-
1
-
-
0021666528
-
-
Osteoporosis. National Institutes of Health Consensus Development Conference Statement. Natl Inst Health Consens Dev Conf Consens Statement 1984;5:6
-
Osteoporosis. National Institutes of Health Consensus Development Conference Statement. Natl Inst Health Consens Dev Conf Consens Statement 1984;5:6
-
-
-
-
2
-
-
0026670254
-
Perspective. How many women have osteoporosis?
-
Melton LJ, 3rd, Chrischilles EA, Cooper C, Lane AW and Riggs BL. Perspective. How many women have osteoporosis? J Bone Miner Res 1992;7:1005-1010.
-
(1992)
J Bone Miner Res
, vol.7
, pp. 1005-1010
-
-
Melton 3rd, L.J.1
Chrischilles, E.A.2
Cooper, C.3
Lane, A.W.4
Riggs, B.L.5
-
3
-
-
42549168550
-
Gut, inflammation and osteoporosis: Basic and clinical concepts
-
Tilg H, Moschen AR, Kaser A, Pines A and Dotan I. Gut, inflammation and osteoporosis: basic and clinical concepts. Gut 2008;57: 684-694.
-
(2008)
Gut
, vol.57
, pp. 684-694
-
-
Tilg, H.1
Moschen, A.R.2
Kaser, A.3
Pines, A.4
Dotan, I.5
-
4
-
-
10044265238
-
Characterization of adhesion and differentiation markers of osteogenic marrow stromal cells
-
Marom R, Shur I, Solomon R and Benayahu D. Characterization of adhesion and differentiation markers of osteogenic marrow stromal cells. J Cell Physiol 2005;202: 41-48.
-
(2005)
J Cell Physiol
, vol.202
, pp. 41-48
-
-
Marom, R.1
Shur, I.2
Solomon, R.3
Benayahu, D.4
-
5
-
-
0025049142
-
Origin of osteoclasts: Mature monocytes and macrophages are capable of differentiating into osteoclasts under a suitable microenvironment prepared by bone marrow-derived stromal cells
-
Udagawa N, Takahashi N, Akatsu T, Tanaka H, Sasaki T, Nishihara T, Koga T, Martin TJ and Suda T. Origin of osteoclasts: mature monocytes and macrophages are capable of differentiating into osteoclasts under a suitable microenvironment prepared by bone marrow-derived stromal cells. Proc Natl Acad Sci USA 1990;87:7260-7264.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 7260-7264
-
-
Udagawa, N.1
Takahashi, N.2
Akatsu, T.3
Tanaka, H.4
Sasaki, T.5
Nishihara, T.6
Koga, T.7
Martin, T.J.8
Suda, T.9
-
6
-
-
0025294673
-
Identification of committed mononuclear precursors for osteoclast-like cells formed in long term human marrow cultures
-
Kurihara N, Chenu C, Miller M, Civin C and Roodman GD. Identification of committed mononuclear precursors for osteoclast-like cells formed in long term human marrow cultures. Endocrinology 1990;126: 2733-2741.
-
(1990)
Endocrinology
, vol.126
, pp. 2733-2741
-
-
Kurihara, N.1
Chenu, C.2
Miller, M.3
Civin, C.4
Roodman, G.D.5
-
7
-
-
0025903876
-
Essential role of macrophage colony-stimulating factor in the osteoclast differentiation supported by stromal cells
-
Kodama H, Nose M, Niida S and Yamasaki A. Essential role of macrophage colony-stimulating factor in the osteoclast differentiation supported by stromal cells. J Exp Med 1991;173:1291-1294.
-
(1991)
J Exp Med
, vol.173
, pp. 1291-1294
-
-
Kodama, H.1
Nose, M.2
Niida, S.3
Yamasaki, A.4
-
8
-
-
29644433627
-
Identification of multiple osteoclast precursor populations in murine bone marrow
-
Jacquin C, Gran DE, Lee SK, Lorenzo JA and Aguila HL. Identification of multiple osteoclast precursor populations in murine bone marrow. J Bone Miner Res 2006;21: 67-77.
-
(2006)
J Bone Miner Res
, vol.21
, pp. 67-77
-
-
Jacquin, C.1
Gran, D.E.2
Lee, S.K.3
Lorenzo, J.A.4
Aguila, H.L.5
-
9
-
-
10044225587
-
Postmenopausal osteoporosis, T cells, and immune dysfunction
-
Teitelbaum SL. Postmenopausal osteoporosis, T cells, and immune dysfunction. Proc Natl Acad Sci USA 2004; 101:16711-16712.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 16711-16712
-
-
Teitelbaum, S.L.1
-
10
-
-
0037388342
-
T cells regulate the expression of matrix metalloproteinase in human osteoblasts via a dual mitogen-activated protein kinase mechanism
-
Rifas L and Arackal S. T cells regulate the expression of matrix metalloproteinase in human osteoblasts via a dual mitogen-activated protein kinase mechanism. Arthritis Rheum 2003;48:993-1001.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 993-1001
-
-
Rifas, L.1
Arackal, S.2
-
11
-
-
9244252016
-
The molecular triad OPG/RANK/RANKL: Involvement in the orchestration of pathophysiological bone remodeling
-
Theoleyre S, Wittrant Y, Tat SK, Fortun Y, Redini F and Heymann D. The molecular triad OPG/RANK/RANKL: involvement in the orchestration of pathophysiological bone remodeling. Cytokine Growth Factor Rev 2004;15:457-475.
-
(2004)
Cytokine Growth Factor Rev
, vol.15
, pp. 457-475
-
-
Theoleyre, S.1
Wittrant, Y.2
Tat, S.K.3
Fortun, Y.4
Redini, F.5
Heymann, D.6
-
12
-
-
33646396235
-
Estrogen deficiency and bone loss: An inflammatory tale
-
Weitzmann MN and Pacifici R. Estrogen deficiency and bone loss: an inflammatory tale. J Clin Invest 2006;116:1186-1194.
-
(2006)
J Clin Invest
, vol.116
, pp. 1186-1194
-
-
Weitzmann, M.N.1
Pacifici, R.2
-
13
-
-
0142091199
-
T-cells mediate an inhibitory effect of interleukin-4 on osteoclastogenesis
-
Mirosavljevic D, Quinn JM, Elliott J, Horwood NJ, Martin TJ and Gillespie MT. T-cells mediate an inhibitory effect of interleukin-4 on osteoclastogenesis. J Bone Miner Res 2003;18:984-993.
-
(2003)
J Bone Miner Res
, vol.18
, pp. 984-993
-
-
Mirosavljevic, D.1
Quinn, J.M.2
Elliott, J.3
Horwood, N.J.4
Martin, T.J.5
Gillespie, M.T.6
-
14
-
-
0034735773
-
T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-gamma
-
Takayanagi H, Ogasawara K, Hida S, Chiba T, Murata S, Sato K, Takaoka A, Yokochi T, Oda H, Tanaka K, Nakamura K and Taniguchi T. T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-gamma. Nature 2000;408:600-605.
-
(2000)
Nature
, vol.408
, pp. 600-605
-
-
Takayanagi, H.1
Ogasawara, K.2
Hida, S.3
Chiba, T.4
Murata, S.5
Sato, K.6
Takaoka, A.7
Yokochi, T.8
Oda, H.9
Tanaka, K.10
Nakamura, K.11
Taniguchi, T.12
-
15
-
-
20644461911
-
The bone marrow: A nest for migratory memory T cells
-
Di Rosa F and Pabst R. The bone marrow: a nest for migratory memory T cells. Trends Immunol 2005;26:360-366.
-
(2005)
Trends Immunol
, vol.26
, pp. 360-366
-
-
Di Rosa, F.1
Pabst, R.2
-
16
-
-
34548856484
-
Bone marrow CD8 cells down-modulate membrane IL-7Ralpha expression and exhibit increased STAT-5 and p38 MAPK phosphorylation in the organ environment
-
Cassese G, Parretta E, Pisapia L, Santoni A, Guardiola J and Di Rosa F. Bone marrow CD8 cells down-modulate membrane IL-7Ralpha expression and exhibit increased STAT-5 and p38 MAPK phosphorylation in the organ environment. Blood 2007;110:1960-1969.
-
(2007)
Blood
, vol.110
, pp. 1960-1969
-
-
Cassese, G.1
Parretta, E.2
Pisapia, L.3
Santoni, A.4
Guardiola, J.5
Di Rosa, F.6
-
17
-
-
47249143671
-
Kinetics of in vivo proliferation and death of memory and naive CD8 T cells: Parameter estimation based on 5-bromo-2′-deoxyuridine incorporation in spleen, lymph nodes, and bone marrow
-
Parretta E, Cassese G, Santoni A, Guardiola J, Vecchio A and Di Rosa F. Kinetics of in vivo proliferation and death of memory and naive CD8 T cells: parameter estimation based on 5-bromo-2′-deoxyuridine incorporation in spleen, lymph nodes, and bone marrow. J Immunol 2008;180:7230-7239.
-
(2008)
J Immunol
, vol.180
, pp. 7230-7239
-
-
Parretta, E.1
Cassese, G.2
Santoni, A.3
Guardiola, J.4
Vecchio, A.5
Di Rosa, F.6
-
18
-
-
0141796315
-
Bone marrow as a priming site for T-cell responses to blood-borne antigen
-
Feuerer M, Beckhove P, Garbi N, Mahnke Y, Limmer A, Hommel M, Hammerling GJ, Kyewski B, Hamann A, Umansky V and Schirrmacher V. Bone marrow as a priming site for T-cell responses to blood-borne antigen. Nat Med 2003;9:1151-1157.
-
(2003)
Nat Med
, vol.9
, pp. 1151-1157
-
-
Feuerer, M.1
Beckhove, P.2
Garbi, N.3
Mahnke, Y.4
Limmer, A.5
Hommel, M.6
Hammerling, G.J.7
Kyewski, B.8
Hamann, A.9
Umansky, V.10
Schirrmacher, V.11
-
19
-
-
13844272211
-
Bone marrow is a major reservoir and site of recruitment for central memory CD8+ T cells
-
Mazo IB, Honczarenko M, Leung H, Cavanagh LL, Bonasio R, Weninger W, Engelke K, Xia L, McEver RP, Koni PA, Silberstein LE and von Andrian UH. Bone marrow is a major reservoir and site of recruitment for central memory CD8+ T cells. Immunity 2005;22:259-270.
-
(2005)
Immunity
, vol.22
, pp. 259-270
-
-
Mazo, I.B.1
Honczarenko, M.2
Leung, H.3
Cavanagh, L.L.4
Bonasio, R.5
Weninger, W.6
Engelke, K.7
Xia, L.8
McEver, R.P.9
Koni, P.A.10
Silberstein, L.E.11
von Andrian, U.H.12
-
20
-
-
60249093936
-
Bone marrow-based homeostatic proliferation of mature T cells in nonhuman primates: Implications for AIDS pathogenesis
-
Paiardini M, Cervasi B, Engram JC, Gordon SN, Klatt NR, Muthukumar A, Else J, Mittler RS, Staprans SI, Sodora DL and Silvestri G. Bone marrow-based homeostatic proliferation of mature T cells in nonhuman primates: implications for AIDS pathogenesis. Blood 2009;113:612-621.
-
(2009)
Blood
, vol.113
, pp. 612-621
-
-
Paiardini, M.1
Cervasi, B.2
Engram, J.C.3
Gordon, S.N.4
Klatt, N.R.5
Muthukumar, A.6
Else, J.7
Mittler, R.S.8
Staprans, S.I.9
Sodora, D.L.10
Silvestri, G.11
-
21
-
-
0033581952
-
Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand
-
Kong YY, Feige U, Sarosi I, Bolon B, Tafuri A, Morony S, Capparelli C, Li J, Elliott R, McCabe S, Wong T, Campagnuolo G, Moran E, Bogoch ER, Van G, Nguyen LT, Ohashi PS, Lacey DL, Fish E, Boyle WJ and Penninger JM. Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand. Nature 1999;402: 304-309.
-
(1999)
Nature
, vol.402
, pp. 304-309
-
-
Kong, Y.Y.1
Feige, U.2
Sarosi, I.3
Bolon, B.4
Tafuri, A.5
Morony, S.6
Capparelli, C.7
Li, J.8
Elliott, R.9
McCabe, S.10
Wong, T.11
Campagnuolo, G.12
Moran, E.13
Bogoch, E.R.14
Van, G.15
Nguyen, L.T.16
Ohashi, P.S.17
Lacey, D.L.18
Fish, E.19
Boyle, W.J.20
Penninger, J.M.21
more..
-
22
-
-
0033708837
-
Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-alpha
-
Cenci S, Weitzmann MN, Roggia C, Namba N, Novack D, Woodring J and Pacifici R. Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-alpha. J Clin Invest 2000;106:1229-1237.
-
(2000)
J Clin Invest
, vol.106
, pp. 1229-1237
-
-
Cenci, S.1
Weitzmann, M.N.2
Roggia, C.3
Namba, N.4
Novack, D.5
Woodring, J.6
Pacifici, R.7
-
23
-
-
0035923727
-
Up-regulation of TNF-producing T cells in the bone marrow: A key mechanism by which estrogen deficiency induces bone loss in vivo
-
Roggia C, Gao Y, Cenci S, Weitzmann MN, Toraldo G, Isaia G and Pacifici R. Up-regulation of TNF-producing T cells in the bone marrow: a key mechanism by which estrogen deficiency induces bone loss in vivo. Proc Natl Acad Sci USA 2001; 98: 13960-13965.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 13960-13965
-
-
Roggia, C.1
Gao, Y.2
Cenci, S.3
Weitzmann, M.N.4
Toraldo, G.5
Isaia, G.6
Pacifici, R.7
-
24
-
-
0041836267
-
Estrogen deficiency induces bone loss by increasing T cell proliferation and lifespan through IFN-gamma-induced class II transactivator
-
Cenci S, Toraldo G, Weitzmann MN, Roggia C, Gao Y, Qian WP, Sierra O and Pacifici R. Estrogen deficiency induces bone loss by increasing T cell proliferation and lifespan through IFN-gamma-induced class II transactivator. Proc Natl Acad Sci USA 2003; 100:10405-10410.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 10405-10410
-
-
Cenci, S.1
Toraldo, G.2
Weitzmann, M.N.3
Roggia, C.4
Gao, Y.5
Qian, W.P.6
Sierra, O.7
Pacifici, R.8
-
25
-
-
44949083462
-
Estrogen deficiency increases osteoclastogenesis up-regulating T cells activity: A key mechanism in osteoporosis
-
D'Amelio P, Grimaldi A, Di Bella S, Brianza SZ, Cristofaro MA, Tamone C, Giribaldi G, Ulliers D, Pescarmona GP and Isaia G. Estrogen deficiency increases osteoclastogenesis up-regulating T cells activity: a key mechanism in osteoporosis. Bone 2008; 43: 92-100.
-
(2008)
Bone
, vol.43
, pp. 92-100
-
-
D'Amelio, P.1
Grimaldi, A.2
Di Bella, S.3
Brianza, S.Z.4
Cristofaro, M.A.5
Tamone, C.6
Giribaldi, G.7
Ulliers, D.8
Pescarmona, G.P.9
Isaia, G.10
-
26
-
-
33751521013
-
Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction
-
Sato K, Suematsu A, Okamoto K, Yamaguchi A, Morishita Y, Kadono Y, Tanaka S, Kodama T, Akira S, Iwakura Y, Cua DJ and Takayanagi H. Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction. J Exp Med 2006;203:2673-2682.
-
(2006)
J Exp Med
, vol.203
, pp. 2673-2682
-
-
Sato, K.1
Suematsu, A.2
Okamoto, K.3
Yamaguchi, A.4
Morishita, Y.5
Kadono, Y.6
Tanaka, S.7
Kodama, T.8
Akira, S.9
Iwakura, Y.10
Cua, D.J.11
Takayanagi, H.12
-
27
-
-
0034947297
-
Osteoclastogenesis is enhanced by activated B cells but suppressed by activated CD8(+) T cells
-
Choi Y, Woo KM, Ko SH, Lee YJ, Park SJ, Kim HM and Kwon BS. Osteoclastogenesis is enhanced by activated B cells but suppressed by activated CD8(+) T cells. Eur J Immunol 2001;31:2179-2188.
-
(2001)
Eur J Immunol
, vol.31
, pp. 2179-2188
-
-
Choi, Y.1
Woo, K.M.2
Ko, S.H.3
Lee, Y.J.4
Park, S.J.5
Kim, H.M.6
Kwon, B.S.7
-
28
-
-
0029938143
-
A role for CD8+ T lymphocytes in osteoclast differentiation in vitro
-
John V, Hock JM, Short LL, Glasebrook AL and Galvin RJ. A role for CD8+ T lymphocytes in osteoclast differentiation in vitro. Endocrinology 1996;137:2457-2463.
-
(1996)
Endocrinology
, vol.137
, pp. 2457-2463
-
-
John, V.1
Hock, J.M.2
Short, L.L.3
Glasebrook, A.L.4
Galvin, R.J.5
-
29
-
-
0033104614
-
TRANCE, a TNF family member, is differentially expressed on T cell subsets and induces cytokine production in dendritic cells
-
Josien R, Wong BR, Li HL, Steinman RM and Choi Y. TRANCE, a TNF family member, is differentially expressed on T cell subsets and induces cytokine production in dendritic cells. J Immunol 1999;162:2562-2568.
-
(1999)
J Immunol
, vol.162
, pp. 2562-2568
-
-
Josien, R.1
Wong, B.R.2
Li, H.L.3
Steinman, R.M.4
Choi, Y.5
-
30
-
-
0034667933
-
Depletion of CD4 and CD8 T lymphocytes in mice in vivo enhances 1,25-dihydroxyvitamin D3-stimulated osteoclast-like cell formation in vitro by a mechanism that is dependent on prostaglandin synthesis
-
Grcevic D, Lee SK, Marusic A and Lorenzo JA. Depletion of CD4 and CD8 T lymphocytes in mice in vivo enhances 1,25-dihydroxyvitamin D3-stimulated osteoclast-like cell formation in vitro by a mechanism that is dependent on prostaglandin synthesis. J Immunol 2000; 165:4231-4238.
-
(2000)
J Immunol
, vol.165
, pp. 4231-4238
-
-
Grcevic, D.1
Lee, S.K.2
Marusic, A.3
Lorenzo, J.A.4
-
31
-
-
34247323904
-
B cells and T cells are critical for the preservation of bone homeostasis and attainment of peak bone mass in vivo
-
Li Y, Toraldo G, Li A, Yang X, Zhang H, Qian WP and Weitzmann MN. B cells and T cells are critical for the preservation of bone homeostasis and attainment of peak bone mass in vivo. Blood 2007; 109:3839-3848.
-
(2007)
Blood
, vol.109
, pp. 3839-3848
-
-
Li, Y.1
Toraldo, G.2
Li, A.3
Yang, X.4
Zhang, H.5
Qian, W.P.6
Weitzmann, M.N.7
-
32
-
-
4344715205
-
Effects of activated T cells on osteoclastogenesis depend on how they are activated
-
Wyzga N, Varghese S, Wikel S, Canalis E and Sylvester FA. Effects of activated T cells on osteoclastogenesis depend on how they are activated. Bone 2004;35:614-620.
-
(2004)
Bone
, vol.35
, pp. 614-620
-
-
Wyzga, N.1
Varghese, S.2
Wikel, S.3
Canalis, E.4
Sylvester, F.A.5
-
33
-
-
33947583822
-
Osteoimmunology: Shared mechanisms and crosstalk between the immune and bone systems
-
Takayanagi H. Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems. Nat Rev Immunol 2007;7:292-304.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 292-304
-
-
Takayanagi, H.1
-
34
-
-
0034284970
-
Bone resorption by osteoclasts
-
Teitelbaum SL. Bone resorption by osteoclasts. Science 2000;289:1504-1508.
-
(2000)
Science
, vol.289
, pp. 1504-1508
-
-
Teitelbaum, S.L.1
-
36
-
-
56549098575
-
RANK/RANKL: Regulators of immune responses and bone physiology
-
Leibbrandt A and Penninger JM. RANK/RANKL: regulators of immune responses and bone physiology. Ann N Y Acad Sci 2008;1143:123-150.
-
(2008)
Ann N Y Acad Sci
, vol.1143
, pp. 123-150
-
-
Leibbrandt, A.1
Penninger, J.M.2
-
37
-
-
15444381042
-
RANK-mediated amplification of TRAF6 signaling leads to NFATc1 induction during osteoclastogenesis
-
Gohda J, Akiyama T, Koga T, Takayanagi H, Tanaka S and Inoue J. RANK-mediated amplification of TRAF6 signaling leads to NFATc1 induction during osteoclastogenesis. EMBO J 2005;24:790-799.
-
(2005)
EMBO J
, vol.24
, pp. 790-799
-
-
Gohda, J.1
Akiyama, T.2
Koga, T.3
Takayanagi, H.4
Tanaka, S.5
Inoue, J.6
-
38
-
-
33845539490
-
Regulation of osteoclast differentiation and function by the CaMK-CREB pathway
-
Sato K, Suematsu A, Nakashima T, Takemoto-Kimura S, Aoki K, Morishita Y, Asahara H, Ohya K, Yamaguchi A, Takai T, Kodama T, Chatila TA, Bito H and Takayanagi H. Regulation of osteoclast differentiation and function by the CaMK-CREB pathway. Nat Med 2006;12:1410-1416.
-
(2006)
Nat Med
, vol.12
, pp. 1410-1416
-
-
Sato, K.1
Suematsu, A.2
Nakashima, T.3
Takemoto-Kimura, S.4
Aoki, K.5
Morishita, Y.6
Asahara, H.7
Ohya, K.8
Yamaguchi, A.9
Takai, T.10
Kodama, T.11
Chatila, T.A.12
Bito, H.13
Takayanagi, H.14
-
39
-
-
55849088412
-
NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism
-
Aliprantis AO, Ueki Y, Sulyanto R, Park A, Sigrist KS, Sharma SM, Ostrowski MC, Olsen BR and Glimcher LH. NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism. J Clin Invest 2008;118:3775-3789.
-
(2008)
J Clin Invest
, vol.118
, pp. 3775-3789
-
-
Aliprantis, A.O.1
Ueki, Y.2
Sulyanto, R.3
Park, A.4
Sigrist, K.S.5
Sharma, S.M.6
Ostrowski, M.C.7
Olsen, B.R.8
Glimcher, L.H.9
-
40
-
-
65249180600
-
Selective inhibition of RANK blocks osteoclast maturation and function and prevents bone loss in mice
-
Kim H, Choi HK, Shin JH, Kim KH, Huh JY, Lee SA, Ko CY, Kim HS, Shin HI, Lee HJ, Jeong D, Kim N, Choi Y and Lee SY. Selective inhibition of RANK blocks osteoclast maturation and function and prevents bone loss in mice. J Clin Invest 2009;119: 813-825.
-
(2009)
J Clin Invest
, vol.119
, pp. 813-825
-
-
Kim, H.1
Choi, H.K.2
Shin, J.H.3
Kim, K.H.4
Huh, J.Y.5
Lee, S.A.6
Ko, C.Y.7
Kim, H.S.8
Shin, H.I.9
Lee, H.J.10
Jeong, D.11
Kim, N.12
Choi, Y.13
Lee, S.Y.14
-
41
-
-
67649811207
-
Bidirectional signaling through ephrinA2-EphA2 enhances osteoclastogenesis and suppresses osteoblastogenesis
-
Epub ahead of print
-
Irie N, Takada Y, Watanabe Y, Matsuzaki Y, Naruse C, Asano M, Iwakura Y, Suda T and Matsuo K. Bidirectional signaling through ephrinA2-EphA2 enhances osteoclastogenesis and suppresses osteoblastogenesis. J Biol Chem 2009 [Epub ahead of print]
-
(2009)
J Biol Chem
-
-
Irie, N.1
Takada, Y.2
Watanabe, Y.3
Matsuzaki, Y.4
Naruse, C.5
Asano, M.6
Iwakura, Y.7
Suda, T.8
Matsuo, K.9
-
42
-
-
43049124129
-
Deubiquitinating enzyme CYLD negatively regulates RANK signaling and osteoclastogenesis in mice
-
Jin W, Chang M, Paul EM, Babu G, Lee AJ, Reiley W, Wright A, Zhang M, You J and Sun SC. Deubiquitinating enzyme CYLD negatively regulates RANK signaling and osteoclastogenesis in mice. J Clin Invest 2008;118:1858-1866.
-
(2008)
J Clin Invest
, vol.118
, pp. 1858-1866
-
-
Jin, W.1
Chang, M.2
Paul, E.M.3
Babu, G.4
Lee, A.J.5
Reiley, W.6
Wright, A.7
Zhang, M.8
You, J.9
Sun, S.C.10
-
43
-
-
60549103884
-
The Src family kinase, Lyn, suppresses osteoclastogenesis in vitro and in vivo
-
Kim HJ, Zhang K, Zhang L, Ross FP, Teitelbaum SL and Faccio R. The Src family kinase, Lyn, suppresses osteoclastogenesis in vitro and in vivo. Proc Natl Acad Sci USA 2009;106:2325-2330.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 2325-2330
-
-
Kim, H.J.1
Zhang, K.2
Zhang, L.3
Ross, F.P.4
Teitelbaum, S.L.5
Faccio, R.6
-
44
-
-
45749124735
-
RelA/ p65 promotes osteoclast differentiation by blocking a RANKL-induced apoptotic JNK pathway in mice
-
Vaira S, Alhawagri M, Anwisye I, Kitaura H, Faccio R and Novack DV. RelA/ p65 promotes osteoclast differentiation by blocking a RANKL-induced apoptotic JNK pathway in mice. J Clin Invest 2008;118:2088-2097.
-
(2008)
J Clin Invest
, vol.118
, pp. 2088-2097
-
-
Vaira, S.1
Alhawagri, M.2
Anwisye, I.3
Kitaura, H.4
Faccio, R.5
Novack, D.V.6
-
45
-
-
0036584028
-
Development of anti-TNF therapy for rheumatoid arthritis
-
Feldmann M. Development of anti-TNF therapy for rheumatoid arthritis. Nat Rev Immunol 2002;2:364-371.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 364-371
-
-
Feldmann, M.1
-
46
-
-
17244364098
-
Evidence of radiographic benefit of treatment with infliximab plus methotrexate in rheumatoid arthritis patients who had no clinical improvement: A detailed subanalysis of data from the anti-tumor necrosis factor trial in rheumatoid arthritis with concomitant therapy study
-
Smolen JS, Han C, Bala M, Maini RN, Kalden JR, van der Heijde D, Breedveld FC, Furst DE and Lipsky PE. Evidence of radiographic benefit of treatment with infliximab plus methotrexate in rheumatoid arthritis patients who had no clinical improvement: a detailed subanalysis of data from the anti-tumor necrosis factor trial in rheumatoid arthritis with concomitant therapy study. Arthritis Rheum 2005;52:1020-1030.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 1020-1030
-
-
Smolen, J.S.1
Han, C.2
Bala, M.3
Maini, R.N.4
Kalden, J.R.5
van der Heijde, D.6
Breedveld, F.C.7
Furst, D.E.8
Lipsky, P.E.9
-
47
-
-
14944371405
-
-
Wei S, Kitaura H, Zhou P, Ross FP and Teitelbaum SL. IL-1 mediates TNF-induced osteoclastogenesis. J Clin Invest 2005;115: 282-290.
-
Wei S, Kitaura H, Zhou P, Ross FP and Teitelbaum SL. IL-1 mediates TNF-induced osteoclastogenesis. J Clin Invest 2005;115: 282-290.
-
-
-
-
48
-
-
31044436261
-
M-CSF mediates TNF-induced inflammatory osteolysis
-
Kitaura H, Zhou P, Kim HJ, Novack DV, Ross FP and Teitelbaum SL. M-CSF mediates TNF-induced inflammatory osteolysis. J Clin Invest 2005;115:3418-3427.
-
(2005)
J Clin Invest
, vol.115
, pp. 3418-3427
-
-
Kitaura, H.1
Zhou, P.2
Kim, H.J.3
Novack, D.V.4
Ross, F.P.5
Teitelbaum, S.L.6
-
49
-
-
34547470906
-
Pathological role of osteoclast costimulation in arthritis-induced bone loss
-
Ochi S, Shinohara M, Sato K, Gober HJ, Koga T, Kodama T, Takai T, Miyasaka N and Takayanagi H. Pathological role of osteoclast costimulation in arthritis-induced bone loss. Proc Natl Acad Sci USA 2007; 104: 11394-11399.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 11394-11399
-
-
Ochi, S.1
Shinohara, M.2
Sato, K.3
Gober, H.J.4
Koga, T.5
Kodama, T.6
Takai, T.7
Miyasaka, N.8
Takayanagi, H.9
-
50
-
-
39149116741
-
Macrophage-elicited osteoclastogenesis in response to bacterial stimulation requires Toll-like receptor 2-dependent tumor necrosis factor-alpha production
-
Ukai T, Yumoto H, Gibson FC, 3rd and Genco CA. Macrophage-elicited osteoclastogenesis in response to bacterial stimulation requires Toll-like receptor 2-dependent tumor necrosis factor-alpha production. Infect Immun 2008;76:812-819.
-
(2008)
Infect Immun
, vol.76
, pp. 812-819
-
-
Ukai, T.1
Yumoto, H.2
Gibson 3rd, F.C.3
Genco, C.A.4
-
51
-
-
33745199187
-
A TNF receptor loop peptide mimic blocks RANK ligand-induced signaling, bone resorption, and bone loss
-
Aoki K, Saito H, Itzstein C, Ishiguro M, Shibata T, Blanque R, Mian AH, Takahashi M, Suzuki Y, Yoshimatsu M, Yamaguchi A, Deprez P, Mollat P, Murali R, Ohya K, Horne WC and Baron R. A TNF receptor loop peptide mimic blocks RANK ligand-induced signaling, bone resorption, and bone loss. J Clin Invest 2006;116:1525-1534.
-
(2006)
J Clin Invest
, vol.116
, pp. 1525-1534
-
-
Aoki, K.1
Saito, H.2
Itzstein, C.3
Ishiguro, M.4
Shibata, T.5
Blanque, R.6
Mian, A.H.7
Takahashi, M.8
Suzuki, Y.9
Yoshimatsu, M.10
Yamaguchi, A.11
Deprez, P.12
Mollat, P.13
Murali, R.14
Ohya, K.15
Horne, W.C.16
Baron, R.17
-
52
-
-
45149127782
-
Osteoimmunology: Interactions of the bone and immune system
-
Lorenzo J, Horowitz M and Choi Y. Osteoimmunology: interactions of the bone and immune system. Endocr Rev 2008; 29: 403-440.
-
(2008)
Endocr Rev
, vol.29
, pp. 403-440
-
-
Lorenzo, J.1
Horowitz, M.2
Choi, Y.3
-
53
-
-
0033912344
-
IFN-gamma enhances osteoclast generation in cultures of peripheral blood from osteopetrotic patients and normalizes superoxide production
-
Madyastha PR, Yang S, Ries WL and Key LL, Jr. IFN-gamma enhances osteoclast generation in cultures of peripheral blood from osteopetrotic patients and normalizes superoxide production. J Interferon Cytokine Res 2000;20:645-652.
-
(2000)
J Interferon Cytokine Res
, vol.20
, pp. 645-652
-
-
Madyastha, P.R.1
Yang, S.2
Ries, W.L.3
Key Jr., L.L.4
-
54
-
-
0142244577
-
Exposure to receptor-activator of NFkappaB ligand renders pre-osteoclasts resistant to IFN-gamma by inducing terminal differentiation
-
Huang W, O'Keefe RJ and Schwarz EM. Exposure to receptor-activator of NFkappaB ligand renders pre-osteoclasts resistant to IFN-gamma by inducing terminal differentiation. Arthritis Res Ther 2003;5: R49-59.
-
(2003)
Arthritis Res Ther
, vol.5
-
-
Huang, W.1
O'Keefe, R.J.2
Schwarz, E.M.3
-
55
-
-
27944457190
-
IFN-gamma-producing human T cells directly induce osteoclastogenesis from human monocytes via the expression of RANKL
-
Kotake S, Nanke Y, Mogi M, Kawamoto M, Furuya T, Yago T, Kobashigawa T, Togari A and Kamatani N. IFN-gamma-producing human T cells directly induce osteoclastogenesis from human monocytes via the expression of RANKL. Eur J Immunol 2005;35:3353-3363.
-
(2005)
Eur J Immunol
, vol.35
, pp. 3353-3363
-
-
Kotake, S.1
Nanke, Y.2
Mogi, M.3
Kawamoto, M.4
Furuya, T.5
Yago, T.6
Kobashigawa, T.7
Togari, A.8
Kamatani, N.9
-
56
-
-
0036652168
-
Interferon-gamma production changes in parallel with bacterial lipopolysaccharide induced bone resorption in mice: An immunohistometrical study
-
Moriyama H, Ukai T and Hara Y. Interferon-gamma production changes in parallel with bacterial lipopolysaccharide induced bone resorption in mice: an immunohistometrical study. Calcif Tissue Int 2002;71:53-58.
-
(2002)
Calcif Tissue Int
, vol.71
, pp. 53-58
-
-
Moriyama, H.1
Ukai, T.2
Hara, Y.3
-
57
-
-
19744362921
-
Gamma interferon positively modulates Actinobacillus actinomycetemcomitans-specific RANKL+ CD4+ Th-cell-mediated alveolar bone destruction in vivo
-
Teng YT, Mahamed D and Singh B. Gamma interferon positively modulates Actinobacillus actinomycetemcomitans-specific RANKL+ CD4+ Th-cell-mediated alveolar bone destruction in vivo. Infect Immun 2005;73:3453-3461.
-
(2005)
Infect Immun
, vol.73
, pp. 3453-3461
-
-
Teng, Y.T.1
Mahamed, D.2
Singh, B.3
-
58
-
-
33845981069
-
IFN-gamma stimulates osteoclast formation and bone loss in vivo via antigen-driven T cell activation
-
Gao Y, Grassi F, Ryan MR, Terauchi M, Page K, Yang X, Weitzmann MN and Pacifici R. IFN-gamma stimulates osteoclast formation and bone loss in vivo via antigen-driven T cell activation. J Clin Invest 2007;117:122-132.
-
(2007)
J Clin Invest
, vol.117
, pp. 122-132
-
-
Gao, Y.1
Grassi, F.2
Ryan, M.R.3
Terauchi, M.4
Page, K.5
Yang, X.6
Weitzmann, M.N.7
Pacifici, R.8
-
59
-
-
33646349199
-
Synovial membrane cytokine expression is predictive of joint damage progression in rheumatoid arthritis: A two-year prospective study (the DAMAGE study cohort)
-
Kirkham BW, Lassere MN, Edmonds JP, Juhasz KM, Bird PA, Lee CS, Shnier R and Portek IJ. Synovial membrane cytokine expression is predictive of joint damage progression in rheumatoid arthritis: a two-year prospective study (the DAMAGE study cohort). Arthritis Rheum 2006;54: 1122-1131.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 1122-1131
-
-
Kirkham, B.W.1
Lassere, M.N.2
Edmonds, J.P.3
Juhasz, K.M.4
Bird, P.A.5
Lee, C.S.6
Shnier, R.7
Portek, I.J.8
-
60
-
-
21244482587
-
Blocking of interleukin-17 during reactivation of experimental arthritis prevents joint inflammation and bone erosion by decreasing RANKL and interleukin-1
-
Koenders MI, Lubberts E, Oppers-Walgreen B, van den Bersselaar L, Helsen MM, Di Padova FE, Boots AM, Gram H, Joosten LA and van den Berg WB. Blocking of interleukin-17 during reactivation of experimental arthritis prevents joint inflammation and bone erosion by decreasing RANKL and interleukin-1. Am J Pathol 2005;167: 141-149.
-
(2005)
Am J Pathol
, vol.167
, pp. 141-149
-
-
Koenders, M.I.1
Lubberts, E.2
Oppers-Walgreen, B.3
van den Bersselaar, L.4
Helsen, M.M.5
Di Padova, F.E.6
Boots, A.M.7
Gram, H.8
Joosten, L.A.9
van den Berg, W.B.10
-
61
-
-
64149118092
-
Synergism between tumor necrosis factor alpha and interleukin-17 to induce IL-23 p19 expression in fibroblast-like synoviocytes
-
Goldberg M, Nadiv O, Luknar-Gabor N, Agar G, Beer Y and Katz Y. Synergism between tumor necrosis factor alpha and interleukin-17 to induce IL-23 p19 expression in fibroblast-like synoviocytes. Mol Immunol 2009;46:1854-1859.
-
(2009)
Mol Immunol
, vol.46
, pp. 1854-1859
-
-
Goldberg, M.1
Nadiv, O.2
Luknar-Gabor, N.3
Agar, G.4
Beer, Y.5
Katz, Y.6
-
62
-
-
0038623916
-
-
Nakae S, Saijo S, Horai R, Sudo K, Mori S and Iwakura Y. IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist. Proc Natl Acad Sci USA 2003; 100:5986-5990.
-
Nakae S, Saijo S, Horai R, Sudo K, Mori S and Iwakura Y. IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist. Proc Natl Acad Sci USA 2003; 100:5986-5990.
-
-
-
-
63
-
-
0344585384
-
Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice
-
Nakae S, Nambu A, Sudo K and Iwakura Y. Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice. J Immunol 2003;171:6173-6177.
-
(2003)
J Immunol
, vol.171
, pp. 6173-6177
-
-
Nakae, S.1
Nambu, A.2
Sudo, K.3
Iwakura, Y.4
-
64
-
-
23844545819
-
Requirement of IL-17 receptor signaling in radiation-resistant cells in the joint for full progression of destructive synovitis
-
Lubberts E, Schwarzenberger P, Huang W, Schurr JR, Peschon JJ, van den Berg WB and Kolls JK. Requirement of IL-17 receptor signaling in radiation-resistant cells in the joint for full progression of destructive synovitis. J Immunol 2005;175:3360-3368.
-
(2005)
J Immunol
, vol.175
, pp. 3360-3368
-
-
Lubberts, E.1
Schwarzenberger, P.2
Huang, W.3
Schurr, J.R.4
Peschon, J.J.5
van den Berg, W.B.6
Kolls, J.K.7
-
65
-
-
0032939156
-
Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium
-
Chabaud M, Durand JM, Buchs N, Fossiez F, Page G, Frappart L and Miossec P. Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium. Arthritis Rheum 1999; 42:963-970.
-
(1999)
Arthritis Rheum
, vol.42
, pp. 963-970
-
-
Chabaud, M.1
Durand, J.M.2
Buchs, N.3
Fossiez, F.4
Page, G.5
Frappart, L.6
Miossec, P.7
-
66
-
-
40549138745
-
Interleukin-17-producing T cells are enriched in the joints of children with arthritis, but have a reciprocal relationship to regulatory T cell numbers
-
Nistala K, Moncrieffe H, Newton KR, Varsani H, Hunter P and Wedderburn LR. Interleukin-17-producing T cells are enriched in the joints of children with arthritis, but have a reciprocal relationship to regulatory T cell numbers. Arthritis Rheum 2008;58: 875-887.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 875-887
-
-
Nistala, K.1
Moncrieffe, H.2
Newton, K.R.3
Varsani, H.4
Hunter, P.5
Wedderburn, L.R.6
-
67
-
-
33646490259
-
Interleukin-17 acts independently of TNF-alpha under arthritic conditions
-
Koenders MI, Lubberts E, van de Loo FA, Oppers-Walgreen B, van den Bersselaar L, Helsen MM, Kolls JK, Di Padova FE, Joosten LA and van den Berg WB. Interleukin-17 acts independently of TNF-alpha under arthritic conditions. J Immunol 2006; 176: 6262-6269.
-
(2006)
J Immunol
, vol.176
, pp. 6262-6269
-
-
Koenders, M.I.1
Lubberts, E.2
van de Loo, F.A.3
Oppers-Walgreen, B.4
van den Bersselaar, L.5
Helsen, M.M.6
Kolls, J.K.7
Di Padova, F.E.8
Joosten, L.A.9
van den Berg, W.B.10
-
68
-
-
65549165389
-
In vivo activated monocytes from the site of inflammation in humans specifically promote Th17 responses
-
Evans HG, Gullick NJ, Kelly S, Pitzalis C, Lord GM, Kirkham BW and Taams LS. In vivo activated monocytes from the site of inflammation in humans specifically promote Th17 responses. Proc Natl Acad Sci USA 2009;106:6232-6237.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 6232-6237
-
-
Evans, H.G.1
Gullick, N.J.2
Kelly, S.3
Pitzalis, C.4
Lord, G.M.5
Kirkham, B.W.6
Taams, L.S.7
-
69
-
-
58149166804
-
Blockade of tumor necrosis factor in collagen-induced arthritis reveals a novel immunoregulatory pathway for Th1 and Th17 cells
-
Notley CA, Inglis JJ, Alzabin S, McCann FE, McNamee KE and Williams RO. Blockade of tumor necrosis factor in collagen-induced arthritis reveals a novel immunoregulatory pathway for Th1 and Th17 cells. J Exp Med 2008;205:2491-2497.
-
(2008)
J Exp Med
, vol.205
, pp. 2491-2497
-
-
Notley, C.A.1
Inglis, J.J.2
Alzabin, S.3
McCann, F.E.4
McNamee, K.E.5
Williams, R.O.6
-
70
-
-
54449087291
-
Local BAFF gene silencing suppresses Th17-cell generation and ameliorates autoimmune arthritis
-
Lai Kwan Lam Q, King Hung Ko O, Zheng BJ and Lu L. Local BAFF gene silencing suppresses Th17-cell generation and ameliorates autoimmune arthritis. Proc Natl Acad Sci USA 2008;105:14993-14998.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 14993-14998
-
-
Lai1
Kwan Lam, Q.2
King3
Hung Ko, O.4
Zheng, B.J.5
Lu, L.6
-
71
-
-
33744779045
-
Estrogen regulation of immune cell bone interactions
-
Weitzmann MN and Pacifici R. Estrogen regulation of immune cell bone interactions. Ann N Y Acad Sci 2006; 1068: 256-274.
-
(2006)
Ann N Y Acad Sci
, vol.1068
, pp. 256-274
-
-
Weitzmann, M.N.1
Pacifici, R.2
-
72
-
-
49149107848
-
Osteoimmunology: Cytokines and the skeletal system
-
Lee SH, Kim TS, Choi Y and Lorenzo J. Osteoimmunology: cytokines and the skeletal system. BMB Rep 2008;41:495-510.
-
(2008)
BMB Rep
, vol.41
, pp. 495-510
-
-
Lee, S.H.1
Kim, T.S.2
Choi, Y.3
Lorenzo, J.4
|