Amyloid protofibrils of lysozyme nucleate and grow via oligomer fusion

Biophysical Journal

Volumn 96, Issue 9, 2009, Pages 3781-3790

  Hill, Shannon E ^a   Robinson, Joshua ^a   Matthews, Garrett ^a   Muschol, Martin ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID; LYSOZYME; OLIGOMER; HEN EGG LYSOZYME;

ARTICLE; ATOMIC FORCE MICROSCOPY; CALIBRATION; CELL AGGREGATION; CELL DEATH; CELL GROWTH; CELL STRUCTURE; GROWTH; LIGHT SCATTERING; NERVE CELL; OLIGOMERIZATION; ANIMAL; CHEMISTRY; CHICKEN; KINETICS; LIGHT; METABOLISM; PROTEIN MULTIMERIZATION; RADIATION SCATTERING; TEMPERATURE; ULTRASTRUCTURE;

AMYLOID; ANIMALS; CHICKENS; KINETICS; LIGHT; MICROSCOPY, ATOMIC FORCE; MURAMIDASE; PROTEIN MULTIMERIZATION; SCATTERING, RADIATION; TEMPERATURE;

EID: 67650403403     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2009.01.044     Document Type: Article

References (34)

1. Ross, C. A., and M. A. Poirier. 2004. Protein aggregation and neurodegenerative disease. Nat. Med. 10:S10-S17.
2. Uversky, V. N., A. Talapatra, J. R. Gillespie, and A. L. Fink. 1999. Protein deposits at the molecular basis of amyloidosis. Part I. Systemic amyloidoses. Med. Sci. Monit. 5:1001-1012.
3. Sunde, M., and C. C. F. Blake. 1997. The structure of amyloid fibrils by electron microscopy and x-ray diffraction. Adv. Protein Chem. 50:123-159.
4. Jimenez, J. L., E. J. Nettleton, M. Bouchard, C. V. Robinson, C. M. Dobson, et al. 2002. The protofilament structure of insulin amyloid fibrils. Proc. Natl. Acad. Sci. USA. 99:9196-9201.
5. Dahlgren, K. N., A. M. Manelli, W. B. Stine, J. Baker, K. Lorinda, et al. 2002. Oligomeric and fibrillar species of amyloid-β peptides differentially affect neuronal viability. J. Biol. Chem. 277:36046-36053.
6. Kayed, R., E. Head, J. L. Thompson, T. M. McIntire, S. C. Milton, et al. 2003. Common structure of soluble amyloid oligomers implies common mechanism of pathogenisis. Science. 300:486-489.
7. Kodali, R., and R. Wetzel. 2007. Polymorphism in the intermediates and products of amyloid assembly. Curr. Opin. Struct. Biol. 17:48-57.
8. Chiti, F., and C. M. Dobson. 2006. Protein misfolding, functional amyloid, and human disease. Annu. Rev. Biochem. 75:333-366.
9. Serio, T. R., A. G. Cashikar, A. S. Kowal, G. J. Sawicki, J. J. Moslehi, et al. 2000. Nucleated conformational conversion and the replication of conformational information by a prion determinant. Science. 289:1317-1321.
10. Plakoutsi, G., F. Bemporad, M. Calamai, N. Taddei, C. M. Dobson, et al. 2005. Evidence for a mechanism of amyloid formation involving molecular reorganisation within native-like precursor aggregates. J. Mol. Biol. 351:910-922.
11. Collins, S. R., A. Douglass, R. D. Vale, and J. S. Weissman. 2004. Mechanism of prion propagation: amyloid growth occurs by monomer addition. PLoS Biol. 2:e321.
12. Necula, M., R. Kayed, S. Milton, and C. G. Glabe. 2007. Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct. J. Biol. Chem. 282:10311-10324.
13. Goldsbury, C., P. Frey, V. Olivieri, U. Aebi, and S. A. Müller. 2005. Multiple assembly pathways underlie amyloid-beta fibril polymorphisms. J. Mol. Biol. 352:282-298.
14. Carulla, N., G. L. Caddy, D. R. Hall, J. Zurdo, M. Gairi, et al. 2005. Molecular recycling within amyloid fibrils. Nature. 436:554-558.
15. Bitan, G., E. A. Fradinger, S. M. Spring, and D. Teplow. 2005. Neurotoxic protein oligomers - what you see is not always what you get. Amyloid. 12:88-95.
16. Kowalewski, T., and D. M. Holtzman. 1999. In situ atomic force microscopy study of Alzheimer's beta-amyloid peptide on different substrates: new insights into mechanism of beta -sheet formation. Proc. Natl. Acad. Sci. USA. 96:3688-3693.
17. Booth, D. R., M. Sunde, V. Bellotti, C. V. Robinson, W. L. Hutchinson, et al. 1997. Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis. Nature. 385:787-793.
18. Frare, E., M. F. Mossuto, P. Polverino de Laureto, M. Dumoulin, C. M. Dobson, et al. 2006. Identification of the core structure of lysozyme amyloid fibrils by proteolysis. J. Mol. Biol. 361:551-561.
19. Canet, D., M. Sunde, A. M. Last, A. Miranker, A. Spencer, et al. 1999. Mechanistic studies of the folding of human lysozyme and the origin of amyloidogenic behavior in its disease-related variants. Biochemistry. 38:6419-6427.
20. Pepys, M. B., P. N. Hawkins, D. R. Booth, D. M. Vigushin, G. A. Tennent, et al. 1993. Human lysozyme gene mutations cause hereditary systemic amyloidosis. Nature. 362:553-557.
21. Arnaudov, L. N., and R. de Vries. 2005. Thermally induced fibrillar aggregation of hen egg white lysozyme. Biophys. J. 88:515-526.
22. Parmar, A. S., P. E. Gottschall, and M. Muschol. 2007. Sub-micron lysozyme clusters distort kinetics of crystal nucleation in supersaturated lysozyme solutions. Biophys. Chem. 129:224-234.
23. Brown, W., editor. 1993. Dynamic Light Scattering: The Method and Some Applications. Oxford University Press, New York.
24. Sophianopoulos, A. J., C. K. Rhodes, D. N. Holcomb, and K. E. Van Holde. 1962. Physical studies of lysozyme. I. Characterization J. Biol. Chem. 237:1107-1112.
25. Taatjes, D. J., A. S. Quinn, M. R. Lewis, and E. G. Bovill. 1999. Quality assessment of atomic force microscopy probes by scanning electron microscopy: correlation of tip structure with rendered images. Microsc. Res. Tech. 44:312-326.
26. Zero, K., and R. Pecora. 1985. Dynamic depolarized light scattering. In Dynamic Light Scattering. R. Pecora, editor. Plenum Press, New York. 59-83.
27. Chipman, D. M., and N. Sharon. 1969. Mechanism of lysozyme action. Science. 165:454-465.
28. Dubin, S. B., N. A. Clark, and G. B. Benedek. 1971. Measurement of the rotational diffusion coefficient of lysozyme by depolarized light scattering: configuration of lysozyme in solution. J. Chem. Phys. 54:5158-5164.
29. Koo, E. H., P. T. J. Landsbury, and J. W. Kelly. 1999. Amyloid diseases: abnormal protein aggregation in neurodegeneration. Proc. Natl. Acad. Sci. USA. 96:9989-9990.
30. Perrin, F. 1936. Mouvement Brownian d'un ellipsoide. II. Rotation libre et depolarisation des fluorescences. Translation et diffusion de molecules ellipsoidales. J. Phys. Radium. 7:1-11.
31. Yong, W., A. Lomakin, M. D. Kirkitadze, D. B. Teplow, S.-H. Chen, et al. 2002. Structure determination of micelle-like intermediates in amyloid beta -protein fibril assembly by using small angle neutron scattering. Proc. Natl. Acad. Sci. USA. 99:150-154.
32. Kelly, J. W. 1996. Alternative conformations of amyloidogenic proteins govern their behavior. Curr. Opin. Struct. Biol. 6:11-17.
33. DeMarco, M. L., and V. Daggett. 2004. From conversion to aggregation: protofibril formation of the prion protein. Proc. Natl. Acad. Sci. USA. 101:2293-2298.
34. Nelson, R., M. R. Sawaya, M. Balbirnie, A. O. Madsen, C. Riekel, et al. 2005. Structure of the cross-[beta] spine of amyloid-like fibrils. Nature. 435:773-778.