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Volumn , Issue , 2005, Pages 329-424

Significance, reliability, and interpretation of developmental and reproductive toxicity study findings

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EID: 85123816417     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter
Times cited : (27)

References (176)
  • 1
    • 33745197215 scopus 로고    scopus 로고
    • The design, evaluation, and interpretation of developmental toxicity tests
    • Fan, A.M. and Chang, L.W., Eds., Marcel Dekker, New York
    • DeSesso, J.M., Harris, S.B., and Swain, S.M., The design, evaluation, and interpretation of developmental toxicity tests, in Toxicology and Risk Assessment: Principles, Methods, and Applications, Fan, A.M. and Chang, L.W., Eds., Marcel Dekker, New York, 1996, p. 227.
    • (1996) Toxicology and Risk Assessment: Principles, Methods, and Applications , pp. 227
    • DeSesso, J.M.1    Harris, S.B.2    Swain, S.M.3
  • 2
    • 85123817141 scopus 로고    scopus 로고
    • Data presentation in developmental toxicity studies: An aid to evaluation?
    • Hood. R.D., Ed., CRC Press, Boca Raton, FL, chap. 8
    • Palmer, A.K. and Ulbrich, B., Data presentation in developmental toxicity studies: an aid to evaluation? in Handbook of Developmental Toxicology, Hood. R.D., Ed., CRC Press, Boca Raton, FL, 1997, chap. 8.
    • (1997) Handbook of Developmental Toxicology
    • Palmer, A.K.1    Ulbrich, B.2
  • 7
    • 0015469123 scopus 로고
    • Drug testing for teratogenicity: Its implications, limitations and application to man
    • Klingberg, M.A., Abramovici, A., and Cheneke, J., Eds., Plenum Press, New York
    • Brent, R.L., Drug testing for teratogenicity: its implications, limitations and application to man, in Drugs and Fetal Development, Klingberg, M.A., Abramovici, A., and Cheneke, J., Eds., Plenum Press, New York, 1972, p. 31.
    • (1972) Drugs and Fetal Development , pp. 31
    • Brent, R.L.1
  • 9
    • 0038398055 scopus 로고
    • Relation of animal studies to the problem in man
    • Wilson, J.G. and Fraser, F.C., Eds., Plenum Press, New York
    • Fraser, F.C., Relation of animal studies to the problem in man, in Handbook of Teratology, Vol. 1, Wilson, J.G. and Fraser, F.C., Eds., Plenum Press, New York, 1979, p. 75.
    • (1979) Handbook of Teratology , vol.1 , pp. 75
    • Fraser, F.C.1
  • 10
    • 0018744998 scopus 로고
    • Is compensatory growth a complicating factor in mouse teratology?
    • Snow, M.H.L. and Tam, P.P.L., Is compensatory growth a complicating factor in mouse teratology?, Nature, 279, 555, 1979.
    • (1979) Nature , vol.279 , pp. 555
    • Snow, M.H.L.1    Tam, P.P.L.2
  • 11
    • 0003451003 scopus 로고
    • (Kimmel, C.A., Holson, J.F., Hogue, C.I., and Carlo, G.L., Eds.), NCTR Technical Report for Experiment No. Jefferson, AR, 1984
    • U.S. Food and Drug Administration, National Center for Toxicological Research, Reliability of Experimental Studies for Predicting Hazards to Human Development (Kimmel, C.A., Holson, J.F., Hogue, C.I., and Carlo, G.L., Eds.), NCTR Technical Report for Experiment No. 6015, Jefferson, AR, 1984.
    • (1984) Reliability of Experimental Studies for Predicting Hazards to Human Development
  • 13
    • 0029033201 scopus 로고
    • Detection of effects on male reproduction - a literature survey
    • Ulbrich, B. and Palmer, A.K., Detection of effects on male reproduction - a literature survey, J. Am. Coll. Toxicol., 14, 293, 1995.
    • (1995) J. Am. Coll. Toxicol , vol.14 , pp. 293
    • Ulbrich, B.1    Palmer, A.K.2
  • 14
    • 0028607250 scopus 로고
    • Adverse drug reactions
    • Clegg, J.A., Adverse drug reactions, Toxicol. Rev., 13, 235, 1994.
    • (1994) Toxicol. Rev , vol.13 , pp. 235
    • Clegg, J.A.1
  • 16
    • 0023876710 scopus 로고
    • Reproductive hazards in the workplace: What the practitioner needs to know about chemical exposures
    • Paul, M. and Himmelstein J., Reproductive hazards in the workplace: what the practitioner needs to know about chemical exposures, Obstet. Gynecol., 71, 921, 1988.
    • (1988) Obstet. Gynecol , vol.71 , pp. 921
    • Paul, M.1    Himmelstein, J.2
  • 18
    • 0012016098 scopus 로고
    • Physiology and toxicology of the male reproductive tract
    • Thomas, J.A., Korach, K.S., and McLachlan, J.A., Eds., Raven, New York
    • Waller, D.P., Killinger, J.M., Zaneveld, L.J.D., Physiology and toxicology of the male reproductive tract, in Endocrine Toxicology, Thomas, J.A., Korach, K.S., and McLachlan, J.A., Eds., Raven, New York, 1985, p. 269.
    • (1985) Endocrine Toxicology , pp. 269
    • Waller, D.P.1    Killinger, J.M.2    Zaneveld, L.J.D.3
  • 19
    • 0345473985 scopus 로고
    • Epidemiologic aspects of reproductive toxicology
    • 2nd ed., Witorsch, R.J., Ed., Raven Press
    • Scialli, A.R. and Lemasters, G.K., Epidemiologic aspects of reproductive toxicology, in Reproductive Toxicology, 2nd ed., Witorsch, R.J., Ed., Raven Press, 1995, p. 241.
    • (1995) Reproductive Toxicology , pp. 241
    • Scialli, A.R.1    Lemasters, G.K.2
  • 20
    • 0028856722 scopus 로고
    • Dibromochloropropane (DBCP): A 17-year reassessment of testicular function and reproductive performance
    • Potashnik, G. and Porath, A., Dibromochloropropane (DBCP): a 17-year reassessment of testicular function and reproductive performance, J. Occup. Environ. Med., 37, 1287, 1995.
    • (1995) J. Occup. Environ. Med , vol.37 , pp. 1287
    • Potashnik, G.1    Porath, A.2
  • 21
    • 85123816286 scopus 로고    scopus 로고
    • Dibromochloropropane: Epidemiological findings and current questions
    • Goldsmith, J.R., Dibromochloropropane: epidemiological findings and current questions, Ann. N. Y. Acad. Sci., 26, 837, 1997.
    • (1997) Ann. N. Y. Acad. Sci , vol.26 , pp. 837
    • Goldsmith, J.R.1
  • 23
    • 0345582770 scopus 로고    scopus 로고
    • Neuroendocrine control of female reproduction
    • Boekelheide, K., Chapin, R.E., Hoyer, P.B., and Harris, C., Eds., Elsevier, New York
    • Cooper, R.L., Neuroendocrine control of female reproduction, in Reproductive and Endocrine Toxicology (Comprehensive Toxicology, Vol. 10), Boekelheide, K., Chapin, R.E., Hoyer, P.B., and Harris, C., Eds., Elsevier, New York, 1997, p. 273.
    • (1997) Reproductive and Endocrine Toxicology (Comprehensive Toxicology) , vol.10 , pp. 273
    • Cooper, R.L.1
  • 24
    • 0032831037 scopus 로고    scopus 로고
    • The mammary tumor response in triazine-treated female rats: A threshold-mediated interaction with strain and species-specific reproductive senescence
    • Eldridge, J.C., Wetzel, L.T., Stevens, J.T., and Simpkins, J.W., The mammary tumor response in triazine-treated female rats: a threshold-mediated interaction with strain and species-specific reproductive senescence, Steroids, 64, 672, 1999.
    • (1999) Steroids , vol.64 , pp. 672
    • Eldridge, J.C.1    Wetzel, L.T.2    Stevens, J.T.3    Simpkins, J.W.4
  • 25
    • 0022922668 scopus 로고
    • Neuroendocrine control of reproductive function in the aging female rodent
    • Cooper, R.L., Goldman, J.M., and Rehnberg, G.L., Neuroendocrine control of reproductive function in the aging female rodent, J. Am. Geriatric Sci., 34, 735, 1986.
    • (1986) J. Am. Geriatric Sci , vol.34 , pp. 735
    • Cooper, R.L.1    Goldman, J.M.2    Rehnberg, G.L.3
  • 30
    • 85027472441 scopus 로고
    • Experimental intersexuality: The paradoxical effects of estrogens on the sexual development of the female rat
    • Green, R., Burrill, M., and Ivy, A., Experimental intersexuality: the paradoxical effects of estrogens on the sexual development of the female rat, Anat. Rec., 74, 429, 1939.
    • (1939) Anat. Rec , vol.74 , pp. 429
    • Green, R.1    Burrill, M.2    Ivy, A.3
  • 31
    • 0011768438 scopus 로고
    • Experimental intersexuality: Modification of sexual development of the white rat with synthetic estrogen
    • Green, R., Burrill, M., and Ivy, A., Experimental intersexuality: modification of sexual development of the white rat with synthetic estrogen, Proc. Soc. Exp. Biol. Med., 41, 169, 1939.
    • (1939) Proc. Soc. Exp. Biol. Med , vol.41 , pp. 169
    • Green, R.1    Burrill, M.2    Ivy, A.3
  • 32
    • 0015225140 scopus 로고
    • Adenocarcinoma of the vagina: Association of maternal stilbestrol therapy with tumor appearance in young women
    • Herbst, A.L., Ulfelder, H., and Poskanzer, D.C., Adenocarcinoma of the vagina: association of maternal stilbestrol therapy with tumor appearance in young women, N. Eng. J. Med., 284, 878, 1971.
    • (1971) N. Eng. J. Med , vol.284 , pp. 878
    • Herbst, A.L.1    Ulfelder, H.2    Poskanzer, D.C.3
  • 33
    • 0017654390 scopus 로고
    • Age-incidence and risk of diethyl-stilbestrol-related clear cell adenocarcinoma of the vagina and cervix
    • Herbst, A.L., Cole, P., Colton, T., Robboy, S.J., and Scully, R.E., Age-incidence and risk of diethyl-stilbestrol-related clear cell adenocarcinoma of the vagina and cervix, Am. J. Obstet. Gynecol., 128, 43, 1977.
    • (1977) Am. J. Obstet. Gynecol , vol.128 , pp. 43
    • Herbst, A.L.1    Cole, P.2    Colton, T.3    Robboy, S.J.4    Scully, R.E.5
  • 36
    • 0025162704 scopus 로고
    • Nonhuman primates and teratological research
    • Hendrickx, A.G. and Binkerd, P.E., Nonhuman primates and teratological research, J. Med. Primatol., 19, 81, 1990.
    • (1990) J. Med. Primatol , vol.19 , pp. 81
    • Hendrickx, A.G.1    Binkerd, P.E.2
  • 38
    • 84882745748 scopus 로고
    • U.S. Environmental Protection Agency, Office of Pesticide Programs. Proposed guidelines for registering pesticides in the United States; Hazard evaluation: Humans and domestic animals
    • U.S. Environmental Protection Agency, Office of Pesticide Programs. Proposed guidelines for registering pesticides in the United States; Hazard evaluation: Humans and domestic animals, Fed. Regist., 43, 37336, 1978.
    • (1978) Fed. Regist , vol.43 , pp. 37336
  • 39
    • 0001162208 scopus 로고
    • U.S. Environmental Protection Agency, Guidelines for developmental toxicity risk assessment; notice
    • U.S. Environmental Protection Agency, Guidelines for developmental toxicity risk assessment; notice, Fed Regist., 56, 63798, 1991.
    • (1991) Fed Regist , vol.56 , pp. 63798
  • 40
    • 0000211484 scopus 로고    scopus 로고
    • U.S. Environmental Protection Agency, Reproductive toxicity risk assessment guidelines; notice
    • U.S. Environmental Protection Agency, Reproductive toxicity risk assessment guidelines; notice, Fed. Regist., 61, 56274, 1996.
    • (1996) Fed. Regist , vol.61 , pp. 56274
  • 43
    • 0028206104 scopus 로고
    • Biologically-based dose-response modeling in developmental toxicology: Biochemical and cellular sequelae of 5-fluorouracil exposure in the developing rat
    • Shuey, D.L., Lau, C., Logsdon, T.R., Zucker, R.M., Elstein, K.H., Narotsky, M.G., Setxer, R.W., Kavlock, R.J., and Rogers, J.M., Biologically-based dose-response modeling in developmental toxicology: biochemical and cellular sequelae of 5-fluorouracil exposure in the developing rat, Toxicol. Appl Pharmacol., 126, 129, 1994.
    • (1994) Toxicol. Appl Pharmacol , vol.126 , pp. 129
    • Shuey, D.L.1    Lau, C.2    Logsdon, T.R.3    Zucker, R.M.4    Elstein, K.H.5    Narotsky, M.G.6    Setxer, R.W.7    Kavlock, R.J.8    Rogers, J.M.9
  • 44
    • 0018055581 scopus 로고
    • Utility of pharmacokinetics in designing toxicological protocols and improving interspecies extrapolation
    • Young, J.F. and Holson, J.F., Utility of pharmacokinetics in designing toxicological protocols and improving interspecies extrapolation, J. Environ. Pathol. Toxicol., 2, 169, 1978.
    • (1978) J. Environ. Pathol. Toxicol , vol.2 , pp. 169
    • Young, J.F.1    Holson, J.F.2
  • 45
    • 0028632926 scopus 로고
    • Pharmacokinetic determinants of embryotoxicity in rats associated with organic acids
    • Scott, Jr. W.J. Collins, M.D., and Nau, H., Pharmacokinetic determinants of embryotoxicity in rats associated with organic acids, Environ. Health Perspect., 102(Suppl. 11), 97, 1994.
    • (1994) Environ. Health Perspect , vol.102 , pp. 97
    • Scott, W.J.1    Collins, M.D.2    Nau, H.3
  • 46
    • 77957180190 scopus 로고
    • Dose-response assessment for developmental toxicity. I. Characterization of database and determination of no observed adverse effect levels
    • Faustman, E.M., Allen, B.C., Kavlock, R.J., and Kimmel, C.A., Dose-response assessment for developmental toxicity. I. Characterization of database and determination of no observed adverse effect levels, Fundam. Appl. Toxicol., 23, 478, 1994.
    • (1994) Fundam. Appl. Toxicol , vol.23 , pp. 478
    • Faustman, E.M.1    Allen, B.C.2    Kavlock, R.J.3    Kimmel, C.A.4
  • 47
    • 0015316975 scopus 로고
    • Effects of sodium arsenite on fetal development
    • Hood, R.D., Effects of sodium arsenite on fetal development, Bull. Environ. Contam. Toxicol., 7, 216, 1972.
    • (1972) Bull. Environ. Contam. Toxicol , vol.7 , pp. 216
    • Hood, R.D.1
  • 49
    • 0034029215 scopus 로고    scopus 로고
    • Evaluation of the prenatal developmental toxicity of orally administered arsenic trioxide in rats
    • Holson, J.F., Stump, D.G., Clevidence, K.J., Knapp, J.F., and Farr, C.H., Evaluation of the prenatal developmental toxicity of orally administered arsenic trioxide in rats, Food Chem. Toxicol., 38, 459, 2000.
    • (2000) Food Chem. Toxicol , vol.38 , pp. 459
    • Holson, J.F.1    Stump, D.G.2    Clevidence, K.J.3    Knapp, J.F.4    Farr, C.H.5
  • 50
    • 0033504650 scopus 로고    scopus 로고
    • Comparative effects of single intraperitoneal or oral doses of sodium arsenate or arsenic trioxide during in utero development
    • Stump, D.G., Holson, J.F., Fleeman, T.L., Nemec, M.D., and Farr, C.H., Comparative effects of single intraperitoneal or oral doses of sodium arsenate or arsenic trioxide during in utero development, Teratology, 60, 283, 1999.
    • (1999) Teratology , vol.60 , pp. 283
    • Stump, D.G.1    Holson, J.F.2    Fleeman, T.L.3    Nemec, M.D.4    Farr, C.H.5
  • 52
    • 0018052913 scopus 로고
    • Statistical analysis of teratologic data: Problems and advancements
    • Nelson, C.J. and Holson, J.F., Statistical analysis of teratologic data: problems and advancements, J. Environ. Pathol. Toxicol., 2, 187, 1978.
    • (1978) J. Environ. Pathol. Toxicol , vol.2 , pp. 187
    • Nelson, C.J.1    Holson, J.F.2
  • 54
    • 0000080398 scopus 로고
    • New tables for multiple comparisons with a control
    • Dunnett, C.W., New tables for multiple comparisons with a control, Biometrics, 20, 482, 1964.
    • (1964) Biometrics , vol.20 , pp. 482
    • Dunnett, C.W.1
  • 55
    • 84943709252 scopus 로고
    • Use of ranks in one-criterion variance analysis
    • Kruskal, W.H. and Wallis, W.A., Use of ranks in one-criterion variance analysis, J. Am. Statistical Assoc., 47, 583, 1952.
    • (1952) J. Am. Statistical Assoc , vol.47 , pp. 583
    • Kruskal, W.H.1    Wallis, W.A.2
  • 56
    • 0017013318 scopus 로고
    • Reduced interlitter variability in rats resulting from a restricted mating period, and reassessment of the "litter effect"
    • Holson, J.F., Scott, W.J., Gaylor, D.W., and Wilson, J.G., Reduced interlitter variability in rats resulting from a restricted mating period, and reassessment of the "litter effect", Teratology, 14, 135, 1976.
    • (1976) Teratology , vol.14 , pp. 135
    • Holson, J.F.1    Scott, W.J.2    Gaylor, D.W.3    Wilson, J.G.4
  • 57
    • 77957188604 scopus 로고
    • Developmental toxicity of 2,4,5-trichlorophenoxyacetic acid (2,4,5-T). I. Multireplicated dose-response studies in four inbred strains and one outbred stock of mice
    • Holson, J.F., Gaines, T.B., Nelson, C.J., LaBorde, J.B., Gaylor, D.W., Sheehan, D.M., and Young, J.F., Developmental toxicity of 2,4,5-trichlorophenoxyacetic acid (2,4,5-T). I. Multireplicated dose-response studies in four inbred strains and one outbred stock of mice, Fundam. Appl. Toxicol., 19, 286, 1992.
    • (1992) Fundam. Appl. Toxicol , vol.19 , pp. 286
    • Holson, J.F.1    Gaines, T.B.2    Nelson, C.J.3    LaBorde, J.B.4    Gaylor, D.W.5    Sheehan, D.M.6    Young, J.F.7
  • 59
    • 0030887391 scopus 로고    scopus 로고
    • Reproductive assessment by continuous breeding: Evolving study design and summaries of ninety studies
    • Chapin, R.E. and Sloane, R.A., Reproductive assessment by continuous breeding: evolving study design and summaries of ninety studies, Environ. Health Persp., 105(Suppl. 1), 199, 1997.
    • (1997) Environ. Health Persp , vol.105 , pp. 199
    • Chapin, R.E.1    Sloane, R.A.2
  • 61
    • 0037401126 scopus 로고    scopus 로고
    • Proposal for a tiered approach to developmental toxicity testing for veterinary pharmaceutical products for food-producing animals
    • Hurtt, M.E., Cappon, G.D., and Browning, A., Proposal for a tiered approach to developmental toxicity testing for veterinary pharmaceutical products for food-producing animals, Food Chem. Toxicol., 41, 611, 2003.
    • (2003) Food Chem. Toxicol , vol.41 , pp. 611
    • Hurtt, M.E.1    Cappon, G.D.2    Browning, A.3
  • 62
    • 85123816056 scopus 로고    scopus 로고
    • Finding of developmental toxicity studies of HBOC-201 in rodent and canine models [abstract]
    • Stump, D.G., Holson, J.F., Pearce, L.B., Rentko, V.T., and Gawryl, M.S., Finding of developmental toxicity studies of HBOC-201 in rodent and canine models [abstract], Birth Defects Res. (Part B), 68, 250, 2003.
    • (2003) Birth Defects Res. (Part B) , vol.68 , pp. 250
    • Stump, D.G.1    Holson, J.F.2    Pearce, L.B.3    Rentko, V.T.4    Gawryl, M.S.5
  • 63
    • 85123816602 scopus 로고    scopus 로고
    • A probable false positive finding of prenatal toxicity in the rodent model with a high molecular weight protein oxygen therapeutic: Evidence and implications [abstract]
    • Holson, J.F., Pearce, L.B., and Stump, D.G., A probable false positive finding of prenatal toxicity in the rodent model with a high molecular weight protein oxygen therapeutic: evidence and implications [abstract], Birth Defects Res. (Part B), 68, 249, 2003.
    • (2003) Birth Defects Res. (Part B) , vol.68 , pp. 249
    • Holson, J.F.1    Pearce, L.B.2    Stump, D.G.3
  • 64
    • 0017058778 scopus 로고
    • The multifactorial/threshold concept - use and misuses
    • Fraser, F.C., The multifactorial/threshold concept - use and misuses, Teratology, 14, 267, 1976.
    • (1976) Teratology , vol.14 , pp. 267
    • Fraser, F.C.1
  • 65
    • 0006355811 scopus 로고
    • Ontogeny of physiological regulations in the rat
    • Adolph, E.F., Ontogeny of physiological regulations in the rat, Quart. Rev. Biol., 32, 89, 1957.
    • (1957) Quart. Rev. Biol , vol.32 , pp. 89
    • Adolph, E.F.1
  • 66
    • 0026569461 scopus 로고
    • Mechanisms by which the pregnant ewe can sustain increased salt and water supply to the fetus
    • Gibson, K.J. and Lumbers, E.R., Mechanisms by which the pregnant ewe can sustain increased salt and water supply to the fetus, J. Physiol., 445, 569, 1992.
    • (1992) J. Physiol , vol.445 , pp. 569
    • Gibson, K.J.1    Lumbers, E.R.2
  • 67
    • 0027859087 scopus 로고
    • The roles of arginine vasopressin in fetal sodium balance and as a mediator of the effects of fetal "stress,"
    • Gibson, K.J. and Lumbers, E.R., The roles of arginine vasopressin in fetal sodium balance and as a mediator of the effects of fetal "stress," J. Develop. Physiol., 19, 125, 1993.
    • (1993) J. Develop. Physiol , vol.19 , pp. 125
    • Gibson, K.J.1    Lumbers, E.R.2
  • 68
    • 0000474463 scopus 로고
    • Modulation of embryo sensitivity to teratogen by nonspecific intrauterine immunopotentiation
    • Torchinsky, A., Fein, A., and Toder, V., Modulation of embryo sensitivity to teratogen by nonspecific intrauterine immunopotentiation, Toxicol. Methods, 5, 131, 1995.
    • (1995) Toxicol. Methods , vol.5 , pp. 131
    • Torchinsky, A.1    Fein, A.2    Toder, V.3
  • 69
    • 0016845318 scopus 로고
    • Reduction of drug-induced cleft palate in mice
    • Szabo, K.T. and Brent, R.L., Reduction of drug-induced cleft palate in mice, Lancet, 1, 1296, 1975.
    • (1975) Lancet , vol.1 , pp. 1296
    • Szabo, K.T.1    Brent, R.L.2
  • 70
    • 0017641613 scopus 로고
    • Cleft palate following prenatal food restriction in mice: Association with elevated maternal corticosteroids
    • Hemm, R.D., Arslanoglou, L., and Pollock, J.J., Cleft palate following prenatal food restriction in mice: association with elevated maternal corticosteroids, Teratology, 15, 243, 1977.
    • (1977) Teratology , vol.15 , pp. 243
    • Hemm, R.D.1    Arslanoglou, L.2    Pollock, J.J.3
  • 71
    • 0019123795 scopus 로고
    • In-vivo and in-vitro studies on the effects of maternal fasting during embryonic organ-ogenesis in the rat
    • Ellington, S., In-vivo and in-vitro studies on the effects of maternal fasting during embryonic organ-ogenesis in the rat, J. Repro. Fertil., 60, 383, 1980.
    • (1980) J. Repro. Fertil , vol.60 , pp. 383
    • Ellington, S.1
  • 72
    • 77950056784 scopus 로고
    • Effects of food restriction on the fetal development during major organogenesis in rats
    • Ikemi, N., Imada, J., Goto, T., Shimazu, H., and Yasuda, M., Effects of food restriction on the fetal development during major organogenesis in rats, Cong. Anom., 33, 363, 1993.
    • (1993) Cong. Anom , vol.33 , pp. 363
    • Ikemi, N.1    Imada, J.2    Goto, T.3    Shimazu, H.4    Yasuda, M.5
  • 73
    • 0027425570 scopus 로고
    • Food restriction during organogen-esis in rabbits: Effects on reproduction and the offspring
    • Petrere, J.A., Rohn, W.R., Grantham II, L.E., and Anderson, J.A., Food restriction during organogen-esis in rabbits: effects on reproduction and the offspring, Fundam. Appl. Toxicol., 21, 517, 1993.
    • (1993) Fundam. Appl. Toxicol , vol.21 , pp. 517
    • Petrere, J.A.1    Rohn, W.R.2    Grantham, IIL.E.3    Anderson, J.A.4
  • 74
    • 0019783829 scopus 로고
    • Dietary deprivation induces fetal loss and abortions in rabbits
    • Matsuzawa, T., Nakata, M., Goto, I., and Tsushima, M., Dietary deprivation induces fetal loss and abortions in rabbits, Toxicology, 22, 255, 1981.
    • (1981) Toxicology , vol.22 , pp. 255
    • Matsuzawa, T.1    Nakata, M.2    Goto, I.3    Tsushima, M.4
  • 76
    • 0030596466 scopus 로고    scopus 로고
    • Evidence that mammalian sex ratios at birth are partially controlled by parental hormone levels at the time of conception
    • James, W.H., Evidence that mammalian sex ratios at birth are partially controlled by parental hormone levels at the time of conception, J. Theor. Biol., 180, 271, 1996.
    • (1996) J. Theor. Biol , vol.180 , pp. 271
    • James, W.H.1
  • 77
    • 0033853673 scopus 로고    scopus 로고
    • Exposure to chemicals, offspring sex ratios, and their relevance to teratology [letter]
    • James, W.H., Exposure to chemicals, offspring sex ratios, and their relevance to teratology [letter], Teratology, 62, 75, 2000.
    • (2000) Teratology , vol.62 , pp. 75
    • James, W.H.1
  • 78
    • 0036840396 scopus 로고    scopus 로고
    • Comparative study of sodium valproate-induced skeletal malformations using single or double staining methods
    • Menegola, E., Broccia, M.L., Di Renzo, F., and Giavini, E., Comparative study of sodium valproate-induced skeletal malformations using single or double staining methods, Reprod. Toxicol., 16, 815, 2002.
    • (2002) Reprod. Toxicol , vol.16 , pp. 815
    • Menegola, E.1    Broccia, M.L.2    di Renzo, F.3    Giavini, E.4
  • 79
    • 0022900686 scopus 로고
    • Relationship between ossification and body weight of the CD-1 mouse fetus exposed in utero to anticonvulsant drugs
    • Sucheston, M.E., Hayes, T.G., and Eluma, F.O., Relationship between ossification and body weight of the CD-1 mouse fetus exposed in utero to anticonvulsant drugs, Terat. Carcinog. Mutagen, 6, 537, 1986.
    • (1986) Terat. Carcinog. Mutagen , vol.6 , pp. 537
    • Sucheston, M.E.1    Hayes, T.G.2    Eluma, F.O.3
  • 81
    • 0002990833 scopus 로고
    • Embryological considerations in teratology
    • Wilson, J.G. and Warkany, J., Eds., The University of Chicago Press, Chicago
    • Wilson, J.G., Embryological considerations in teratology. In Teratology: Principles and Techniques; Wilson, J.G. and Warkany, J., Eds., The University of Chicago Press, Chicago, 1965, p. 251.
    • (1965) Teratology: Principles and Techniques , pp. 251
    • Wilson, J.G.1
  • 82
    • 0021637726 scopus 로고
    • Fresh visceral examination of rat and rabbit fetuses used in teratogenicity testing
    • Stuckhardt, J.L. and Poppe, S.M., Fresh visceral examination of rat and rabbit fetuses used in teratogenicity testing, Terat., Carcin. Mutagen., 4, 181, 1984.
    • (1984) Terat., Carcin. Mutagen , vol.4 , pp. 181
    • Stuckhardt, J.L.1    Poppe, S.M.2
  • 83
    • 0003064131 scopus 로고
    • Detection of visceral alterations in mammalian species [abstract]
    • Staples, R.E., Detection of visceral alterations in mammalian species [abstract], Teratology, 9, 37, 1974.
    • (1974) Teratology , vol.9 , pp. 37
    • Staples, R.E.1
  • 84
    • 0014485109 scopus 로고
    • A rapid method for detecting malformations in rat fetuses
    • Barrow, M.V. and Taylor, W.J., A rapid method for detecting malformations in rat fetuses, J. Morphol., 127, 291, 1969.
    • (1969) J. Morphol , vol.127 , pp. 291
    • Barrow, M.V.1    Taylor, W.J.2
  • 85
    • 33846052958 scopus 로고
    • Morphogenetic studies of the rabbit. X. Racial variations in the gall bladder
    • Sawin, P. and Crary, D., Morphogenetic studies of the rabbit. X. Racial variations in the gall bladder, Anat. Rec., 110, 573, 1951.
    • (1951) Anat. Rec , vol.110 , pp. 573
    • Sawin, P.1    Crary, D.2
  • 86
    • 85052991849 scopus 로고    scopus 로고
    • An x-ray study of the incidence of supernumary ribs and presacral vertebrae in adults rats, mice and rabbits
    • Pitt, J.A., Snyder, L.T., Smith, B.L., Varsho, B.J., Nemec, M.D., and Holson, J.F., An x-ray study of the incidence of supernumary ribs and presacral vertebrae in adults rats, mice and rabbits, Teratology, 65, 328, 2002.
    • (2002) Teratology , vol.65 , pp. 328
    • Pitt, J.A.1    Snyder, L.T.2    Smith, B.L.3    Varsho, B.J.4    Nemec, M.D.5    Holson, J.F.6
  • 87
    • 77957187773 scopus 로고
    • Significance of supernumerary ribs in rodent developmental toxicity studies: Postnatal persistence in rats and mice
    • Chernoff, N., Rogers, J.M., Turner, C.I., and Francis, B.M., Significance of supernumerary ribs in rodent developmental toxicity studies: postnatal persistence in rats and mice, Fundam. Appl. Toxicol., 17, 448, 1991.
    • (1991) Fundam. Appl. Toxicol , vol.17 , pp. 448
    • Chernoff, N.1    Rogers, J.M.2    Turner, C.I.3    Francis, B.M.4
  • 89
    • 0023832962 scopus 로고
    • The post-natal fate of supernumerary ribs in rat teratogenicity studies
    • Wickramaratne, G.A. de S., The post-natal fate of supernumerary ribs in rat teratogenicity studies, J. Appl. Toxicol., 8, 91, 1988.
    • (1988) J. Appl. Toxicol , vol.8 , pp. 91
    • de Wickramaratne, G.A.S.1
  • 90
    • 0034105881 scopus 로고    scopus 로고
    • Postnatal evolution of supernumerary ribs in rats after a single administration of sodium salicylate
    • Foulon, O., Jaussely, C., Repetto, M., Urtizberea, M., and Blacker, A.M., Postnatal evolution of supernumerary ribs in rats after a single administration of sodium salicylate, J. Appl. Toxicol., 20, 205, 2000.
    • (2000) J. Appl. Toxicol , vol.20 , pp. 205
    • Foulon, O.1    Jaussely, C.2    Repetto, M.3    Urtizberea, M.4    Blacker, A.M.5
  • 91
    • 85027472202 scopus 로고
    • The inheritance of a rib variation in the rabbit
    • Green, E.L., The inheritance of a rib variation in the rabbit, Anat. Rec., 74, 47, 1939.
    • (1939) Anat. Rec , vol.74 , pp. 47
    • Green, E.L.1
  • 93
    • 0021052144 scopus 로고
    • Assessment of adult skeletons to detect prenatal exposure to trypan blue in mice
    • Beck, S.L., Assessment of adult skeletons to detect prenatal exposure to trypan blue in mice, Teratology, 28, 271, 1983.
    • (1983) Teratology , vol.28 , pp. 271
    • Beck, S.L.1
  • 96
    • 0033945292 scopus 로고    scopus 로고
    • Appropriate use of animal models in the assessment of risk during prenatal development: An illustration using inorganic arsenic
    • Holson, J.F., DeSesso, J., Jacobson, C., and Farr, C., Appropriate use of animal models in the assessment of risk during prenatal development: an illustration using inorganic arsenic, Teratology, 62, 51, 2000.
    • (2000) Teratology , vol.62 , pp. 51
    • Holson, J.F.1    DeSesso, J.2    Jacobson, C.3    Farr, C.4
  • 98
    • 0029037938 scopus 로고
    • A collaborative study in Japan on optimal treatment period and parameters for detection of male fertility disorders induced by drugs in rats
    • Takayama, S., Akaike, M., Kawashima, K., Takahashi, M., and Kurokawa, Y., A collaborative study in Japan on optimal treatment period and parameters for detection of male fertility disorders induced by drugs in rats, J. Am. Coll. Toxicol., 14, 266, 1995.
    • (1995) J. Am. Coll. Toxicol , vol.14 , pp. 266
    • Takayama, S.1    Akaike, M.2    Kawashima, K.3    Takahashi, M.4    Kurokawa, Y.5
  • 99
    • 0031848564 scopus 로고    scopus 로고
    • Endocrine active compounds: From biology to dose response assessment
    • Barton, H.A. and Andersen, M.E., Endocrine active compounds: from biology to dose response assessment, Crit. Rev. Toxicol., 28, 363, 1998.
    • (1998) Crit. Rev. Toxicol , vol.28 , pp. 363
    • Barton, H.A.1    Andersen, M.E.2
  • 100
    • 84930902864 scopus 로고    scopus 로고
    • Perchlorate literature review and summary: Developmental effects, metabolism, receptor kinetics and pharmacological uses
    • Sterner, T.R. and Mattie D.R., Perchlorate literature review and summary: developmental effects, metabolism, receptor kinetics and pharmacological uses, NTIS Technical Report (NTIS/ADA367421), 1998.
    • (1998) NTIS Technical Report (NTIS/ADA367421)
    • Sterner, T.R.1    Mattie, D.R.2
  • 101
    • 0035700809 scopus 로고    scopus 로고
    • Overview of studies on rat sperm motion analysis using a Hamilton-Thorne Sperm Analyzer - collaborative working study
    • Kato, M., Fukunishi, K., Ikegawa, S., Higuchi, H., Sato, M., Horimoto, M., and Ito, S., Overview of studies on rat sperm motion analysis using a Hamilton-Thorne Sperm Analyzer - collaborative working study, J. Toxicol. Sci., 26, 285, 2001.
    • (2001) J. Toxicol. Sci , vol.26 , pp. 285
    • Kato, M.1    Fukunishi, K.2    Ikegawa, S.3    Higuchi, H.4    Sato, M.5    Horimoto, M.6    Ito, S.7
  • 102
    • 0027032045 scopus 로고
    • Endpoints of spermatotoxicity in the rat after short duration exposures to fourteen reproductive toxicants
    • Linder, R.E., Strader, L.F., Slott, V.L., and Suarez, J.D., Endpoints of spermatotoxicity in the rat after short duration exposures to fourteen reproductive toxicants, Repro. Toxicol., 6, 491, 1992.
    • (1992) Repro. Toxicol , vol.6 , pp. 491
    • Linder, R.E.1    Strader, L.F.2    Slott, V.L.3    Suarez, J.D.4
  • 103
    • 0034071059 scopus 로고    scopus 로고
    • Evaluation of a Tier I screening battery for detecting endocrine-active compounds (EACs) using the positive controls testosterone, coumestrol, progesterone, and RU486
    • O'Connor, J.C., Davis, L.G., Frame, S.R., and Cook, J.C., Evaluation of a Tier I screening battery for detecting endocrine-active compounds (EACs) using the positive controls testosterone, coumestrol, progesterone, and RU486, Toxicol. Sci., 54, 338, 2000.
    • (2000) Toxicol. Sci , vol.54 , pp. 338
    • O'Connor, J.C.1    Davis, L.G.2    Frame, S.R.3    Cook, J.C.4
  • 105
    • 0000244534 scopus 로고
    • The oestrous cycle in the rat and its associated phenomena
    • Long, J.A. and Evans, H.M., The oestrous cycle in the rat and its associated phenomena, Mem. Univ. Calif., 6, 1, 1922.
    • (1922) Mem. Univ. Calif , vol.6 , pp. 1
    • Long, J.A.1    Evans, H.M.2
  • 108
    • 0025933190 scopus 로고
    • Reproductive and developmental toxicity studies with amlodipine in rats and rabbits
    • Horimoto, M., Takeuchi, K., Iijima, M., and Tachibana, M., Reproductive and developmental toxicity studies with amlodipine in rats and rabbits, Oyo Yakuri, 42, 167, 1991.
    • (1991) Oyo Yakuri , vol.42 , pp. 167
    • Horimoto, M.1    Takeuchi, K.2    Iijima, M.3    Tachibana, M.4
  • 109
    • 34250963730 scopus 로고
    • Ultraschallante bei jungen Mausen [Ultrasounds in young mice]
    • Zippelius, H.M. and Schleidt, W.M., Ultraschallante bei jungen Mausen [Ultrasounds in young mice], Naturwissenschaften, 43, 502, 1956.
    • (1956) Naturwissenschaften , vol.43 , pp. 502
    • Zippelius, H.M.1    Schleidt, W.M.2
  • 110
    • 0041747381 scopus 로고
    • Sound analysis of ultrasonic distress calls of mouse pups as a function of their age
    • Noirot, E. and Pye, D., Sound analysis of ultrasonic distress calls of mouse pups as a function of their age, Animal Behavior, 17, 340, 1969.
    • (1969) Animal Behavior , vol.17 , pp. 340
    • Noirot, E.1    Pye, D.2
  • 111
    • 0019743263 scopus 로고
    • The foetoplacental unit and the initiation of lactation in the rat
    • Nicholas, K.R. and Hartmann, P.E., The foetoplacental unit and the initiation of lactation in the rat, Aust. J. Biol. Sci., 34, 455, 1981.
    • (1981) Aust. J. Biol. Sci , vol.34 , pp. 455
    • Nicholas, K.R.1    Hartmann, P.E.2
  • 112
    • 0343693469 scopus 로고
    • Spontaneous ejaculation in rat
    • Orbach, J., Spontaneous ejaculation in rat, Science, 134, 1072, 1961.
    • (1961) Science , vol.134 , pp. 1072
    • Orbach, J.1
  • 113
    • 0014031011 scopus 로고
    • Diurnal variation in the spontaneous ejaculations of the male albino rat
    • Kihlström, J.E., Diurnal variation in the spontaneous ejaculations of the male albino rat, Nature, 209, 513, 1966.
    • (1966) Nature , vol.209 , pp. 513
    • Kihlström, J.E.1
  • 114
    • 0016724439 scopus 로고
    • Variables affecting "spontaneous" seminal emission in rats
    • Beach, F.A., Variables affecting "spontaneous" seminal emission in rats, Physiol. Behav., 15(1), 91, 1975.
    • (1975) Physiol. Behav , vol.15 , Issue.1 , pp. 91
    • Beach, F.A.1
  • 115
    • 0014115796 scopus 로고
    • Spontaneous seminal ejaculation and genital grooming in rats
    • Orbach, J., Miller, M., Billimoria, A., and Solhkhah, N., Spontaneous seminal ejaculation and genital grooming in rats, Brain Res., 5, 520, 1967.
    • (1967) Brain Res , vol.5 , pp. 520
    • Orbach, J.1    Miller, M.2    Billimoria, A.3    Solhkhah, N.4
  • 116
    • 0345411501 scopus 로고    scopus 로고
    • Interpreting the toxicologic significance of alterations in anogenital distance: Potential for confounding effects of progeny body weights
    • Gallavan, Jr., R.H., Holson, J.F., Stump, D.G., Knapp, J.F., and Reynolds, V.L., Interpreting the toxicologic significance of alterations in anogenital distance: potential for confounding effects of progeny body weights, Repro. Toxicol., 13, 383, 1999.
    • (1999) Repro. Toxicol , vol.13 , pp. 383
    • Gallavan, R.H.1    Holson, J.F.2    Stump, D.G.3    Knapp, J.F.4    Reynolds, V.L.5
  • 117
    • 0002114225 scopus 로고    scopus 로고
    • Endpoints of reproductive system development
    • Daston, G. and Kimmel, C.A., Eds., International Life Sciences Institute, Washington, DC
    • Clark, R.L., Endpoints of reproductive system development, in An Evaluation and Interpretation of Reproductive Endpoints for Human Health Risk Assessment, Daston, G. and Kimmel, C.A., Eds., International Life Sciences Institute, Washington, DC, 1998, p. 10.
    • (1998) An Evaluation and Interpretation of Reproductive Endpoints for Human Health Risk Assessment , pp. 10
    • Clark, R.L.1
  • 118
    • 0033967188 scopus 로고    scopus 로고
    • The peripubertal male rat assay as an alternative to the Hershberger castrated male rat assay for the detection of anti-androgens, oestrogens and metabolic modulators
    • Ashby, J. and Lefevre, P.A., The peripubertal male rat assay as an alternative to the Hershberger castrated male rat assay for the detection of anti-androgens, oestrogens and metabolic modulators, J. Appl. Toxicol., 20, 35, 2000.
    • (2000) J. Appl. Toxicol , vol.20 , pp. 35
    • Ashby, J.1    Lefevre, P.A.2
  • 120
    • 0036852284 scopus 로고    scopus 로고
    • Sex ratios of Russian pesticide producers exposed to dioxin
    • Ryan, J.J., Amirova, Z., and Carrier, G., Sex ratios of Russian pesticide producers exposed to dioxin, Environ. Health Persp., 110, A 699, 2002.
    • (2002) Environ. Health Persp , vol.110 , pp. A699
    • Ryan, J.J.1    Amirova, Z.2    Carrier, G.3
  • 122
    • 85123814642 scopus 로고
    • Tripartite Guideline on Detection of Toxicity to Reproduction for Medicinal Products
    • Section 4.1.2, September 22
    • International Conference on Harmonisation (ICH), Tripartite Guideline on Detection of Toxicity to Reproduction for Medicinal Products, Fed. Regist., Section 4.1.2, September 22, 1994.
    • (1994) Fed. Regist
  • 125
    • 0030669383 scopus 로고    scopus 로고
    • Differential follicle counts as a screen for chemically-induced ovarian toxicity in mice: Results from continuous breeding bioassays
    • Bolon, B., Bucci, J.J., Warbritton, A.R., Chen, J.J., Mattison, P.R., and Heindel, J.J., Differential follicle counts as a screen for chemically-induced ovarian toxicity in mice: results from continuous breeding bioassays, Fundam. Appl. Toxicol., 39, 1, 1997.
    • (1997) Fundam. Appl. Toxicol , vol.39 , pp. 1
    • Bolon, B.1    Bucci, J.J.2    Warbritton, A.R.3    Chen, J.J.4    Mattison, P.R.5    Heindel, J.J.6
  • 126
    • 0031563526 scopus 로고    scopus 로고
    • Influence of sampling on the reproducibility of ovarian follicle counts in mouse toxicity studies
    • Bucci, T.J., Bolon, B., Warbritton, A.R., Chen, J.J., and Heindel, J.J., Influence of sampling on the reproducibility of ovarian follicle counts in mouse toxicity studies, Reprod. Toxicol., 11, 689, 1997.
    • (1997) Reprod. Toxicol , vol.11 , pp. 689
    • Bucci, T.J.1    Bolon, B.2    Warbritton, A.R.3    Chen, J.J.4    Heindel, J.J.5
  • 127
    • 85123815773 scopus 로고    scopus 로고
    • Interpretation of low-incidence findings in developmental and reproductive toxicity studies, presented at the
    • Washington, DC
    • Holson, J.F., Interpretation of low-incidence findings in developmental and reproductive toxicity studies, presented at the 2002 Annual Winter Meeting of the Toxicology Forum, Washington, DC, 2002.
    • (2002) 2002 Annual Winter Meeting of the Toxicology Forum
    • Holson, J.F.1
  • 130
    • 0022416407 scopus 로고
    • Extrapolation of the evidence on teratogenicity of chemicals between humans and experimental animals: Chemicals other than drugs
    • Hemminki, K. and Vineis, P., Extrapolation of the evidence on teratogenicity of chemicals between humans and experimental animals: chemicals other than drugs, Teratog. Carcinog. Mutagen., 5, 251, 1985.
    • (1985) Teratog. Carcinog. Mutagen , vol.5 , pp. 251
    • Hemminki, K.1    Vineis, P.2
  • 131
    • 85123815988 scopus 로고
    • Eds., Proceedings of the Workshop on the Qualitative and Quantitative Comparability of Human and Animal Developmental Neurotoxicity
    • Kimmel, C.A., Rees, D.C., and Francis, E.Z., Eds., Proceedings of the Workshop on the Qualitative and Quantitative Comparability of Human and Animal Developmental Neurotoxicity, Neurotoxicol. Teratol, 12, 173, 1990.
    • (1990) Neurotoxicol. Teratol , vol.12 , pp. 173
    • Kimmel, C.A.1    Rees, D.C.2    Francis, E.Z.3
  • 132
    • 0027635817 scopus 로고
    • Assessment of the effectiveness of animal developmental toxicity testing for human safety
    • Newman, L.M., Johnson, E.M., and Staples, R.E., Assessment of the effectiveness of animal developmental toxicity testing for human safety, Reprod. Toxicol., 7, 359, 1993.
    • (1993) Reprod. Toxicol , vol.7 , pp. 359
    • Newman, L.M.1    Johnson, E.M.2    Staples, R.E.3
  • 134
    • 0018425188 scopus 로고
    • Reproduction toxicological studies on cefazedone
    • Frohberg, H., Gleich, J., and Unkelbach, H.D., Reproduction toxicological studies on cefazedone, Arzneim. Forsch., 29, 419, 1979.
    • (1979) Arzneim. Forsch , vol.29 , pp. 419
    • Frohberg, H.1    Gleich, J.2    Unkelbach, H.D.3
  • 135
    • 85123816800 scopus 로고    scopus 로고
    • Cardiac abnormalities induced by zinc deficiency are associated with alterations in the expression of genes regulated by zinc-finger transcription factors
    • Duffy, J.Y., Overmann, G.J., Keen, C.L., and Daston, G.P., Cardiac abnormalities induced by zinc deficiency are associated with alterations in the expression of genes regulated by zinc-finger transcription factors, Teratology, 59, 382, 1999.
    • (1999) Teratology , vol.59 , pp. 382
    • Duffy, J.Y.1    Overmann, G.J.2    Keen, C.L.3    Daston, G.P.4
  • 141
    • 0028299078 scopus 로고
    • Developmental phase alters dosimetry-teratogenicity relationship for 2-methoxyethanol in CD-1 Mice
    • Terry, K.K., Elswick, B.A., Stedman, D.B., and Welsch, F., Developmental phase alters dosimetry-teratogenicity relationship for 2-methoxyethanol in CD-1 Mice, Teratology, 49, 218, 1994.
    • (1994) Teratology , vol.49 , pp. 218
    • Terry, K.K.1    Elswick, B.A.2    Stedman, D.B.3    Welsch, F.4
  • 142
    • 0027267685 scopus 로고
    • Pharmacokinetics of 2-methoxyethanol and 2-methoxyacetic acid in the pregnant mouse: A physiologically based mathematical model
    • Clarke, D.O., Elswick, B.A., Welsch, F., and Conolly, R.R., Pharmacokinetics of 2-methoxyethanol and 2-methoxyacetic acid in the pregnant mouse: a physiologically based mathematical model, Toxicol. Appl. Pharm., 121, 239, 1993.
    • (1993) Toxicol. Appl. Pharm , vol.121 , pp. 239
    • Clarke, D.O.1    Elswick, B.A.2    Welsch, F.3    Conolly, R.R.4
  • 143
    • 0034757851 scopus 로고    scopus 로고
    • Teratogenicity of isotretinoin revisited: Species variation and the role of all-trans-retinoic acid
    • Nau, H., Teratogenicity of isotretinoin revisited: species variation and the role of all-trans-retinoic acid, J. Am. Acad. Dermatol., 45, S183, 2001.
    • (2001) J. Am. Acad. Dermatol , vol.45 , pp. S183
    • Nau, H.1
  • 144
    • 0030890853 scopus 로고    scopus 로고
    • The area under the concentration-time curve of all-trans-retinoic acid is the most suitable pharmacokinetic correlate to the embryotoxicity of this retinoid in the rat
    • Tzimas, G., Thiel, R., Chahoud, I., and Nau, H., The area under the concentration-time curve of all-trans-retinoic acid is the most suitable pharmacokinetic correlate to the embryotoxicity of this retinoid in the rat, Toxicol. Appl. Pharm., 143, 436, 1997.
    • (1997) Toxicol. Appl. Pharm , vol.143 , pp. 436
    • Tzimas, G.1    Thiel, R.2    Chahoud, I.3    Nau, H.4
  • 145
    • 0028108856 scopus 로고
    • Comparative teratology and transplacental pharmacokinetics of all-trans-retinoic acid, 13-cis-retinoic acid, and retinyl palmitate following daily administration in rats
    • Collins, M.D., Tzimas, G., Hummler, H., Bürgin, H., and Nau, H., Comparative teratology and transplacental pharmacokinetics of all-trans-retinoic acid, 13-cis-retinoic acid, and retinyl palmitate following daily administration in rats, Toxicol. Appl. Pharm., 127, 132, 1994.
    • (1994) Toxicol. Appl. Pharm , vol.127 , pp. 132
    • Collins, M.D.1    Tzimas, G.2    Hummler, H.3    Bürgin, H.4    Nau, H.5
  • 146
    • 0027722159 scopus 로고
    • Embryotoxicity and teratogenicity of topical retinoic acid
    • Nau, H., Embryotoxicity and teratogenicity of topical retinoic acid, Skin Pharmacol., 6(Suppl.1), 35, 1993.
    • (1993) Skin Pharmacol , vol.6 , pp. 35
    • Nau, H.1
  • 147
    • 85123814805 scopus 로고
    • Health Effects Division, Office of Pesticides Programs, Washington, DC
    • U.S. Environmental Protection Agency, Standard Evaluation Procedure, Developmental Toxicity Studies, Health Effects Division, Office of Pesticides Programs, Washington, DC, 1993.
    • (1993) Standard Evaluation Procedure, Developmental Toxicity Studies
  • 148
    • 25844519544 scopus 로고
    • The effect of alcohol on the intelligent behavior of the white rat and its progeny
    • Arlitt, A.H., The effect of alcohol on the intelligent behavior of the white rat and its progeny, Psychol. Monogr., 26, 1, 1919.
    • (1919) Psychol. Monogr , vol.26 , pp. 1
    • Arlitt, A.H.1
  • 149
    • 0000842423 scopus 로고
    • Effect of 4-amino-pteroylglutamic acid (aminopterin) on early pregnancy
    • Thiersch, J.B. and Phillips, F.S., Effect of 4-amino-pteroylglutamic acid (aminopterin) on early pregnancy, Proc. Soc. Exp. Biol. Med., 74, 204, 1950.
    • (1950) Proc. Soc. Exp. Biol. Med , vol.74 , pp. 204
    • Thiersch, J.B.1    Phillips, F.S.2
  • 150
    • 84910191533 scopus 로고
    • Cigarette smoking in pregnant women
    • Shoeneck, F.J., Cigarette smoking in pregnant women, N.Y. State J. Med., 41, 1945, 1941.
    • (1941) N.Y. State J. Med , vol.41 , pp. 1945
    • Shoeneck, F.J.1
  • 151
    • 85027473786 scopus 로고
    • Experimental intersexuality. The effects of estrogens on the antenatal sexual development of the rat
    • Greene, R.R., Burrill, M.W., and Ivy, A.C., Experimental intersexuality. The effects of estrogens on the antenatal sexual development of the rat, Am. J. Anat., 67, 305, 1940.
    • (1940) Am. J. Anat , vol.67 , pp. 305
    • Greene, R.R.1    Burrill, M.W.2    Ivy, A.C.3
  • 152
    • 84900797269 scopus 로고
    • Comparative teratogenicity of morphine, heroin and methadone in the hamster
    • Geber, W.F. and Schramm, L.C., Comparative teratogenicity of morphine, heroin and methadone in the hamster, Pharmacologist, 11, 248, 1969.
    • (1969) Pharmacologist , vol.11 , pp. 248
    • Geber, W.F.1    Schramm, L.C.2
  • 153
    • 85123816936 scopus 로고
    • Russell, L.B, X-ray induced developmental abnormalities in the mouse and their use in the analysis of embryological patterns
    • Russell, L.B, X-ray induced developmental abnormalities in the mouse and their use in the analysis of embryological patterns, J. Exp. Zool., 114, 545, 1950.
    • (1950) J. Exp. Zool , vol.114 , pp. 545
  • 154
    • 0000185397 scopus 로고
    • Fetal Minamata disease: A neuropathological study of two cases of intrauterine intoxication by methyl mercury compound
    • Matsumoto, H., Koya, G., and Takeuchi, T., Fetal Minamata disease: A neuropathological study of two cases of intrauterine intoxication by methyl mercury compound, J. Neuropathol. Exp. Neurol., 24, 563, 1965.
    • (1965) J. Neuropathol. Exp. Neurol , vol.24 , pp. 563
    • Matsumoto, H.1    Koya, G.2    Takeuchi, T.3
  • 155
    • 0000339160 scopus 로고
    • Report on Yusno (chlorobiphenyls poisoning). Pregnant women and their fetuses
    • Taki, I., Hisanaga, S., and Amagase, Y., Report on Yusno (chlorobiphenyls poisoning). Pregnant women and their fetuses, Fukuoka Acta Med., 60, 471, 1969.
    • (1969) Fukuoka Acta Med , vol.60 , pp. 471
    • Taki, I.1    Hisanaga, S.2    Amagase, Y.3
  • 156
    • 84987169040 scopus 로고
    • The experimental production of pseudohermaphroditism in the monkey
    • van Wagenen, G. and Hamilton, J.B., The experimental production of pseudohermaphroditism in the monkey, Essays Biol., 583, 1943.
    • (1943) Essays Biol , vol.583
    • van Wagenen, G.1    Hamilton, J.B.2
  • 157
    • 0000962444 scopus 로고
    • Kindliche Missbildungen nach Medikament wahrend der Draviditat?
    • Lenz, W., Kindliche Missbildungen nach Medikament wahrend der Draviditat?, Dtsch. Med. Wochen-schr., 86, 2555, 1961.
    • (1961) Dtsch. Med. Wochen-schr , vol.86 , pp. 2555
    • Lenz, W.1
  • 158
    • 47349113508 scopus 로고
    • Thalidomide and congenital abnormalities
    • McBride, W.G., Thalidomide and congenital abnormalities, Lancet, 2, 1358, 1961.
    • (1961) Lancet , vol.2 , pp. 1358
    • McBride, W.G.1
  • 160
    • 0020525511 scopus 로고
    • The value of animal teratogenicity testing for predicting human risk
    • Brown, N.A. and Fabro, S.F., The value of animal teratogenicity testing for predicting human risk, Clin. Obstet. Gynecol., 26(2), 467, 1983.
    • (1983) Clin. Obstet. Gynecol , vol.26 , Issue.2 , pp. 467
    • Brown, N.A.1    Fabro, S.F.2
  • 161
    • 0025054704 scopus 로고
    • Workshop on the qualitative and quantitative comparability of human and animal developmental neurotoxicity: Testing methods in developmental neurotoxicity for use in human risk assessment
    • Buelke-Sam, J. and Mactutus, C., Workshop on the qualitative and quantitative comparability of human and animal developmental neurotoxicity: testing methods in developmental neurotoxicity for use in human risk assessment, Neurotoxicol. Teratol., 12, 269, 1990.
    • (1990) Neurotoxicol. Teratol , vol.12 , pp. 269
    • Buelke-Sam, J.1    Mactutus, C.2
  • 162
    • 0003759115 scopus 로고
    • 8th ed., The Johns Hopkins University Press, Baltimore
    • Shepard, T.H., Catalog of Teratogenic Agents, 8th ed., The Johns Hopkins University Press, Baltimore, 1995.
    • (1995) Catalog of Teratogenic Agents
    • Shepard, T.H.1
  • 165
    • 0003834145 scopus 로고
    • OTA-BA-266, U.S. Government Printing Office, Washington, DC
    • U.S. Congress, Office of Technology Assessment, Reproductive Health Hazards in the Workplace, OTA-BA-266, U.S. Government Printing Office, Washington, DC, 1985, p. 161.
    • (1985) Reproductive Health Hazards in the Workplace , pp. 161
  • 166
  • 167
    • 0003925997 scopus 로고
    • International Conference on Harmonisation; Guideline on detection of toxicity to reproduction for medicinal products
    • (No. 183)
    • U.S. Food and Drug Administration, International Conference on Harmonisation; Guideline on detection of toxicity to reproduction for medicinal products. Fed. Regist., 59(No. 183), 1994.
    • (1994) Fed. Regist , vol.59
  • 168
    • 47249107606 scopus 로고    scopus 로고
    • Guidelines for Testing of Chemicals
    • Section 4, No. 414: adopted 22 January
    • Organization for Economic Cooperation and Development, Guidelines for Testing of Chemicals. Section 4, No. 414: Teratogenicity, adopted 22 January 2001.
    • (2001) Teratogenicity
  • 169
    • 85123815421 scopus 로고    scopus 로고
    • Office of Food Additive Safety, IV.C.9.b., Guidelines for developmental toxicity studies
    • College Park, MD
    • U.S. Food and Drug Administration, Office of Food Additive Safety, IV.C.9.b., Guidelines for developmental toxicity studies, Redbook 2000-Toxicological Principles for the Safety Assessment of Food Ingredients, College Park, MD, 2000.
    • (2000) Redbook 2000-Toxicological Principles for the Safety Assessment of Food Ingredients
  • 172
    • 85123815545 scopus 로고    scopus 로고
    • Office of Food Additive Safety, IV.C.9.a., Guidelines for reproduction studies
    • College Park, MD
    • U.S. Food and Drug Administration, Office of Food Additive Safety, IV.C.9.a., Guidelines for reproduction studies, Redbook 2000-Toxicological Principles for the Safety Assessment of Food Ingredients, College Park, MD, 2000.
    • (2000) Redbook 2000-Toxicological Principles for the Safety Assessment of Food Ingredients
  • 174
    • 0037909184 scopus 로고    scopus 로고
    • Office of Prevention, Pesticides and Toxic Substances (OPPTS) 870.3800
    • U.S. Environmental Protection Agency, Health Effects Test Guidelines; Reproduction and Fertility Effects, Office of Prevention, Pesticides and Toxic Substances (OPPTS) 870.3800, 1998b.
    • (1998) Health Effects Test Guidelines; Reproduction and Fertility Effects


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