C-terminal ADAMTS-18 fragment induces oxidative platelet fragmentation, dissolves platelet aggregates, and protects against carotid artery occlusion and cerebral stroke

Blood

Volumn 113, Issue 24, 2009, Pages 6051-6060

  Li, Zongdong ^a   Nardi, Michael A ^a   Li, Yong Sheng ^a   Zhang, Wei ^a   Pan, Ruimin ^a   Dang, Suying ^a   Yee, Herman ^a   Quartermain, David ^a   Jonas, Saran ^a   Karpatkin, Simon ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; COLLAGEN; FERRIC CHLORIDE; FIBRINOGEN; PROTEIN; PROTEIN ADAMTS 18; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; THROMBIN; UNCLASSIFIED DRUG; ADAM PROTEIN; ADAMTS18 PROTEIN, HUMAN; CYCLIC AMP; FIBRINOGEN RECEPTOR; PEPTIDE FRAGMENT; PEPTIDE LIBRARY; PLATELET GLYCOPROTEIN (GP)IIIA 49 66; PLATELET GLYCOPROTEIN (GP)IIIA 49-66;

ANIMAL CELL; ARTICLE; BLEEDING TIME; BRAIN INFARCTION; CARBOXY TERMINAL SEQUENCE; CAROTID ARTERY OBSTRUCTION; CAROTID ARTERY THROMBOSIS; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; THROMBOCYTE AGGREGATION; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CYTOLOGY; DRUG EFFECT; ENZYME IMMUNOASSAY; METABOLISM; MOUSE MUTANT; PATHOLOGY; POLYMERASE CHAIN REACTION; STROKE; THROMBOCYTE; UMBILICAL VEIN; VASCULAR ENDOTHELIUM;

ADAM PROTEINS; ANIMALS; BLEEDING TIME; BLOOD PLATELETS; CAROTID STENOSIS; CYCLIC AMP; ENDOTHELIUM, VASCULAR; HUMANS; IMMUNOENZYME TECHNIQUES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; PEPTIDE FRAGMENTS; PEPTIDE LIBRARY; PLATELET AGGREGATION; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; POLYMERASE CHAIN REACTION; STROKE; THROMBIN; UMBILICAL VEINS;

EID: 67650386153     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2008-07-170571     Document Type: Article

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