Synthetic nonamer peptides derived from insect defensin mediate the killing of African trypanosomes in axenic culture

Parasitology Research

Volumn 105, Issue 1, 2009, Pages 217-225

  Kitani, Hiroshi ^a,b   Naessens, Jan ^c   Kubo, Masanori ^d   Nakamura, Yoshio ^d   Iraqi, Fuad ^c,e   Gibson, John ^c,f   Yamakawa, Minoru ^a  

^a NATIONAL INSTITUTE OF AGROBIOLOGICAL SCIENCES   (Japan)

^b JAPAN INTERNATIONAL RESEARCH CENTER FOR AGRICULTURAL SCIENCES   (Japan)

^c INTERNATIONAL LIVESTOCK RESEARCH INSTITUTE   (Kenya)

^d NATIONAL INSTITUTE OF ANIMAL HEALTH   (Japan)

^e TEL AVIV UNIVERSITY   (Israel)

^f UNIVERSITY OF NEW ENGLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

DEFENSIN; POLYPEPTIDE ANTIBIOTIC AGENT;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG EFFECT; ELECTRON MICROSCOPY; GERMFREE ANIMAL; MICROBIAL GROWTH; MOUSE; NONHUMAN; PARASITE ISOLATION; PEPTIDE ANALYSIS; PRIORITY JOURNAL; TRYPANOSOMA;

ANIMALS; CELL MEMBRANE; DEFENSINS; HUMANS; INSECTS; MICROBIAL VIABILITY; MICROSCOPY, ELECTRON, TRANSMISSION; OLIGOPEPTIDES; PARASITIC SENSITIVITY TESTS; TRYPANOCIDAL AGENTS; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMA CONGOLENSE;

HEXAPODA; MURINAE; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMA CONGOLENSE;

EID: 67649616178     PISSN: 09320113     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00436-009-1389-x     Document Type: Article

References (45)

1. S Aksoy 2003 Control of tsetse flies and trypanosomes using molecular genetics Vet Parasitol 115 125 145 (Pubitemid 37288947)
2. BM Anene DN Onah Y Nawa 2001 Drug resistance in pathogenic African trypanosomes: what hopes for the future? Vet Parasitol 96 83 100 (Pubitemid 32178416)
3. MP Barrett DW Boykin R Brun RR Tidwell 2007 Human African trypanosomiasis: pharmacological re-engagement with a neglected disease Br J Pharmacol 152 1155 1171 (Pubitemid 350242432)
4. HG Boman 1995 Peptide antibiotics and their role in innate immunity Annu Rev Immunol 13 61 92
5. N Boulanger RJ Munks JV Hamilton F Vovelle R Brun MJ Lehane P Bulet 2002 Epithelial innate immunity. A novel antimicrobial peptide with antiparasitic activity in the blood-sucking insect Stomoxys calcitrans J Biol Chem 277 49921 49926 (Pubitemid 36014441)
6. GD Brand JR Leite LP Silva S Albuquerque MV Prates RB Azevedo V Carregaro JS Silva VC Sa RA Brandao C Bloch Jr 2002 Dermaseptins from Phyllomedusa oreades and Phyllomedusa distincta. Anti-Trypanosoma cruzi activity without cytotoxicity to mammalian cells J Biol Chem 277 49332 49340 (Pubitemid 36014364)
7. KL Brown RE Hancock 2006 Cationic host defense (antimicrobial) peptides Curr Opin Immunol 18 24 30 (Pubitemid 43049644)
8. R Brun M Schonenberger 1979 Cultivation and in vitro cloning or procyclic culture forms of Trypanosoma brucei in a semi-defined medium. Short communication Acta Trop 36 289 292 (Pubitemid 10181444)
9. P Bulet C Hetru JL Dimarcq D Hoffmann 1999 Antimicrobial peptides in insects; structure and function Dev Comp Immunol 23 329 344 (Pubitemid 29309611)
10. H Chen Z Xu L Peng X Fang X Yin N Xu P Cen 2006 Recent advances in the research and development of human defensins Peptides 27 931 940
11. CE Clayton P Michels 1996 Metabolic compartmentation in African trypanosomes Parasitol Today 12 465 471 (Pubitemid 26390216)
12. MA Davitz AM Gurnett MG Low MJ Turner V Nussenzweig 1987 Decay-accelerating factor (DAF) shares a common carbohydrate determinant with the variant surface glycoprotein (VSG) of the African Trypanosoma brucei J Immunol 138 520 523 (Pubitemid 17002214)
13. T Ganz 2003 Defensins: antimicrobial peptides of innate immunity Nat Rev Immunol 3 710 720 (Pubitemid 41070812)
14. T Ganz RI Lehrer 1994 Defensins Curr Opin Immunol 6 584 589 (Pubitemid 24249516)
15. LR Haines RE Hancock TW Pearson 2003 Cationic antimicrobial peptide killing of African trypanosomes and Sodalis glossinidius, a bacterial symbiont of the insect vector of sleeping sickness Vector Borne Zoonotic Dis 3 175 186
16. RE Hancock HG Sahl 2006 Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies Nat Biotechnol 24 1551 1557
17. A Hemphill D Lawson T Seebeck 1991 The cytoskeletal architecture of Trypanosoma brucei J Parasitol 77 603 612
18. H Hirumi K Hirumi 1991 In vitro cultivation of Trypanosoma congolense bloodstream forms in the absence of feeder cell layers Parasitology 102 225 236
19. H Hirumi K Hirumi 1994 Axenic culture of African trypanosome bloodstream forms Parasitol Today 10 80 84 (Pubitemid 24052922)
20. JA Hoffmann FC Kafatos CA Janeway RA Ezekowitz 1999 Phylogenetic perspectives in innate immunity Science 284 1313 1318 (Pubitemid 29289650)
21. Y Hu S Aksoy 2005 An antimicrobial peptide with trypanocidal activity characterized from Glossina morsitans morsitans Insect Biochem Mol Biol 35 105 115
22. J Ishibashi H Saido-Sakanaka J Yang A Sagisaka M Yamakawa 1999 Purification, cDNA cloning and modification of a defensin from the coconut rhinoceros beetle, Oryctes rhinoceros Eur J Biochem 266 616 623
23. T Iwasaki H Saido-Sakanaka A Asaoka D Taylor J Ishibashi M Yamakawa 2007 In vitro activity of diasterometic antimicrobial peptides alone and in combination with antibiotics against methicillin-resitant Staphylococcus aureus and Pseudomonas aeruginosa J Insect Biotechnol Sericology 76 25 29 (Pubitemid 46464119)
24. RW Jack JR Tagg B Ray 1995 Bacteriocins of gram-positive bacteria Microbiol Rev 59 171 200
25. J Keiser A Stich C Burri 2001 New drugs for the treatment of human African trypanosomiasis: research and development Trends Parasitol 17 42 49 (Pubitemid 32012413)
26. PG Kennedy 2004 Human African trypanosomiasis of the CNS: current issues and challenges J Clin Invest 113 496 504 (Pubitemid 38542496)
27. H Kitani SJ Black Y Nakamura J Naessens NB Murphy Y Yokomizo J Gibson F Iraqi 2002 Recombinant tumor necrosis factor alpha does not inhibit the growth of African trypanosomes in axenic cultures Infect Immun 70 2210 2214 (Pubitemid 34242225)
28. Y Koyama M Motobu K Hikosaka M Yamada K Nakamura H Saido-Sakanaka A Asaoka M Yamakawa T Isobe K Shimura CB Kang H Hayashidani Y Nakai Y Hirota 2006 Cytotoxicity and antigenicity of antimicrobial synthesized peptides derived from the beetle Allomyrina dichotoma defensin in mice Int Immunopharmacol 6 1748 1753 (Pubitemid 44344537)
29. N Kuboki N Yokoyama N Kojima T Sakurai N Inoue C Sugimoto 2006 Efficacy of dipalmitoylphosphatidylcholine liposome against African trypanosomes J Parasitol 92 389 393
30. MM Kulkarni WR McMaster E Kamysz W Kamysz DM Engman BS McGwire 2006 The major surface-metalloprotease of the parasitic protozoan, Leishmania, protects against antimicrobial peptide-induced apoptotic killing Mol Microbiol 62 1484 1497
31. FA Kuzoe 1993 Current situation of African trypanosomiasis Acta Trop 54 153 162 (Pubitemid 23306680)
32. G Lalmanach A Boulange C Serveau F Lecaille J Scharfstein F Gauthier E Authie 2002 Congopain from Trypanosoma congolense: drug target and vaccine candidate Biol Chem 383 739 749 (Pubitemid 34649892)
33. RI Lehrer T Ganz 1999 Antimicrobial peptides in mammalian and insect host defence Curr Opin Immunol 11 23 27 (Pubitemid 29082332)
34. MN Madison YY Kleshchenko PN Nde KJ Simmons MF Lima F Villalta 2007 Human defensin a-1 causes Trypanosoma cruzi membrane pore formation and induces DNA fragmentation, which leads to trypanosome destruction Infect Immun 75 4780 4791 (Pubitemid 47502147)
35. JJ McDermott PG Coleman 2001 Comparing apples and oranges-model-based assessment of different tsetse-transmitted trypanosomosis control strategies Int J Parasitol 31 603 609 (Pubitemid 32382062)
36. BS McGwire CL Olson BF Tack DM Engman 2003 Killing of African trypanosomes by antimicrobial peptides J Infect Dis 188 146 152 (Pubitemid 36829755)
37. J Naessens AJ Teale M Sileghem 2002 Identification of mechanisms of natural resistance to African trypanosomiasis in cattle Vet Immunol Immunopathol 87 187 194 (Pubitemid 34665237)
38. AJ Nok GC Njoku E Balogun 2002 A 45-kDa midgut glycoprotein from Anopheles albimanus mosquito mediates the killing of trypanosomes Cell Biochem Funct 20 257 262
39. H Saido-Sakanaka J Ishibashi A Sagisaka E Momotani M Yamakawa 1999 Synthesis and characterization of bactericidal oligopeptides designed on the basis of an insect anti-bacterial peptide Biochem J 338 29 33 (Pubitemid 29097281)
40. H Saido-Sakanaka J Ishibashi E Momotani F Amano M Yamakawa 2004 In vitro and in vivo activity of antimicrobial peptides synthesized based on the insect defensin Peptides 25 19 27 (Pubitemid 38299283)
41. A Stich MP Barrett S Krishna 2003 Waking up to sleeping sickness Trends Parasitol 19 195 197 (Pubitemid 36588588)
42. A Treumann N Zitzmann A Hulsmeier AR Prescott A Almond J Sheehan MA Ferguson 1997 Structural characterisation of two forms of procyclic acidic repetitive protein expressed by procyclic forms of Trypanosoma brucei J Mol Biol 269 529 547 (Pubitemid 27267867)
43. MJ Vreysen 2001 Principles of area-wide integrated tsetse fly control using the sterile insect technique Med Trop (Mars) 61 397 411 (Pubitemid 33630387)
44. D Yang A Biragyn LW Kwak JJ Oppenheim 2002 Mammalian defensins in immunity: more than just microbicidal Trends Immunol 23 291 296 (Pubitemid 34628771)
45. MR Yeaman NY Yount 2003 Mechanisms of antimicrobial peptide action and resistance Pharmacol Rev 55 27 55 (Pubitemid 36268398)