Chemopreventive effect of farnesol on DMBA/TPA-induced skin tumorigenesis: Involvement of inflammation, Ras-ERK pathway and apoptosis

Life Sciences

Volumn 85, Issue 5-6, 2009, Pages 196-205

  Chaudhary, Sandeep Chand ^a   Alam, Mohammad Sarwar ^a   Siddiqui, Mohammad Saeed ^a   Athar, Mohammad ^a,b  

^a HAMDARD UNIVERSITY   (India)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Apoptosis; Farnesol; Inflammation; Oxidative stress; Ras pathway; Skin tumorigenesis

Indexed keywords

7,12 DIMETHYLBENZ[A]ANTHRACENE; CYCLOOXYGENASE 2; FARNESOL; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; ORNITHINE DECARBOXYLASE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN BAX; PROTEIN BCL 2; RAF PROTEIN; RAS PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CHEMOPROPHYLAXIS; CONTROLLED STUDY; DNA FRAGMENTATION; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG MECHANISM; HYPERPLASIA; INFLAMMATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; SKIN EDEMA; SKIN TUMOR; TUMOR REGRESSION; TUMOR VOLUME;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMALS; ANTICARCINOGENIC AGENTS; APOPTOSIS; CHEMOPREVENTION; CYCLOOXYGENASE 2; DISEASE MODELS, ANIMAL; DRUG SCREENING ASSAYS, ANTITUMOR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FARNESOL; INFLAMMATION; MICE; ORNITHINE DECARBOXYLASE; OXIDATIVE STRESS; RAS PROTEINS; SKIN; SKIN NEOPLASMS; TETRADECANOYLPHORBOL ACETATE;

MURINAE; MUS;

EID: 67649791951     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2009.05.008     Document Type: Article

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