A monoclonal antibody with thyrotropin (TSH) receptor inverse agonist and TSH antagonist activities binds to the receptor hinge region as well as to the leucine-rich domain

Endocrinology

Volumn 150, Issue 7, 2009, Pages 3401-3408

  Chen, Chun Rong ^a   McLachlan, Sandra M ^a   Rapoport, Basil ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ANTIGEN; EPITOPE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CS 17; THYROTROPIN RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL TISSUE; ARTICLE; CHO CELL; FLOW CYTOMETRY; HINGE REGION; HORMONE BINDING; HORMONE STRUCTURE; MISMATCH REPAIR; MUTATION; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BINDING;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; CHO CELLS; CRICETINAE; CRICETULUS; EPITOPES; MICE; MODELS, MOLECULAR; MUTATION; POLYSACCHARIDES; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, THYROTROPIN; THYROTROPIN; TUNICAMYCIN;

EID: 67649670443     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2008-1800     Document Type: Article

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