Real-time fluorescence monitoring of GSK3β-catalyzed phosphoryation by use of a BODIPY-based Zn(II)-Dpa chemosensor

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 15, 2009, Pages 4175-4177

  Sakamoto, Takashi ^a   Inoue, Masa aki ^a   Ojida, Akio ^a   Hamachi, Itaru ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Fluorescent chemosensor; GSK3 ; Inhibitor assay; Kinase; Protein phosphorylation; Real time monitoring

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA; ZINC;

ARTICLE; CATALYSIS; ENZYME BINDING; ENZYME STRUCTURE; FLUORESCENCE SPECTROSCOPY; GLYCOGEN METABOLISM; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION;

ANIMALS; BORON COMPOUNDS; CATALYSIS; CHEMISTRY, PHARMACEUTICAL; DRUG DESIGN; FLUORESCENT DYES; GLYCOGEN SYNTHASE KINASE 3; HUMANS; KINETICS; MODELS, CHEMICAL; PEPTIDES; PHOSPHORYLATION; RABBITS; TIME FACTORS; ZINC;

EID: 67649909791     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.05.121     Document Type: Article

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