Evidence that phosphorylation of iron regulatory protein 1 at serine 138 destabilizes the [4Fe-4S] cluster in cytosolic aconitase by enhancing 4Fe-3Fe cycling

Journal of Biological Chemistry

Volumn 284, Issue 19, 2009, Pages 12701-12709

  Deck, Kathryn M ^a   Vasanthakumar, Aparna ^a   Anderson, Sheila A ^a   Goforth, Jeremy B ^a   Kennedy, M Claire ^b   Antholine, William E ^b   Eisenstein, Richard S ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACONITASE; ANAEROBIC CONDITIONS; CLUSTER REMOVAL; CYTOSOLIC ACONITASE; DEMETALLATION; HYPOXIC CONDITION; INTERCONVERSION; IRON AVAILABILITY; IRON CHELATION; IRON HOMEOSTASIS; IRON REGULATORY PROTEIN 1; IRON-SULFUR CLUSTERS; NON-OXIDATIVE; ORDER OF MAGNITUDE; RNA BINDING; SET-POINT;

AMINO ACIDS; CHELATION; LAWS AND LEGISLATION; NUCLEIC ACIDS; PHOSPHORYLATION; SULFUR;

RNA;

ACONITATE HYDRATASE; EDETIC ACID; IRON REGULATORY PROTEIN 1; NITRIC OXIDE; SERINE;

ARTICLE; CELL HYPOXIA; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HOMEOSTASIS; HUMAN; HUMAN CELL; IRON CHELATION; IRON SULFUR CLUSTER; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN PURIFICATION; PROTEIN RNA BINDING; PROTEIN STRUCTURE; REGULATORY MECHANISM;

ACONITATE HYDRATASE; ANOXIA; CYTOSOL; ELECTRON SPIN RESONANCE SPECTROSCOPY; HUMANS; IRON; IRON CHELATING AGENTS; IRON REGULATORY PROTEIN 1; IRON-SULFUR PROTEINS; KIDNEY; MUTAGENESIS, SITE-DIRECTED; MUTATION; NITRIC OXIDE; PHOSPHORYLATION; RNA; SERINE; SULFUR;

VERTEBRATA;

EID: 67649743469     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M807717200     Document Type: Article

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