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Metal-ion-induced conformational stabilization of α-helix peptide or protein: (a) Cline, D. J.; Thorpe, C.; Schneider, J. P. J. Am. Chem. Soc. 2003, 125, 2923. (b) Mito-oka, Y.; Tsukiji, S.; Hiraoka, T.; Kasagi, N.; Shinkai, S.; Hamachi, I. Tetrahedon Lett. 2001, 42, 7059. (c) Hamachi, I.; Kasagi, N.; Nagase, T.; Kiyonaka, S.; Mito-oka, Y.; Shinkai, S. Chem. Lett. 2001, 16. (d) Hamachi, I.; Eboshi, R.; Watanabe, J.; Shinkai, S. J. Am. Chem. Soc. 2000, 122, 4529, (e) Hamachi, I.; Yamada, Y.; Matsugi, T.; Shinkai, S. Chem. Eur. J. 1999, 5, 1503. (f) Ghadiri, M. R.; Fernholz, A. K. J. Am. Chem. Soc. 1990, 112, 9633. (g) Ghadiri, M. R.; Choi, C. J. Am. Chem. Soc. 1990, 112, 1630. (h) Ruan, F.; Chen, Y.; Hopkins, P. B. J. Am. Chem. Soc. 1990, 112, 9403.
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Metal-ion-induced conformational stabilization of α-helix peptide or protein: (a) Cline, D. J.; Thorpe, C.; Schneider, J. P. J. Am. Chem. Soc. 2003, 125, 2923. (b) Mito-oka, Y.; Tsukiji, S.; Hiraoka, T.; Kasagi, N.; Shinkai, S.; Hamachi, I. Tetrahedon Lett. 2001, 42, 7059. (c) Hamachi, I.; Kasagi, N.; Nagase, T.; Kiyonaka, S.; Mito-oka, Y.; Shinkai, S. Chem. Lett. 2001, 16. (d) Hamachi, I.; Eboshi, R.; Watanabe, J.; Shinkai, S. J. Am. Chem. Soc. 2000, 122, 4529, (e) Hamachi, I.; Yamada, Y.; Matsugi, T.; Shinkai, S. Chem. Eur. J. 1999, 5, 1503. (f) Ghadiri, M. R.; Fernholz, A. K. J. Am. Chem. Soc. 1990, 112, 9633. (g) Ghadiri, M. R.; Choi, C. J. Am. Chem. Soc. 1990, 112, 1630. (h) Ruan, F.; Chen, Y.; Hopkins, P. B. J. Am. Chem. Soc. 1990, 112, 9403.
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11944257538
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Metal-ion-induced conformational stabilization of α-helix peptide or protein: (a) Cline, D. J.; Thorpe, C.; Schneider, J. P. J. Am. Chem. Soc. 2003, 125, 2923. (b) Mito-oka, Y.; Tsukiji, S.; Hiraoka, T.; Kasagi, N.; Shinkai, S.; Hamachi, I. Tetrahedon Lett. 2001, 42, 7059. (c) Hamachi, I.; Kasagi, N.; Nagase, T.; Kiyonaka, S.; Mito-oka, Y.; Shinkai, S. Chem. Lett. 2001, 16. (d) Hamachi, I.; Eboshi, R.; Watanabe, J.; Shinkai, S. J. Am. Chem. Soc. 2000, 122, 4529, (e) Hamachi, I.; Yamada, Y.; Matsugi, T.; Shinkai, S. Chem. Eur. J. 1999, 5, 1503. (f) Ghadiri, M. R.; Fernholz, A. K. J. Am. Chem. Soc. 1990, 112, 9633. (g) Ghadiri, M. R.; Choi, C. J. Am. Chem. Soc. 1990, 112, 1630. (h) Ruan, F.; Chen, Y.; Hopkins, P. B. J. Am. Chem. Soc. 1990, 112, 9403.
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0025675385
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Metal-ion-induced conformational stabilization of α-helix peptide or protein: (a) Cline, D. J.; Thorpe, C.; Schneider, J. P. J. Am. Chem. Soc. 2003, 125, 2923. (b) Mito-oka, Y.; Tsukiji, S.; Hiraoka, T.; Kasagi, N.; Shinkai, S.; Hamachi, I. Tetrahedon Lett. 2001, 42, 7059. (c) Hamachi, I.; Kasagi, N.; Nagase, T.; Kiyonaka, S.; Mito-oka, Y.; Shinkai, S. Chem. Lett. 2001, 16. (d) Hamachi, I.; Eboshi, R.; Watanabe, J.; Shinkai, S. J. Am. Chem. Soc. 2000, 122, 4529, (e) Hamachi, I.; Yamada, Y.; Matsugi, T.; Shinkai, S. Chem. Eur. J. 1999, 5, 1503. (f) Ghadiri, M. R.; Fernholz, A. K. J. Am. Chem. Soc. 1990, 112, 9633. (g) Ghadiri, M. R.; Choi, C. J. Am. Chem. Soc. 1990, 112, 1630. (h) Ruan, F.; Chen, Y.; Hopkins, P. B. J. Am. Chem. Soc. 1990, 112, 9403.
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Chen, Y.2
Hopkins, P.B.3
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19
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0041404127
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note
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Synthesis and characterization of these receptors were conducted according to the method described in the Supporting Information.
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21
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0041905234
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note
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In 6,6′-Zn(Dpa)-Bpy, the nitrogens of the bipyridyl ring are involved in the chelation to zinc(II), and as a result, there is not any labile site for peptide binding in the zinc complex.
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23
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0022494971
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Ellis, L.; Clauser, E.; Morgan, D. O.; Edery, M.; Roth, R. A.; Rutter, W. J. Cell 1986, 45, 721.
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Ellis, L.1
Clauser, E.2
Morgan, D.O.3
Edery, M.4
Roth, R.A.5
Rutter, W.J.6
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24
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0345476725
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(b) Rosen, O. M.; Herrera, R.; Olowe, Y.; Petruzzelli, L. M.; Cobb, M. H. Proc. Natl. Acad. Sci. U.S.A. 1983, 80, 3237.
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Rosen, O.M.1
Herrera, R.2
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Petruzzelli, L.M.4
Cobb, M.H.5
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25
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0000287898
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Hubbard, S. R. EMBO J. 1997, 16, 5573. X-ray crystallographic structural analysis of IRK indicated that the distance between pY1158 and pY1162 is approximately 18 Å.
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EMBO J.
, vol.16
, pp. 5573
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Hubbard, S.R.1
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26
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0041404140
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note
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The tilted conformational change induced by peptide binding may be coincident with the decrease of the fluorescence intensity of 5,5′-Zn(Dpa)-Bpy.
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