A two-generation reproductive toxicity study of octamethylcyclotetrasiloxane (D4) in rats exposed by whole-body vapor inhalation

Reproductive Toxicology

Volumn 23, Issue 2, 2007, Pages 202-215

  Siddiqui, Waheed H ^a   Stump, Donald G ^b   Plotzke, Kathleen P ^a   Holson, Joseph F ^b   Meeks, Robert G ^a  

^a DOW CORNING CORPORATION   (United States)

^b WIL RESEARCH LABORATORIES   (United States)

Author keywords

D4; Inhalation; Octamethylcyclotetrasiloxane; Rat; Reproductive toxicity; Silicone; Two generation

Indexed keywords

OCTAMETHYLCYCLOTETRASILOXANE; SILOXANE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ARTICLE; BIRTH; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ESTRUS CYCLE; EXPOSURE; FEMALE; FERTILITY; GESTATION PERIOD; LITTER SIZE; MALE; MATING; NEWBORN MORTALITY; NIDATION; NONHUMAN; OVULATION; PERINATAL DEVELOPMENT; PERINATAL PERIOD; PROGENY; RAT; REPRODUCTIVE TOXICITY; SENESCENCE; WEANING;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, INHALATION; ANIMALS; ANIMALS, NEWBORN; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO IMPLANTATION; ESTROUS CYCLE; FEMALE; FERTILITY; GENITALIA, MALE; INHALATION EXPOSURE; LITTER SIZE; LONGEVITY; MALE; NO-OBSERVED-ADVERSE-EFFECT LEVEL; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCTION; SILOXANES; SPERM MOTILITY; SPERMATOGENESIS; SPERMATOZOA;

ANIMALIA; RATTUS;

EID: 33846841028     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.reprotox.2006.11.011     Document Type: Article

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