Protein Serine/Threonine-Phosphatase 2C (PP2C)

Handbook of Cell Signaling: Volume 1-3

Volumn 1-3, Issue , 2003, Pages 637-640

  Tatebe, Hisashi ^a   Shiozaki, Kazuhiro ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 67649969130     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012124546-7/50468-X     Document Type: Chapter

References (29)

1. P. Cohen (1989) The structure and regulation of protein phosphatases. Annu. Rev. Biochem. 58 453-508.
2. D. Barford, A.K. Das and M.P. Egloff (1998) The structure and mechanism of protein phosphatases: insights into catalysis and regulation. Annu. Rev. Biophys. Biomol. Struct. 27 133-164.
3. C. Widmann, S. Gibson, M.B. Jarpe and G.L. Johnson (1999) Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human. Physiol. Rev. 79 143-180.
4. T. Maeda, S.M. Wurgler-Murphy and H. Saito (1994) A two-component system that regulates an osmosensing MAP kinase cascade in yeast. Nature 369 242-245.
5. K. Shiozaki and P. Russell (1994) Cellular function of protein phosphatase 2C in yeast. Cell. Mol. Biol. Res. 40 241-243.
6. K. Shiozaki and P. Russell (1995) Counteractive roles of protein phosphatase 2C and a MAP kinase kinase homolog in the osmoregulation of fission yeast. EMBO J. 14 492-502.
7. A.N. Nguyen and K. Shiozaki (1999) Heat shock-induced activation of stress MAP kinase is regulated by threonine- and tyrosine-specific phosphatases. Genes Dev. 13 1653-1663.
8. K. Shiozaki, M. Shiozaki and P. Russell (1998) Heat stress activates fission yeast Spc1/StyI MAPK by a MEKK-independent mechanism. Mol. Biol. Cell 9 1339-1349.
9. F. Gaits, K. Shiozaki and P. Russell (1997) Protein phosphatase 2C acts independently of stress-activated kinase cascade to regulate the stress response in fission yeast. J. Biol. Chem. 272 17873-17879.
10. J. Warmka, J. Hanneman, J. Lee, D. Amin and I. Ota (2001) Ptc1, a type 2C Ser/Thr phosphatase, inactivates the HOG pathway by dephosphorylating the mitogen-activated protein kinase hog1. Mol. Cell. Biol. 21 51-60.
11. M. Takekawa, T. Maeda and H. Saito (1998) Protein phosphatase 2Ca inhibits the human stress-responsive p38 and JNK MAPK pathways. EMBO J. 17 4744-4752.
12. M. Takekawa, et al. (2000) p53-inducible wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation. EMBO J. 19 6517-6526.
13. J. Choi, et al. (2002) Mice deficient for the wild-type p53-induced phosphatase gene (Wip1) exhibit defects in reproductive organs, immune function, and cell cycle control. Mol. Cell. Biol. 22 1094-1105.
14. I. Meskiene, et al. (1998) MP2C, a plant protein phosphatase 2C, functions as a negative regulator of mitogen-activated protein kinase pathways in yeast and plants. Proc. Natl. Acad. Sci. USA 95 1938-1943.
15. D.C. Gadsby and A.C. Nairn (1999) Control of CFTR channel gating by phosphorylation and nucleotide hydrolysis. Physiol. Rev. 79 S77-S107.
16. S.M. Travis, H.A. Berger and M.J. Welsh (1997) Protein phosphatase 2C dephosphorylates and inactivates cystic fibrosis transmembrane conductance regulator. Proc. Natl. Acad. Sci. USA 94 11055-11060.
17. T. Zhu, et al. (1999) Association of cystic fibrosis transmembrane conductance regulator and protein phosphatase 2C. J. Biol. Chem. 274 29102-29107.
18. D.A. Dahan, et al. (2001) Regulation of the CFTR channel by phosphorylation. Pflügers Arch. 443 S92-S96.
19. F. Gosti, et al. (1999) ABI1 protein phosphatase 2C is a negative regulator of abscisic acid signaling. Plant Cell 11 1897-1910.
20. S. Merlot, F. Gosti, D. Guerrier, A. Vavasseur and J. Giraudat (2001) The ABI1 and ABI2 protein phosphatases 2C act in a negative feedback regulatory loop of the abscisic acid signalling pathway. Plant J. 25 295-303.
21. J. Leung, S. Merlot and J. Giraudat (1997) The Arabidopsis ABSCISIC ACID-INSENSITIVE2 (ABI2) and ABI1 genes encode homologous protein phosphatases 2C involved in abscisic acid signal transduction. Plant Cell 9 759-771.
22. D. Pilgrim, A. McGregor, P. Jackle, T. Johnson and D. Hansen (1995) The C. elegans sex-determining gene fem-2 encodes a putative protein phosphatase. Mol. Cell. Biol. 6 1159-1171.
23. D. Hansen and D. Pilgrim (1998) Molecular evolution of a sex determination protein. FEM-2 (pp2c) in Caenorhabditis. Genetics 149 1353-1362.
24. I.D. Chin-Sang and A.M. Spence (1996) Caenorhabditis elegans sex-determining protein FEM-2 is a protein phosphatase that promotes male development and interacts directly with FEM-3. Genes Dev. 10 2314-2325.
25. K.M. Tan, S.L. Chan, K.O. Tan and V.C. Yu (2001) The Caenorhabditis elegans sex-determining protein FEM-2 and its human homologue, hFEM-2, are Ca2+/calmodulin-dependent protein kinase phosphatases that promote apoptosis. J. Biol. Chem. 276 44193-44202.
26. T. Kitani, et al. (1999) Molecular cloning of Ca2+/calmodulin-dependent protein kinase phosphatase. J. Biochem. (Tokyo) 125 1022-1028.
27. M. Hecker and U. Volker (2001) General stress response of Bacillus subtilis and other bacteria. Adv. Microbiol. Physiol. 44 35-91.
28. K. Vijay, M.S. Brody, E. Fredlund and C.W. Price (2000) A PP2C phosphatase containing a PAS domain is required to convey signals of energy stress to the sigmaB transcription factor of Bacillus subtilis. Mol. Microbiol. 35 180-188.
29. X. Yang, C.M. Kang, M.S. Brody and C.W. Price (1996) Opposing pairs of serine protein kinases and phosphatases transmit signals of environmental stress to activate a bacterial transcription factor. Genes Dev. 10 2265-2275.