Multimodal Analgesia for Hip Arthroplasty

Orthopedic Clinics of North America

Volumn 40, Issue 3, 2009, Pages 377-387

  Tang, Raymond ^a   Evans, Holly ^b   Chaput, Alan ^a   Kim, Christopher ^b  

^a UNIVERSITY OF OTTAWA   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Cyclo oxygenase II inhibitors; Gabapentinoids; Hip arthroplasty; Nonsteroidal anti inflammatory drugs; Postoperative analgesia

Indexed keywords

ADRENALIN; ANALGESIC AGENT; ANTACID AGENT; BUPIVACAINE; CEFUROXIME; CELECOXIB; CLONIDINE; CYCLOOXYGENASE 2 INHIBITOR; DEXAMETHASONE; GABAPENTIN; IBUPROFEN; KETAMINE; KETOROLAC; LOCAL ANESTHETIC AGENT; METHYLPREDNISOLONE; MORPHINE; NARCOTIC ANALGESIC AGENT; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE; PARACETAMOL; PARECOXIB; PLACEBO; PREGABALIN; ROFECOXIB; ROPIVACAINE; SEDATIVE AGENT; TRAMADOL;

ADJUVANT THERAPY; BALANCE DISORDER; BLEEDING; BRADYCARDIA; BRONCHOSPASM; CARDIOVASCULAR EFFECT; CLINICAL TRIAL; COMBINATION CHEMOTHERAPY; DIZZINESS; DROWSINESS; DRUG BIOAVAILABILITY; DRUG DOSE REDUCTION; DRUG DOSE REGIMEN; DRUG DOSE TITRATION; DRUG EFFICACY; DRUG INDUCED HEADACHE; DRUG POTENTIATION; DRUG SAFETY; DRUG WITHDRAWAL; DYSPHORIA; EPIDURAL ANESTHESIA; EPIDURAL HEMATOMA; GASTRITIS; GASTROINTESTINAL DISEASE; GASTROINTESTINAL SYMPTOM; HALLUCINATION; HEART INFARCTION; HIP ARTHROPLASTY; HUMAN; HYPOTENSION; KIDNEY DYSFUNCTION; LIVER TOXICITY; LOCAL ANESTHESIA; MONOTHERAPY; NAUSEA; NAUSEA AND VOMITING; NERVE BLOCK; NONHUMAN; PERIOPERATIVE PERIOD; PERIPHERAL EDEMA; POSTOPERATIVE ANALGESIA; POSTOPERATIVE PAIN; PRIORITY JOURNAL; REVIEW; SEDATION; SIDE EFFECT; SINGLE DRUG DOSE; SOMNOLENCE; SPINAL ANESTHESIA; STOMACH ULCER; SWEATING; SYSTEMIC DISEASE; THROMBOCYTE DYSFUNCTION; URINE RETENTION; VOMITING; XEROSTOMIA;

AMINES; ANALGESIA; ANALGESICS; ANESTHETICS, LOCAL; ARTHROPLASTY, REPLACEMENT, HIP; COMBINED MODALITY THERAPY; CYCLOHEXANECARBOXYLIC ACIDS; CYCLOOXYGENASE 2 INHIBITORS; GAMMA-AMINOBUTYRIC ACID; HUMANS; PAIN, POSTOPERATIVE;

EID: 67649819463     PISSN: 00305898     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ocl.2009.04.001     Document Type: Review

References (92)

1. Williams O., Fitzpatrick R., Hajat S., et al. Mortality, morbidity, and 1-year outcomes of primary elective total hip arthroplasty. J Arthroplasty 17 2 (2002) 165-171
2. Nikolajsen L., Brandsborg B., Lucht U., et al. Chronic pain following total hip arthroplasty: a nationwide questionnaire study. Acta Anaesthesiol Scand 50 4 (2006) 495-500
3. Fischer H.B., and Simanski C.J. A procedure-specific systematic review and consensus recommendations for analgesia after total hip replacement. Anaesthesia 60 12 (2005) 1189-1202
4. Buvanendran A., Kroin J.S., Tuman K.J., et al. Effects of perioperative administration of a selective cyclooxygenase 2 inhibitor on pain management and recovery of function after knee replacement: a randomized controlled trial. JAMA 290 18 (2003) 2411-2418
5. Kehlet H., and Dahl J.B. The value of "multimodal" or "balanced analgesia" in postoperative pain treatment. Anesth Analg 77 5 (1993) 1048-1056
6. Guignard B., Bossard A.E., Coste C., et al. Acute opioid tolerance: intraoperative remifentanil increases postoperative pain and morphine requirement. Anesthesiology 93 2 (2000) 409-417
7. Mao J. Opioid-induced abnormal pain sensitivity: implications in clinical opioid therapy. Pain 100 3 (2002) 213-217
8. Chia Y.Y., Liu K., Wang J.J., et al. Intraoperative high dose fentanyl induces postoperative fentanyl tolerance. Can J Anaesth 46 9 (1999) 872-877
9. Ameer B., Divoll M., Abernethy D.R., et al. Absolute and relative bioavailability of oral acetaminophen preparations. J Pharm Sci 72 8 (1983) 955-958
10. Remy C., Marret E., and Bonnet F. Effects of acetaminophen on morphine side-effects and consumption after major surgery: meta-analysis of randomized controlled trials. Br J Anaesth 94 4 (2005) 505-513
11. Elia N., Lysakowski C., and Tramer M.R. Does multimodal analgesia with acetaminophen, nonsteroidal antiinflammatory drugs, or selective cyclooxygenase-2 inhibitors and patient-controlled analgesia morphine offer advantages over morphine alone? Meta-analyses of randomized trials. Anesthesiology 103 6 (2005) 1296-1304
12. Toms L., McQuay H.J., Derry S., et al. Single dose oral paracetamol (acetaminophen) for postoperative pain in adults. Cochrane Database Syst Rev 4 (2008) CD004602
13. Romsing J., and Moiniche S. A systematic review of COX-2 inhibitors compared with traditional NSAIDs, or different COX-2 inhibitors for post-operative pain. Acta Anaesthesiol Scand 48 5 (2004) 525-546
14. Romsing J., Moiniche S., Mathiesen O., et al. Reduction of opioid-related adverse events using opioid-sparing analgesia with COX-2 inhibitors lacks documentation: a systematic review. Acta Anaesthesiol Scand 49 2 (2005) 133-142
15. Straube S., Derry S., McQuay H.J., et al. Effect of preoperative Cox-II-selective NSAIDs (coxibs) on postoperative outcomes: a systematic review of randomized studies. Acta Anaesthesiol Scand 49 5 (2005) 601-613
16. Malan Jr. T.P., Marsh G., Hakki S.I., et al. Parecoxib sodium, a parenteral cyclooxygenase 2 selective inhibitor, improves morphine analgesia and is opioid-sparing following total hip arthroplasty. Anesthesiology 98 4 (2003) 950-956
17. Camu F., Beecher T., Recker D.P., et al. Valdecoxib, a COX-2-specific inhibitor, is an efficacious, opioid-sparing analgesic in patients undergoing hip arthroplasty. Am J Ther 9 1 (2002) 43-51
18. Reicin A., Brown J., Jove M., et al. Efficacy of single-dose and multidose rofecoxib in the treatment of post-orthopedic surgery pain. Am J Orthop 30 1 (2001) 40-48
19. Chan V.W., Clark A.J., Davis J.C., et al. The post-operative analgesic efficacy and tolerability of lumiracoxib compared with placebo and naproxen after total knee or hip arthroplasty. Acta Anaesthesiol Scand 49 10 (2005) 1491-1500
20. Rasmussen G.L., Malmstrom K., Bourne M.H., et al. Etoricoxib provides analgesic efficacy to patients after knee or hip replacement surgery: a randomized, double-blind, placebo-controlled study. Anesth Analg 101 4 (2005) 1104-1111
21. Bombardier C., Laine L., Reicin A., et al. Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group. N Engl J Med 343 21 (2000) 1520-1528
22. Harder A.T., and An Y.H. The mechanisms of the inhibitory effects of nonsteroidal anti-inflammatory drugs on bone healing: a concise review. J Clin Pharmacol 43 8 (2003) 807-815
23. Gilron I. Gabapentin and pregabalin for chronic neuropathic and early postsurgical pain: current evidence and future directions. Curr Opin Anaesthesiol 20 5 (2007) 456-472
24. Fink K., Dooley D.J., Meder W.P., et al. Inhibition of neuronal Ca(2+) influx by gabapentin and pregabalin in the human neocortex. Neuropharmacology 42 2 (2002) 229-236
25. Fehrenbacher J.C., Taylor C.P., and Vasko M.R. Pregabalin and gabapentin reduce release of substance P and CGRP from rat spinal tissues only after inflammation or activation of protein kinase C. Pain 105 1-2 (2003) 133-141
26. Li C.Y., Zhang X.L., Matthews E.A., et al. Calcium channel alpha2delta1 subunit mediates spinal hyperexcitability in pain modulation. Pain 125 1-2 (2006) 20-34
27. Luo Z.D., Chaplan S.R., Higuera E.S., et al. Upregulation of dorsal root ganglion (alpha)2(delta) calcium channel subunit and its correlation with allodynia in spinal nerve-injured rats. J Neurosci 21 6 (2001) 1868-1875
28. Newton R.A., Bingham S., Case P.C., et al. Dorsal root ganglion neurons show increased expression of the calcium channel alpha2delta-1 subunit following partial sciatic nerve injury. Brain Res Mol Brain Res 95 1-2 (2001) 1-8
29. Hill C.M., Balkenohl M., Thomas D.W., et al. Pregabalin in patients with postoperative dental pain. Eur J Pain 5 2 (2001) 119-124
30. Dahl J.B., Mathiesen O., and Moiniche S. 'Protective premedication': an option with gabapentin and related drugs? A review of gabapentin and pregabalin in in the treatment of post-operative pain. Acta Anaesthesiol Scand 48 9 (2004) 1130-1136
31. Ho K.Y., Gan T.J., and Habib A.S. Gabapentin and postoperative pain-a systematic review of randomized controlled trials. Pain 126 1-3 (2006) 91-101
32. Hurley R.W., Cohen S.P., Williams K.A., et al. The analgesic effects of perioperative gabapentin on postoperative pain: a meta-analysis. Reg Anesth Pain Med 31 3 (2006) 237-247
33. Mathiesen O., Moiniche S., and Dahl J.B. Gabapentin and postoperative pain: a qualitative and quantitative systematic review, with focus on procedure. BMC Anesthesiol 7 (2007) 6
34. Seib R.K., and Paul J.E. Preoperative gabapentin for postoperative analgesia: a meta-analysis. Can J Anaesth 53 5 (2006) 461-469
35. Tiippana E.M., Hamunen K., Kontinen V.K., et al. Do surgical patients benefit from perioperative gabapentin/pregabalin? A systematic review of efficacy and safety. Anesth Analg 104 6 (2007) 1545-1556
36. Peng P.W.H., Wijeysundera D.N., and Li C.C.F. Use of gabapentin for perioperative pain control-a meta-analysis. Pain Res Manag 12 2 (2007) 85-92
37. Al-Mujadi H., A-Refai A.R., Katzarov M.G., et al. Preemptive gabapentin reduces postoperative pain and opioid demand following thyroid surgery. Can J Anaesth 53 5 (2006) 268-273
38. Dirks J., Fredensborg B.B., Christensen D., et al. A randomized study of the effects of single-dose gabapentin versus placebo on postoperative pain and morphine consumption after mastectomy. Anesthesiology 97 3 (2002) 560-564
39. Rorarius M.G., Mennander S., Suominen P., et al. Gabapentin for the prevention of postoperative pain after vaginal hysterectomy. Pain 110 1-2 (2004) 175-181
40. Menigaux C., Adam F., Guignard B., et al. Preoperative gabapentin decreases anxiety and improves early functional recovery from knee surgery. Anesth Analg 100 5 (2005) 1394-1399
41. Pandey C.K., Navkar D.V., Giri P.J., et al. Evaluation of the optimal preemptive dose of gabapentin for postoperative pain relief after lumbar diskectomy: a randomized, double-blind, placebo-controlled study. J Neurosurg Anesthesiol 17 2 (2005) 65-68
42. Pandey C.K., Priye S., Singh S., et al. Preemptive use of gabapentin significantly decreases postoperative pain and rescue analgesic requirements in laparoscopic cholecystectomy. Can J Anaesth 51 4 (2004) 358-363
43. Pandey C.K., Sahay S., Gupta D., et al. Preemptive gabapentin decreases postoperative pain after lumbar discoidectomy. Can J Anaesth 51 10 (2004) 986-989
44. Pandey C.K., Singhal V., Kumar M., et al. Gabapentin provides effective postoperative analgesia whether administered pre-emptively or post-incision. Can J Anaesth 52 8 (2005) 827-831
45. Radhakrishnan M., Bithal P.K., and Chaturvedi A. Effect of preemptive gabapentin on postoperative pain relief and morphine consumption following lumbar laminectomy and discectomy: a randomized, double-blinded, placebo-controlled study. J Neurosurg Anesthesiol 17 3 (2005) 125-128
46. Tuncer S., Bariskaner H., Reisli R., et al. Effect of gabapentin on postoperative pain: a randomized, placebo-controlled clinical study. Pain Clin 17 1 (2005) 95-99
47. Turan A., Karamanlioglu B., Memis D., et al. The analgesic effects of gabapentin after total abdominal hysterectomy. Anesth Analg 98 5 (2004) 1370-1373
48. Turan A., Karamanlioglu B., Memis D., et al. Analgesic effects of gabapentin after spinal surgery. Anesthesiology 100 4 (2004) 935-938
49. Turan A., Memis D., Karamanlioglu B., et al. The analgesic effects of gabapentin in monitored anesthesia care for ear-nose-throat surgery. Anesth Analg 99 2 (2004) 375-378
50. Dierking G., Duedahl T.H., Rasmussen M.L., et al. Effects of gabapentin on postoperative morphine consumption and pain after abdominal hysterectomy: a randomized, double-blind trial. Acta Anaesthesiol Scand 48 3 (2004) 322-327
51. Fassoulaki A., Stamatakis E., Petropoulos G., et al. Gabapentin attenuates late but not acute pain after abdominal hysterectomy. Eur J Anaesthesiol 23 2 (2006) 136-141
52. Fassoulaki A., Triga A., Melemeni A., et al. Multimodal analgesia with gabapentin and local anesthetics prevents acute and chronic pain after breast surgery for cancer. [see comment]. Anesth Analg 101 5 (2005) 1427-1432
53. Fassoulaki A., Patris K., Sarantopoulos C., et al. The analgesic effect of gabapentin and mexiletine after breast surgery for cancer. Anesth Analg 95 4 (2002) 985-991
54. Gilron I., Orr E., Tu D., et al. A placebo-controlled randomized clinical trial of perioperative administration of gabapentin, rofecoxib and their combination for spontaneous and movement-evoked pain after abdominal hysterectomy. Pain 113 1-2 (2005) 191-200
55. Mikkelsen S., Hilsted K.L., Andersen P.J., et al. The effect of gabapentin on post-operative pain following tonsillectomy in adults. Acta Anaesthesiol Scand 50 7 (2006) 809-815
56. Turan A., Kaya G., Karamanlioglu B., et al. Effect of oral gabapentin on postoperative epidural analgesia. Br J Anaesth 96 2 (2006) 242-246
57. Turan A., White P.F., Karamanlioglu B., et al. Gabapentin: an alternative to the cyclooxygenase-2 inhibitors for perioperative pain management. Anesth Analg 102 1 (2006) 175-181
58. Agarwal A., Gautam S., Gupta D., et al. Evaluation of a single preoperative dose of pregabalin for attenuation of postoperative pain after laparoscopic cholecystectomy. Br J Anaesth 101 5 (2008) 700-704
59. Jokela R., Ahonen J., Tallgren M., et al. Premedication with pregabalin 75 or 150 mg with ibuprofen to control pain after day-case gynaecological laparoscopic surgery. Br J Anaesth 100 6 (2008) 834-840
60. Jokela R., Ahonen J., Tallgren M., et al. A randomized controlled trial of perioperative administration of pregabalin for pain after laparoscopic hysterectomy. Pain 134 1-2 (2008) 106-112
61. Mathiesen O., Jacobsen L.S., Holm H.E., et al. Pregabalin and dexamethasone for postoperative pain control: a randomized controlled study in hip arthroplasty. Br J Anaesth 101 4 (2008) 535-541
62. Paech M.J., Goy R., Chua S., et al. A randomized, placebo-controlled trial of preoperative oral pregabalin for postoperative pain relief after minor gynecological surgery. Anesth Analg 105 5 (2007) 1449-1453
63. Mathiesen O., Rasmussen M.L., Dierking G., et al. Pregabalin and dexamethasone in combination with paracetamol for postoperative pain control after abdominal hysterectomy. a randomized clinical trial. Acta Anaesthesiol Scand 53 (2009) 227-235
64. Sabatowski R., Galvez R., Cherry D.A., et al. Pregabalin reduces pain and improves sleep and mood disturbances in patients with post-herpetic neuralgia: results of a randomised, placebo-controlled clinical trial. Pain 109 1-2 (2004) 26-35
65. Leung J.M., Sands L.P., Rico M., et al. Pilot clinical trial of gabapentin to decrease postoperative delirium in older patients. Neurology 67 7 (2006) 1251-1253
66. Scott L.J., and Perry C.M. Tramadol: a review of its use in perioperative pain. Drugs 60 1 (2000) 139-176
67. Stubhaug A., Grimstad J., and Breivik H. Lack of analgesic effect of 50 and 100 mg oral tramadol after orthopaedic surgery: a randomized, double-blind, placebo and standard active drug comparison. Pain 62 1 (1995) 111-118
68. Bell R.F., Dahl J.B., Moore R.A., et al. Perioperative ketamine for acute postoperative pain. Cochrane Database Syst Rev 1 (2006) CD004603
69. Elia N., and Tramer M.R. Ketamine and postoperative pain-a quantitative systematic review of randomised trials. Pain 113 1-2 (2005) 61-70
70. Kohrs R., and Durieux M.E. Ketamine: teaching an old drug new tricks. Anesth Analg 87 5 (1998) 1186-1193
71. Menigaux C., Fletcher D., Dupont X., et al. The benefits of intraoperative small-dose ketamine on postoperative pain after anterior cruciate ligament repair. Anesth Analg 90 1 (2000) 129-135
72. Menigaux C., Guignard B., Fletcher D., et al. Intraoperative small-dose ketamine enhances analgesia after outpatient knee arthroscopy. Anesth Analg 93 3 (2001) 606-612
73. Dobrydnjov I., Axelsson K., Gupta A., et al. Improved analgesia with clonidine when added to local anesthetic during combined spinal-epidural anesthesia for hip arthroplasty: a double-blind, randomized and placebo-controlled study. Acta Anaesthesiol Scand 49 4 (2005) 538-545
74. Milligan K.R., Convery P.N., Weir P., et al. The efficacy and safety of epidural infusions of levobupivacaine with and without clonidine for postoperative pain relief in patients undergoing total hip replacement. Anesth Analg 91 2 (2000) 393-397
75. Fogarty D.J., Carabine U.A., and Milligan K.R. Comparison of the analgesic effects of intrathecal clonidine and intrathecal morphine after spinal anaesthesia in patients undergoing total hip replacement. Br J Anaesth 71 5 (1993) 661-664
76. Grace D., Bunting H., Milligan K.R., et al. Postoperative analgesia after co-administration of clonidine and morphine by the intrathecal route in patients undergoing hip replacement. Anesth Analg 80 1 (1995) 86-91
77. Liu S.S., Richman J.M., Thirlby R.C., et al. Efficacy of continuous wound catheters delivering local anesthetic for postoperative analgesia: a quantitative and qualitative systematic review of randomized controlled trials. J Am Coll Surg 203 6 (2006) 914-932
78. Bianconi M., Ferraro L., Traina G.C., et al. Pharmacokinetics and efficacy of ropivacaine continuous wound instillation after joint replacement surgery. Br J Anaesth 91 6 (2003) 830-835
79. Parvataneni H.K., Shah V.P., Howard H., et al. Controlling pain after total hip and knee arthroplasty using a multimodal protocol with local periarticular injections: a prospective randomized study. J Arthroplasty 22 6 Suppl 2 (2007) 33-38
80. Toftdahl K., Nikolajsen L., Haraldsted V., et al. Comparison of peri- and intraarticular analgesia with femoral nerve block after total knee arthroplasty: a randomized clinical trial. Acta Orthop 78 2 (2007) 172-179
81. Andersen K.V., Pfeiffer-Jensen M., Haraldsted V., et al. Reduced hospital stay and narcotic consumption, and improved mobilization with local and intraarticular infiltration after hip arthroplasty: a randomized clinical trial of an intraarticular technique versus epidural infusion in 80 patients. Acta Orthop 78 2 (2007) 180-186
82. Brown S.L., and Morrison A.E. Local anesthetic infusion pump systems adverse events reported to the food and drug administration. Anesthesiology 100 (2004) 1305-1306
83. Gomoll A.H., Kang R.W., Williams J.M., et al. Chondrolysis after continuous intra-articular bupivacaine infusion: an experimental model investigating chondrotoxicity in the rabbit shoulder. Arthroscopy 22 8 (2006) 813-819
84. Horlocker T.T., Kopp S.L., Pagnano M.W., et al. Analgesia for total hip and knee arthroplasty: a multimodal pathway featuring peripheral nerve block. J Am Acad Orthop Surg 14 3 (2006) 126-135
85. Buckenmaier III C.C., Xenos J.S., and Nilsen S.M. Lumbar plexus block with perineural catheter and sciatic nerve block for total hip arthroplasty. J Arthroplasty 17 4 (2002) 499-502
86. Hebl J.R., Kopp S.L., Ali M.H., et al. A comprehensive anesthesia protocol that emphasizes peripheral nerve blockade for total knee and total hip arthroplasty. J Bone Joint Surg Am 87 Suppl 2 (2005) 63-70
87. Ilfeld B.M., Gearen P.F., Enneking F.K., et al. Total hip arthroplasty as an overnight-stay procedure using an ambulatory continuous psoas compartment nerve block: a prospective feasibility study. Reg Anesth Pain Med 31 2 (2006) 113-118
88. Ilfeld B.M., Ball S.T., Gearen P.F., et al. Ambulatory continuous posterior lumbar plexus nerve blocks after hip arthroplasty: a dual-center, randomized, triple-masked, placebo-controlled trial. Anesthesiology 109 3 (2008) 491-501
89. Siddiqui Z.I., Cepeda M.S., Denman W., et al. Continuous lumbar plexus block provides improved analgesia with fewer side effects compared with systemic opioids after hip arthroplasty: a randomized controlled trial. Reg Anesth Pain Med 32 5 (2007) 393-398
90. Mauermann W.J., Shilling A.M., and Zuo Z. A comparison of neuraxial block versus general anesthesia for elective total hip replacement: a meta-analysis. Anesth Analg 103 4 (2006) 1018-1025
91. Choi P.T., Bhandari M., Scott J., et al. Epidural analgesia for pain relief following hip or knee replacement. Cochrane Database Syst Rev 3 (2003) CD003071
92. Andersen L.J., Poulsen T., Krogh B., et al. Postoperative analgesia in total hip arthroplasty: a randomized double-blinded, placebo-controlled study on peroperative and postoperative ropivacaine, ketorolac, and adrenaline wound infiltration. Acta Orthop 78 2 (2007) 187-192