Retrospective analysis of relative parameter sensitivity in multi-generation reproductive toxicity studies

Reproductive Toxicology

Volumn 28, Issue 2, 2009, Pages 196-202

  Dang, Zhi Chao ^a   Rorije, Emiel ^a   Esch, Thijs Hogen ^a   Muller, André ^a   Hakkert, Betty C ^a   Piersma, Aldert H ^a  

^a NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

Author keywords

Classification and labelling; Continuous breeding; Fertility; LOAELs; OECD416; Offspring; Risk assessment; Sensitive reproductive endpoints

Indexed keywords

ARTICLE; BIRTH WEIGHT; BREEDING; FOLLOW UP; INFERTILITY; LITTER SIZE; METHODOLOGY; NONHUMAN; PRENATAL EXPOSURE; REPRODUCTIVE TOXICITY; RETROSPECTIVE STUDY; RISK ASSESSMENT; SCREENING TEST; SENSITIVITY AND SPECIFICITY; TESTIS WEIGHT; UROGENITAL SYSTEM PARAMETERS;

ANIMAL USE ALTERNATIVES; ANIMALS; BODY WEIGHT; DOSE-RESPONSE RELATIONSHIP, DRUG; EUROPEAN UNION; FEMALE; GENITALIA; MALE; MICE; ORGAN SIZE; RATS; REPRODUCTION; RETROSPECTIVE STUDIES; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; TOXICITY TESTS; XENOBIOTICS;

EID: 67650609864     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.reprotox.2009.04.009     Document Type: Article

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