No effects of UMTS exposure on the function of rat outer hair cells

Bioelectromagnetics

Volumn 30, Issue 5, 2009, Pages 385-392

  Galloni, Paolo ^a,c   Lopresto, Vanni ^a   Parazzini, Marta ^b   Pinto, Rosanna ^a   Piscitelli, Marta ^a   Ravazzani, Paolo ^b   Marino, Carmela ^a  

^a ENEA C R CASACCIA   (Italy)

^b CNR   (Italy)

^c NONE   (Italy)

Author keywords

Cochlea; Mobile phones; Otoacoustic emissions; Radiofrequency; Rodents

Indexed keywords

ELECTROMAGNETIC FIELDS; RATS;

COCHLEA; COMMUNICATION DEVICE; DISTORTION PRODUCT; ELECTROMAGNETIC FIELD EXPOSURE; HUMAN HEALTH; KANAMYCINS; OUTER HAIR CELL; PUBLIC CONCERN; RADIOFREQUENCIES; RODENT;

OTOACOUSTIC EMISSIONS;

KANACILL FORTIUS; KANAMYCIN; UNCLASSIFIED DRUG;

ABSORPTION; ANIMAL EXPERIMENT; ARTICLE; AUDIOLOGY; CELL FUNCTION; CONTROLLED STUDY; DISTORTION PRODUCT OTOACOUSTIC EMISSION; ELECTROMAGNETIC FIELD; EXTERNAL AUDITORY CANAL; HAIR CELL; MALE; MOBILE PHONE; NONHUMAN; OTOTOXICITY; PRIORITY JOURNAL; RADIOFREQUENCY; RAT; STATISTICAL SIGNIFICANCE;

ANIMALIA; RATTUS; RODENTIA;

EID: 67649757503     PISSN: 01978462     EISSN: 1521186X     Source Type: Journal    
DOI: 10.1002/bem.20483     Document Type: Article

References (50)

1. Ahlbom A, Bridges J, de Seze R, Hillert L, Juutilainen J, Mattsson MO, Neubauer G, Schüz J, Simko M, Bromen K. 2008. Possible effects of electromagnetic fields (EMF) on human health - Opinion of the scientific committee on emerging and newly identified health risks (SCENIHR). Toxicology 246(2-3):248-250.
2. Arai N, Enomoto H, Okabe S, Yuasa K, Kamimura Y, Ugawa Y. 2003. Thirty minutes mobile phone use has no short-term adverse effects on central auditory pathways. Clin Neurophysiol 114(8):1390-1394. (Pubitemid 36897774)
3. Aran JM, Carrere N, Chalan Y, Dulou PE, Larrieu S, Letenneur L, Veyret B, Dulon D. 2004. Effects of exposure of the ear to GSM microwaves: In vivo and in vitro experimental studies. Int J Audiol 43:545-554.
4. Belyaev IY, Koch CB, Terenius O, Roxström-Lindquist K, Malmgren LO, Sommer WH, Salford LG, Persson BR. 2006. Exposure of rat brain to 915 MHz GSM microwaves induces changes in gene expression but not double stranded DNA breaks or effects on chromatin conformation. Bioelectromagnetics 27(4):295-306.
5. Berg G, Schuz J, Samkange-Zeeb F, Blettner M. 2005. Assessment of radio-frequency exposure from cellular telephone daily use in an epidemiological study: German validation study of the international case-control study of cancers of the brain - INTERPHONE-study. J Expo Anal Environ Epidemiol 15: 217-224. (Pubitemid 40791399)
6. Breckenkamp J, Berg G, Blettner M. 2003. Biological effects on human health due to radiofrequency/microwave exposure: A synopsis of cohort studies. Radiat Environ Biophys 42(3): 141-154. (Pubitemid 37518058)
7. Challis LJ. 2005. Mechanisms for interaction between RF fields and biological tissue. Bioelectromagnetics (Suppl 7):S98-S106. (Pubitemid 41510879)
8. Cotgreave A. 2005. Biological stress responses to radio frequency electromagnetic radiation: are mobile phones really so (heat) shocking? Arch Biochem Biophys 435:227-240. (Pubitemid 40170034)
9. Elder JA, Chou CK. 2003. Auditory response to pulsed radiofrequency energy. Bioelectromagnetics (Suppl 6):S162-S173. (Pubitemid 38622961)
10. Ferber-Viart C, Preckel MP, Dubreuil C, Banssillon V, Duclaux R. 1998. Effect of anesthesia on transient evoked otoacoustic emissions in humans: A comparison between propofol and isoflurane. Hear Res 121(1-2):53-61. (Pubitemid 28319897)
11. Feychting M, Ahlbom A, Kheifets L. 2005. EMF and health. Annu Rev Public Health 26:165-189. (Pubitemid 40547380)
12. Forge A, Schacht J. 2000. Aminoglycoside antibiotics. Audiol Neurootol 5:3-22. (Pubitemid 30093591)
13. Franke H, Streckert J, Bitz A, Goeke J, Hansen V, Ringelstein EB, Nattkämper H, Galla HJ, Stögbauer F. 2005. Effects of universal mobile telecommunications system (UMTS) electromagnetic fields on the blood-brain barrier in vitro. Radiat Res 164(3):258-269. (Pubitemid 41233779)
14. Fritze K, Wiessner C, Kuster N, Sommer C, Gass P, Hermann DM, Kiessling M, Hossmann KA. 1997. Effect of global system for mobile communication microwave exposure on the genomic response of the rat brain. Neuroscience 81(3): 627-639. (Pubitemid 27402511)
15. Galloni P, Lovisolo GA, Mancini S, Parazzini M, Pinto R, Piscitelli M, Ravazzani P, Marino C. 2005a. Effects of 900 MHz electromagnetic fields exposure on cochlear cells' functionality in rats: Evaluation of Distortion Product OtoAcoustic Emissions. Bioelectromagnetics 26(7):536-547. (Pubitemid 41437408)
16. Galloni P, Parazzini M, Piscitelli M, Pinto R, Lovisolo GA, Tognola G, Marino C, Ravazzani P. 2005b. Electromagnetic fields from mobile phones do not affect the inner auditory system of Sprague-Dawley rats. Radiat Res 164(6):798-804. (Pubitemid 41692727)
17. Guven S, Tas A, Adali MK, Yagiz R, Alagol A, Uzun C, Koten M, Karasalihoglu AR. 2006. Influence of anaesthetic agents on transient evoked otoacoustic emissions and stapedius reflex thresholds. J Laryngol Otol 120(1):10-15. (Pubitemid 46832899)
18. Hammernick RP, Ahroon WA, Hsueh KD, Lei SF, Davis RI. 1993. Audiometric and histological differences between the effects of continuous and impulsive noise exposure. J Acoust Soc Am 93:2088-2095. (Pubitemid 23110796)
19. Hardell L, Carlberg M, Mild KH. 2005. Case-control study on cellular and cordless telephones and the risk for acoustic neuroma or meningioma in patients diagnosed 2000-2003. Neuroepidemiology 25:120-128. (Pubitemid 41207064)
20. Hatzopoulos S, Di Stefano M, Albertin A, Martini A. 1999. Evaluation of cisplatin ototoxicity in a rat animal model. Ann NY Acad Sci 884:211-225.
21. Henley CM, Rybak LP. 1995. Ototoxicity in developing mammals. Brain Res Brain Res Rev 20(1):68-90.
22. 2 otoacoustic emissions in pigmented rats. Hear Res 43:141-148. (Pubitemid 20040493)
23. Himeno C, Komeda M, Izumikawa M, Takemura K, Yagi M, Weiping Y, Doi T, Kuriyama H, Miller JM, Yamashita T. 2002. Intra-cochlear administration of dexamethasone attenuates aminoglycoside ototoxicity in the guinea pig. Hear Res 67(1-2):61-70. (Pubitemid 34756851)
24. Huang TQ, Lee MS, Oh EH, Kalinec F, Zhang BT, Seo JS, Park WY. 2008. Characterization of biological effect of 1763 MHz radiofrequency exposure on auditory hair cells. Int J Radiat Biol. 84(11):909-915.
25. Inskip PD, Tarone RE, Hatch EE,Wilcosky TC, Shapiro WR, Selker RG, Fine HA, Black PM, Loeffler JS, Linet MS. 2001. Cellular telephone use and brain tumors. N Engl J Med 344:79-86. (Pubitemid 32052496)
26. Jiang H, Sha S-H, Forge A, Schacht J. 2006. Caspase-independent pathways of hair cell death induced by kanamycin in vivo. Cell Death Differ 13(1):20-30.
27. Kizilay A, Ozturan O, Erdem T, Kalcioglu MT, Miman MC. 2003. Effects of chronic exposure of electromagnetic fields from mobile phones on hearing in rats. Auris Nasus Larynx 30: 239-245. (Pubitemid 36966089)
28. Lin JC,Wang Z. 2007. Hearing of microwave pulses by humans and animals: effects, mechanism, and thresholds. Health Physics 92(6):621-628. (Pubitemid 46742944)
29. Lönn S, Ahlbom A, Hall P, Feychting M. 2004. Mobile phone use and the risk of acoustic neuroma. Epidemiology 15(6):653-659. (Pubitemid 40424544)
30. Lopresto V, Pinto R, De Vita A, Mancini S, Galloni P, Marino C, Ravazzani P, Lovisolo GA. 2007. Exposure setup to study potential adverse effects at GSM1800 and UMTS frequencies on the auditory systems of rats. Radiat Prot Dosimetry 123(4):473-482.
31. Moulder JE, Foster KR, Erdreich LS, McNamee JP. 2005. Mobile phones, mobile phone base stations and cancer: A review. Int J Radiat Biol 81:189-203. (Pubitemid 40911069)
32. Muscat JE, Malkin MG, Shore RE, Thompson S, Neugut AI, Stellman S, Bruce J. 2002. Handheld cellular telephones and risk of acoustic neuroma. Neurology 58:1304-1313. (Pubitemid 34411885)
33. New York Academy of Sciences, New York. 1988. Interdisciplinary principles and guidelines for the use of animals in research, testing, and education.
34. Oysu C, Topak M, Celik O, Yilmaz HB, Sahin AA. 2005. Effects of the acute exposure to the electromagnetic field of mobile phones on human auditory brainstem responses. Eur Arch Otorhinolaryngol 262(10):839-843. (Pubitemid 41605799)
35. Paglialonga A, Tognola G, Parazzini M, Lutman M, Bell SL, Thuroczy G, Ravazzani P. 2007. Effects of mobile phone exposure on time frequency fine structure of transiently evoked otoacoustic emissions. J Acoust Soc Am 122(4): 2174-2782. (Pubitemid 47493344)
36. Parazzini M, Bell S, Thuroczy G, Molnar F, Tognola G, Lutman ME, Ravazzani P. 2005. Influence on the mechanisms of generation of distortion product otoacoustic emissions of mobile phones exposure. Hear Res 208(1-2):68-78. (Pubitemid 41427130)
37. Parazzini M, Galloni P, Brazzale AR, Tognola G, Marino C, Ravazzani P. 2006. Quantitative indices for the assessment of the repeatability of distortion product otoacoustic emissions in laboratory animals. IEEE Trans Biomed Eng 53(8):1550-1556. (Pubitemid 44150266)
38. Parazzini M, Galloni P, Piscitelli M, Pinto R, Lovisolo GA, Tognola G, Ravazzani P, Marino C. 2007a. Possible combined effects of 900 MHz CW electromagnetic fields and gentamicin on the auditory system of rats. Radiat Res 167(5):600-605. (Pubitemid 351292967)
39. Parazzini M, Brazzale AR, Paglialonga A, Tognola G, Collet L, Moulin A, Lutman ME, Bell SL, Thomas NA, Uloziene I, Uloza V, Thuroczy G, Tavartkiladze G, Tsalighopoulos M, Kyriafinis G, Ravazzani P. 2007b. Effects of GSM cellular phones on human hearing: The European project "GUARD." Radiat Res 168:608-613.
40. Parazzini M, Tognola G, Franzoni C, Grandori F, Ravazzani P. 2007c. Modeling of the internal fields distribution in human inner hearing system exposed to 900 and 1800 MHz. IEEE Trans Biomed Eng 54(1):39-48. (Pubitemid 46127136)
41. Probst R, Lonsbury-Martin BL, Martin GK. 1991. A review of otoacoustic emissions. J Acoust Soc Am 89:2027-2067.
42. Sadetzki S, Chetrit A, Jarus-Hakak A, Cardis E, Deutch Y, Duvdevani S, Zultan A, Novikov I, Freedman L, Wolf M. 2008. Cellular phone use and risk of benign and malignant parotid gland tumors - A nationwide case-control study. Am J Epidemiol 167(4):457-467.
43. Schoemaker MJ, Swerdlow AJ, Ahlbom A, Auvinen A, Blaasaas KG, Cardis E, Christensen HC, Feychting M, Hepworth SJ, Johansen C, Klaeboe L, Lönn S, McKinney PA, Muir K, Raitanen J, Salminen T, Thomsen J, Tynes T. 2005. Mobile phone use and risk of acoustic neuroma: Results of the Interphone case-control study in five North European countries. Br J Cancer 93(7):842-848. (Pubitemid 41486448)
44. Seaman RL, Beblo DA. 1992. Modification of acoustic startle by microwave pulses in the rat: A preliminary report. Bioelectromagnetics 13(4):323-328.
45. Seaman RL, Lebovitz RM. 1987. Auditory unit responses to singlepulse and twin-pulse microwave stimuli. Hear Res 26:105-116. (Pubitemid 17006980)
46. Sienkiewicz Z, Jones N, Bottomley A. 2005. Neurobehavioural effects of electromagnetic fields. Bioelectromagnetics (Suppl 7):S116-S126. (Pubitemid 41510881)
47. Stefanics G, Kellényi L, Molnár F, Kubinyi G, Thuróczy G, Hernádi I. 2007. Short GSM mobile phone exposure does not alter human auditory brainstem response. BMC Public Health 7:325.
48. Uloziene I, Uloza V, Gradauskiene E, Saferis V. 2005. Assessment of potential effects of electromagnetic fields of mobile phones on hearing. BMC, Public Health 5:39. Avaliable from: http://www.biomedcentral.com/1471-2458/5/39. (Pubitemid 41006646)
49. Valberg PA, van Deventer TE, Repacholi MH. 2007. Workgroup report: Base station and wireless networks-Radiofrequency (RF) exposure and health consequences. Environ Health Perspect 115(3):416-424. (Pubitemid 46554441)
50. Wu WJ, Sha SH, Schacht J. 2002. Recent advances in understanding aminoglycoside ototoxicity and its prevention. Audiol Neurootol 7(3):171-174. (Pubitemid 34621569)