메뉴 건너뛰기




Volumn 5, Issue 1, 2009, Pages 99-116

Role of atazanavir in the treatment of HIV infection

Author keywords

Atazanavir; Drug resistance; HIV; Protease inhibitors

Indexed keywords

AMIODARONE; ANTIARRHYTHMIC AGENT; ANTIBIOTIC AGENT; ANTICOAGULANT AGENT; ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; ANTIFUNGAL AGENT; ANTIHISTAMINIC AGENT; ASTEMIZOLE; ATAZANAVIR; BEPRIDIL; CARBAMAZEPINE; CLARITHROMYCIN; FOSAMPRENAVIR; IRINOTECAN; ITRACONAZOLE; KETOCONAZOLE; LAMOTRIGINE; LIDOCAINE; LOPINAVIR; PHENOBARBITAL; PHENYTOIN; PROTEINASE INHIBITOR; QUINIDINE; RIFABUTIN; RIFAMPICIN; RITONAVIR; TERFENADINE; UNINDEXED DRUG; WARFARIN;

EID: 67650553226     PISSN: 11766336     EISSN: 1178203X     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (21)

References (83)
  • 1
    • 77949482436 scopus 로고    scopus 로고
    • USA. Reyataz product information, Accessed 31 Aug 2008, Available from
    • Bristol Myers Squibb Company. Princeton, NJ 08543, USA. Reyataz product information. [Accessed 31 Aug 2008]. Available from: http://packageinserts.bms. com/pi/pi-reyataz.pdf
    • Princeton, NJ 08543
  • 2
    • 0037379517 scopus 로고    scopus 로고
    • Activities of atazanavir (BMS-232632) against a large panel of HIV type 1 clinical isolates resistant to one or more approved protease inhibitors
    • Colonno R, Thiry A, Limoli K, Parkin N. Activities of atazanavir (BMS-232632) against a large panel of HIV type 1 clinical isolates resistant to one or more approved protease inhibitors. Antimicrob Agents Chemother. 2003;47(4):1324-1333.
    • (2003) Antimicrob Agents Chemother , vol.47 , Issue.4 , pp. 1324-1333
    • Colonno, R.1    Thiry, A.2    Limoli, K.3    Parkin, N.4
  • 3
    • 0035313368 scopus 로고    scopus 로고
    • Hollow-fiber unit evaluation of a new HIV type 1 protease inhibitor, BMS-232632, for determination of the linked pharmacodynamic variable
    • Drusano G, Bilello J, Preston S, et al. Hollow-fiber unit evaluation of a new HIV type 1 protease inhibitor, BMS-232632, for determination of the linked pharmacodynamic variable. J Infect Dis. 2001;183(7):1126-1129.
    • (2001) J Infect Dis , vol.183 , Issue.7 , pp. 1126-1129
    • Drusano, G.1    Bilello, J.2    Preston, S.3
  • 4
    • 2442657656 scopus 로고    scopus 로고
    • Identifi cation of I50L as the signature atazanavir (ATV)-resistance mutation in treatment-naive HIV-1-infected patients receiving ATV-containing regimens
    • Colonno R, Rose R, McLaren C, Thiry A, Parkin N, Friborg J. Identifi cation of I50L as the signature atazanavir (ATV)-resistance mutation in treatment-naive HIV-1-infected patients receiving ATV-containing regimens. J Infect Dis. 2004;189(10):1802-1810.
    • (2004) J Infect Dis , vol.189 , Issue.10 , pp. 1802-1810
    • Colonno, R.1    Rose, R.2    McLaren, C.3    Thiry, A.4    Parkin, N.5    Friborg, J.6
  • 5
    • 3342924014 scopus 로고    scopus 로고
    • Comparison of once-daily atazanavir with efavirenz, each in combination with fixed-dose ZDV and lamivudine, as initial therapy for patients infected with HIV
    • Squires K, Lazzarin A, Gatell JM, et al. Comparison of once-daily atazanavir with efavirenz, each in combination with fixed-dose ZDV and lamivudine, as initial therapy for patients infected with HIV. J Acquir Immune Defic Syndr. 2004;36(5):1011-1019.
    • (2004) J Acquir Immune Defic Syndr , vol.36 , Issue.5 , pp. 1011-1019
    • Squires, K.1    Lazzarin, A.2    Gatell, J.M.3
  • 6
    • 46149111677 scopus 로고    scopus 로고
    • The HIV-1 protease resistance mutation I50L is associated with resistance to atazanavir and susceptibility to other protease inhibitors in multiple mutational contexts
    • Sista P, Wasikowski B, Lecocq P, Pattery T, Bacheler L. The HIV-1 protease resistance mutation I50L is associated with resistance to atazanavir and susceptibility to other protease inhibitors in multiple mutational contexts. J Clin Virol. 2008;42(4):405-408.
    • (2008) J Clin Virol , vol.42 , Issue.4 , pp. 405-408
    • Sista, P.1    Wasikowski, B.2    Lecocq, P.3    Pattery, T.4    Bacheler, L.5
  • 7
    • 34547927815 scopus 로고    scopus 로고
    • Changing rates and patterns of drug resistance mutations in antiretroviral-experienced HIV-infected patients
    • De Mendoza C, Garrido C, Corral A, et al. Changing rates and patterns of drug resistance mutations in antiretroviral-experienced HIV-infected patients. AIDS Res Hum Retroviruses. 2007;23(7):879-885.
    • (2007) AIDS Res Hum Retroviruses , vol.23 , Issue.7 , pp. 879-885
    • De Mendoza, C.1    Garrido, C.2    Corral, A.3
  • 8
    • 46349092759 scopus 로고    scopus 로고
    • Update of the drug resistance mutations in HIV-1: Spring 2008
    • Johnson V, Brun-Vezinet F, Clotet B, et al. Update of the drug resistance mutations in HIV-1: Spring 2008. Top HIV Med. 2008;16(1):62-68.
    • (2008) Top HIV Med , vol.16 , Issue.1 , pp. 62-68
    • Johnson, V.1    Brun-Vezinet, F.2    Clotet, B.3
  • 9
    • 7944228403 scopus 로고    scopus 로고
    • Predictors of virological response to atazanavir in protease inhibitor-experienced patients
    • Barrios A, Rendon AL, Gallego O, et al. Predictors of virological response to atazanavir in protease inhibitor-experienced patients. HIV Clin Trials. 2004;5(4):201-205.
    • (2004) HIV Clin Trials , vol.5 , Issue.4 , pp. 201-205
    • Barrios, A.1    Rendon, A.L.2    Gallego, O.3
  • 10
    • 34547749064 scopus 로고    scopus 로고
    • Virological failure and subsequent resistance profiles in individuals exposed to atazanavir
    • Stebbing J, Nathan B, Jones R, et al. Virological failure and subsequent resistance profiles in individuals exposed to atazanavir. AIDS. 2007;21(13):1826-1828.
    • (2007) AIDS , vol.21 , Issue.13 , pp. 1826-1828
    • Stebbing, J.1    Nathan, B.2    Jones, R.3
  • 11
    • 45949095398 scopus 로고    scopus 로고
    • Atazanavir in patients with persistent viral replication despite HAART: Results from the French prospective NADIS cohort
    • Cuzin L, Flandre P, Pugliese P, et al. Atazanavir in patients with persistent viral replication despite HAART: Results from the French prospective NADIS cohort. HIV Clin Trials. 2008;9(3):147-151.
    • (2008) HIV Clin Trials , vol.9 , Issue.3 , pp. 147-151
    • Cuzin, L.1    Flandre, P.2    Pugliese, P.3
  • 12
    • 48449083017 scopus 로고    scopus 로고
    • HIV-1 drug resistance mutations: An updated framework for the second decade of HAART
    • Shafer R, Schapiro J. HIV-1 drug resistance mutations: An updated framework for the second decade of HAART. AIDS Rev. 2008;10(2):67-84.
    • (2008) AIDS Rev , vol.10 , Issue.2 , pp. 67-84
    • Shafer, R.1    Schapiro, J.2
  • 13
    • 59549102999 scopus 로고    scopus 로고
    • The CASTLE study 48 weeks results: The impact of HIV subtypes and baseline resistance on treatment outcomes and the emergence of resistance
    • for the BMS-AI424138 Study Group
    • Lataillade M, Molina JM, Thiry A, Mancini M, McGrath D, for the BMS-AI424138 Study Group. The CASTLE study 48 weeks results: The impact of HIV subtypes and baseline resistance on treatment outcomes and the emergence of resistance. Antivir Ther. 2008;13 suppl 3:A135.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Lataillade, M.1    Molina, J.M.2    Thiry, A.3    Mancini, M.4    McGrath, D.5
  • 14
    • 0041733063 scopus 로고    scopus 로고
    • Atazanavir
    • Goldsmith D, Perry C. Atazanavir. Drugs. 2003;63(16):1679-93.
    • (2003) Drugs , vol.63 , Issue.16 , pp. 1679-1693
    • Goldsmith, D.1    Perry, C.2
  • 15
    • 33750597597 scopus 로고    scopus 로고
    • Population pharmacokinetics of atazanavir in patients with HIV infection
    • Colombo S, Buclin T, Cavassini M, et al. Population pharmacokinetics of atazanavir in patients with HIV infection. Antimicrob Agents Chemother. 2006;50(11):3801-3808.
    • (2006) Antimicrob Agents Chemother , vol.50 , Issue.11 , pp. 3801-3808
    • Colombo, S.1    Buclin, T.2    Cavassini, M.3
  • 16
    • 38849116827 scopus 로고    scopus 로고
    • The PATCG 1020 protocol: Atazanavir with or without ritonavir in HIV-infected infants, children, and adolescents
    • February 3-5; Los Angeles, USA; Abstract 715
    • Rutstein R, Samson P, Kiser J, et al. The PATCG 1020 protocol: Atazanavir with or without ritonavir in HIV-infected infants, children, and adolescents. 14th Conference on Retroviruses and Opportunistic Infections (CROI). 2007 February 3-5; Los Angeles, USA; Abstract 715.
    • (2007) 14th Conference on Retroviruses and Opportunistic Infections (CROI)
    • Rutstein, R.1    Samson, P.2    Kiser, J.3
  • 17
    • 33947430611 scopus 로고    scopus 로고
    • Influence of liver fibrosis stage on plasma levels of antiretroviral drugs in HIV-infected patients with chronic hepatitis C
    • Barreiro P, Rodriguez-Novoa S, Labarga P, et al. Influence of liver fibrosis stage on plasma levels of antiretroviral drugs in HIV-infected patients with chronic hepatitis C. J Infect Dis. 2007;195(7):973-979.
    • (2007) J Infect Dis , vol.195 , Issue.7 , pp. 973-979
    • Barreiro, P.1    Rodriguez-Novoa, S.2    Labarga, P.3
  • 18
    • 10944246142 scopus 로고    scopus 로고
    • Pharmacokinetics of antiretrovirals in pregnant women
    • Mirochnick M, Capparelli E. Pharmacokinetics of antiretrovirals in pregnant women. Clin Pharmacokinet. 2004;43(15):1071-1087.
    • (2004) Clin Pharmacokinet , vol.43 , Issue.15 , pp. 1071-1087
    • Mirochnick, M.1    Capparelli, E.2
  • 19
    • 77949466546 scopus 로고    scopus 로고
    • Steady state pharmacokinetics and safety of atazanavir after treatment with ATV 300 mg once daily/Ritonavir 100 mg once daily + ZDV/3TC during the third trimester in HIV+ women
    • Feb 3-6; Boston, USA; Abstract 624
    • Eley T, Vandeloise E, Child M, et al. Steady state pharmacokinetics and safety of atazanavir after treatment with ATV 300 mg once daily/Ritonavir 100 mg once daily + ZDV/3TC during the third trimester in HIV+ women. 15th Conference on Retroviruses and Opportunistic Infections (CROI). 2008 Feb 3-6; Boston, USA; Abstract 624.
    • (2008) 15th Conference on Retroviruses and Opportunistic Infections (CROI)
    • Eley, T.1    Vandeloise, E.2    Child, M.3
  • 22
    • 18844409566 scopus 로고    scopus 로고
    • Atazanavir: Effects on P-glycoprotein transport and CYP3A metabolism in vitro
    • Perloff E, Duan S, Skolnik P, Greenblatt D, von Moltke L. Atazanavir: Effects on P-glycoprotein transport and CYP3A metabolism in vitro. Drug Metab Dispos. 2005;33(6):764-770.
    • (2005) Drug Metab Dispos , vol.33 , Issue.6 , pp. 764-770
    • Perloff, E.1    Duan, S.2    Skolnik, P.3    Greenblatt, D.4    von Moltke, L.5
  • 23
    • 34249876574 scopus 로고    scopus 로고
    • Updated guidelines to perform therapeutic drug monitoring for antiretroviral agents
    • La Prote C, Back D, Blaschke T, et al. Updated guidelines to perform therapeutic drug monitoring for antiretroviral agents. Rev Antivir Ther. 2006;3:3-14.
    • (2006) Rev Antivir Ther , vol.3 , pp. 3-14
    • La Prote, C.1    Back, D.2    Blaschke, T.3
  • 24
    • 77949478682 scopus 로고    scopus 로고
    • Department of Health and Human Services. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. January 29, 2008;1-128. [Accessed 31 August 2008]. Available from: http://www.aidsinfo.nih. gov/ContentFiles/AdultandAdolescentGL.pdf
    • Department of Health and Human Services. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. January 29, 2008;1-128. [Accessed 31 August 2008]. Available from: http://www.aidsinfo.nih. gov/ContentFiles/AdultandAdolescentGL.pdf
  • 25
    • 77949433208 scopus 로고    scopus 로고
    • Gonzalez de Requena D, Bonora S, Cavechia I. Atazanavir Ctrough is associated with efficacy and safety at 24 weeks: Definition of therapeutic range. 6th International Workshop on Clinical Pharmacology of HIV Therapy. April 28-30 2005; Quebec City, Quebec, Canada; Abstract 60.
    • Gonzalez de Requena D, Bonora S, Cavechia I. Atazanavir Ctrough is associated with efficacy and safety at 24 weeks: Definition of therapeutic range. 6th International Workshop on Clinical Pharmacology of HIV Therapy. April 28-30 2005; Quebec City, Quebec, Canada; Abstract 60.
  • 26
    • 33745792782 scopus 로고    scopus 로고
    • Virological responses to atazanavir-ritonavir-based regimens: Resistance substitutions score and pharmacokinetic parameters (Reyaphar study)
    • Pellegrin I, Breilh D, Ragnaud JM, et al. Virological responses to atazanavir-ritonavir-based regimens: resistance substitutions score and pharmacokinetic parameters (Reyaphar study). Antivir Ther. 2006;11(4):421-429.
    • (2006) Antivir Ther , vol.11 , Issue.4 , pp. 421-429
    • Pellegrin, I.1    Breilh, D.2    Ragnaud, J.M.3
  • 27
    • 33645096370 scopus 로고    scopus 로고
    • Clinical pharmacodynamics of HIV-1 protease inhibitors: Use of inhibitory quotients to optimise pharmacotherapy
    • Morse G, Catanzaro L, Acosta E. Clinical pharmacodynamics of HIV-1 protease inhibitors: Use of inhibitory quotients to optimise pharmacotherapy. Lancet Infect Dis. 2006;6(4):215-225.
    • (2006) Lancet Infect Dis , vol.6 , Issue.4 , pp. 215-225
    • Morse, G.1    Catanzaro, L.2    Acosta, E.3
  • 28
    • 29144452574 scopus 로고    scopus 로고
    • The normalized inhibitory quotient of boosted protease inhibitors is predictive of viral load response in treatment-experienced HIV-1-infected individuals
    • Winston A, Hales G, Amin J, et al. The normalized inhibitory quotient of boosted protease inhibitors is predictive of viral load response in treatment-experienced HIV-1-infected individuals. AIDS. 2005;19(13):1393-1399.
    • (2005) AIDS , vol.19 , Issue.13 , pp. 1393-1399
    • Winston, A.1    Hales, G.2    Amin, J.3
  • 29
    • 30144438738 scopus 로고    scopus 로고
    • Plasma levels of atazanavir and the risk of hyperbilirubinemia are predicted by the 3435C ->T polymorphism at the multidrug resistance gene 1
    • Rodriguez Novoa S, Barreiro P, Rendon A, et al. Plasma levels of atazanavir and the risk of hyperbilirubinemia are predicted by the 3435C ->T polymorphism at the multidrug resistance gene 1. Clin Infect Dis. 2006;42(2):291-295.
    • (2006) Clin Infect Dis , vol.42 , Issue.2 , pp. 291-295
    • Rodriguez Novoa, S.1    Barreiro, P.2    Rendon, A.3
  • 30
    • 33845495422 scopus 로고    scopus 로고
    • Genetic factors influencing atazanavir plasma concentrations and the risk of severe hyperbilirubinemia
    • Rodriguez-Novoa S, Martin-Carbonero L, Barreiro P, et al. Genetic factors influencing atazanavir plasma concentrations and the risk of severe hyperbilirubinemia. AIDS. 2007;21(1):41-46.
    • (2007) AIDS , vol.21 , Issue.1 , pp. 41-46
    • Rodriguez-Novoa, S.1    Martin-Carbonero, L.2    Barreiro, P.3
  • 31
    • 57349138829 scopus 로고    scopus 로고
    • Increase in serum bilirubin in HIV/HCV coinfected patients on stable atazanavir therapy following initiation of peginterferon plus ribavirin
    • in press
    • Rodriguez-Novoa S, Morello J, González M, et al. Increase in serum bilirubin in HIV/HCV coinfected patients on stable atazanavir therapy following initiation of peginterferon plus ribavirin. AIDS. 2008 (in press).
    • (2008) AIDS
    • Rodriguez-Novoa, S.1    Morello, J.2    González, M.3
  • 32
    • 2542502584 scopus 로고    scopus 로고
    • Interactions between atazanavir-ritonavir and tenofovir in heavily pretreated HIV-infected patients
    • Taburet A, Piketty C, Chazallon C, et al. Interactions between atazanavir-ritonavir and tenofovir in heavily pretreated HIV-infected patients. Antimicrob Agents Chemother. 2004;48(6):2091-2096.
    • (2004) Antimicrob Agents Chemother , vol.48 , Issue.6 , pp. 2091-2096
    • Taburet, A.1    Piketty, C.2    Chazallon, C.3
  • 33
    • 33646744190 scopus 로고    scopus 로고
    • 96-week comparison of once-daily Atazanavir/ritonavir and twice-daily Lopinavir/ritonavir in patients with multiple virologic failures
    • Johnson M, Grinsztejn B, Rodriguez C, et al. 96-week comparison of once-daily Atazanavir/ritonavir and twice-daily Lopinavir/ritonavir in patients with multiple virologic failures. AIDS. 2006;20(5):711-718.
    • (2006) AIDS , vol.20 , Issue.5 , pp. 711-718
    • Johnson, M.1    Grinsztejn, B.2    Rodriguez, C.3
  • 34
    • 45749127878 scopus 로고    scopus 로고
    • Switch from ritonavir-boosted to unboosted atazanavir guided by therapeutic drug monitoring
    • Rodriguez-Novoa S, Morello J, Barreiro P, et al. Switch from ritonavir-boosted to unboosted atazanavir guided by therapeutic drug monitoring. AIDS Res Hum Retroviruses. 2008;24(6):821-825.
    • (2008) AIDS Res Hum Retroviruses , vol.24 , Issue.6 , pp. 821-825
    • Rodriguez-Novoa, S.1    Morello, J.2    Barreiro, P.3
  • 35
    • 0028875109 scopus 로고
    • Specificity of human UDP-glucuronosyltransferases and xenobiotic glucuronidation
    • Burchell B, Brierley C, Rance D. Specificity of human UDP-glucuronosyltransferases and xenobiotic glucuronidation. Life Sci. 1995;57(20):1819-1831.
    • (1995) Life Sci , vol.57 , Issue.20 , pp. 1819-1831
    • Burchell, B.1    Brierley, C.2    Rance, D.3
  • 36
    • 27544468948 scopus 로고    scopus 로고
    • In vitro inhibition of UDP glucuronosyltransferases by atazanavir and other HIV protease inhibitors and the relationship of this property to in vivo bilirubin glucuronidation
    • Zhang D, Chando T, Everett D, Patten C, Dehal S, Humphreys W. In vitro inhibition of UDP glucuronosyltransferases by atazanavir and other HIV protease inhibitors and the relationship of this property to in vivo bilirubin glucuronidation. Drug Metab Dispos. 2005;33(11):1729-1739.
    • (2005) Drug Metab Dispos , vol.33 , Issue.11 , pp. 1729-1739
    • Zhang, D.1    Chando, T.2    Everett, D.3    Patten, C.4    Dehal, S.5    Humphreys, W.6
  • 37
    • 0034724324 scopus 로고    scopus 로고
    • Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
    • Hoffmeyer S, Burk O, von Richter O, et al. Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc Natl Acad Sci U S A. 2000;97(7):3473-3478.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , Issue.7 , pp. 3473-3478
    • Hoffmeyer, S.1    Burk, O.2    von Richter, O.3
  • 38
    • 10744222684 scopus 로고    scopus 로고
    • Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene
    • Kroetz D, Pauli-Magnus C, Hodges L, et al. Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene. Pharmacogenetics. 2003;13(8):481-494.
    • (2003) Pharmacogenetics , vol.13 , Issue.8 , pp. 481-494
    • Kroetz, D.1    Pauli-Magnus, C.2    Hodges, L.3
  • 39
    • 33645876468 scopus 로고    scopus 로고
    • MDR1 genotype is associated with hepatic cytochrome P450 3A4 basal and induction phenotype
    • Lamba J, Strom S, Venkataramanan R, et al. MDR1 genotype is associated with hepatic cytochrome P450 3A4 basal and induction phenotype. Clin Pharmacol Ther. 2006;79(4):325-338.
    • (2006) Clin Pharmacol Ther , vol.79 , Issue.4 , pp. 325-338
    • Lamba, J.1    Strom, S.2    Venkataramanan, R.3
  • 40
    • 17044450136 scopus 로고    scopus 로고
    • Frequent co-occurrence of the TATA box mutation associated with Gilbert's syndrome (UGT1A1*28) with other polymorphisms of the UDP-glucuronosyltransferase-1 locus (UGT1A6*2 and UGT1A7*3) in Caucasians and Egyptians
    • Kohle C, Mohrle B, Munzel P, et al. Frequent co-occurrence of the TATA box mutation associated with Gilbert's syndrome (UGT1A1*28) with other polymorphisms of the UDP-glucuronosyltransferase-1 locus (UGT1A6*2 and UGT1A7*3) in Caucasians and Egyptians. Biochem Pharmacol. 2003;65(9):1521-1527.
    • (2003) Biochem Pharmacol , vol.65 , Issue.9 , pp. 1521-1527
    • Kohle, C.1    Mohrle, B.2    Munzel, P.3
  • 41
    • 33751005307 scopus 로고    scopus 로고
    • Gilbert's disease and atazanavir: From phenotype to UDP-glucuronosyltransferase haplotype
    • Lankisch T, Moebius U, Wehmeier M, et al. Gilbert's disease and atazanavir: from phenotype to UDP-glucuronosyltransferase haplotype. Hepatology. 2006;44(5):1324-1332.
    • (2006) Hepatology , vol.44 , Issue.5 , pp. 1324-1332
    • Lankisch, T.1    Moebius, U.2    Wehmeier, M.3
  • 42
    • 25844446183 scopus 로고    scopus 로고
    • Gilbert syndrome and the development of antiretroviral therapy-associated hyperbilirubinemia
    • Rotger M, Taffe P, Bleiber G, et al. Gilbert syndrome and the development of antiretroviral therapy-associated hyperbilirubinemia. J Infect Dis. 2005;192(8):1381-1386.
    • (2005) J Infect Dis , vol.192 , Issue.8 , pp. 1381-1386
    • Rotger, M.1    Taffe, P.2    Bleiber, G.3
  • 43
    • 0037234238 scopus 로고    scopus 로고
    • Sanne I, Piliero P, Squires K, Thiry A, Schnittman S, AI424-007 Clinical Trial Group. Results of a phase 2 clinical trial at 48 weeks (AI424-007): A dose-ranging, safety, and efficacy comparative trial of atazanavir at three doses in combination with didanosine and stavudine in antiretroviral-naive subjects. J Acquir Immune Defic Syndr. 2003;32(1):18-29.
    • Sanne I, Piliero P, Squires K, Thiry A, Schnittman S, AI424-007 Clinical Trial Group. Results of a phase 2 clinical trial at 48 weeks (AI424-007): A dose-ranging, safety, and efficacy comparative trial of atazanavir at three doses in combination with didanosine and stavudine in antiretroviral-naive subjects. J Acquir Immune Defic Syndr. 2003;32(1):18-29.
  • 44
    • 1642465026 scopus 로고    scopus 로고
    • Dose-ranging, randomized, clinical trial of atazanavir with lamivudine and stavudine in antiretroviral-naive subjects: 48-week results
    • Murphy R, Sanne I, Cahn P, et al. Dose-ranging, randomized, clinical trial of atazanavir with lamivudine and stavudine in antiretroviral-naive subjects: 48-week results. AIDS. 2003;17(18):2603-2614.
    • (2003) AIDS , vol.17 , Issue.18 , pp. 2603-2614
    • Murphy, R.1    Sanne, I.2    Cahn, P.3
  • 45
  • 46
    • 33744490677 scopus 로고    scopus 로고
    • A prospective evaluation of the effect of atazanavir on the QTc interval and QTc dispersion in HIV-positive patients
    • Busti A, Tsikouris J, Peeters M, et al. A prospective evaluation of the effect of atazanavir on the QTc interval and QTc dispersion in HIV-positive patients. HIV Med. 2006;7(5):317-322.
    • (2006) HIV Med , vol.7 , Issue.5 , pp. 317-322
    • Busti, A.1    Tsikouris, J.2    Peeters, M.3
  • 47
    • 34447566881 scopus 로고    scopus 로고
    • Electrocardiographic changes in HIV-infected, drug-experienced patients being treated with atazanavir
    • Gianotti N, Guffanti M, Galli L, et al. Electrocardiographic changes in HIV-infected, drug-experienced patients being treated with atazanavir. AIDS. 2007;21(12):1648-1651.
    • (2007) AIDS , vol.21 , Issue.12 , pp. 1648-1651
    • Gianotti, N.1    Guffanti, M.2    Galli, L.3
  • 48
    • 33750971719 scopus 로고    scopus 로고
    • Atazanavir urolithiasis
    • Chang H, Pella P. Atazanavir urolithiasis. N Engl J Med. 2006;355(20):2158-2159.
    • (2006) N Engl J Med , vol.355 , Issue.20 , pp. 2158-2159
    • Chang, H.1    Pella, P.2
  • 49
    • 34848881299 scopus 로고    scopus 로고
    • Urolithiasis in HIV-positive patients treated with atazanavir
    • Couzigou C, Daudon M, Meynard J, et al. Urolithiasis in HIV-positive patients treated with atazanavir. Clin Infect Dis. 2007;45(8):e105-8.
    • (2007) Clin Infect Dis , vol.45 , Issue.8
    • Couzigou, C.1    Daudon, M.2    Meynard, J.3
  • 50
    • 42549159124 scopus 로고    scopus 로고
    • Atazanavir/ritonavir: A review of its use in HIV therapy
    • von Hentig N. Atazanavir/ritonavir: A review of its use in HIV therapy. Drugs Today (Barc). 2008;44(2):103-132.
    • (2008) Drugs Today (Barc) , vol.44 , Issue.2 , pp. 103-132
    • von Hentig, N.1
  • 51
    • 38649100026 scopus 로고    scopus 로고
    • Efficacy and safety of atazanavir, with or without ritonavir, as part of once-daily highly active antiretroviral therapy regimens in antiretroviral-naive patients
    • Malan D, Krantz E, David N, et al. Efficacy and safety of atazanavir, with or without ritonavir, as part of once-daily highly active antiretroviral therapy regimens in antiretroviral-naive patients. J Acquir Immune Defic Syndr. 2008;47:161-167.
    • (2008) J Acquir Immune Defic Syndr , vol.47 , pp. 161-167
    • Malan, D.1    Krantz, E.2    David, N.3
  • 52
    • 48949097660 scopus 로고    scopus 로고
    • Antiretroviral treatment of adult HIV infection: 2008 recommendations of the international AIDS society-USA panel
    • Hammer S, Eron J, Reiss P, et al. Antiretroviral treatment of adult HIV infection: 2008 recommendations of the international AIDS society-USA panel. JAMA. 2008;300:555-570.
    • (2008) JAMA , vol.300 , pp. 555-570
    • Hammer, S.1    Eron, J.2    Reiss, P.3
  • 53
    • 77949434293 scopus 로고    scopus 로고
    • PEARLS (ACTG A5175): A multinational study of didanosine-EC, emtricitabine and atazanavir vs co-formulated ZDV/lamivudine and EFV for initial treatment of HIV-1 infection
    • Aug 3-8; Mexico City, Mexico; Abstract THAB0404
    • Campbell T, Smeaton L, De Grutolla V, et al. PEARLS (ACTG A5175): A multinational study of didanosine-EC, emtricitabine and atazanavir vs co-formulated ZDV/lamivudine and EFV for initial treatment of HIV-1 infection. XVII International AIDS Conference. 2008 Aug 3-8; Mexico City, Mexico; Abstract THAB0404.
    • (2008) XVII International AIDS Conference
    • Campbell, T.1    Smeaton, L.2    De Grutolla, V.3
  • 54
    • 43149106498 scopus 로고    scopus 로고
    • Fosamprenavir or atazanavir once daily boosted with ritonavir 100 mg, plus tenofovir/emtricitabine, for the initial treatment of HIV infection: 48-week results of ALERT
    • Smith K, Weinberg W, Dejesus E, et al. Fosamprenavir or atazanavir once daily boosted with ritonavir 100 mg, plus tenofovir/emtricitabine, for the initial treatment of HIV infection: 48-week results of ALERT. AIDS Res Ther. 2008;5:5.
    • (2008) AIDS Res Ther , vol.5 , pp. 5
    • Smith, K.1    Weinberg, W.2    Dejesus, E.3
  • 55
    • 49649112490 scopus 로고    scopus 로고
    • Once-daily atazanavir/ritonavir versus twice-daily lopinavir/ritonavir, each in combination with tenofovir and emtricitabine, for management of antiretroviral-naive HIV-1-infected patients: 48 week efficacy and safety results of the CASTLE study
    • Molina J, Andrade-Villanueva J, Echevarria J, et al. Once-daily atazanavir/ritonavir versus twice-daily lopinavir/ritonavir, each in combination with tenofovir and emtricitabine, for management of antiretroviral-naive HIV-1-infected patients: 48 week efficacy and safety results of the CASTLE study. Lancet. 2008;372(9639):646-655.
    • (2008) Lancet , vol.372 , Issue.9639 , pp. 646-655
    • Molina, J.1    Andrade-Villanueva, J.2    Echevarria, J.3
  • 56
    • 0037661234 scopus 로고    scopus 로고
    • Therapy with atazanavir plus saquinavir in patients failing highly active antiretroviral therapy: A randomized comparative pilot trial
    • Haas D, Zala C, Schrader S, et al. Therapy with atazanavir plus saquinavir in patients failing highly active antiretroviral therapy: A randomized comparative pilot trial. AIDS. 2003;17(9):1339-1349.
    • (2003) AIDS , vol.17 , Issue.9 , pp. 1339-1349
    • Haas, D.1    Zala, C.2    Schrader, S.3
  • 57
    • 3042636428 scopus 로고    scopus 로고
    • Atazanavir enhances saquinavir hard-gel concentrations in a ritonavir-boosted once-daily regimen
    • Boffito M, Kurowski M, Kruse G, et al. Atazanavir enhances saquinavir hard-gel concentrations in a ritonavir-boosted once-daily regimen. AIDS. 2004;18(9):1291-1297.
    • (2004) AIDS , vol.18 , Issue.9 , pp. 1291-1297
    • Boffito, M.1    Kurowski, M.2    Kruse, G.3
  • 58
    • 27144482749 scopus 로고    scopus 로고
    • Comparison of atazanavir with lopinavir/ritonavir in patients with prior protease inhibitor failure: A randomized multinational trial
    • Cohen C, Nieto-Cisneros L, Zala C, et al. Comparison of atazanavir with lopinavir/ritonavir in patients with prior protease inhibitor failure: A randomized multinational trial. Curr Med Res Opin. 2005;21(10):1683-1692.
    • (2005) Curr Med Res Opin , vol.21 , Issue.10 , pp. 1683-1692
    • Cohen, C.1    Nieto-Cisneros, L.2    Zala, C.3
  • 59
    • 22444439664 scopus 로고    scopus 로고
    • Atazanavir plus ritonavir or saquinavir, and lopinavir/ritonavir in patients experiencing multiple virological failures
    • Johnson M, Grinsztejn B, Rodriguez C, et al. Atazanavir plus ritonavir or saquinavir, and lopinavir/ritonavir in patients experiencing multiple virological failures. AIDS. 2005;19(7):685-694.
    • (2005) AIDS , vol.19 , Issue.7 , pp. 685-694
    • Johnson, M.1    Grinsztejn, B.2    Rodriguez, C.3
  • 60
    • 33750845765 scopus 로고    scopus 로고
    • Performance of six different ritonavir-boosted protease inhibitor-based regimens in heavily antiretroviral-experienced HIV-infected patients
    • de Mendoza C, Valer L, Ribera E, et al. Performance of six different ritonavir-boosted protease inhibitor-based regimens in heavily antiretroviral-experienced HIV-infected patients. HIV Clin Trials. 2006;7(4):163-171.
    • (2006) HIV Clin Trials , vol.7 , Issue.4 , pp. 163-171
    • de Mendoza, C.1    Valer, L.2    Ribera, E.3
  • 61
    • 34250828550 scopus 로고    scopus 로고
    • Antiviral activity and clinical efficacy of atazanavir in HIV-1-infected patients: A review
    • Gianotti N, Soria A, Lazzarin A. Antiviral activity and clinical efficacy of atazanavir in HIV-1-infected patients: A review. New Microbiol. 2007;30(2):79-88.
    • (2007) New Microbiol , vol.30 , Issue.2 , pp. 79-88
    • Gianotti, N.1    Soria, A.2    Lazzarin, A.3
  • 62
    • 2542489421 scopus 로고    scopus 로고
    • Long-term efficacy and safety of atazanavir with stavudine and lamivudine in patients previously treated with nelfinavir or atazanavir
    • Wood R, Phanuphak P, Cahn P, et al. Long-term efficacy and safety of atazanavir with stavudine and lamivudine in patients previously treated with nelfinavir or atazanavir. J Acquir Immune Defic Syndr. 2004;36(2):684-692.
    • (2004) J Acquir Immune Defic Syndr , vol.36 , Issue.2 , pp. 684-692
    • Wood, R.1    Phanuphak, P.2    Cahn, P.3
  • 63
    • 25844518881 scopus 로고    scopus 로고
    • AI424067: Improvement in lipid profiles after 12 weeks of switching to atazanavir from boosted or unboosted protease inhibitors in patients with no previous PI virologic failure and hyperlipidemia at baseline
    • Feb 22-25; Boston, MA, USA; Abstract 858
    • Sension M, Grinsztejn B, Molina JM, et al. AI424067: Improvement in lipid profiles after 12 weeks of switching to atazanavir from boosted or unboosted protease inhibitors in patients with no previous PI virologic failure and hyperlipidemia at baseline. 12th Conference on Retroviruses and Opportunistic Infections. 2005 Feb 22-25; Boston, MA, USA; Abstract 858.
    • (2005) 12th Conference on Retroviruses and Opportunistic Infections
    • Sension, M.1    Grinsztejn, B.2    Molina, J.M.3
  • 64
    • 77949460604 scopus 로고    scopus 로고
    • AI424067, Accessed 31 Aug, Available from
    • Bristol-Myers Squibb Company. Clinical Study Report AI424067. [Accessed 31 Aug 2008]. Available from: http://ctr.bms.com/pdf//AI424067.pdf27.
    • (2008) Clinical Study Report
  • 65
    • 34249078589 scopus 로고    scopus 로고
    • Efficacy and safety of atazanavir-based highly active antiretroviral therapy in patients with virologic suppression switched from a stable, boosted or unboosted protease inhibitor treatment regimen: The SWAN study (AI424-097) 48-week results
    • Gatell J, Salmon-Ceron D, Lazzarin A, et al. Efficacy and safety of atazanavir-based highly active antiretroviral therapy in patients with virologic suppression switched from a stable, boosted or unboosted protease inhibitor treatment regimen: The SWAN study (AI424-097) 48-week results. Clin Infect Dis. 2007;44(11):1484-1492.
    • (2007) Clin Infect Dis , vol.44 , Issue.11 , pp. 1484-1492
    • Gatell, J.1    Salmon-Ceron, D.2    Lazzarin, A.3
  • 66
    • 37549038211 scopus 로고    scopus 로고
    • Efficacy and safety of replacing lopinavir with atazanavir in HIV-infected patients with undetectable plasma viraemia: Final results of the SLOAT trial
    • Soriano V, Garcia-Gasco P, Vispo E, et al. Efficacy and safety of replacing lopinavir with atazanavir in HIV-infected patients with undetectable plasma viraemia: Final results of the SLOAT trial. J Antimicrob Chemother. 2008;61(1):200-205.
    • (2008) J Antimicrob Chemother , vol.61 , Issue.1 , pp. 200-205
    • Soriano, V.1    Garcia-Gasco, P.2    Vispo, E.3
  • 67
    • 67649145151 scopus 로고    scopus 로고
    • Efficacy and safety of switching from lopinavir/r (LPV/r) to atazanavir/r (ATV/r) in patients with virologic suppression receiving a LPV/r containing HAART: The ATAZIP study
    • July 22-25; Sydney, Australia; Abstract WEPEB117LB
    • Mallolas J, Podzamczer D, Domingo P, et al. Efficacy and safety of switching from lopinavir/r (LPV/r) to atazanavir/r (ATV/r) in patients with virologic suppression receiving a LPV/r containing HAART: The ATAZIP study. 4th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention. 2007 July 22-25; Sydney, Australia; Abstract WEPEB117LB.
    • (2007) 4th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention
    • Mallolas, J.1    Podzamczer, D.2    Domingo, P.3
  • 68
    • 33748510777 scopus 로고    scopus 로고
    • Effects of atazanavir/ritonavir and lopinavir/ritonavir on glucose uptake and insulin sensitivity: Demonstrable differences in vitro and clinically
    • Noor M, Flint O, Maa J, Parker R. Effects of atazanavir/ritonavir and lopinavir/ritonavir on glucose uptake and insulin sensitivity: Demonstrable differences in vitro and clinically. AIDS. 2006;20(14):1813-1821.
    • (2006) AIDS , vol.20 , Issue.14 , pp. 1813-1821
    • Noor, M.1    Flint, O.2    Maa, J.3    Parker, R.4
  • 69
    • 34247629373 scopus 로고    scopus 로고
    • Switching to unboosted atazanavir improves glucose tolerance in highly pretreated HIV-1 infected subjects
    • Guffanti M, Caumo A, Galli L, et al. Switching to unboosted atazanavir improves glucose tolerance in highly pretreated HIV-1 infected subjects. Eur J Endocrinol. 2007;156(4):503-509.
    • (2007) Eur J Endocrinol , vol.156 , Issue.4 , pp. 503-509
    • Guffanti, M.1    Caumo, A.2    Galli, L.3
  • 70
    • 85047681377 scopus 로고    scopus 로고
    • Improvement in insulin sensitivity and dyslipidemia in protease inhibitor-treated adult male patients after switch to atazanavir/ritonavir
    • Busti A, Bedimo R, Margolis D, Hardin D. Improvement in insulin sensitivity and dyslipidemia in protease inhibitor-treated adult male patients after switch to atazanavir/ritonavir. J Investig Med. 2008;56(2):539-544.
    • (2008) J Investig Med , vol.56 , Issue.2 , pp. 539-544
    • Busti, A.1    Bedimo, R.2    Margolis, D.3    Hardin, D.4
  • 71
    • 30144443508 scopus 로고    scopus 로고
    • Body fat and other metabolic effects of atazanavir and EFV, each administered in combination with ZDV plus lamivudine, in antiretroviral-naive HIV-infected patients
    • Jemsek J, Arathoon E, Arlotti M, et al. Body fat and other metabolic effects of atazanavir and EFV, each administered in combination with ZDV plus lamivudine, in antiretroviral-naive HIV-infected patients. Clin Infect Dis. 2006;42(2):273-280.
    • (2006) Clin Infect Dis , vol.42 , Issue.2 , pp. 273-280
    • Jemsek, J.1    Arathoon, E.2    Arlotti, M.3
  • 72
    • 2142762984 scopus 로고    scopus 로고
    • Regression of lipodystrophy in HIV-infected patients under therapy with the new protease inhibitor atazanavir
    • Haerter G, Manfras B, Mueller M, Kern P, Trein A. Regression of lipodystrophy in HIV-infected patients under therapy with the new protease inhibitor atazanavir. AIDS. 2004;18(6):952-955.
    • (2004) AIDS , vol.18 , Issue.6 , pp. 952-955
    • Haerter, G.1    Manfras, B.2    Mueller, M.3    Kern, P.4    Trein, A.5
  • 73
    • 67049150602 scopus 로고    scopus 로고
    • Continuation of BID boosted PI vs switch to once-daily ATV/RTV for the management of lipodystrophy: 48 week primary analysis of the 96 week multicenter, open-label, randomized, prospective ReAL study
    • August 3-8; Mexico City, Mexico; Abstract MOPDB103
    • Moyle G, Girard J, Andrade J, et al. Continuation of BID boosted PI vs switch to once-daily ATV/RTV for the management of lipodystrophy: 48 week primary analysis of the 96 week multicenter, open-label, randomized, prospective ReAL study. XVII International AIDS Conference. 2008 August 3-8; Mexico City, Mexico; Abstract MOPDB103.
    • (2008) XVII International AIDS Conference
    • Moyle, G.1    Girard, J.2    Andrade, J.3
  • 74
    • 39649121267 scopus 로고    scopus 로고
    • Cardiovascular risk score change in HIV-1-infected patients switched to an atazanavir-based combination antiretroviral regimen
    • Colafigli M, Di Giambenedetto S, Bracciale L, Tamburrini E, Cauda R, De Luca A. Cardiovascular risk score change in HIV-1-infected patients switched to an atazanavir-based combination antiretroviral regimen. HIV Med. 2008;9(3):172-179.
    • (2008) HIV Med , vol.9 , Issue.3 , pp. 172-179
    • Colafigli, M.1    Di Giambenedetto, S.2    Bracciale, L.3    Tamburrini, E.4    Cauda, R.5    De Luca, A.6
  • 75
    • 61949412515 scopus 로고    scopus 로고
    • Effect of atazanavir versus other protease inhibitor-containing antiretroviral therapy on endothelial function in HIV-infected persons: Randomized controlled trial
    • in press
    • Flammer A, Vo N, Ledergerber B, et al. Effect of atazanavir versus other protease inhibitor-containing antiretroviral therapy on endothelial function in HIV-infected persons: Randomized controlled trial. Heart (in press).
    • Heart
    • Flammer, A.1    Vo, N.2    Ledergerber, B.3
  • 76
    • 27444444039 scopus 로고    scopus 로고
    • Lopinavir/ritonavir as single-drug therapy for maintenance of HIV-1 viral suppression: 48-week results of a randomized, controlled, open-label, proof-ofconcept pilot clinical trial (OK study)
    • Arribas JR, Pulido F, Delgado R, et al. Lopinavir/ritonavir as single-drug therapy for maintenance of HIV-1 viral suppression: 48-week results of a randomized, controlled, open-label, proof-ofconcept pilot clinical trial (OK study). J Acquir Immune Defic Syndr. 2005;40(3):280-287.
    • (2005) J Acquir Immune Defic Syndr , vol.40 , Issue.3 , pp. 280-287
    • Arribas, J.R.1    Pulido, F.2    Delgado, R.3
  • 77
    • 37549030881 scopus 로고    scopus 로고
    • Lopinavir-ritonavir monotherapy versus lopinavir-ritonavir and two nucleosides for maintenance therapy of HIV
    • Pulido F, Arribas JR, Delgado R, et al. Lopinavir-ritonavir monotherapy versus lopinavir-ritonavir and two nucleosides for maintenance therapy of HIV. AIDS. 2008;22(2):F1-9.
    • (2008) AIDS , vol.22 , Issue.2
    • Pulido, F.1    Arribas, J.R.2    Delgado, R.3
  • 78
    • 33747132954 scopus 로고    scopus 로고
    • Regimen simplification to atazanavir-ritonavir alone as maintenance antiretroviral therapy after sustained virologic suppression
    • Swindells S, DiRienzo AG, Wilkin T, et al. Regimen simplification to atazanavir-ritonavir alone as maintenance antiretroviral therapy after sustained virologic suppression. JAMA. 2006;296(7):806-814.
    • (2006) JAMA , vol.296 , Issue.7 , pp. 806-814
    • Swindells, S.1    DiRienzo, A.G.2    Wilkin, T.3
  • 79
    • 34147096424 scopus 로고    scopus 로고
    • Early virologic rebound in a pilot trial of ritonavir-boosted atazanavir as maintenance monotherapy
    • Karlstrom O, Josephson F, Sonnerborg A. Early virologic rebound in a pilot trial of ritonavir-boosted atazanavir as maintenance monotherapy. J Acquir Immune Defic Syndr. 2007;44(4):417-422.
    • (2007) J Acquir Immune Defic Syndr , vol.44 , Issue.4 , pp. 417-422
    • Karlstrom, O.1    Josephson, F.2    Sonnerborg, A.3
  • 80
    • 34250025874 scopus 로고    scopus 로고
    • The role of compartment penetration in PI-monotherapy: The atazanavir-ritonavir monomaintenance (ATARITMO) trial
    • Vernazza P, Daneel S, Schiffer V, et al. The role of compartment penetration in PI-monotherapy: The atazanavir-ritonavir monomaintenance (ATARITMO) trial. AIDS. 2007;21(10):1309-1315.
    • (2007) AIDS , vol.21 , Issue.10 , pp. 1309-1315
    • Vernazza, P.1    Daneel, S.2    Schiffer, V.3
  • 81
    • 42149171256 scopus 로고    scopus 로고
    • Ritonavir-boosted protease inhibitor monotherapy for the treatment of HIV-1 infection
    • Sahali S, Chaix ML, Delfraissy JF, Ghosn J. Ritonavir-boosted protease inhibitor monotherapy for the treatment of HIV-1 infection. AIDS Rev. 2008;10(1):4-14.
    • (2008) AIDS Rev , vol.10 , Issue.1 , pp. 4-14
    • Sahali, S.1    Chaix, M.L.2    Delfraissy, J.F.3    Ghosn, J.4
  • 82
    • 29144526047 scopus 로고    scopus 로고
    • Clinical validation of atazanavir/ritonavir genotypic resistance score in protease inhibitorexperienced patients
    • Vora S, Marcelin AG, Gunthard H, et al. Clinical validation of atazanavir/ritonavir genotypic resistance score in protease inhibitorexperienced patients. AIDS. 2006;20(1):35-40.
    • (2006) AIDS , vol.20 , Issue.1 , pp. 35-40
    • Vora, S.1    Marcelin, A.G.2    Gunthard, H.3
  • 83
    • 33846460075 scopus 로고    scopus 로고
    • Different patterns of mutations involved in the genotypic resistance score for atazanavir boosted versus atazanavir unboosted in multiply failing patients
    • Bertoli A, Santoro MM, Lorenzini P, et al. Different patterns of mutations involved in the genotypic resistance score for atazanavir boosted versus atazanavir unboosted in multiply failing patients. Antivir Ther. 2006;11 suppl 1:S99.
    • (2006) Antivir Ther , vol.11 , Issue.SUPPL. 1
    • Bertoli, A.1    Santoro, M.M.2    Lorenzini, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.