A study of the potential of the pig as a model for the vaginal irritancy of benzalkonium chloride in comparison to the nonirritant microbicide PHI-443 and the spermicide vanadocene dithiocarbamate

Toxicologic Pathology

Volumn 33, Issue 4, 2005, Pages 465-476

  D'Cruz, Osmond J ^a,b   Erbeck, Douglas ^a   Uckun, Fatih M ^a  

^a PARKER HUGHES INSTITUTE   (United States)

^b Paradigm Pharmaceuticals   (United States)

Author keywords

Cytokines; HIV AIDS; Inflammation; Microbicide; Porcine; Spermicide; Vagina

Indexed keywords

BENZALKONIUM CHLORIDE; BIOLOGICAL MARKER; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MICROBICIDE; PHI 443; SPERMICIDAL AGENT; THIOPHENE THIOUREA; THIOUREA DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VANADOCENE DITHIOCARBAMATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HISTOLOGY; NONHUMAN; PRIORITY JOURNAL; SCORING SYSTEM; SWINE; UTERINE CERVIX CYTOLOGY; VAGINA DISEASE; VAGINA MUCOSA;

ANIMALS; ANTI-INFECTIVE AGENTS, LOCAL; BENZALKONIUM COMPOUNDS; CYTOKINES; FEMALE; FLOW CYTOMETRY; IRRIGATION; IRRITANTS; MODELS, ANIMAL; PYRIDINES; SKIN IRRITANCY TESTS; SPERMATOCIDAL AGENTS; SWINE; THIOUREA; VAGINA; VANADIUM COMPOUNDS;

SUIDAE; SUS SCROFA; SUS SCROFA DOMESTICA;

EID: 22244484135     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1080/01926230590959866     Document Type: Article

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