Synthesis and anti-osteoporotic evaluation of certain 3-amino-2-hydroxypropoxyisoflavone derivatives

European Journal of Medicinal Chemistry

Volumn 44, Issue 9, 2009, Pages 3621-3626

  Tseng, Chih Hua ^a   Chen, Yeh Long ^a   Lu, Chih Ming ^a   Wang, Chih Kuang ^a   Tsai, Yin Tung ^a   Lin, Ru Wei ^a   Chen, Chain Fu ^a   Chang, Yu Fang ^a   Wang, Gwo Jaw ^a,b   Ho, Mei Ling ^a,b   Tzeng, Cherng Chyi ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

3 Amino 2 hydroxypropoxyisoflavone; Anti osteoporotic activity; Isoflavone

Indexed keywords

3 (3,4 DIMETHOXYPHENYL) 7 (OXIRAN 2 YLMETHOXY) 4H CHROMEN 4 ONE; 3 [4 [3 (CYCLOHEXYLAMINO) 2 HYDROXYPROPOXY]PHENYL] 7 METHOXY 4H CHROMEN 4 ONE; 3 AMINO 2 HYDROXYPROPOXYISOFLAVONE DERIVATIVE; ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; IPRIFLAVONE; ISOFLAVONE DERIVATIVE; RALOXIFENE; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; ANIMAL CELL; ARTICLE; BONE DEVELOPMENT; BONE MARROW CELL; BONE MINERALIZATION; CELL DIFFERENTIATION; CELL LINE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MESENCHYME CELL; MOUSE; NONHUMAN; OSTEOBLAST; OSTEOCLAST;

ADIPOSE TISSUE; ANIMALS; BONE MARROW CELLS; CALCIFICATION, PHYSIOLOGIC; CELL DIFFERENTIATION; CELL LINE; CELL SURVIVAL; CELLS, CULTURED; HUMANS; ISOFLAVONES; MESODERM; MICE; MICE, INBRED C57BL; OSTEOBLASTS; OSTEOGENESIS; STEM CELLS;

EID: 67650441731     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.02.025     Document Type: Article

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