메뉴 건너뛰기




Volumn 36, Issue 5, 2009, Pages 312-318

High resolution imaging of epithelial injury in the sheep cervicovaginal tract: A promising model for testing safety of candidate microbicides

Author keywords

[No Author keywords available]

Indexed keywords

BENZALKONIUM CHLORIDE; MICROBICIDE; BENZALKONIUM; TOPICAL ANTIINFECTIVE AGENT;

EID: 67649935663     PISSN: 01485717     EISSN: None     Source Type: Journal    
DOI: 10.1097/OLQ.0b013e31819496e4     Document Type: Article
Times cited : (51)

References (39)
  • 1
    • 84888540312 scopus 로고    scopus 로고
    • WHO/CONRAD. Technical Consultation on Nonoxynol-9. Conrad. Geneva, Switzerland: World Health Organization; 2001.
    • WHO/CONRAD. Technical Consultation on Nonoxynol-9. Conrad. Geneva, Switzerland: World Health Organization; 2001.
  • 2
    • 0037190597 scopus 로고    scopus 로고
    • Effectiveness of COL-1492, a nonoxynol-9 vaginal gel, on HIV-1 transmission in female sex workers: A randomised controlled trial
    • Van Damme L, Ramjee G, Alary M, et al. Effectiveness of COL-1492, a nonoxynol-9 vaginal gel, on HIV-1 transmission in female sex workers: a randomised controlled trial. Lancet 2002; 360:971-977.
    • (2002) Lancet , vol.360 , pp. 971-977
    • Van Damme, L.1    Ramjee, G.2    Alary, M.3
  • 3
    • 0026684234 scopus 로고
    • Efficacy of nonoxynol-9 contraceptive sponge use in preventing heterosexual acquisition of HIV in Nairobi prostitutes
    • Kreiss J, Ngugi E, Holmes K, et al. Efficacy of nonoxynol-9 contraceptive sponge use in preventing heterosexual acquisition of HIV in Nairobi prostitutes. JAMA 1992; 268:477-482.
    • (1992) JAMA , vol.268 , pp. 477-482
    • Kreiss, J.1    Ngugi, E.2    Holmes, K.3
  • 4
    • 34547571735 scopus 로고    scopus 로고
    • South Africa's experience of the closure of the cellulose sulphate microbicide trial
    • Ramjee G, Govinden R, Morar NS, et al. South Africa's experience of the closure of the cellulose sulphate microbicide trial. PLoS Med 2007; 4:1167.
    • (2007) PLoS Med , vol.4 , pp. 1167
    • Ramjee, G.1    Govinden, R.2    Morar, N.S.3
  • 5
    • 0027312868 scopus 로고
    • Barrier contraceptive use and HIV infection among high-risk women in Cameroon
    • Zekeng L, Feldblum PJ, Oliver RM, et al. Barrier contraceptive use and HIV infection among high-risk women in Cameroon. AIDS 1993; 7:725-731.
    • (1993) AIDS , vol.7 , pp. 725-731
    • Zekeng, L.1    Feldblum, P.J.2    Oliver, R.M.3
  • 6
    • 0033965025 scopus 로고    scopus 로고
    • Safety of multiple daily applications of COL-1492, a nonoxynol-9 vaginal gel, among female sex workers
    • Van Damme L, Chandeying V, Ramjee G, et al. Safety of multiple daily applications of COL-1492, a nonoxynol-9 vaginal gel, among female sex workers. AIDS 2000; 14:85-88.
    • (2000) AIDS , vol.14 , pp. 85-88
    • Van Damme, L.1    Chandeying, V.2    Ramjee, G.3
  • 7
    • 0036217080 scopus 로고    scopus 로고
    • Preclinical evaluation of sodium cellulose sulfate (Ushercell) as a contraceptive antimicrobial agent
    • Anderson RA, Feathergill KA, Diao XH, et al. Preclinical evaluation of sodium cellulose sulfate (Ushercell) as a contraceptive antimicrobial agent. J Androl 2002; 23:426-438.
    • (2002) J Androl , vol.23 , pp. 426-438
    • Anderson, R.A.1    Feathergill, K.A.2    Diao, X.H.3
  • 8
    • 34547841571 scopus 로고    scopus 로고
    • Safety and acceptability of 6% cellulose sulfate vaginal gel applied four times per day for 14 days
    • Doh AS, Ngoh N, Roddy R, et al. Safety and acceptability of 6% cellulose sulfate vaginal gel applied four times per day for 14 days. Contraception 2007; 76:245-249.
    • (2007) Contraception , vol.76 , pp. 245-249
    • Doh, A.S.1    Ngoh, N.2    Roddy, R.3
  • 9
    • 0036790651 scopus 로고    scopus 로고
    • Entry of inflammatory cells into the mouse vagina following application of candidate microbicides
    • Milligan GN, Dudley KL, Bourne N, et al. Entry of inflammatory cells into the mouse vagina following application of candidate microbicides. Sex Transm Dis 2002; 29:597-605.
    • (2002) Sex Transm Dis , vol.29 , pp. 597-605
    • Milligan, G.N.1    Dudley, K.L.2    Bourne, N.3
  • 10
    • 33746646763 scopus 로고    scopus 로고
    • Vaginal microbicides: Detecting toxicities in vivo that paradoxically increase pathogen transmission
    • Cone RA, Hoen T, Wong X, et al. Vaginal microbicides: detecting toxicities in vivo that paradoxically increase pathogen transmission. BMC Infect Dis 2006; 6:90.
    • (2006) BMC Infect Dis , vol.6 , pp. 90
    • Cone, R.A.1    Hoen, T.2    Wong, X.3
  • 11
    • 34247534517 scopus 로고    scopus 로고
    • A comprehensive murine model to evaluate topical vaginal microbicides: Mucosal inflammation and susceptibility to genital herpes as surrogate markers of safety
    • Galen BT, Martin AP, Hazrati E, et al. A comprehensive murine model to evaluate topical vaginal microbicides: Mucosal inflammation and susceptibility to genital herpes as surrogate markers of safety. J Inf Dis 2007; 195:1332-1339.
    • (2007) J Inf Dis , vol.195 , pp. 1332-1339
    • Galen, B.T.1    Martin, A.P.2    Hazrati, E.3
  • 12
    • 11144357239 scopus 로고    scopus 로고
    • Mouse model of cervicovaginal toxicity and inflammation for preclinical evaluation of topical vaginal microbicides
    • Catalone BJ, Kish-Catalone TM, Budgeon LR, et al. Mouse model of cervicovaginal toxicity and inflammation for preclinical evaluation of topical vaginal microbicides. Antimicrob Agents Chemother 2004; 48: 1837-1847.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 1837-1847
    • Catalone, B.J.1    Kish-Catalone, T.M.2    Budgeon, L.R.3
  • 13
    • 0029822006 scopus 로고    scopus 로고
    • Effects of nonoxynol-9 on vaginal microflora and chlamydial infection in a monkey model
    • Patton DL, Kidder GG, Sweeney YC, et al. Effects of nonoxynol-9 on vaginal microflora and chlamydial infection in a monkey model. Sex Transm Dis 1996; 23:461-464.
    • (1996) Sex Transm Dis , vol.23 , pp. 461-464
    • Patton, D.L.1    Kidder, G.G.2    Sweeney, Y.C.3
  • 14
    • 0033026047 scopus 로고    scopus 로고
    • Effects of multiple applications of benzalkonium chloride and nonoxynol 9 on the vaginal epithelium in the pigtailed macaque (Macaca nemestrina)
    • Patton DL, Kidder GG, Cosgrove-Sweeney Y, et al. Effects of multiple applications of benzalkonium chloride and nonoxynol 9 on the vaginal epithelium in the pigtailed macaque (Macaca nemestrina). Am J Obstet Gynecol 1999; 180:1080-1087.
    • (1999) Am J Obstet Gynecol , vol.180 , pp. 1080-1087
    • Patton, D.L.1    Kidder, G.G.2    Cosgrove-Sweeney, Y.3
  • 16
    • 0345360806 scopus 로고    scopus 로고
    • Progesterone implants enhance SIV vaginal transmission and early virus load
    • Marx PA, Spira Al, Gettie A, et al. Progesterone implants enhance SIV vaginal transmission and early virus load. Nat Med 1996; 2:1084-1089.
    • (1996) Nat Med , vol.2 , pp. 1084-1089
    • Marx, P.A.1    Spira, A.2    Gettie, A.3
  • 17
    • 84888517071 scopus 로고    scopus 로고
    • Safety of tenofovir gel in a comprehensive murine model. Microbicides [Abstract AO9-389]
    • In press
    • Herold B. Safety of tenofovir gel in a comprehensive murine model. Microbicides [Abstract AO9-389]. In press.
    • Herold, B.1
  • 18
    • 42949135368 scopus 로고    scopus 로고
    • Application of optical coherence tomography for monitoring changes in cervicovaginal epithelial morphology in macaques: Potential for assessment of microbicide safety
    • Vincent KL, Bell BA, Rosenthal SL, et al. Application of optical coherence tomography for monitoring changes in cervicovaginal epithelial morphology in macaques: Potential for assessment of microbicide safety. Sex Transm Dis 2008; 35:269-275.
    • (2008) Sex Transm Dis , vol.35 , pp. 269-275
    • Vincent, K.L.1    Bell, B.A.2    Rosenthal, S.L.3
  • 19
    • 2942538290 scopus 로고    scopus 로고
    • Diagnostic efficacy of optical coherence tomography in the management of preinvasive and invasive cancer of uterine cervix and vulva
    • Escobar PF, Belinson JL, White A, et al. Diagnostic efficacy of optical coherence tomography in the management of preinvasive and invasive cancer of uterine cervix and vulva. Int J Gynecol Cancer 2004; 14:470-474.
    • (2004) Int J Gynecol Cancer , vol.14 , pp. 470-474
    • Escobar, P.F.1    Belinson, J.L.2    White, A.3
  • 20
    • 42249111699 scopus 로고    scopus 로고
    • In vivo optical coherence tomography imaging of preinvasive bronchial lesions
    • Lam S, Standish B, Baldwin C, et al. In vivo optical coherence tomography imaging of preinvasive bronchial lesions. Clin Cancer Res 2008; 14:2006-2011.
    • (2008) Clin Cancer Res , vol.14 , pp. 2006-2011
    • Lam, S.1    Standish, B.2    Baldwin, C.3
  • 21
    • 0029767463 scopus 로고    scopus 로고
    • Macular disease and optical coherence tomography
    • Coker JG, Duker JS. Macular disease and optical coherence tomography. Curr Opin Ophthalmol 1996; 7:33-38.
    • (1996) Curr Opin Ophthalmol , vol.7 , pp. 33-38
    • Coker, J.G.1    Duker, J.S.2
  • 22
    • 67651122232 scopus 로고    scopus 로고
    • Manual for the standardization of colposcopy for the evaluation of vaginal products
    • WHO/CONRAD
    • WHO/CONRAD. Manual for the standardization of colposcopy for the evaluation of vaginal products, Update 2004. Punta Cana, Dominican Republic: CONRAD/WHO, 2004.
    • (2004) Update 2004. Punta Cana, Dominican Republic: CONRAD/WHO
  • 23
    • 0032723177 scopus 로고    scopus 로고
    • The effect of one injection of Depo-Provera on the human vaginal epithelium and cervical ectopy
    • Mauck CK, Callahan MM, Baker J, et al. The effect of one injection of Depo-Provera on the human vaginal epithelium and cervical ectopy. Contraception 1999; 60:15-24.
    • (1999) Contraception , vol.60 , pp. 15-24
    • Mauck, C.K.1    Callahan, M.M.2    Baker, J.3
  • 24
    • 0037665061 scopus 로고    scopus 로고
    • Magnetic resonance imaging anatomy of the female genitalia in premenopausal and postmenopausal women
    • Suh DD, Yang CC, Cao Y, et al. Magnetic resonance imaging anatomy of the female genitalia in premenopausal and postmenopausal women. J Urol 2003; 170:138-144.
    • (2003) J Urol , vol.170 , pp. 138-144
    • Suh, D.D.1    Yang, C.C.2    Cao, Y.3
  • 26
    • 0033787718 scopus 로고    scopus 로고
    • Epithelial cell layer thickness and immune cell populations in the normal human vagina at different stages of the menstrual cycle
    • Patton DP, Thwin SS, Meier A, et al. Epithelial cell layer thickness and immune cell populations in the normal human vagina at different stages of the menstrual cycle. Am J Obstet Gynecol 2000; 183:967-973.
    • (2000) Am J Obstet Gynecol , vol.183 , pp. 967-973
    • Patton, D.P.1    Thwin, S.S.2    Meier, A.3
  • 29
    • 81855219579 scopus 로고    scopus 로고
    • Optical coherence tomography in the evaluation of cervical dysplasia
    • Paper presented at: February, New Orleans, LA. Abstract 40
    • Vincent KL, Levine L, Bell BA, et al. Optical coherence tomography in the evaluation of cervical dysplasia. Paper presented at: 34th Annual Meeting of the Society of Gynecologic Oncologists; February 2003; New Orleans, LA. Abstract 40.
    • (2003) 34th Annual Meeting of the Society of Gynecologic Oncologists
    • Vincent, K.L.1    Levine, L.2    Bell, B.A.3
  • 30
    • 33750337283 scopus 로고    scopus 로고
    • Vaginal and rectal topical microbicide development: Safety and efficacy of 1.0% Savvy (C31G) in the pigtailed macaque
    • Patton DL, Cosgrove-Sweeney YT, Balkus JE, et al. Vaginal and rectal topical microbicide development: Safety and efficacy of 1.0% Savvy (C31G) in the pigtailed macaque. Sex Transm Dis 2006; 33:691-695.
    • (2006) Sex Transm Dis , vol.33 , pp. 691-695
    • Patton, D.L.1    Cosgrove-Sweeney, Y.T.2    Balkus, J.E.3
  • 31
    • 36349021921 scopus 로고    scopus 로고
    • Phase I safety trial of two vaginal microbicide gels (Acidform or BufferGel) used with a diaphragm compared to KY Jelly used with a diaphragm
    • Williams DL, Newman DR, Ballagh SA, et al. Phase I safety trial of two vaginal microbicide gels (Acidform or BufferGel) used with a diaphragm compared to KY Jelly used with a diaphragm. Sex Transm Dis 2007; 34:977-984.
    • (2007) Sex Transm Dis , vol.34 , pp. 977-984
    • Williams, D.L.1    Newman, D.R.2    Ballagh, S.A.3
  • 32
    • 22244484135 scopus 로고    scopus 로고
    • A study of the potential of the pig as a model for the vaginal irritancy of benzalkonium chloride in comparison to the nonirritant microbicide PHI-443 and the spermi-cide vanadocene dithiocarbamate
    • D' Cruz OJ, Erbeck D, Uckun FM. A study of the potential of the pig as a model for the vaginal irritancy of benzalkonium chloride in comparison to the nonirritant microbicide PHI-443 and the spermi-cide vanadocene dithiocarbamate. Toxic Path 2005; 33:465-476.
    • (2005) Toxic Path , vol.33 , pp. 465-476
    • D' Cruz, O.J.1    Erbeck, D.2    Uckun, F.M.3
  • 33
    • 0030770786 scopus 로고    scopus 로고
    • A phase I comparative study of contraceptive vaginal films containing benzalkonium chloride and nonoxynol-9. Postcoital testing and colposcopy
    • Mauck CK, Baker JM, Barr SP, et al. A phase I comparative study of contraceptive vaginal films containing benzalkonium chloride and nonoxynol-9. Postcoital testing and colposcopy. Contraception 1997; 56:89-96.
    • (1997) Contraception , vol.56 , pp. 89-96
    • Mauck, C.K.1    Baker, J.M.2    Barr, S.P.3
  • 34
    • 0025948845 scopus 로고
    • Cardiopulmonary reference standards in the pregnant sheep (Ovis aries): A comparative study of ovine and human physiology in obstetrics
    • Cissik JH, Ehler WJ, Hankins GD, et al. Cardiopulmonary reference standards in the pregnant sheep (Ovis aries): A comparative study of ovine and human physiology in obstetrics. Comp Biochem Physiol A Comp Physiol 1991; 100:877-880.
    • (1991) Comp Biochem Physiol A Comp Physiol , vol.100 , pp. 877-880
    • Cissik, J.H.1    Ehler, W.J.2    Hankins, G.D.3
  • 35
    • 4344568724 scopus 로고    scopus 로고
    • A comparison of techniques to assess cervicovaginal irritation and evaluation of the variability between two observers
    • Ballagh SA, Mauck CK, Henry D, et al. A comparison of techniques to assess cervicovaginal irritation and evaluation of the variability between two observers. Contraception 2004; 70:241-249.
    • (2004) Contraception , vol.70 , pp. 241-249
    • Ballagh, S.A.1    Mauck, C.K.2    Henry, D.3
  • 36
    • 38549116136 scopus 로고    scopus 로고
    • Differentiating normal from abnormal rates of genital epithelial findings in vaginal microbicide trials
    • van de Wijgert JH, Kilmarx PH, Jones HE, et al. Differentiating normal from abnormal rates of genital epithelial findings in vaginal microbicide trials. Contraception 2008; 77:122-129.
    • (2008) Contraception , vol.77 , pp. 122-129
    • van de Wijgert, J.H.1    Kilmarx, P.H.2    Jones, H.E.3
  • 37
    • 33749864595 scopus 로고    scopus 로고
    • Cyclic changes in the vaginal epithelium of normal rhesus macaques
    • Poonia B, Walter L, Dufour J, et al. Cyclic changes in the vaginal epithelium of normal rhesus macaques. J Endocrinol 2006; 190:829-835.
    • (2006) J Endocrinol , vol.190 , pp. 829-835
    • Poonia, B.1    Walter, L.2    Dufour, J.3
  • 38
    • 4143134237 scopus 로고    scopus 로고
    • Topical estrogen protects against SIV vaginal transmission without evidence of systemic effect
    • Smith SM, Mefford M, Sodora D, et al. Topical estrogen protects against SIV vaginal transmission without evidence of systemic effect. AIDS 2004; 18:1637-1643.
    • (2004) AIDS , vol.18 , pp. 1637-1643
    • Smith, S.M.1    Mefford, M.2    Sodora, D.3
  • 39
    • 0027186275 scopus 로고
    • Nonoxynol-9 protects mice against vaginal transmission of genital herpes infections
    • Whaley KJ, Barratt RA, Zeitlin L, et al. Nonoxynol-9 protects mice against vaginal transmission of genital herpes infections. J Infect Dis 1993; 168:1009-1011.
    • (1993) J Infect Dis , vol.168 , pp. 1009-1011
    • Whaley, K.J.1    Barratt, R.A.2    Zeitlin, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.