Differential expression of Candida dubliniensis-secreted aspartyl proteinase genes (CdSAP1-4) under different physiological conditions and during infection of a keratinocyte culture

FEMS Immunology and Medical Microbiology

Volumn 56, Issue 3, 2009, Pages 212-222

  Loaiza Loeza, Salomé ^a   Parra Ortega, Berenice ^a   Cancino Díaz, Juan Carlos ^a   Illades Aguiar, Berenice ^a   Hernández Rodríguez, César Hugo ^a   Villa Tanaca, Lourdes ^a  

^a INSTITUTO POLITÉCNICO NACIONAL   (Mexico)

Author keywords

Candida dubliniensis; E.C.3.4.23; Keratinocyte infection; SAP genes; Secreted aspartyl protease

Indexed keywords

ALBUMIN; ASPARTIC PROTEINASE; NITROGEN; PEPSTATIN; VIRULENCE FACTOR;

ARTICLE; BACTERIAL GENE; BACTERIAL GENOME; CANDIDA DUBLINIENSIS; CDSAP1 GENE; CDSAP10 GENE; CDSAP2 GENE; CDSAP3 GENE; CDSAP4 GENE; CDSAP7 GENE; CDSAP8 GENE; CDSAP9 GENE; CELL CULTURE; CELL DAMAGE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; KERATINOCYTE; MORPHOLOGY; MYCELIUM; NITROGEN METABOLISM; NONHUMAN; NUCLEOTIDE SEQUENCE; NUTRIENT; PRIORITY JOURNAL; SAP5 GENE; SAP6 GENE;

ASPARTIC ENDOPEPTIDASES; CANDIDA; CELL LINE; ENZYME INHIBITORS; FUNGAL PROTEINS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, FUNGAL; HUMANS; HYDROGEN-ION CONCENTRATION; KERATINOCYTES; PEPSTATINS; PHYLOGENY; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 67650723299     PISSN: 09288244     EISSN: 1574695X     Source Type: Journal    
DOI: 10.1111/j.1574-695X.2009.00570.x     Document Type: Article

References (34)

1. Albrecht A, Felk A, Pichova I et al 2006) Glycosylphosphatidylinositol- anchored proteases of Candida albicans target proteins necessary for both cellular processes and host-pathogen interactions. J Biol Chem 281 : 688 694.
2. Bautista-Muñoz C, Hernández-Rodríguez C Villa-Tanaca L (2005) Analysis and expression of STE13 gene encoding a putative X-prolyl-dipeptidyl aminopeptidase from Candida albicans. FEMS Immunol Med Mic 45 : 459 469. (Pubitemid 41247783)
3. Birnboim RC Doly J (1979) A rapid alkaline extraction procedure for screening recombinant plasmid DNA. Nucleic Acids Res 7 : 1513 1523.
4. Borg-von Zepellin M, Beggah S, Boggian K, Sanglard D Monod M (1998) The expression of the secreted aspartyl proteinases Sap4 to Sap6 from Candida albicans in murine macrophages. Mol Microbiol 28 : 543 554. (Pubitemid 28218399)
5. Calderone RA (2002) Introduction and historical perspectives. Candida and Candidiasis (Calderone RA, ed), pp. 3 12. ASM Press, Washington, DC.
6. Campanella JJ, Bitincka L Smalley J (2003) MatGAT: an application that generates similarity/identity matrices using protein or DNA sequences. BMC Bioinformatics 4 : 29.
7. Chen Y-C, Wu C-C, Chung W-L Lee F-J (2002) Differential secretion of Sap4-6 proteins in Candida albicans during hyphae formation. Microbiology 148 : 3743 3754. (Pubitemid 35414483)
8. el-Magrhabi EA, Dixon DM Burnett JW (1990) Characterization of Candida albicans epidermolytic proteases and their role in yeast-cell adherence to keratinocytes. Clin Exp Dermatol 15 : 183 191. (Pubitemid 20164899)
9. Falquet L, Pagni M, Bucher P, Hulo N, Sigrist CJ, Hofmann K Bairoch A (2002) The PROSITE database. Nucleic Acids Res 30 : 235 238.
10. Farrell RE (1998) RNA isolation strategies. RNA Methodologies. A Laboratory Guide for Isolation and Characterization, 2nd edn. pp. 92 94. Academic Press, New York.
11. Felk A, Kretschmar M, Albrecht A, Schaller M, Beinhauer S, Nichterlein T, Sanglard D, Korting HC, Schafer W Hube B (2002) Candida albicans hyphal formation and the expression of the Efg1-regulated proteinases Sap4 to Sap6 are required for the invasion of parenchymal organs. Infect Immun 70 : 3689 3700. (Pubitemid 34666008)
12. Galtier N, Gouy M Gautier C (1996) SEAVIEW and PHYLO-WIN: two graphic tools for sequence alignment and molecular phylogeny. Comput Appl Biosci 12 : 543 548.
13. Gilfillan G, Sullivan DJ, Haynes K, Parkinson T, Coleman DC Gow NAR (1998) Candida dubliniensis phylogeny and putative virulence factors. Microbiology 144 : 829 838. (Pubitemid 28187909)
14. Hall TA (1999) BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT. Nucleic Acids Symp 41 : 95 98.
15. Hillis DM Bull JJ (1993) An empirical test of bootstrapping as a method for assessing confidence in phylogenetic analysis. Syst Biol 42 : 182 192. (Pubitemid 23958220)
16. Hube B, Monod M, Schofield DA, Brown JP Gow NAR (1994) Expression of seven members of the gene family encoding secretory aspartyl proteinases in Candida albicans. Mol Microbiol 14 : 87 99. (Pubitemid 24312822)
17. Lermann U Morschhäuser J (2008) Secreted aspartic proteases are not required for invasion of reconstituted human epithelia by Candida albicans. Microbiology 154 : 3281 3295.
18. Loaiza-Loeza S, Parra-Ortega B, Bautista-Muñoz C, Casiano-Rosas C, Hernández-Rodríguez CH Villa-Tanaca L (2007) The proteolytic system of Candida dubliniensis. Am J Infect Dis 3 : 76 83. (Pubitemid 351699392)
19. Magasanik B Kaiser CA (2002) Nitrogen regulation in Saccharomyces cerevisiae. Gene 290 : 1 18. (Pubitemid 34615905)
20. Moran G, Stokes C, Thewes S, Hube B, Coleman DC Sullivan D (2004) Comparative genomics using Candida albicans DNA microarrays reveals absence and divergence of virulence-associated genes in Candida dubliniensis. Microbiology 150 : 3363 3382. (Pubitemid 39406206)
21. Naglik JR, Challacombe SJ Hube B (2003) Candida albicans secreted aspartyl proteinases in virulence and pathogenesis. Microbiol Mol Biol R 67 : 400 428. (Pubitemid 37122527)
22. Naglik JR, Moyes D, Makwana J et al 2008) Quantitative expression of the Candida albicans secreted aspartyl proteinase gene family in human oral and vaginal candidiasis. Microbiology 154 : 3266 3280.
23. Parra-Ortega B, Cruz-Torres H, Villa-Tanaca L Hernández- Rodríguez C (2009) Phylogeny and evolution of the aspartyl proteases family from clinically relevant Candida species. Mem I Oswaldo Cruz 104 : 505 512.
24. Pivarcsi A, Bodai L, Rethi B et al 2003) Expression and function of Toll-like receptors 2 and 4 in human keratinocytes. Int Immunol 15 : 721 730. (Pubitemid 36675803)
25. Schaller M, Borelli C, Korting HC Hube B (2005) Hydrolytic enzymes as virulence factors of Candida albicans. Mycoses 48 : 365 377. (Pubitemid 43942679)
26. Sebti A, Kiehn TE, Perlin D, Chaturvedi V, Wong M, Doney A, Park S Sepkowitz KA (2001) Candida dubliniensis at a cancer center. Clin Infect Dis 32 : 1034 1038. (Pubitemid 32299638)
27. Stokes C, Moran GP, Spiering MJ, Cole GT, Coleman DC Sullivan DJ (2007) Lower filamentation rates of Candida dubliniensis contribute to its lower virulence in comparison with Candida albicans. Fungal Genet Biol 44 : 920 931. (Pubitemid 47176936)
28. Sullivan DJ, Westerneng TJ, Haynes K, Bennett DE Coleman DC (1995) Candida dubliniensis sp. nov.: phenotypic and molecular characterization of a novel species associated with oral candidosis in HIV-infected individuals. Microbiology 141 : 1507 1521.
29. Sullivan DJ, Moran GP Coleman DC (2005) Candida dubliniensis ten years on. FEMS Microbiol Lett 253 : 9 17.
30. Tamura K, Dudley J, Nei M Kumar S (2007) MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. Mol Biol Evol 24 : 1596 1599. (Pubitemid 47236692)
31. Tavanti A, Pardini G, Campa D, Davini P Lupetti A (2004) Differential expression of secretory aspartyl proteinase genes (SAP1-10) in oral Candida albicans isolates with distinct karyotypes. J Clin Microbiol 42 : 4726 4734. (Pubitemid 39362395)
32. Thompson JD, Gibson TJ, Plewniak F, Jeanmougin F Higgins DG (1997) The ClustalX windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res 24 : 4876 4882. (Pubitemid 28022245)
33. Villar CC, Kashleva H, Nobile CJ, Mitchell AP Dongari-Batzoglou A (2007) Mucosal tissue invasion by Candida albicans is associated with E-cadherin degradation, mediated by transcription factor Rim101p and protease Sap5p. Infect Immun 75 : 2126 2135. (Pubitemid 46744298)
34. Willis AM, Coulter WA, Sullivan DJ, Coleman DC, Hayes JR, Bell PM Lamey PJ (2000) Isolation of C. dubliniensis from insulin-using diabetes mellitus patients. J Oral Pathol Med 29 : 86 90. (Pubitemid 30104872)