Effects of 900 MHz electromagnetic fields exposure on cochlear cells' functionality in rats: Evaluation of distortion Product OtoAcoustic Emissions

Bioelectromagnetics

Volumn 26, Issue 7, 2005, Pages 536-547

  Galloni, Paolo ^a   Lovisolo, Giorgio Alfonso ^a   Mancini, Sergio ^a   Parazzini, Marta ^b   Pinto, Rosanna ^a   Piscitelli, Marta ^a   Ravazzani, Paolo ^b   Marino, Carmela ^a  

^a ENEA C R CASACCIA   (Italy)

^b CNR   (Italy)

Author keywords

Cellular phone; DPOAE; Organ of corti; Outer hair cell; Radiofrequency

Indexed keywords

ACOUSTIC EMISSIONS; AUDITION; CELLULAR TELEPHONES; ELECTROMAGNETIC FIELDS;

900 MHZ; AUDITORY SYSTEMS; CELLULAR PHONE; DISTORTION PRODUCT OTOACOUSTIC EMISSIONS; ELECTROMAGNETIC FIELD EXPOSURE; HUMAN HEALTH; ORGAN OF CORTI; OUTER HAIR CELL; PUBLIC DEBATE; RADIOFREQUENCIES;

RATS;

AMPLITUDE MODULATION; ANIMAL CELL; ARTICLE; AUDITORY SYSTEM; CELL FUNCTION; COCHLEA; CORTI ORGAN; DISTORTION PRODUCT OTOACOUSTIC EMISSION; DOSIMETRY; ELECTROMAGNETIC FIELD; HAIR CELL; MICROWAVE RADIATION; MOBILE PHONE; NONHUMAN; PRIORITY JOURNAL; RADIATION EXPOSURE; RADIOFREQUENCY RADIATION; RAT;

EID: 26444461145     PISSN: 01978462     EISSN: None     Source Type: Journal    
DOI: 10.1002/bem.20127     Document Type: Article

References (51)

1. Adey WR, Byus CV, Cain CD, Higgins RJ, Jones RA, Kean CJ, Kuster N, MacMurray A, Stagg RB, Zimmerman G. 1999. Spontaneous and nitrosourea-induced primary tumors in Fischer 344 rats chronically exposed to 836 MHz modulated microwaves. Radiat Res 152:293-302.
2. Boice JD, McLaughlin JK. 2002. Epidemiologic studies of cellular telephones and cancer risk. Swedish Radiation Protection Authority, SSI Report, 2002:16.
3. Brownell WE. 1990. Outer hair cell electromotility and otoacoustic emissions. Ear Hear 11:82-92.
4. Brownell WE, Spector AA, Raphael RM, Popel AS. 2001. Micro- and nano-mechanics of the cochlear outer hair cell. Annu Rev Biomed Eng 3:69-94.
5. Cacace AT, McClelland WA, Weiner J, McFarland DJ. 1996. Individual differences and the reliability of 2F1-F2 distortion-product otoacustic emissions: Effects of time-of-day, stimulus variables, and gender. J Speech Hearing Res 39:1138-1148.
6. Chagnaud JL, Moreau JM, Veyret B. 1999. No effect of short-term exposure to GSM-modulated low-power microwaves on benzo(a)pyrene-induced tumors in rat. Int J Radiat Biol 75(10):1251-1256.
7. Chinn K, Brown OE, Manning SC, Crandell CC. 1997. Middle ear pressure variation: Effect of nitrous oxide. Laryngoscope 107(3):357-363.
8. Chou CK, Yee KC, Guy AW. 1985. Auditory response in rats exposed to 2,450 MHz electromagnetic fields in a circularly polarized waveguide. Bioelectromagnetics 6:323.
9. Chou CK, Chan KW, McDougall JA, Guy AW. 1999. Development of a rat head exposure system for simulating human exposure to RF fields from handheld wireless telephones. Bioelectromagnetics 20:75-92.
10. D'Andrea JA, Chou CK, Johnston SA, Adair ER. 2003. Microwave effects on the nervous system. Bioelectromagnetics Suppl 6:S107-147.
11. Davis B, Qiu W, Hamernik RP. 2004. The use of distortion product otoacoustic emissions in the estimation of hearing and sensory cell loss in noise-damaged cochleas. Hear Res 187:12-24.
12. Dulou PE, Faraone I, Vignéras V, Moreau JM, Hlavac R, Marino C, Lovisolo GA, Veyret B. 1998. Characterisation of new loop antennas operating at 900 and 1800 MHz for head-only exposure of rats and guinea pigs: Experimental measurements and FDTD calculations. Proceedings of BEMS. 152 p.
13. Elder JA, Chou CK. 2003. Auditory response to pulsed radiofrequency energy. Bioelectromagnetics Suppl 6:S162-S173.
14. Elwood JM. 2003. Epidemiological studies of radio frequency exposure and human cancer. Bioelecrtomagnetics Suppl 6:S63-S73.
15. European Commission Council. 1999. European Commission Council Recommendation of 12 July 1999 on the limitation of exposure of the general public to electromagnetic fields (0 Hz to 300 GHz)(1999/519/EC).
16. Fabijan DJ, Morris R, Murray GM. 2000. The effect of nitrous oxide on hearing. Anaesth Intensive Care 28(3):270-275.
17. Foster KR, Fynch ED, 1974. Microwave hearing; evidence for thermoacoustic auditory stimulation by pulsed microwaves. Science 185:256-258.
18. Frey AH. 1962. Human auditory system response to modulated electromagnetic energy. J Appl Physiol 17:689-692.
19. Guy AW, Chou CK, Lin JC, Christensen D. 1975. Microwave-induced acoustic effects in mammalian auditory systems and physical materials. Ann NY Acad Sci 247:194-218.
20. Hammernick RP, Ahroon WA, Hsueh KD, Lei SF, Davis RI. 1993. Audiometric ands histological differences between the effects of continuous and impulsive noise exposure. J Acoust Soc Am 93:2088-2095.
21. Hansson-Mild K, Hardell L, Kundi M, Mattsson MO. 2003. Mobile telephones and cancer: Is there really no evidence of an association? (review). Int J Mol Med 12(1):67-72.
22. Harel N, Nakigi A, Hirakawa H, Mount RJ, Harrison RV. 1997. The effects of anesthesia on otoacoustic emissions. Hear Res 110(1-2):25-33.
23. Hatzopoulos S, Di Stefano M, Campbell KC, Falgione D, Ricci D, Rosignoli M, Finesso M, Albertin A, Previati M, Capitani S, Martini A. 2001. Cisplatin ototoxicity in the Sprague-Dawley rat evaluated by distortion product otoacoustic emissions. Audiology 40(5):253-264.
24. Hatzopoulos S, Petruccelli J, Laurell G, Finesso M, Martini A. 2002. Evaluation of anesthesia effects in a rat animal model using otoacoustic emission protocols. Hear Res 170(1-2):12-21.
25. Hossmann KA, Hermann DM. 2003. Effects of electromagnetic radiation of mobile phones on the central nervous system. Bioelectromagnetics 24:49-62.
26. ICNIRP. 1998. Guidelines for limiting exposure to time-varying electric, magnetic and electromagnetic fields (up to 300 GHz). Health Physics 74:494-522.
27. ICNIRP. 2002. General Approach to Protection against Non Ionizing Radiation. Health Physics 82(4):540-548.
28. Kemp DT. 1978. Stimulated acoustic emissions from within the human auditory system. J Acoust Soc Am 64:1386-1391.
29. Kizilay A, Ozturan O, Erdem T, Kalcioglu MT, Miman MC. 2003. Effects of chronic exposure of electromagnetic fields from mobile phones n hearing in rats. Auris Naus Larynx 30:239-245.
30. Lai H, Singh NP. 1995. Acute low-intensity microwave exposure increases DNA single-strand breaks in rat brain cells. Bioelectromagnetics 16(3):207-210.
31. Le Calvez S, Avan P, Gilain L, Romand R. 1998. CD1 hearing-impaired mice. I: Distortion product otoacoustic emission levels, cochlear function and morphology. Hear Res 120:37-50.
32. Lenoir M, Fuel JL. 1987. Development of 2f1-f2 otoacoustic emissions in the rat. Hear Res 29:265-271.
33. Lin JC. 2002. Health aspects of wireless communication: Auditory perception of microwaves-Hearing microwaves. Mobile Comput Commun Review 6(2):9-12.
34. Lin JC. 2004. Studies on microwaves in medicine and biology: From snails to humans. Bioelectromagnetics 25:146-159.
35. Marino C, Cristalli G, Galloni P, Pasqualetti P, Piscitelli M, Lovisolo GA. 2000. Effects of microwaves (900 MHz) on the cochlear receptor: Exposure systems and preliminary results. Radiat Environ Biophys 39(2):131-136.
36. Mills CD, Loos BM, Henley CM. 1999. Increased susceptibility of male rats to kanamycin-induced cochleotoxicity. Hear Res 128(1-2):75-79.
37. NY Acad Sci. 1988. Interdisciplinary principles and guidelines for the use of animals in research, testing, and education. New York: Academy of Sciences.
38. Ozturan O, Erdem T, Miman MC, Kalcioglu MT, Oncel S. 2002. Effects of the electromagnetic field of mobile telephones on hearing. Acta Otolaryngol 122(3):289-293.
39. Pinto R, Mancini S, Ardoino L, Galloni P, Marino C, Lovisolo GA. 2003. Set-ups for biological activities at wireless communication frequencies. Proceeding of the 25th Annual Meeting of the Bioelectromagnetics Society, Wailea, Maui, HI, USA, June 22-26. 249 p.
40. Pouyatos B, Campo P, Lataye R. 2002. Use of DPOAEs for assessing hearing loss caused by styrene in the rat. Hear Res 165:156-164.
41. Probst R, Lonsbury-Martin BL, Martin GK. 1991. A review of otoacoustic emissions. J Acoust Soc Am 89(5):2027-2067.
42. Repacholi MH. 1998. Low-level exposure to radiofrequency electromagnetic fields: Health effects and research needs. Bioelectromagnetics 19(1):1-19.
43. Repacholi MH, Basten A, Gebski V, Noonan D, Finnie J, Harris AW. 1997. Lymphomas in E mu-Pim1 transgenic mice exposed to pulsed 900 MHZ electromagnetic fields. Radiat Res 147(5): 631-640.
44. Roede J, Harris FP, Probst R, Xu L. 1993. Repeatability of distortion product otoacoustic emissions in normally hearing humans. Audiology 32:273-281.
45. Salvi RJ, Ding D, Wang J, Jiang HY. 2000. A review of the effects of selective inner hair cell lesions on distortion product otoacoustic emissions, cochlear function and auditory evoked potentials. Noise Health 2(6):9-26.
46. Seaman RL, Beblo DA. 1992. Modification of acoustic startle by microwave pulses in the rat: A preliminary report. Bioelectromagnetics 13:323-328.
47. Sienkiewicz ZJ, Cridland NA, Kowalczuk CI, Saunder RD. 1993. Biological effects of electromagnetic fields and radiation. In: Stone WR, editor. The Review of Radio Science 1990-1992. New York: Oxford University Press. 737 p.
48. Sockalingam R, Freeman S, Cherny TL, Sohmer H. 2000. Effect of high-dose cisplatin on auditory brainstem responses and otoacoustic emissions in laboratory animals. Am J Otol 21(4):521-527.
49. Stewart W. 2000. IEGMP report, (ISBN 0-85951-450-1), NRPB, Mobile Phones and Health.
50. UNEP/WHO/IRPA. 1993. Electromagnetic Fields (300 Hz-300 GHz). Geneva, World Health Organization, Environmental Health Criteria 137.
51. Utteridge TD, Gebski V, Finnie JW, Vernon-Roberts B, Kuchel TR. 2002. Long-term exposure of Eμ-Pim1 transgenic mice to 898.4 MHz microwaves does not increase Lymphoma incidence. Radiat Res 158:357-364.