메뉴 건너뛰기




Volumn 21, Issue 2, 2006, Pages 218-223

Dose-dependent UV stabilization of p53 in cultured human cells undergoing apoptosis is mediated by poly(ADP-ribosyl)ation

Author keywords

Apoptosis; Caspase 3; p53; PARP; Proteasome; UV

Indexed keywords

CASPASE 3; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROTEASOME INHIBITOR; PROTEIN P53;

EID: 33646554452     PISSN: 10168478     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (14)

References (51)
  • 1
    • 0030842791 scopus 로고    scopus 로고
    • Defective induction but normal activation and function of p53 in mouse cells lacking poly-ADP-ribose polymerase
    • Agarwal, M. L., Agarwal, A., Taylor, W. R., Wang, Z. Q., Wagner, E. F., et al. (1997) Defective induction but normal activation and function of p53 in mouse cells lacking poly-ADP-ribose polymerase. Oncogene 15, 1035-1041.
    • (1997) Oncogene , vol.15 , pp. 1035-1041
    • Agarwal, M.L.1    Agarwal, A.2    Taylor, W.R.3    Wang, Z.Q.4    Wagner, E.F.5
  • 2
    • 0034818446 scopus 로고    scopus 로고
    • Post-translational modifications and activation of p53 by genotoxic stresses
    • Appella, E. and Anderson, C. W. (2001) Post-translational modifications and activation of p53 by genotoxic stresses. Eur. J. Biochem. 268, 2764-2772.
    • (2001) Eur. J. Biochem. , vol.268 , pp. 2764-2772
    • Appella, E.1    Anderson, C.W.2
  • 3
    • 0027459198 scopus 로고
    • mdm2 expression is induced by wild type p53 activity
    • Barak, Y., Juven, T., Haffner, R., and Oren, M. (1993) mdm2 expression is induced by wild type p53 activity. EMBO J. 12, 461-468.
    • (1993) EMBO J. , vol.12 , pp. 461-468
    • Barak, Y.1    Juven, T.2    Haffner, R.3    Oren, M.4
  • 4
    • 0035280982 scopus 로고    scopus 로고
    • Phosphorylation of serines 15 and 37 is necessary for efficient accumulation of p53 following irradiation with UV
    • Bean, L. J. and Stark, G. R. (2001) Phosphorylation of serines 15 and 37 is necessary for efficient accumulation of p53 following irradiation with UV. Oncogene 20, 1076-1084.
    • (2001) Oncogene , vol.20 , pp. 1076-1084
    • Bean, L.J.1    Stark, G.R.2
  • 5
    • 0037127284 scopus 로고    scopus 로고
    • Regulation of the accumulation and function of p53 by phosphorylation of two residues within the domain that binds to Mdm2
    • Bean, L. J. and Stark, G. R. (2002) Regulation of the accumulation and function of p53 by phosphorylation of two residues within the domain that binds to Mdm2. J. Biol. Chem. 277, 1864-1871.
    • (2002) J. Biol. Chem. , vol.277 , pp. 1864-1871
    • Bean, L.J.1    Stark, G.R.2
  • 6
    • 0038449141 scopus 로고    scopus 로고
    • PARP-1, a determinant of cell survival in response to DNA damage
    • Bouchard, V. J., Rouleau, M., and Poirier, G. G. (2003) PARP-1, a determinant of cell survival in response to DNA damage. Exp. Hematol. 31, 446-454.
    • (2003) Exp. Hematol. , vol.31 , pp. 446-454
    • Bouchard, V.J.1    Rouleau, M.2    Poirier, G.G.3
  • 7
    • 0028864667 scopus 로고
    • Induction of the growth inhibitor IGF-binding protein 3 by p53
    • Buckbinder, L., Talbott, R., Velasco-Miguel, S., Takenaka, I., Faha, B., et al. (1995) Induction of the growth inhibitor IGF-binding protein 3 by p53. Nature 377, 646-649.
    • (1995) Nature , vol.377 , pp. 646-649
    • Buckbinder, L.1    Talbott, R.2    Velasco-Miguel, S.3    Takenaka, I.4    Faha, B.5
  • 8
    • 0025089237 scopus 로고
    • Potentiation of carcinogen-induced methotrexate resistance and dihydrofolate reductase gene amplification by inhibitors of poly (adenosine diphosphate-ribose) polymerase
    • Burkle, A., Heilbronn, R., and zur Hausen, H. (1990) Potentiation of carcinogen-induced methotrexate resistance and dihydrofolate reductase gene amplification by inhibitors of poly (adenosine diphosphate-ribose) polymerase. Cancer Res. 50, 5756-5760.
    • (1990) Cancer Res. , vol.50 , pp. 5756-5760
    • Burkle, A.1    Heilbronn, R.2    zur Hausen, H.3
  • 9
    • 0033059183 scopus 로고    scopus 로고
    • Dose-dependent effects of DNA-damaging agents on p53-mediated cell cycle arrest
    • Chang, D., Chen, F., Zhang, F., McKay, B. C., and Ljungman, M. (1999) Dose-dependent effects of DNA-damaging agents on p53-mediated cell cycle arrest. Cell Growth Differ. 10, 155-162.
    • (1999) Cell Growth Differ. , vol.10 , pp. 155-162
    • Chang, D.1    Chen, F.2    Zhang, F.3    McKay, B.C.4    Ljungman, M.5
  • 10
    • 0842278331 scopus 로고    scopus 로고
    • Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
    • Chipuk, J. E., Kuwana, T., Bouchier-Hayes, L., Droin, N. M., Newmeyer, D. D., et al. (2004) Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis. Science 303, 1010-1014.
    • (2004) Science , vol.303 , pp. 1010-1014
    • Chipuk, J.E.1    Kuwana, T.2    Bouchier-Hayes, L.3    Droin, N.M.4    Newmeyer, D.D.5
  • 11
    • 0026642041 scopus 로고
    • Depletion of poly(ADP-ribose) polymerase by antisense RNA expression results in a delay in DNA strand break rejoining
    • Ding, R., Pommier, Y., Kang, V. H., and Smulson, M. (1992) Depletion of poly(ADP-ribose) polymerase by antisense RNA expression results in a delay in DNA strand break rejoining. J. Biol. Chem. 267, 12804-12812.
    • (1992) J. Biol. Chem. , vol.267 , pp. 12804-12812
    • Ding, R.1    Pommier, Y.2    Kang, V.H.3    Smulson, M.4
  • 13
    • 0032512057 scopus 로고    scopus 로고
    • Mdm2 association with p53 targets its ubiquitination
    • Fuchs, S. Y., Adler, V., Buschmann, T., Wu, X., and Ronai, Z. (1998) Mdm2 association with p53 targets its ubiquitination. Oncogene 17, 2543-2547.
    • (1998) Oncogene , vol.17 , pp. 2543-2547
    • Fuchs, S.Y.1    Adler, V.2    Buschmann, T.3    Wu, X.4    Ronai, Z.5
  • 14
    • 0035870123 scopus 로고    scopus 로고
    • Caspase-dependent cytosolic release of cytochrome c and membrane translocation of Bax in p53-induced apoptosis
    • Gao, C. F., Ren, S., Zhang, L., Nakajima, T., Ichinose, S., et al. (2001) Caspase-dependent cytosolic release of cytochrome c and membrane translocation of Bax in p53-induced apoptosis. Exp. Cell Res. 265, 145-151.
    • (2001) Exp. Cell Res. , vol.265 , pp. 145-151
    • Gao, C.F.1    Ren, S.2    Zhang, L.3    Nakajima, T.4    Ichinose, S.5
  • 15
    • 0032192140 scopus 로고    scopus 로고
    • The complexity of p53 modulation: Emerging patterns from divergent signals
    • Giaccia, A. J. and Kastan, M. B. (1998) The complexity of p53 modulation: emerging patterns from divergent signals. Genes Dev. 12, 2973-2983.
    • (1998) Genes Dev. , vol.12 , pp. 2973-2983
    • Giaccia, A.J.1    Kastan, M.B.2
  • 16
    • 0033604453 scopus 로고    scopus 로고
    • Overexpression of dominant negative PARP interferes with tumor formation of HeLa cells in nude mice: Evidence for increased tumor cell apoptosis in vivo
    • Hans, M. A., Muller, M., Meyer-Ficca, M., Burkle, A., and Kupper, J. H. (1999) Overexpression of dominant negative PARP interferes with tumor formation of HeLa cells in nude mice: evidence for increased tumor cell apoptosis in vivo. Oncogene 18, 7010-7015.
    • (1999) Oncogene , vol.18 , pp. 7010-7015
    • Hans, M.A.1    Muller, M.2    Meyer-Ficca, M.3    Burkle, A.4    Kupper, J.H.5
  • 17
    • 0030905284 scopus 로고    scopus 로고
    • Mdm2 promotes the rapid degradation of p53
    • Haupt Y., Maya, R., Kazaz, A., and Oren, M. (1997) Mdm2 promotes the rapid degradation of p53. Nature 387, 296-299.
    • (1997) Nature , vol.387 , pp. 296-299
    • Haupt, Y.1    Maya, R.2    Kazaz, A.3    Oren, M.4
  • 18
    • 0035796025 scopus 로고    scopus 로고
    • Functions of poly(ADP-ribose) polymerase (PARP) in DNA repair, genomic integrity and cell death
    • Herceg, Z. and Wang, Z. Q. (2001) Functions of poly(ADP-ribose) polymerase (PARP) in DNA repair, genomic integrity and cell death. Mutat. Res. 477, 97-110.
    • (2001) Mutat. Res. , vol.477 , pp. 97-110
    • Herceg, Z.1    Wang, Z.Q.2
  • 20
    • 0031583962 scopus 로고    scopus 로고
    • Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
    • Honda, R., Tanaka, H., and Yasuda, H. (1997) Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53. FEBS Lett. 420, 25-27.
    • (1997) FEBS Lett. , vol.420 , pp. 25-27
    • Honda, R.1    Tanaka, H.2    Yasuda, H.3
  • 21
    • 0642345198 scopus 로고    scopus 로고
    • DNA damage-triggered apoptosis: Critical role of DNA repair, double-strand breaks, cell proliferation and signaling
    • Kaina, B. (2003) DNA damage-triggered apoptosis: critical role of DNA repair, double-strand breaks, cell proliferation and signaling. Biochem. Pharmacol. 66, 1547-1554.
    • (2003) Biochem. Pharmacol. , vol.66 , pp. 1547-1554
    • Kaina, B.1
  • 22
    • 0032539816 scopus 로고    scopus 로고
    • Functional activation of p53 via phosphorylation following DNA damage by UV but not gamma radiation
    • Kapoor, M. and Lozano, G. (1998) Functional activation of p53 via phosphorylation following DNA damage by UV but not gamma radiation. Proc. Natl. Acad. Sci. USA 95, 2834-2837.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 2834-2837
    • Kapoor, M.1    Lozano, G.2
  • 23
    • 0026496885 scopus 로고
    • A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxiatelangiectasia
    • Kastan, M. B., Zhan, Q., el-Deiry, W. S., Carrier, F., Jacks, T., et al. (1992) A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxiatelangiectasia. Cell 71, 587-597.
    • (1992) Cell , vol.71 , pp. 587-597
    • Kastan, M.B.1    Zhan, Q.2    el-Deiry, W.S.3    Carrier, F.4    Jacks, T.5
  • 24
    • 0032443366 scopus 로고    scopus 로고
    • Determination of cell fate by c-Abl activation in the response to DNA damage
    • Kharbanda, S., Yuan, Z. M., Weichselbaum, R., and Kufe, D. (1998) Determination of cell fate by c-Abl activation in the response to DNA damage. Oncogene 17, 3309-3318.
    • (1998) Oncogene , vol.17 , pp. 3309-3318
    • Kharbanda, S.1    Yuan, Z.M.2    Weichselbaum, R.3    Kufe, D.4
  • 25
    • 0009990376 scopus 로고    scopus 로고
    • Inhibition of homodimerization of poly(ADP-ribose) polymerase by its C-terminal cleavage products produced during apoptosis
    • Kim, J. W., Kim, K., Kang, K., and Joe, C. O. (2000a) Inhibition of homodimerization of poly(ADP-ribose) polymerase by its C-terminal cleavage products produced during apoptosis. J. Biol. Chem. 275, 8121-8125.
    • (2000) J. Biol. Chem. , vol.275 , pp. 8121-8125
    • Kim, J.W.1    Kim, K.2    Kang, K.3    Joe, C.O.4
  • 26
    • 0034111148 scopus 로고    scopus 로고
    • DNA-binding activity of the N-terminal cleavage product of poly (ADP-ribose) polymerase is required for UV mediated apoptosis
    • Kim, J. W., Won, J., Sohn, S., and Joe, C. O. (2000b) DNA-binding activity of the N-terminal cleavage product of poly (ADP-ribose) polymerase is required for UV mediated apoptosis. J. Cell Sci. 113, 955-961.
    • (2000) J. Cell Sci. , vol.113 , pp. 955-961
    • Kim, J.W.1    Won, J.2    Sohn, S.3    Joe, C.O.4
  • 27
    • 0030965946 scopus 로고    scopus 로고
    • Regulation of p53 stability by Mdm2
    • Kubbutat, M. H., Jones, S. N., and Vousden, K. H. (1997) Regulation of p53 stability by Mdm2. Nature 387, 299-303.
    • (1997) Nature , vol.387 , pp. 299-303
    • Kubbutat, M.H.1    Jones, S.N.2    Vousden, K.H.3
  • 28
    • 0035845853 scopus 로고    scopus 로고
    • UV-radiation induces dose-dependent regulation of p53 response and modulates p53-HDM2 interaction in human fibroblasts
    • Latonen, L., Taya, Y., and Laiho, M. (2001) UV-radiation induces dose-dependent regulation of p53 response and modulates p53-HDM2 interaction in human fibroblasts. Oncogene 20, 6784-6793.
    • (2001) Oncogene , vol.20 , pp. 6784-6793
    • Latonen, L.1    Taya, Y.2    Laiho, M.3
  • 29
    • 0028102478 scopus 로고
    • Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE
    • Lazebnik, Y. A., Kaufmann, S. H., Desnoyers, S., Poirier, G. G., and Earnshaw, W. C. (1994) Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE. Nature 371, 346-347.
    • (1994) Nature , vol.371 , pp. 346-347
    • Lazebnik, Y.A.1    Kaufmann, S.H.2    Desnoyers, S.3    Poirier, G.G.4    Earnshaw, W.C.5
  • 30
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine, A. J. (1997) p53, the cellular gatekeeper for growth and division. Cell 88, 323-331.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 31
    • 0037184969 scopus 로고    scopus 로고
    • Acetylation of p53 inhibits its ubiquitination by Mdm2
    • Li, M., Luo, J., Brooks, C. L., and Gu, W. (2002) Acetylation of p53 inhibits its ubiquitination by Mdm2. J. Biol. Chem. 277, 50607-50611.
    • (2002) J. Biol. Chem. , vol.277 , pp. 50607-50611
    • Li, M.1    Luo, J.2    Brooks, C.L.3    Gu, W.4
  • 32
    • 0028865245 scopus 로고
    • Post-translational modification of poly(ADP-ribose) polymerase induced by DNA strand breaks
    • Lindahl, T., Satoh, M. S., Poirier, G. G., and Klungland, A. (1995) Post-translational modification of poly(ADP-ribose) polymerase induced by DNA strand breaks. Trends Biochem. Sci. 20, 405-411.
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 405-411
    • Lindahl, T.1    Satoh, M.S.2    Poirier, G.G.3    Klungland, A.4
  • 33
    • 0031015044 scopus 로고    scopus 로고
    • Ubiquitination of p53 and p2l is differentially affected by ionizing and UV radiation
    • Maki, C. G. and Howley, P. M. (1997) Ubiquitination of p53 and p2l is differentially affected by ionizing and UV radiation. Mol. Cell. Biol. 17, 355-363.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 355-363
    • Maki, C.G.1    Howley, P.M.2
  • 34
    • 0035965257 scopus 로고    scopus 로고
    • Regulation of p53 sequence-specific DNA-binding by covalent poly(ADP-ribosyl)ation
    • Mendoza-Alvarez, H. and Alvarez-Gonzalez, R. (2001) Regulation of p53 sequence-specific DNA-binding by covalent poly(ADP-ribosyl)ation. J. Biol. Chem. 276, 36425-36430.
    • (2001) J. Biol. Chem. , vol.276 , pp. 36425-36430
    • Mendoza-Alvarez, H.1    Alvarez-Gonzalez, R.2
  • 35
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
    • Miyashita, T. and Reed, J. C. (1995) Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80, 293-299.
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 36
    • 0019996840 scopus 로고
    • 3-Aminobenzamide synergistically increases sister-chromatid exchanges in cells exposed to methyl methanesulfonate but not to ultraviolet light
    • Morgan, W. F. and Cleaver, J. E. (1982) 3-Aminobenzamide synergistically increases sister-chromatid exchanges in cells exposed to methyl methanesulfonate but not to ultraviolet light. Mutat. Res. 104, 361-366.
    • (1982) Mutat. Res. , vol.104 , pp. 361-366
    • Morgan, W.F.1    Cleaver, J.E.2
  • 37
    • 0035265686 scopus 로고    scopus 로고
    • PUMA, a novel proapoptotic gene, is induced by p53
    • Nakano, K. and Vousden, K. H. (2001) PUMA, a novel proapoptotic gene, is induced by p53. Mol. Cell 7, 683-694.
    • (2001) Mol. Cell , vol.7 , pp. 683-694
    • Nakano, K.1    Vousden, K.H.2
  • 38
    • 0028339862 scopus 로고
    • Possible involvement of poly(ADP-ribosyl) polymerase in triggering stress-induced apoptosis
    • Nosseri, C., Coppola, S., and Ghibelli, L. (1994) Possible involvement of poly(ADP-ribosyl) polymerase in triggering stress-induced apoptosis. Exp. Cell Res. 212, 367-373.
    • (1994) Exp. Cell Res. , vol.212 , pp. 367-373
    • Nosseri, C.1    Coppola, S.2    Ghibelli, L.3
  • 39
    • 0032565444 scopus 로고    scopus 로고
    • Apoptin specifically causes apoptosis in tumor cells and after UV-treatment in untransformed cells from cancer-prone individuals: A review
    • Noteborn, M. H., Zhang, Y. H., and van der Eb, A. J. (1998) Apoptin specifically causes apoptosis in tumor cells and after UV-treatment in untransformed cells from cancer-prone individuals: a review. Mutat. Res. 400, 447-455.
    • (1998) Mutat. Res. , vol.400 , pp. 447-455
    • Noteborn, M.H.1    Zhang, Y.H.2    van der Eb, A.J.3
  • 40
    • 0034640281 scopus 로고    scopus 로고
    • Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
    • Oda, E., Ohki, R., Murasawa, H., Nemoto, J., Shibue, T., et al. (2000) Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science 288, 1053-1058.
    • (2000) Science , vol.288 , pp. 1053-1058
    • Oda, E.1    Ohki, R.2    Murasawa, H.3    Nemoto, J.4    Shibue, T.5
  • 41
    • 0029003501 scopus 로고
    • Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression
    • Owen-Schaub, L. B., Zhang, W., Cusack, J. C., Angelo, L. S., Santee, S. M., et al. (1995) Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression. Mol. Cell. Biol. 15, 3032-3040.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3032-3040
    • Owen-Schaub, L.B.1    Zhang, W.2    Cusack, J.C.3    Angelo, L.S.4    Santee, S.M.5
  • 43
    • 0030748598 scopus 로고    scopus 로고
    • Differential activation of p53 targets in cells treated with ultraviolet radiation that undergo both apoptosis and growth arrest
    • Reinke, V. and Lozano, G. (1997) Differential activation of p53 targets in cells treated with ultraviolet radiation that undergo both apoptosis and growth arrest. Radiat. Res. 148, 115-122.
    • (1997) Radiat. Res. , vol.148 , pp. 115-122
    • Reinke, V.1    Lozano, G.2
  • 44
    • 3442899943 scopus 로고    scopus 로고
    • Intracellular delivery of p53 fused to the basic domain of HIV-Tat
    • Ryu, J., Lee, H. J., Kim, K. A., Lee, J. Y., Lee, K. S., et al. (2004) Intracellular delivery of p53 fused to the basic domain of HIV-Tat. Mol. Cells 17, 353-359.
    • (2004) Mol. Cells , vol.17 , pp. 353-359
    • Ryu, J.1    Lee, H.J.2    Kim, K.A.3    Lee, J.Y.4    Lee, K.S.5
  • 45
    • 0032530486 scopus 로고    scopus 로고
    • DNA damage activates p53 through a phosphorylation-acetylation cascade
    • Sakaguchi, K., Herrera, J. E., Saito, S., Miki, T., Bustin, M., et al. (1998) DNA damage activates p53 through a phosphorylation-acetylation cascade. Genes Dev. 12, 2831-2841.
    • (1998) Genes Dev. , vol.12 , pp. 2831-2841
    • Sakaguchi, K.1    Herrera, J.E.2    Saito, S.3    Miki, T.4    Bustin, M.5
  • 46
    • 0033135756 scopus 로고    scopus 로고
    • Poly(ADP-ribosyl)ation of p53 during apoptosis in human osteosarcoma cells
    • Simbulan-Rosenthal, C. M., Rosenthal, D. S., Luo, R., and Smulson, M. E. (1999) Poly(ADP-ribosyl)ation of p53 during apoptosis in human osteosarcoma cells. Cancer Res. 59, 2190-2194.
    • (1999) Cancer Res. , vol.59 , pp. 2190-2194
    • Simbulan-Rosenthal, C.M.1    Rosenthal, D.S.2    Luo, R.3    Smulson, M.E.4
  • 47
    • 0344418424 scopus 로고    scopus 로고
    • Overexpression of human poly(ADP-ribose) polymerase in transfected hamster cells leads to increased poly(ADP-ribosyl)ation and cellular sensitization to gamma irradiation
    • Van Gool, L., Meyer, R., Tobiasch, E., Cziepluch, C., Jauniaux, J. C., et al. (1997) Overexpression of human poly(ADP-ribose) polymerase in transfected hamster cells leads to increased poly(ADP-ribosyl)ation and cellular sensitization to gamma irradiation. Eur. J. Biochem. 244, 15-20.
    • (1997) Eur. J. Biochem. , vol.244 , pp. 15-20
    • Van Gool, L.1    Meyer, R.2    Tobiasch, E.3    Cziepluch, C.4    Jauniaux, J.C.5
  • 48
    • 0030984490 scopus 로고    scopus 로고
    • PARP is important for genomic stability but dispensable in apoptosis
    • Wang, Z. Q., Stingl, L., Morrison, C., Jantsch, M., Los, M., et al. (1997) PARP is important for genomic stability but dispensable in apoptosis. Genes Dev. 11, 2347-2358.
    • (1997) Genes Dev. , vol.11 , pp. 2347-2358
    • Wang, Z.Q.1    Stingl, L.2    Morrison, C.3    Jantsch, M.4    Los, M.5
  • 49
    • 0032919454 scopus 로고    scopus 로고
    • Reduced stability of regularly spliced but not alternatively spliced p53 protein in PARP-deficient mouse fibroblasts
    • Wesierska-Gadek, J., Wang, Z. Q., and Schmid, G. (1999) Reduced stability of regularly spliced but not alternatively spliced p53 protein in PARP-deficient mouse fibroblasts. Cancer Res. 59, 28-34.
    • (1999) Cancer Res. , vol.59 , pp. 28-34
    • Wesierska-Gadek, J.1    Wang, Z.Q.2    Schmid, G.3
  • 50
    • 0033855685 scopus 로고    scopus 로고
    • Differential susceptibility of normal and PARP knock-out mouse fibroblasts to proteasome inhibitors
    • Wesierska-Gadek, J., Bohrn, E., Herceg, Z., Wang, Z. Q., and Wurzer, G. (2000) Differential susceptibility of normal and PARP knock-out mouse fibroblasts to proteasome inhibitors. J. Cell. Biochem. 78, 681-696.
    • (2000) J. Cell. Biochem. , vol.78 , pp. 681-696
    • Wesierska-Gadek, J.1    Bohrn, E.2    Herceg, Z.3    Wang, Z.Q.4    Wurzer, G.5
  • 51
    • 0034656243 scopus 로고    scopus 로고
    • Analysis of p53-regulated gene expression patterns using oligonucleotide arrays
    • Zhao, R., Gish, K., Murphy, M., Yin, Y., Notterman, D., et al. (2000) Analysis of p53-regulated gene expression patterns using oligonucleotide arrays. Genes Dev. 14, 981-993.
    • (2000) Genes Dev. , vol.14 , pp. 981-993
    • Zhao, R.1    Gish, K.2    Murphy, M.3    Yin, Y.4    Notterman, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.