Phenolic acids suppress adipocyte lipolysis via activation of the nicotinic acid receptor GPR109A (HM74a/PUMA-G)

Journal of Lipid Research

Volumn 50, Issue 5, 2009, Pages 908-914

  Ren, Ning ^a   Kaplan, Rebecca ^a   Hernandez, Melba ^a   Cheng, Kang ^a   Jin, Lan ^a   Taggart, Andrew K P ^a   Zhu, Amber Y ^a   Gan, Xiaodong ^a   Wright, Samuel D ^a   Cai, Tian Quan ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

GPCR; Niacin; Plant derived product

Indexed keywords

CINNAMIC ACID; FATTY ACID; HYDROCINNAMIC ACID; HYDROXYBENZOIC ACID; NICOTINIC ACID; NICOTINIC ACID RECEPTOR; PHENOL DERIVATIVE; PROTEIN GPR109A; RECEPTOR PROTEIN; UNCLASSIFIED DRUG; CINNAMIC ACID DERIVATIVE; G PROTEIN COUPLED RECEPTOR; GPR109A PROTEIN, HUMAN; GPR109B PROTEIN, MOUSE; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); HYDROXYBENZOIC ACID DERIVATIVE; NICOTINIC RECEPTOR; PHENOLIC ACID; PLANT EXTRACT;

ABDOMINAL FAT; ADIPOCYTE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOVASCULAR SYSTEM; CONTROLLED STUDY; DIETARY INTAKE; FOOD COMPOSITION; HUMAN; HUMAN CELL; LIPOLYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; RECEPTOR BINDING; WILD TYPE; ANIMAL; CELL CULTURE; CHEMICAL STRUCTURE; CHEMISTRY; CYTOLOGY; DRUG EFFECT; GENETICS; MALE; METABOLISM; MOUSE; MOUSE MUTANT; PHYSIOLOGY; RADIOASSAY;

ADIPOCYTES; ANIMALS; CELLS, CULTURED; CINNAMATES; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMANS; HYDROXYBENZOIC ACIDS; LIPOLYSIS; MALE; MICE; MICE, KNOCKOUT; MOLECULAR STRUCTURE; PLANT EXTRACTS; RADIOLIGAND ASSAY; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NICOTINIC;

EID: 67649682526     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M800625-JLR200     Document Type: Article

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