메뉴 건너뛰기




Volumn 460, Issue 7253, 2009, Pages 400-404

A reevaluation of X-irradiation-induced phocomelia and proximodistal limb patterning

Author keywords

[No Author keywords available]

Indexed keywords

BONE; DISEASE INCIDENCE; DRUG; IRRADIATION; LIMB; MOLECULAR ANALYSIS; TEMPORAL ANALYSIS; TOXICOLOGY; X-RAY;

EID: 67650945014     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature08117     Document Type: Article
Times cited : (55)

References (30)
  • 1
    • 49749219257 scopus 로고
    • Thalidomide and congenital abnormalities
    • Lenz, W. Thalidomide and congenital abnormalities. Lancet 279, 45-46 (1962).
    • (1962) Lancet , vol.279 , pp. 45-46
    • Lenz, W.1
  • 2
    • 21344439461 scopus 로고
    • Thalidomide and congenital limb abnormalities
    • Toms, D. Thalidomide and congenital limb abnormalities. Lancet 280, 400-401 (1962).
    • (1962) Lancet , vol.280 , pp. 400-401
    • Toms, D.1
  • 3
    • 0343905813 scopus 로고
    • The relation of development status of limb formation of X-radiation sensitivity in chick embryos. I. Groso study
    • Goff, R. A. The relation of development status of limb formation of X-radiation sensitivity in chick embryos. I. Groso study. J. Exp. Zool. 151, 177-200 (1962).
    • (1962) J. Exp. Zool , vol.151 , pp. 177-200
    • Goff, R.A.1
  • 4
    • 34250790876 scopus 로고
    • Developpement de l'ebauche des Membres apres traitement a l'yperite azotee, irradiation aux rayons X et culture in vitro. Etude comparative chez l'embryon de poulet
    • Pinot, M. Developpement de l'ebauche des Membres apres traitement a l'yperite azotee, irradiation aux rayons X et culture in vitro. Etude comparative chez l'embryon de poulet. Annal. Embryol. Morphog. 3, 215-234 (1970).
    • (1970) Annal. Embryol. Morphog , vol.3 , pp. 215-234
    • Pinot, M.1
  • 5
    • 0018656951 scopus 로고
    • The effect of cell killing by X-irradiation on pattern formation in the chick limb
    • Wolpert, L., Tickle, C. & Sampford, M. The effect of cell killing by X-irradiation on pattern formation in the chick limb. J. Embryol. Exp. Morphol. 50, 175-193 (1979).
    • (1979) J. Embryol. Exp. Morphol , vol.50 , pp. 175-193
    • Wolpert, L.1    Tickle, C.2    Sampford, M.3
  • 6
    • 0032569854 scopus 로고    scopus 로고
    • A developmental model for thalidomide defects
    • Tabin, C. J. A developmental model for thalidomide defects. Nature 396, 322-323 (1998).
    • (1998) Nature , vol.396 , pp. 322-323
    • Tabin, C.J.1
  • 7
    • 0015803611 scopus 로고
    • Positional information in chick limb morphogenesis
    • Summerbell, D., Lewis, J. H. & Wolpert, L. Positional information in chick limb morphogenesis. Nature 244, 492-496 (1973).
    • (1973) Nature , vol.244 , pp. 492-496
    • Summerbell, D.1    Lewis, J.H.2    Wolpert, L.3
  • 8
    • 0027436330 scopus 로고
    • FGF-4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb
    • Niswander, L., Tickle, C., Vogel, A., Booth, I. & Martin, G. R. FGF-4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb. Cell 75, 579-587 (1993).
    • (1993) Cell , vol.75 , pp. 579-587
    • Niswander, L.1    Tickle, C.2    Vogel, A.3    Booth, I.4    Martin, G.R.5
  • 9
    • 0028149891 scopus 로고
    • A positive feedback loop coordinates growth and patterning in the vertebrate limb
    • Niswander, L., Jeffrey, S., Martin, G. R. & Tickle, C. A positive feedback loop coordinates growth and patterning in the vertebrate limb. Nature 371, 609-612 (1994).
    • (1994) Nature , vol.371 , pp. 609-612
    • Niswander, L.1    Jeffrey, S.2    Martin, G.R.3    Tickle, C.4
  • 10
    • 0028569704 scopus 로고
    • Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud
    • Laufer, E., Nelson, C. E., Johnson, R. L., Morgan, B. A. & Tabin, C. Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud. Cell 79, 993-1003 (1994).
    • (1994) Cell , vol.79 , pp. 993-1003
    • Laufer, E.1    Nelson, C.E.2    Johnson, R.L.3    Morgan, B.A.4    Tabin, C.5
  • 11
    • 0031571666 scopus 로고    scopus 로고
    • Chicken transcription factor AP-2: Cloning, expression and its role in outgrowth of facial prominences and limb buds
    • Shen, H. et al. Chicken transcription factor AP-2: cloning, expression and its role in outgrowth of facial prominences and limb buds. Dev. Biol. 188, 248-266 (1997).
    • (1997) Dev. Biol , vol.188 , pp. 248-266
    • Shen, H.1
  • 12
    • 34250710115 scopus 로고    scopus 로고
    • Rethinking the proximodistal axis of the vertebrate limb in the molecular era
    • Tabin, C. & Wolpert, L. Rethinking the proximodistal axis of the vertebrate limb in the molecular era. Genes Dev. 21, 1433-1442 (2007).
    • (2007) Genes Dev , vol.21 , pp. 1433-1442
    • Tabin, C.1    Wolpert, L.2
  • 13
    • 15844372073 scopus 로고    scopus 로고
    • Analysis of Hox gene expression in the chick limb bud
    • Nelson, C. E. et al. Analysis of Hox gene expression in the chick limb bud. Development 122, 1449-1466 (1996).
    • (1996) Development , vol.122 , pp. 1449-1466
    • Nelson, C.E.1
  • 14
    • 29244484430 scopus 로고    scopus 로고
    • Radiation and new molecular agents part I: Targeting ATM-ATR checkpoints, DNA repair, and the proteasome
    • Choudhury, A., Cuddihy, A. & Bristow, R. G. Radiation and new molecular agents part I: targeting ATM-ATR checkpoints, DNA repair, and the proteasome. Semin. Radiat. Oncol. 16, 51-58 (2006).
    • (2006) Semin. Radiat. Oncol , vol.16 , pp. 51-58
    • Choudhury, A.1    Cuddihy, A.2    Bristow, R.G.3
  • 15
    • 0036830491 scopus 로고    scopus 로고
    • The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6
    • Akiyama, H., Chaboissier, M. C., Martin, J. F., Schedl, A.& de Crombrugghe, B. The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6. Genes Dev. 16, 2813-2828 (2002).
    • (2002) Genes Dev , vol.16 , pp. 2813-2828
    • Akiyama, H.1    Chaboissier, M.C.2    Martin, J.F.3    Schedl, A.4    de Crombrugghe, B.5
  • 16
    • 0036682468 scopus 로고    scopus 로고
    • Functions of FGF signalling from the apical ectodermal ridge in limb development
    • Sun, X., Mariani, F. V. & Martin, G. R. Functions of FGF signalling from the apical ectodermal ridge in limb development. Nature 418, 501-508 (2002).
    • (2002) Nature , vol.418 , pp. 501-508
    • Sun, X.1    Mariani, F.V.2    Martin, G.R.3
  • 17
    • 0038011840 scopus 로고    scopus 로고
    • Deciphering skeletal patterning: Clues from the limb
    • Mariani, F. V. & Martin, G. R. Deciphering skeletal patterning: clues from the limb. Nature 423, 319-325 (2003).
    • (2003) Nature , vol.423 , pp. 319-325
    • Mariani, F.V.1    Martin, G.R.2
  • 18
    • 0010683434 scopus 로고
    • Effect of X-rays on the morphogenesis of the embryonic chick tibiotarsus
    • Biggers, J. D. & Gwatkin, R. B. Effect of X-rays on the morphogenesis of the embryonic chick tibiotarsus. Nature 202, 152-154 (1964).
    • (1964) Nature , vol.202 , pp. 152-154
    • Biggers, J.D.1    Gwatkin, R.B.2
  • 19
    • 34248223634 scopus 로고    scopus 로고
    • Specification of cell fate along the proximal-distal axis in the developing chick limb bud
    • Sato, K., Koizumi, Y., Takahashi, M., Kuroiwa, A. & Tamura, K. Specification of cell fate along the proximal-distal axis in the developing chick limb bud. Development 134, 1397-1406 (2007).
    • (2007) Development , vol.134 , pp. 1397-1406
    • Sato, K.1    Koizumi, Y.2    Takahashi, M.3    Kuroiwa, A.4    Tamura, K.5
  • 20
    • 0036682108 scopus 로고    scopus 로고
    • A re-examination of proximodistal patterning during vertebrate limb development
    • Dudley, A. T., Ros, M. A. & Tabin, C. J. A re-examination of proximodistal patterning during vertebrate limb development. Nature 418, 539-544 (2002).
    • (2002) Nature , vol.418 , pp. 539-544
    • Dudley, A.T.1    Ros, M.A.2    Tabin, C.J.3
  • 21
    • 0033786946 scopus 로고    scopus 로고
    • Opposing RA and FGF signals control proximodistal vertebrate limb development through regulation of Meis genes
    • Mercader, N. et al. Opposing RA and FGF signals control proximodistal vertebrate limb development through regulation of Meis genes. Development 127, 3961-3970 (2000).
    • (2000) Development , vol.127 , pp. 3961-3970
    • Mercader, N.1
  • 22
    • 34247607671 scopus 로고    scopus 로고
    • Thalidomide induces limb deformities by perturbing the Bmp/Dkk1/Wnt signaling pathway
    • Knobloch, J., Shaughnessy, J. D. Jr & Ruther, U. Thalidomide induces limb deformities by perturbing the Bmp/Dkk1/Wnt signaling pathway. FASEB J. 21, 1410-1421 (2007).
    • (2007) FASEB J , vol.21 , pp. 1410-1421
    • Knobloch, J.1    Shaughnessy Jr, J.D.2    Ruther, U.3
  • 23
    • 37849052222 scopus 로고    scopus 로고
    • Thalidomide induces limbanomalies by PTEN stabilization, Akt suppression, and stimulation of caspase-dependent cell death
    • Knobloch, J., Schmitz, I., Gotz, K., Schulze-Osthoff, K. & Ruther, U. Thalidomide induces limbanomalies by PTEN stabilization, Akt suppression, and stimulation of caspase-dependent cell death. Mol. Cell. Biol. 28, 529-538 (2008).
    • (2008) Mol. Cell. Biol , vol.28 , pp. 529-538
    • Knobloch, J.1    Schmitz, I.2    Gotz, K.3    Schulze-Osthoff, K.4    Ruther, U.5
  • 24
    • 66649093493 scopus 로고    scopus 로고
    • Thalidomide induces limb defects by preventing angiogenic outgrowth during early limb formation
    • Therapontos, C., Erskine, L., Gardner, E., Figg, W. & Vargesson, N. Thalidomide induces limb defects by preventing angiogenic outgrowth during early limb formation. Proc. Natl Acad. Sci. USA. 106, 8573-8578 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 8573-8578
    • Therapontos, C.1    Erskine, L.2    Gardner, E.3    Figg, W.4    Vargesson, N.5
  • 25
    • 0014597768 scopus 로고
    • Comparative study of the effects of nitrogen mustard on mesodermal and ectodermal limb bud components of chick embryos
    • Salzgeber, B. Comparative study of the effects of nitrogen mustard on mesodermal and ectodermal limb bud components of chick embryos. J. Embryol. Exp. Morphol. 22, 373-394 (1969).
    • (1969) J. Embryol. Exp. Morphol , vol.22 , pp. 373-394
    • Salzgeber, B.1
  • 26
    • 84979343902 scopus 로고
    • Ectodermal-mesodermal interactions in chick embryo limb buds treated with nitrogen mustard
    • Salzgeber, B. Ectodermal-mesodermal interactions in chick embryo limb buds treated with nitrogen mustard. Dev. Growth Differ. 17, 295-296 (1975).
    • (1975) Dev. Growth Differ , vol.17 , pp. 295-296
    • Salzgeber, B.1
  • 27
    • 0027445532 scopus 로고
    • Detection of messenger RNA by in situ hybridization to tissue sections and whole mounts
    • Wilkinson, D. G. & Nieto, M. A. Detection of messenger RNA by in situ hybridization to tissue sections and whole mounts. Methods Enzymol. 225, 361-373 (1993).
    • (1993) Methods Enzymol , vol.225 , pp. 361-373
    • Wilkinson, D.G.1    Nieto, M.A.2
  • 28
    • 0019126423 scopus 로고
    • Differential staining of cartilage and bone in whole mouse fetuses by alcian blue and alizarin red S
    • McLeod, M. J. Differential staining of cartilage and bone in whole mouse fetuses by alcian blue and alizarin red S. Teratology 22, 299-301 (1980).
    • (1980) Teratology , vol.22 , pp. 299-301
    • McLeod, M.J.1
  • 29
    • 0027760995 scopus 로고
    • Sonic hedgehog mediates the polarizing activity of the ZPA
    • Riddle, R. D., Johnson, R. L., Laufer, E. & Tabin, C. Sonic hedgehog mediates the polarizing activity of the ZPA. Cell 75, 1401-1416 (1993).
    • (1993) Cell , vol.75 , pp. 1401-1416
    • Riddle, R.D.1    Johnson, R.L.2    Laufer, E.3    Tabin, C.4
  • 30
    • 0032938895 scopus 로고    scopus 로고
    • Regulation and role of Sox9 in cartilage formation
    • Healy, C., Uwanogho, D. & Sharpe, P. T. Regulation and role of Sox9 in cartilage formation. Dev. Dyn. 215, 69-78 (1999).
    • (1999) Dev. Dyn , vol.215 , pp. 69-78
    • Healy, C.1    Uwanogho, D.2    Sharpe, P.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.