Z.L.1    Goodrich, J.2    Mayer, H.B.3    Brumme, C.J.4    Henrick, B.M.5    Wynhoven, B.6
  • 20
    • 0028950499 scopus 로고
    • Simple determination of human immunodeficiency virus type 1 syncytium-inducing V3 genotype by PCR
    • Fouchier RA, Brouwer M, Broersen SM, Schuitemaker H. Simple determination of human immunodeficiency virus type 1 syncytium-inducing V3 genotype by PCR. J Clin Microbiol 1995; 33:906-911.
    • (1995) J Clin Microbiol , vol.33 , pp. 906-911
    • Fouchier, R.A.1    Brouwer, M.2    Broersen, S.M.3    Schuitemaker, H.4
  • 21
    • 0035884899 scopus 로고    scopus 로고
    • Improved success of phenotype prediction of the human immunodeficiency virus type 1 from envelope variable loop 3 sequence using neural networks
    • Resch W, Hoffman N, Swanstrom R. Improved success of phenotype prediction of the human immunodeficiency virus type 1 from envelope variable loop 3 sequence using neural networks. Virology 2001; 288:51-62.
    • (2001) Virology , vol.288 , pp. 51-62
    • Resch, W.1    Hoffman, N.2    Swanstrom, R.3
  • 24
    • 10744231634 scopus 로고    scopus 로고
    • Improved coreceptor usage prediction and genotypic monitoring of R5-to-X4 transition by motif analysis of human immunodeficiency virus type 1 env V3 loop sequences
    • Jensen MA, Li FS, van 't Wout AB, Nickle DC, Shriner D, He HX, et al. Improved coreceptor usage prediction and genotypic monitoring of R5-to-X4 transition by motif analysis of human immunodeficiency virus type 1 env V3 loop sequences. J Virol 2003; 77:13376-13388.
    • (2003) J Virol , vol.77 , pp. 13376-13388
    • Jensen, M.A.1    Li, F.S.2    van 't Wout, A.B.3    Nickle, D.C.4    Shriner, D.5    He, H.X.6
  • 25
    • 0035965633 scopus 로고    scopus 로고
    • Rates of disease progression by baseline CD4 cell count and viral load after initiating triple-drug therapy
    • Hogg RS, Yip B, Chan KJ, Wood E, Craib KJ, O'Shaughnessy MV, et al. Rates of disease progression by baseline CD4 cell count and viral load after initiating triple-drug therapy. JAMA 2001; 286:2568-2577.
    • (2001) JAMA , vol.286 , pp. 2568-2577
    • Hogg, R.S.1    Yip, B.2    Chan, K.J.3    Wood, E.4    Craib, K.J.5    O'Shaughnessy, M.V.6
  • 26
    • 3042666256 scopus 로고    scopus 로고
    • MUSCLE: Multiple sequence alignment with high accuracy and high throughput
    • Edgar RC. MUSCLE: Multiple sequence alignment with high accuracy and high throughput. Nucleic Acids Res 2004; 32:1792-1797.
    • (2004) Nucleic Acids Res , vol.32 , pp. 1792-1797
    • Edgar, R.C.1
  • 27
    • 33847049582 scopus 로고    scopus 로고
    • Immunologic markers improve genotypic prediction of HIV-1 co-receptor usage
    • December 2-3, Bethesda, Maryland, USA, Abstract 30
    • Sing T, Harrigan R, Beerenwinkel N, Daumer M, Kaiser R, Low A, et al. Immunologic markers improve genotypic prediction of HIV-1 co-receptor usage. Int Workshop on Targeting HIV Entry, December 2-3, Bethesda, Maryland, USA 2005 [Abstract 30].
    • (2005) Int Workshop on Targeting HIV Entry
    • Sing, T.1    Harrigan, R.2    Beerenwinkel, N.3    Daumer, M.4    Kaiser, R.5    Low, A.6
  • 29
    • 34548218926 scopus 로고    scopus 로고
    • Immunologic, virologic, and genotypic correlates of phenotypic CCR5/CXCR4 co-receptor usage assay readouts in a large panel of clinically derived isolates
    • February 25-28, Los Angeles, California, USA, Abstract 177
    • Low AJ, Brumme CJ, Brumme ZL, Hogg RS, Montaner JS, Harrigan PR, et al. Immunologic, virologic, and genotypic correlates of phenotypic CCR5/CXCR4 co-receptor usage assay readouts in a large panel of clinically derived isolates. 14th Conference on Retroviruses and Opportunistic Infections, February 25-28, Los Angeles, California, USA, 2007 [Abstract 177].
    • (2007) 14th Conference on Retroviruses and Opportunistic Infections
    • Low, A.J.1    Brumme, C.J.2    Brumme, Z.L.3    Hogg, R.S.4    Montaner, J.S.5    Harrigan, P.R.6
  • 30
    • 0027916595 scopus 로고
    • Quantitative detection of HIV-1 drug resistance mutations by automated DNA sequencing
    • Larder BA, Kohli A, Kellam P, Kemp SD, Kronick M, Henfrey RD. Quantitative detection of HIV-1 drug resistance mutations by automated DNA sequencing. Nature 1993; 365:671-673.
    • (1993) Nature , vol.365 , pp. 671-673
    • Larder, B.A.1    Kohli, A.2    Kellam, P.3    Kemp, S.D.4    Kronick, M.5    Henfrey, R.D.6
  • 32
    • 0033037358 scopus 로고    scopus 로고
    • Worldwide evaluation of DNA sequencing approaches for identification of drug resistance mutations in the human immunodeficiency virus type 1 reverse transcriptase
    • Schuurman R, Demeter L, Reichelderfer P, Tijnagel J, de Groot T, Boucher C. Worldwide evaluation of DNA sequencing approaches for identification of drug resistance mutations in the human immunodeficiency virus type 1 reverse transcriptase. J Clin Microbiol 1999; 37:2291-2296.
    • (1999) J Clin Microbiol , vol.37 , pp. 2291-2296
    • Schuurman, R.1    Demeter, L.2    Reichelderfer, P.3    Tijnagel, J.4    de Groot, T.5    Boucher, C.6
  • 33
    • 0032733696 scopus 로고    scopus 로고
    • Phenotypic assays and sequencing are less sensitive than point mutation assays for detection of resistance in mixed HIV-1 genotypic populations
    • Van Laethem K, Van Vaerenbergh K, Schmit JC, Sprecher S, Hermans P, De Vroey V, et al. Phenotypic assays and sequencing are less sensitive than point mutation assays for detection of resistance in mixed HIV-1 genotypic populations. J Acquir Immune Defic Syndr 1999; 22:107-118.
    • (1999) J Acquir Immune Defic Syndr , vol.22 , pp. 107-118
    • Van Laethem, K.1    Van Vaerenbergh, K.2    Schmit, J.C.3    Sprecher, S.4    Hermans, P.5    De Vroey, V.6
  • 34
    • 34548288216 scopus 로고    scopus 로고
    • Evaluation of an ultra-deep sequencing method to identify minority sequence variants in the HIV-1 env gene from clinical samples
    • February 25-28, Los Angeles, California, USA, Abstract 680
    • Lewis M, James I, Braverman M, Desany B, Jarvie T, Penny M, et al. Evaluation of an ultra-deep sequencing method to identify minority sequence variants in the HIV-1 env gene from clinical samples. 14th Conference on Retroviruses and Opportunistic Infections, February 25-28, Los Angeles, California, USA, 2007 [Abstract 680].
    • (2007) 14th Conference on Retroviruses and Opportunistic Infections
    • Lewis, M.1    James, I.2    Braverman, M.3    Desany, B.4    Jarvie, T.5    Penny, M.6
  • 35
    • 0033865498 scopus 로고    scopus 로고
    • Patterns of changes in human immunodeficiency virus type 1 V3 sequence populations late in infection
    • Nelson JA, Baribaud F, Edwards T, Swanstrom R. Patterns of changes in human immunodeficiency virus type 1 V3 sequence populations late in infection. J Virol 2000; 74:8494-8501.
    • (2000) J Virol , vol.74 , pp. 8494-8501
    • Nelson, J.A.1    Baribaud, F.2    Edwards, T.3    Swanstrom, R.4
  • 36
    • 34548277206 scopus 로고    scopus 로고
    • CXCR4-using virus detected in patients receiving maraviroc in the Phase III studies MOTIVATE 1 and 2 originates from a preexisting minority of CXCR4-using virus
    • June 12-16, Barbados, West Indies, Abstract 56
    • Lewis M, Simpson P, Francen S, Huang W, Whitcomb J, Mosley M, et al. CXCR4-using virus detected in patients receiving maraviroc in the Phase III studies MOTIVATE 1 and 2 originates from a preexisting minority of CXCR4-using virus. 16th International HIV Drug Resistance Workshop, June 12-16, Barbados, West Indies, 2007 [Abstract 56].
    • (2007) 16th International HIV Drug Resistance Workshop
    • Lewis, M.1    Simpson, P.2    Francen, S.3    Huang, W.4    Whitcomb, J.5    Mosley, M.6
  • 37
    • 34548215977 scopus 로고    scopus 로고
    • A sensitive assay for the determination of viral tropism suitable for clinical management of HIV subtype B and non-B infected individuals treated with coreceptor antagonists: PHENOSCRIPT® ENV
    • June 12-16, Barbados, West Indies, Abstract 147
    • Roulet V, Faudon J-L, Rochas S, Labernardiere J-L, Mammano F, Level-Binay S, et al. A sensitive assay for the determination of viral tropism suitable for clinical management of HIV subtype B and non-B infected individuals treated with coreceptor antagonists: PHENOSCRIPT® ENV. 16th International HIV Drug Resistance Workshop, June 12-16, Barbados, West Indies, 2007 [Abstract 147].
    • (2007) 16th International HIV Drug Resistance Workshop
    • Roulet, V.1    Faudon, J.-L.2    Rochas, S.3    Labernardiere, J.-L.4    Mammano, F.5    Level-Binay, S.6
  • 38
    • 34548247894 scopus 로고    scopus 로고
    • Detection limit of X4 minority virus in abundant R5-tropic virus populations in standard genotypic and phenotypic assays
    • June 12-16, Barbados, West Indies, Abstract 139
    • Vandenbroucke I, Van Eygen V, Rondelez E, Van Baelen K, Styver LJ. Detection limit of X4 minority virus in abundant R5-tropic virus populations in standard genotypic and phenotypic assays. 16th International HIV Drug Resistance Workshop, June 12-16, Barbados, West Indies, 2007 [Abstract 139].
    • (2007) 16th International HIV Drug Resistance Workshop
    • Vandenbroucke, I.1    Van Eygen, V.2    Rondelez, E.3    Van Baelen, K.4    Styver, L.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.