-
1
-
-
41349099104
-
Cancer statistics, 2008
-
Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2008. CA Cancer J Clin 2008;58:71-96
-
(2008)
CA Cancer J Clin
, vol.58
, pp. 71-96
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
-
2
-
-
0037050352
-
Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer
-
DOI 10.1056/NEJMoa011954
-
Schiller JH, Harrington D, Belani CP, et al. Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer. N Engl J Med 2002;346:92-98 (Pubitemid 34438899)
-
(2002)
New England Journal of Medicine
, vol.346
, Issue.2
, pp. 92-98
-
-
Schiller, J.H.1
Harrington, D.2
Belani, C.P.3
Langer, C.4
Sandler, A.5
Krook, J.6
Zhu, J.7
Johnson, D.H.8
-
3
-
-
0034950354
-
Molecular genetic abnormalities in the pathogenesis of human lung cancer
-
Forgacs E, Zochbauer-Muller S, Olah E, et al. Molecular genetic abnormalities in the pathogenesis of human lung cancer. Pathol Oncol Res 2001;7:6-13 (Pubitemid 32591661)
-
(2001)
Pathology Oncology Research
, vol.7
, Issue.1
, pp. 6-13
-
-
Forgacs, E.1
Zochbauer-Muller, S.2
Olah, E.3
Minna, J.D.4
-
4
-
-
3042665905
-
Cyclooxygenase as a target in lung cancer
-
DOI 10.1158/1078-0432.CCR-040014
-
Brown JR, Dubois RN. Cyclooxygenase a target in lung cancer. Clin Cancer Res 2004;10(Suppl.):4266-4269 (Pubitemid 38812460)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.12 II
-
-
Brown, J.R.1
Dubois, R.N.2
-
5
-
-
33744471666
-
The potential and rationale for COX-2 inhibitors in lung cancer
-
Krysan K, Reckamp KL, Sharma S, et al. The potential and rationale for COX-2 inhibitors in lung cancer. Anticancer Agents Med Chem 2006;6:209-220 (Pubitemid 43796639)
-
(2006)
Anti-Cancer Agents in Medicinal Chemistry
, vol.6
, Issue.3
, pp. 209-220
-
-
Krysan, K.1
Reckamp, K.L.2
Sharma, S.3
Dubinett, S.M.4
-
6
-
-
29244449354
-
Prostaglandins and cancer
-
DOI 10.1136/gut.2004.047100
-
Wang D, Dubois RN. Prostaglandins and cancer. Gut 2006;55:115-122 (Pubitemid 41820645)
-
(2006)
Gut
, vol.55
, Issue.1
, pp. 115-122
-
-
Wang, D.1
Dubois, R.N.2
-
7
-
-
0037652234
-
Immunohistochemical expression of cyclooxygenase isoenzymes and downstream enzymes in human lung tumors
-
Ermert L, Dierkes C, Ermert M. Immunohistochemical expression of cyclooxygenase isoenzymes and downstream enzymes in human lung tumors. Clin Cancer Res 2003;9:1604-1610 (Pubitemid 36554582)
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.5
, pp. 1604-1610
-
-
Ermert, L.1
Dierkes, C.2
Ermert, M.3
-
8
-
-
0032170955
-
Increased expression of cyclooxygenase 2 occurs frequently in human lung cancers, specifically in adenocarcinomas
-
Hida T, Yatabe Y, Achiwa H, et al. Increased expression of cyclooxygenase 2 occurs frequently in human lung cancers, specifically in adenocarcinomas. Cancer Res 1998;58:3761-3764 (Pubitemid 28405625)
-
(1998)
Cancer Research
, vol.58
, Issue.17
, pp. 3761-3764
-
-
Hida, T.1
Yatabe, Y.2
Achiwa, H.3
Muramatsu, H.4
Kozaki, K.-I.5
Nakamura, S.6
Ogawa, M.7
Mitsudomi, T.8
Sugiura, T.9
Takahashi, T.10
-
9
-
-
0034671806
-
COX-2 is expressed in human pulmonary, colonic, and mammary tumors
-
DOI 10.1002/1097-0142(20001215)89:12<2637::AID-CNCR17>3.0.CO;2-B
-
Soslow RA, Dannenberg AJ, Rush D, et al. COX-2 is expressed in human pulmonary, colonic, and mammary tumors. Cancer 2000;89:2637-2645 (Pubitemid 32011609)
-
(2000)
Cancer
, vol.89
, Issue.12
, pp. 2637-2645
-
-
Soslow, R.A.1
Dannenberg, A.J.2
Rush, D.3
Woerner, B.M.4
Nasir Khan, K.5
Masferrer, J.6
Koki, A.T.7
-
10
-
-
0032533858
-
Expression of cyclooxygenase-2 in human lung carcinoma
-
Wolff H, Saukkonen K, Anttila S, et al. Expression of cyclooxygenase-2 in human lung carcinoma. Cancer Res 1998;58:4997-5001 (Pubitemid 28521147)
-
(1998)
Cancer Research
, vol.58
, Issue.22
, pp. 4997-5001
-
-
Wolff, H.1
Saukkonen, K.2
Anttila, S.3
Karjalainen, A.4
Vainio, H.5
Ristimaki, A.6
-
11
-
-
0036191910
-
Prognostic significance of cyclooxygenase 2 mRNA expression in non-small cell lung cancer
-
DOI 10.1097/00000658-200203000-00017
-
Brabender J, Park J, Metzger R, et al. Prognostic significance of cyclooxygenase 2 mRNA expression in non-small cell lung cancer. Ann Surg 2002;235:440-443 (Pubitemid 34183896)
-
(2002)
Annals of Surgery
, vol.235
, Issue.3
, pp. 440-443
-
-
Brabender, J.1
Park, J.2
Metzger, R.3
Schneider, P.M.4
Lord, R.V.5
Holscher, A.H.6
Danenberg, K.D.7
Danenberg, P.V.8
-
12
-
-
0034901568
-
Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer
-
Khuri FR, Wu H, Lee JJ, et al. Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer. Clin Cancer Res 2001;7:861-867 (Pubitemid 32708722)
-
(2001)
Clinical Cancer Research
, vol.7
, Issue.4
, pp. 861-867
-
-
Khuri, F.R.1
Wu, H.2
Lee, J.J.3
Kemp, B.L.4
Lotan, R.5
Lippman, S.M.6
Feng, L.7
Hong, W.K.8
Xu, X.-C.9
-
13
-
-
24344494462
-
Prognostic significance of cyclooxygenase 2 expression in 259 cases of non-small cell lung cancer
-
Laga AC, Zander DS, Cagle PT. Prognostic significance of cyclooxygenase 2 expression in 259 cases of non-small cell lung cancer. Arch Pathol Lab Med 2005;129:1113-1117 (Pubitemid 41244809)
-
(2005)
Archives of Pathology and Laboratory Medicine
, vol.129
, Issue.9
, pp. 1113-1117
-
-
Laga, A.C.1
Zander, D.S.2
Cagle, P.T.3
-
14
-
-
0024517117
-
Prostaglandin H synthase-dependent mutagenic activation of benzidine in a Salmonella typhimurium Ames tester strain possessing elevated N-acetyltransferase levels
-
Josephy PD, Chiu AL, Eling TE. Prostaglandin H synthase-dependent mutagenic activation of benzidine in a Salmonella typhimurium Ames tester strain possessing elevated N-acetyltransferase levels. Cancer Res 1989;49:853-856 (Pubitemid 19064335)
-
(1989)
Cancer Research
, vol.49
, Issue.4
, pp. 853-856
-
-
Josephy, P.D.1
Chiu, A.L.H.2
Eling, T.E.3
-
15
-
-
0031427096
-
Benzo[a]pyrene up-regulates cyclooxygenase-2 gene expression in oral epithelial cells
-
DOI 10.1093/carcin/18.4.795
-
Kelley DJ, Mestre JR, Subbaramaiah K, et al. Benzo[a]pyrene up-regulates cyclooxygenase-2 gene expression in oral epithelial cells. Carcinogenesis 1997;18:795-799 (Pubitemid 28132470)
-
(1997)
Carcinogenesis
, vol.18
, Issue.4
, pp. 795-799
-
-
Kelley, D.J.1
Mestre, J.R.2
Subbaramaiah, K.3
Sacks, P.G.4
Schantz, S.P.5
Tanabe, T.6
Inoue, H.7
Ramonetti, J.T.8
Dannenberg, A.J.9
-
16
-
-
19944432973
-
Levels of cyclooxygenase-2 are increased in the oral mucosa of smokers: Evidence for the role of epidermal growth factor receptor and its ligands
-
Moraitis D, Du B, De Lorenzo MS, et al. Levels of cyclooxygenase-2 are increased in the oral mucosa of smokers: evidence for the role of epidermal growth factor receptor and its ligands. Cancer Res 2005;65:664-670
-
(2005)
Cancer Res
, vol.65
, pp. 664-670
-
-
Moraitis, D.1
Du, B.2
De Lorenzo, M.S.3
-
17
-
-
0034161878
-
Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors
-
Masferrer JL, Leahy KM, Koki AT, et al. Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors. Cancer Res 2000;60:1306-1311 (Pubitemid 30151999)
-
(2000)
Cancer Research
, vol.60
, Issue.5
, pp. 1306-1311
-
-
Masferrer, J.L.1
Leahy, K.M.2
Koki, A.T.3
Zweifel, B.S.4
Settle, S.L.5
Woerner, B.M.6
Edwards, D.A.7
Flickinger, A.G.8
Moore, R.J.9
Seibert, K.10
-
18
-
-
0032405901
-
Meloxicam inhibits the growth of colorectal cancer cells
-
DOI 10.1093/carcin/19.12.2195
-
Goldman AP, Williams CS, Sheng H, et al. Meloxicam inhibits the growth of colorectal cancer cells. Carcinogenesis 1998;19:2195-2199 (Pubitemid 29010262)
-
(1998)
Carcinogenesis
, vol.19
, Issue.12
, pp. 2195-2199
-
-
Goldman, A.P.1
Williams, C.S.2
Sheng, H.3
Lamps, L.W.4
Williams, V.P.5
Pairet, M.6
D.morrow, J.7
Dubois, R.N.8
-
19
-
-
0034026144
-
Cyclooxygenase-2 inhibitor induces apoptosis and enhances cytotoxicity of various anticancer agents in non-small cell lung cancer cell lines
-
Hida T, Kozaki K, Muramatsu H, et al. Cyclooxygenase-2 inhibitor induces apoptosis and enhances cytotoxicity of various anticancer agents in non-small cell lung cancer cell lines. Clin Cancer Res 2000;6:2006-2011 (Pubitemid 30305099)
-
(2000)
Clinical Cancer Research
, vol.6
, Issue.5
, pp. 2006-2011
-
-
Hida, T.1
Kozaki, K.-I.2
Muramatsu, H.3
Masuda, A.4
Shimizu, S.5
Mitsudomi, T.6
Sugiura, T.7
Ogawa, M.8
Takahashi, T.9
-
20
-
-
0035992439
-
Significant growth inhibition of human lung cancer cells both in vitro and in vivo by the combined use of a selective cyclooxygenase 2 inhibitor, JTE-522, and conventional anticancer agents
-
Hida T, Kozaki K-I, Ito H, et al. Significant growth inhibition of human lung cancer cells both in vitro and in vivo by the combined use of a selective cyclooxygenase 2 inhibitor, JTE-522, and conventional anticancer agents. Clin Cancer Res 2002;8:2443-2447
-
(2002)
Clin Cancer Res
, vol.8
, pp. 2443-2447
-
-
Hida, T.1
Kozaki, K.-I.2
Ito, H.3
-
21
-
-
0030947525
-
Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2
-
Sheng H, Shao J, Kirkland SC, et al. Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2. J Clin Invest 1997;99:2254-2259 (Pubitemid 27203783)
-
(1997)
Journal of Clinical Investigation
, vol.99
, Issue.9
, pp. 2254-2259
-
-
Sheng, H.1
Shao, J.2
Kirkland, S.C.3
Isakson, P.4
Coffey, R.J.5
Morrow, J.6
Beaucnamp, R.D.7
Dubois, R.N.8
-
22
-
-
0034089566
-
Host cyclooxygenase-2 modulates carcinoma growth
-
Williams CS, Tsujii M, Reese J, et al. Host cyclooxygenase-2 modulates carcinoma growth [see comments]. J Clin Invest 2000;105:1589-1594 (Pubitemid 30390309)
-
(2000)
Journal of Clinical Investigation
, vol.105
, Issue.11
, pp. 1589-1594
-
-
Williams, C.S.1
Tsujii, M.2
Reese, J.3
Dey, S.K.4
Dubois, R.N.5
-
23
-
-
64049107388
-
A randomized double-blind study of the biological effects of celecoxib as a chemopreventive agent in current and former smokers
-
Kim ES, Hong WK, Lee JJ, et al. A randomized double-blind study of the biological effects of celecoxib as a chemopreventive agent in current and former smokers. J Clin Oncol 2008;26:1501
-
(2008)
J Clin Oncol
, vol.26
, pp. 1501
-
-
Kim, E.S.1
Hong, W.K.2
Lee, J.J.3
-
24
-
-
17744418769
-
The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis
-
DOI 10.1056/NEJM200006293422603
-
Steinbach G, Lynch PM, Phillips RK, et al. The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis. N Engl J Med 2000;342:1946-1952 (Pubitemid 30419089)
-
(2000)
New England Journal of Medicine
, vol.342
, Issue.26
, pp. 1946-1952
-
-
Steinbach, G.1
Lynch, P.M.2
Phillips, R.K.S.3
Wallace, M.H.4
Hawk, E.5
Gordon, G.B.6
Wakabayashi, N.7
Saunders, B.8
Shen, Y.9
Fujimura, T.10
Su, L.-K.11
Levin, B.12
Godio, L.13
Patterson, S.14
Rodriguez-Bigas, M.A.15
Jester, S.L.16
King, K.L.17
Schumacher, M.18
Abbruzzese, J.19
Dubois, R.N.20
Hittelman, W.N.21
Zimmerman, S.22
Sherman, J.W.23
Kelloff, G.24
more..
-
25
-
-
34249673868
-
Aspirin and the risk of colorectal cancer in relation to the expression of COX-2
-
DOI 10.1056/NEJMoa067208
-
Chan AT, Ogino S, Fuchs CS. Aspirin and the risk of colorectal cancer in relation to the expression of COX-2. N Engl J Med 2007;356:2131-2142 (Pubitemid 47010839)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.21
, pp. 2131-2142
-
-
Chan, A.T.1
Ogino, S.2
Fuchs, C.S.3
-
26
-
-
34249320128
-
Factorial phase III randomised trial of rofecoxib and prolonged constant infusion of gemcitabine in advanced non-small-cell lung cancer: The GEmcitabine-COxib in NSCLC (GECO) study
-
DOI 10.1016/S1470-2045(07)70146-8, PII S1470204507701468
-
Gridelli C, Gallo C, Ceribelli A, et al. Factorial phase III randomised trial of rofecoxib and prolonged constant infusion of gemcitabine in advanced non-small-cell lung cancer: the GEmcitabine-COxib in NSCLC (GECO) study. Lancet Oncol 2007;8:500-512 (Pubitemid 46805905)
-
(2007)
Lancet Oncology
, vol.8
, Issue.6
, pp. 500-512
-
-
Gridelli, C.1
Gallo, C.2
Ceribelli, A.3
Gebbia, V.4
Gamucci, T.5
Ciardiello, F.6
Carozza, F.7
Favaretto, A.8
Daniele, B.9
Galetta, D.10
Barbera, S.11
Rosetti, F.12
Rossi, A.13
Maione, P.14
Cognetti, F.15
Testa, A.16
Di Maio, M.17
Morabito, A.18
Perrone, F.19
-
27
-
-
55749105531
-
Cardiovascular events associated with rofecoxib: Final analysis of the APPROVe trial
-
Baron JA, Sandler RS, Bresalier RS, et al. Cardiovascular events associated with rofecoxib: final analysis of the APPROVe trial. Lancet 2008;372:1756-1764
-
(2008)
Lancet
, vol.372
, pp. 1756-1764
-
-
Baron, J.A.1
Sandler, R.S.2
Bresalier, R.S.3
-
28
-
-
39749149266
-
Eicosanoid modulation in advanced lung cancer: Cyclooxygenase-2 expression is a positive predictive factor for celecoxib + chemotherapy
-
Cancer and Leukemia Group B Trial 30203
-
Edelman MJ, Watson D, Wang X, et al. Eicosanoid modulation in advanced lung cancer: cyclooxygenase-2 expression is a positive predictive factor for celecoxib + chemotherapy. Cancer and Leukemia Group B Trial 30203. J Clin Oncol 2008;26:848-855
-
(2008)
J Clin Oncol
, vol.26
, pp. 848-855
-
-
Edelman, M.J.1
Watson, D.2
Wang, X.3
-
30
-
-
0030023776
-
Growth control of lung cancer by interruption of 5-lipoxygenase-mediated growth factor signaling
-
Avis IM, Jett M, Boyle T, et al. Growth control of lung cancer by interruption of 5-lipoxygenase-mediated growth factor signaling. J Clin Invest 1996;97:806-813 (Pubitemid 26057100)
-
(1996)
Journal of Clinical Investigation
, vol.97
, Issue.3
, pp. 806-813
-
-
Avis, I.M.1
Jett, M.2
Boyle, T.3
Vos, M.D.4
Moody, T.5
Treston, A.M.6
Martinez, A.7
Mulshine, J.L.8
-
31
-
-
0031705797
-
Inhibitors of lipoxygenase: A new class of cancer chemopreventive agents
-
DOI 10.1093/carcin/19.8.1393
-
Rioux N, Castonguay A. Inhibitors of lipoxygenase: a new class of cancer chemopreventive agents. Carcinogenesis 1998;19:1393-1400 (Pubitemid 28409837)
-
(1998)
Carcinogenesis
, vol.19
, Issue.8
, pp. 1393-1400
-
-
Rioux, N.1
Castonguay, A.2
-
32
-
-
0042413836
-
Randomized, multinational, phase III study of docetaxel plus platinum combinations versus vinorelbine plus cisplatin for advanced non-small-cell lung cancer: The TAX 326 Study Group
-
DOI 10.1200/JCO.2003.12.046
-
Fossella F, Pereira JR, von Pawel J, et al. Randomized, multinational, phase III study of docetaxel plus platinum combinations versus vinorelbine plus cisplatin for advanced non-small-cell lung cancer: the TAX 326 study group. J Clin Oncol 2003;21:3016-3024 (Pubitemid 46606280)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.16
, pp. 3016-3024
-
-
Fossella, F.1
Pereira, J.R.2
Von Pawel, J.3
Pluzanska, A.4
Gorbounova, V.5
Kaukel, E.6
Mattson, K.V.7
Ramlau, R.8
Szczesna, A.9
Fidias, P.10
Millward, M.11
Belani, C.P.12
-
33
-
-
0035397994
-
Randomized phase III trial of paclitaxel plus carboplatin versus vinorelbine plus cisplatin in the treatment of patients with advanced non-small-cell lung cancer: A Southwest Oncology Group trial
-
Kelly K, Crowley J, Bunn PA, et al. Randomized phase III trial of paclitaxel plus carboplatin versus vinorelbine plus cisplatin in the treatment of patients with advanced non-small-cell lung cancer: a Southwest Oncology Group trial. J Clin Oncol 2001;19:3210-3218 (Pubitemid 32591438)
-
(2001)
Journal of Clinical Oncology
, vol.19
, Issue.13
, pp. 3210-3218
-
-
Kelly, K.1
Crowley, J.2
Bunn Jr., P.A.3
Presant, C.A.4
Grevstad, P.K.5
Moinpour, C.M.6
Ramsey, S.D.7
Wozniak, A.J.8
Weiss, G.R.9
Moore, D.F.10
Israel, V.K.11
Livingston, R.B.12
Gandara, D.R.13
-
34
-
-
0032948381
-
Prognostic significance of elevated cyclooxygenase 2 expression in primary, resected lung adenocarcinomas
-
Achiwa H, Yatabe Y, Hida T, et al. Prognostic significance of elevated cyclooxygenase 2 expression in primary, resected lung adenocarcinomas. Clin Cancer Res 1999;5:1001-1005 (Pubitemid 29233213)
-
(1999)
Clinical Cancer Research
, vol.5
, Issue.5
, pp. 1001-1005
-
-
Achiwa, H.1
Yatabe, Y.2
Hida, T.3
Kuroishi, T.4
Kozaki, K.-I.5
Nakamura, S.6
Ogawa, M.7
Sugiura, T.8
Mitsudomi, T.9
Takahashi, T.10
-
35
-
-
58949100556
-
Phase II study of docetaxel and celecoxib, a cyclooxygenase-2 inhibitor, in elderly or poor performance status (PS2) patients with advanced non-small cell lung cancer
-
Gadgeel SM, Wozniak A, Ruckdeschel JC, et al. Phase II study of docetaxel and celecoxib, a cyclooxygenase-2 inhibitor, in elderly or poor performance status (PS2) patients with advanced non-small cell lung cancer. J Thorac Oncol 2008;3:1293-1300
-
(2008)
J Thorac Oncol
, vol.3
, pp. 1293-1300
-
-
Gadgeel, S.M.1
Wozniak, A.2
Ruckdeschel, J.C.3
-
37
-
-
2442661845
-
Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy
-
DOI 10.1200/JCO.2004.08.163
-
Hanna N, Shepherd FA, Fossella FV, et al. Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy. J Clin Oncol 2004;22:1589-1597 (Pubitemid 41079796)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.9
, pp. 1589-1597
-
-
Hanna, N.1
Shepherd, F.A.2
Fossella, F.V.3
Pereira, J.R.4
Demarinis, F.5
Von Pawel, J.6
Gatzemeier, U.7
Tsao, T.C.Y.8
Pless, M.9
Muller, T.10
Lim, H.-L.11
Desch, C.12
Szondy, K.13
Gervais, R.14
Shaharyar15
Manegold, C.16
Paul, S.17
Paoletti, P.18
Einhorn, L.19
Bunn Jr., P.A.20
more..
-
38
-
-
0034069620
-
Prospective randomized trial of docetaxel versus best supportive care in patients with non-small-cell lung cancer previously treated with platinum- Based chemotherapy
-
Shepherd FA, Dancey J, Ramlau R, et al. Prospective randomized trial of docetaxel versus best supportive care in patients with non-small-cell lung cancer previously treated with platinum-based chemotherapy. J Clin Oncol 2000;18:2095-2103 (Pubitemid 30324363)
-
(2000)
Journal of Clinical Oncology
, vol.18
, Issue.10
, pp. 2095-2103
-
-
Shepherd, F.A.1
Dancey, J.2
Ramlau, R.3
Mattson, K.4
Gralla, R.5
O'Rourke, M.6
Levitan, N.7
Gressot, L.8
Vincent, M.9
Burkes, R.10
Coughlin, S.11
Kim, Y.12
Berille, J.13
-
39
-
-
18244364810
-
Update of a phase I/II trial of carboplatin/ gemcitabine plus escalating doses of celecoxib for first-line treatment of stage IIIB/IV non-small cell lung cancer (NSCLC)
-
Burton JD, Badine E, El-Sayah D, et al. Update of a phase I/II trial of carboplatin/ gemcitabine plus escalating doses of celecoxib for first-line treatment of stage IIIB/IV non-small cell lung cancer (NSCLC). J Clin Oncol 2004;22:7339
-
(2004)
J Clin Oncol
, vol.22
, pp. 7339
-
-
Burton, J.D.1
Badine, E.2
El-Sayah, D.3
-
40
-
-
6044278144
-
Evaluating the efficiency of targeted designs for randomized clinical trials
-
DOI 10.1158/1078-0432.CCR-04-0496
-
Simon R, Maitournam A. Evaluating the efficiency of targeted designs for randomized clinical trials. Clin Cancer Res 2004;10:6759-6763 (Pubitemid 39383023)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.20
, pp. 6759-6763
-
-
Simon, R.1
Maitournam, A.2
-
41
-
-
0042631411
-
Celecoxib, a selective cyclo-oxygenase-2 inhibitor, enhances the response to preoperative paclitaxel and carboplatin in early-stage non-small-cell lung cancer
-
DOI 10.1200/JCO.2003.07.127
-
Altorki NK, Keresztes RS, Port JL, et al. Celecoxib, a selective cyclo-oxygenase-2 inhibitor, enhances the response to preoperative paclitaxel and carboplatin in early-stage non-small-cell lung cancer. J Clin Oncol 2003;21:2645-2650 (Pubitemid 46606306)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.14
, pp. 2645-2650
-
-
Altorki, N.K.1
Keresztes, R.S.2
Port, J.L.3
Libby, D.M.4
Korst, R.J.5
Flieder, D.B.6
Ferrara, C.A.7
Yankelevitz, D.F.8
Subbaramaiah, K.9
Pasmantier, M.W.10
Dannenberg, A.J.11
-
42
-
-
0027323229
-
Pathologic complete response in advanced non-small-cell lung cancer following preoperative chemotherapy: Implications for the design of future non-small-cell lung cancer combined modality trials
-
Pisters KM, Kris MG, Gralla RJ, et al. Pathologic complete response in advanced non-small-cell lung cancer following preoperative chemotherapy: implications for the design of future non-small-cell lung cancer combined modality trials. J Clin Oncol 1993;11:1757-1762 (Pubitemid 23277329)
-
(1993)
Journal of Clinical Oncology
, vol.11
, Issue.9
, pp. 1757-1762
-
-
Pisters, K.M.W.1
Kris, M.G.2
Gralla, R.J.3
Zaman, M.B.4
Heelan, R.T.5
Martini, N.6
-
43
-
-
0034685876
-
Microtubule-interfering agents stimulate the transcription of cyclooxygenase-2. Evidence for involvement of ERK1/2 and p38 mitogen- Activated protein kinase pathways
-
DOI 10.1074/jbc.275.20.14838
-
Subbaramaiah K, Hart JC, Norton L, et al. Microtubule-interfering agents stimulate the transcription of cyclooxygenase-2. Evidence for involvement of ERK1/2 and p38 mitogen- activated protein kinase pathways. J Biol Chem 2000;275:14838-14845 (Pubitemid 30337196)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.20
, pp. 14838-14845
-
-
Subbaramaiah, K.1
Hart, J.C.2
Norton, L.3
Dannenberg, A.J.4
-
44
-
-
20344380457
-
Chemotherapy induces the expression of cyclooxygenase-2 in non-small cell lung cancer
-
DOI 10.1158/1078-0432.CCR-05-0108
-
Altorki NK, Port JL, Zhang F, et al. Chemotherapy induces the expression of cyclooxygenase-2 in non-small cell lung cancer. Clin Cancer Res 2005;11:4191-4197 (Pubitemid 40791585)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.11
, pp. 4191-4197
-
-
Altorki, N.K.1
Port, J.L.2
Zhang, F.3
Golijanin, D.4
Thaler, H.T.5
Duffield-Lillico, A.J.6
Subbaramaiah, K.7
Dannenberg, A.J.8
-
45
-
-
67649632725
-
Celecoxib combined with fixed dose-rate Gemcitabine (FDR-Gem)/CDDP as induction chemotherapy for stage III non-small cell lung cancer (NSCLC)
-
Milella M, Ceribelli A, Gelibter A, et al. Celecoxib combined with fixed dose-rate Gemcitabine (FDR-Gem)/CDDP as induction chemotherapy for stage III non-small cell lung cancer (NSCLC). J Clin Oncol 2005;23:7324
-
(2005)
J Clin Oncol
, vol.23
, pp. 7324
-
-
Milella, M.1
Ceribelli, A.2
Gelibter, A.3
-
46
-
-
0034095853
-
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens
-
Fossella FV, Devore R, Kerr RN, et al. Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group. J Clin Oncol 2000;18:2354-2362 (Pubitemid 30415821)
-
(2000)
Journal of Clinical Oncology
, vol.18
, Issue.12
, pp. 2354-2362
-
-
Fossella, F.V.1
Devore, R.2
Kerr, R.N.3
Crawford, J.4
Natale, R.R.5
Dunphy, F.6
Kalman, L.7
Miller, V.8
Lee, J.S.9
Moore, M.10
Gandara, D.11
Karp, D.12
Vokes, E.13
Kris, M.14
Kim, Y.15
Gamza, F.16
Hammershaimb, L.17
-
47
-
-
25144442153
-
Targeting cyclooxygenase-2 in recurrent non-small cell lung cancer: A phase II trial of celecoxib and docetaxel
-
DOI 10.1158/1078-0432.CCR-05-0436
-
Csiki I, Morrow JD, Sandler A, et al. Targeting cyclooxygenase-2 in recurrent non-small cell lung cancer: a phase II trial of celecoxib and docetaxel. Clin Cancer Res 2005;11:6634-6640 (Pubitemid 41339004)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.18
, pp. 6634-6640
-
-
Csiki, I.1
Morrow, J.D.2
Sandler, A.3
Shyr, Y.4
Oates, J.5
Williams, M.K.6
Dang, T.7
Carbone, D.P.8
Johnson, D.H.9
-
48
-
-
0014944305
-
Inactivation of prostaglandins by the lungs
-
Piper PJ, Vane JR, Wyllie JH. Inactivation of prostaglandins by the lungs. Nature 1970;225:600-604
-
(1970)
Nature
, vol.225
, pp. 600-604
-
-
Piper, P.J.1
Vane, J.R.2
Wyllie, J.H.3
-
49
-
-
0016918043
-
Quantifications of the major urinary metabolite of the e prostaglandins by mass spectrometry: Evaluation of the method's application to clinical studies
-
Seyberth HW, Sweetman BJ, Frolich JC, et al. Quantifications of the major urinary metabolite of the E prostaglandins by mass spectrometry: evaluation of the method's application to clinical studies. Prostaglandins 1976;11:381-397
-
(1976)
Prostaglandins
, vol.11
, pp. 381-397
-
-
Seyberth, H.W.1
Sweetman, B.J.2
Frolich, J.C.3
-
50
-
-
5644272862
-
Quantification of the major urinary metabolite of PGE(2) by a liquid chromatographic/mass spectrometric assay: Determination of cyclooxygenase- specific PGE(2) synthesis in healthy humans and those with lung cancer
-
Murphey LJ, Williams MK, Sanchez SC, et al. Quantification of the major urinary metabolite of PGE(2) by a liquid chromatographic/mass spectrometric assay: determination of cyclooxygenase-specific PGE(2) synthesis in healthy humans and those with lung cancer. Anal Biochem 2004;334:266-275
-
(2004)
Anal Biochem
, vol.334
, pp. 266-275
-
-
Murphey, L.J.1
Williams, M.K.2
Sanchez, S.C.3
-
51
-
-
23844555182
-
2, are increased in smokers
-
DOI 10.1158/1078-0432.CCR-05-0733
-
Gross ND, Boyle JO, Morrow JD, et al. Levels of prostaglandin E metabolite, the major urinary metabolite of prostaglandin E2, are increased in smokers. Clin Cancer Res 2005;11:6087-6093 (Pubitemid 41170341)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.16
, pp. 6087-6093
-
-
Gross, N.D.1
Boyle, J.O.2
Morrow, J.D.3
Williams, M.K.4
Moskowitz, C.S.5
Subbaramaiah, K.6
Dannenberg, A.J.7
Duffield-Lillico, A.J.8
-
52
-
-
17044384979
-
Docetaxel and cyclooxygenase-2 inhibition with celecoxib for advanced non-small cell lung cancer progressing after platinum-based chemotherapy: A multicenter phase II trial
-
DOI 10.1016/j.lungcan.2004.11.004
-
Nugent FW, Mertens WC, Graziano S, et al. Docetaxel and cyclooxygenase-2 inhibition with celecoxib for advanced non-small cell lung cancer progressing after platinum-based chemotherapy: a multicenter phase II trial. Lung Cancer 2005;48:267-273 (Pubitemid 40501817)
-
(2005)
Lung Cancer
, vol.48
, Issue.2
, pp. 267-273
-
-
Nugent, F.W.1
Mertens, W.C.2
Graziano, S.3
Levitan, N.4
Collea, R.5
Gajra, A.6
Marshall, J.7
McCann, J.8
-
53
-
-
61449530281
-
Phase II study of celecoxib and docetaxel in non-small cell lung cancer (NSCLC) patients with progression after platinum-based therapy
-
Schneider BJ, Kalemkerian GP, Kraut MJ, et al. Phase II study of celecoxib and docetaxel in non-small cell lung cancer (NSCLC) patients with progression after platinum-based therapy. J Thorac Oncol 2008;3:1454-1459
-
(2008)
J Thorac Oncol
, vol.3
, pp. 1454-1459
-
-
Schneider, B.J.1
Kalemkerian, G.P.2
Kraut, M.J.3
-
54
-
-
0032884835
-
Cyclooxygenase-2 is essential for normal recovery from 5-fluorouracil- Induced myelotoxicity in mice
-
DOI 10.1016/S0301-472X(99)00087-9, PII S0301472X99000879
-
Lorenz M, Slaughter HS, Wescott DM, et al. Cyclooxygenase-2 is essential for normal recovery from 5-fluorouracil-induced myelotoxicity in mice. Exp Hematol 1999;27:1494-1502 (Pubitemid 29458423)
-
(1999)
Experimental Hematology
, vol.27
, Issue.10
, pp. 1494-1502
-
-
Lorenz, M.1
Slaughter, H.S.2
Wescott, D.M.3
Carter, S.I.4
Schnyder, B.5
Dinchuk, J.E.6
Car, B.D.7
-
55
-
-
33749581510
-
The combination of the selective cyclooxygenase-2 inhibitor celecoxib with weekly paclitaxel is a safe and active second-line therapy for non-small cell lung cancer: A phase II study with biological correlates
-
Gasparini G, Meo S, Comella G, et al. The combination of the selective cyclooxygenase-2 inhibitor celecoxib with weekly paclitaxel is a safe and active second-line therapy for non-small cell lung cancer: a phase II study with biological correlates. Cancer J 2005;11:209-216 (Pubitemid 44698809)
-
(2005)
Cancer Journal
, vol.11
, Issue.3
, pp. 209-216
-
-
Gasparini, G.1
Meo, S.2
Comella, G.3
Stani, S.C.4
Mariani, L.5
Gamucci, T.6
Avallone, A.7
Lo Vullo, S.8
Mansueto, G.9
Bonginelli, P.10
Gattuso, D.11
Gion, M.12
-
56
-
-
10744223982
-
Prospective randomised phase II study of docetaxel versus paclitaxel administered weekly in patients with non-small-cell lung cancer previously treated with platinum-based chemotherapy
-
DOI 10.1093/annonc/mdg456
-
Esteban E, Gonzalez de Sande L, Fernandez Y, et al. Prospective randomised phase II study of docetaxel versus paclitaxel administered weekly in patients with non-small-cell lung cancer previously treated with platinum-based chemotherapy. Ann Oncol 2003;14:1640-1647 (Pubitemid 37455813)
-
(2003)
Annals of Oncology
, vol.14
, Issue.11
, pp. 1640-1647
-
-
Esteban-Gonzalez, E.1
Gonzalez De Sande, L.2
Fernandez, Y.3
Corral, N.4
Fra, J.5
Muniz, I.6
Vieitez, J.M.7
Palacio, I.8
Fernandez, J.L.9
Estrada, E.10
Lacave, A.J.11
-
57
-
-
27144497139
-
Targeting COX-2/PG-E2 with a COX-2 inhibitor in combination with chemotherapy for non-small cell lung cancer: Are we ready for phase III?
-
Aisner J. Targeting COX-2/PG-E2 with a COX-2 inhibitor in combination with chemotherapy for non-small cell lung cancer: are we ready for phase III? Cancer J 2005;11:201-203
-
(2005)
Cancer J
, vol.11
, pp. 201-203
-
-
Aisner, J.1
-
58
-
-
33750626760
-
Randomized phase II trial of docetaxel/irinotecan and gemcitabine/ irinotecan with or without celecoxib in the second-line treatment of non-small-cell lung cancer
-
DOI 10.1200/JCO.2006.07.4773
-
Lilenbaum R, Socinski MA, Altorki NK, et al. Randomized phase II trial of docetaxel/irinotecan and gemcitabine/ irinotecan with or without celecoxib in the second-line treatment of non-small-cell lung cancer. J Clin Oncol 2006;24:4825-4832 (Pubitemid 46630908)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.30
, pp. 4825-4832
-
-
Lilenbaum, R.1
Socinski, M.A.2
Altorki, N.K.3
Hart, L.L.4
Keresztes, R.S.5
Hariharan, S.6
Morrison, M.E.7
Fayyad, R.8
Bonomi, P.9
-
59
-
-
34249942270
-
Failure of apoptosis and activation on NFkappaB by celecoxib and aspirin in lung cancer cell lines
-
Gradilone A, Silvestri I, Scarpa S, et al. Failure of apoptosis and activation on NFkappaB by celecoxib and aspirin in lung cancer cell lines. Oncol Rep 2007;17:823-828
-
(2007)
Oncol Rep
, vol.17
, pp. 823-828
-
-
Gradilone, A.1
Silvestri, I.2
Scarpa, S.3
-
60
-
-
34948813028
-
Celecoxib induces MRP-4 in lung cancer cells: Therapeutic implications [4]
-
DOI 10.1200/JCO.2007.12.2945
-
Gradilone A, Pulcinelli FM, Lotti LV, et al. Celecoxib induces MRP-4 in lung cancer cells: therapeutic implications. J Clin Oncol 2007;25:4318-4320 (Pubitemid 47548578)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.27
, pp. 4318-4320
-
-
Gradilone, A.1
Pulcinelli, F.M.2
Lotti, L.V.3
Martino, S.4
Mattiello, T.5
Frati, L.6
Agliano, A.M.7
Gazzaniga, P.8
-
61
-
-
27144541444
-
Human multidrug resistance associated protein 4 confers resistance to camptothecins
-
DOI 10.1007/s11095-005-7595-z
-
Tian Q, Zhang J, Tan TM, et al. Human multidrug resistance associated protein 4 confers resistance to camptothecins. Pharm Res 2005;22:1837-1853 (Pubitemid 41504337)
-
(2005)
Pharmaceutical Research
, vol.22
, Issue.11
, pp. 1837-1853
-
-
Tian, Q.1
Zhang, J.2
Tan, T.M.C.3
Chan, E.4
Duan, W.5
Sui, Y.C.6
Boelsterli, U.A.7
Ho, P.C.-L.8
Yang, H.9
Bian, J.-S.10
Huang, M.11
Zhu, Y.-Z.12
Xiong, W.13
Li, X.14
Zhou, S.15
-
62
-
-
33646560295
-
Phase I and pharmacokinetic study of docetaxel, irinotecan, and celecoxib in patients with advanced non-small cell lung cancer
-
DOI 10.1007/s10637-005-3259-4
-
Argiris A, Kut V, Luong L, et al. Phase I and pharmacokinetic study of docetaxel, irinotecan, and celecoxib in patients with advanced non-small cell lung cancer. Invest New Drugs 2006;24:203-212 (Pubitemid 43723897)
-
(2006)
Investigational New Drugs
, vol.24
, Issue.3
, pp. 203-212
-
-
Argiris, A.1
Kut, V.2
Luong, L.3
Avram, M.J.4
-
63
-
-
0036595629
-
Epithelial-mesenchymal transitions in tumour progression
-
Thiery JP. Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer 2002;2:442-454
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 442-454
-
-
Thiery, J.P.1
-
64
-
-
44449144396
-
Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis
-
DOI 10.1016/j.devcel.2008.05.009, PII S1534580708002098
-
Yang J, Weinberg RA. Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. Dev Cell 2008;14:818-829 (Pubitemid 351757205)
-
(2008)
Developmental Cell
, vol.14
, Issue.6
, pp. 818-829
-
-
Yang, J.1
Weinberg, R.A.2
-
65
-
-
40049084003
-
Inflammation, epithelial to mesenchymal transition, and epidermal growth factor receptor tyrosine kinase inhibitor resistance
-
DOI 10.1097/JTO.0b013e3181630ece, PII 0124389420080200000003
-
Krysan K, Lee JM, Dohadwala M, et al. Inflammation, epithelial to mesenchymal transition, and epidermal growth factor receptor tyrosine kinase inhibitor resistance. J Thorac Oncol 2008;3:107-110 (Pubitemid 351323182)
-
(2008)
Journal of Thoracic Oncology
, vol.3
, Issue.2
, pp. 107-110
-
-
Krysan, K.1
Lee, J.M.2
Dohadwala, M.3
Gardner, B.K.4
Reckamp, K.L.5
Garon, E.6
John, M.S.7
Sharma, S.8
Dubinett, S.M.9
-
66
-
-
27144477683
-
Epithelial to mesenchymal transition is a determinant of sensitivity of non-small-cell lung carcinoma cell lines and xenografts to epidermal growth factor receptor inhibition
-
DOI 10.1158/0008-5472.CAN-05-1058
-
Thomson S, Buck E, Petti F, et al. Epithelial to mesenchymal transition is a determinant of sensitivity of non-small-cell lung carcinoma cell lines and xenografts to epidermal growth factor receptor inhibition. Cancer Res 2005;65:9455-9462 (Pubitemid 41508014)
-
(2005)
Cancer Research
, vol.65
, Issue.20
, pp. 9455-9462
-
-
Thomson, S.1
Buck, E.2
Petti, F.3
Griffin, G.4
Brown, E.5
Ramnarine, N.6
Iwata, K.K.7
Gibson, N.8
Haley, J.D.9
-
67
-
-
31544452076
-
Restoring E-cadherin expression increases sensitivity to epidermal growth factor receptor inhibitors in lung cancer cell lines
-
DOI 10.1158/0008-5472.CAN-05-1988
-
Witta SE, Gemmill RM, Hirsch FR, et al. Restoring E-cadherin expression increases sensitivity to epidermal growth factor receptor inhibitors in lung cancer cell lines. Cancer Res 2006;66:944-950 (Pubitemid 43165962)
-
(2006)
Cancer Research
, vol.66
, Issue.2
, pp. 944-950
-
-
Witta, S.E.1
Gemmill, R.M.2
Hirsch, F.R.3
Coldren, C.D.4
Hedman, K.5
Ravdel, L.6
Helfrich, B.7
Dziadziuszko, R.8
Chan, D.C.9
Sugita, M.10
Chan, Z.11
Baron, A.12
Franklin, W.13
Drabkin, H.A.14
Girard, L.15
Gazdar, A.F.16
Minna, J.D.17
Bunn Jr., P.A.18
-
68
-
-
0035877634
-
Non-small Cell Lung Cancer Cyclooxygenase-2-dependent Invasion is Mediated by CD44
-
DOI 10.1074/jbc.C100140200
-
Dohadwala M, Luo J, Zhu L, et al. Non-small cell lung cancer cyclooxygenase-2-dependent invasion is mediated by CD44. J Biol Chem 2001;276:20809-20812 (Pubitemid 37413056)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.24
, pp. 20809-20812
-
-
Dohadwala, M.1
Luo, J.2
Zhu, L.3
Lin, Y.4
Dougherty, G.J.5
Sharma, S.6
Huang, M.7
Pold, M.8
Batra, R.K.9
Dubinett, S.M.10
-
69
-
-
0346736504
-
Autocrine/paracrine prostaglandin E2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasion
-
DOI 10.1074/jbc.M210707200
-
Dohadwala M, Batra RK, Luo J, et al. Autocrine/paracrine prostaglandin E2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasion. J Biol Chem 2002;277:50828-50833 (Pubitemid 36042248)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.52
, pp. 50828-50833
-
-
Dohadwala, M.1
Batra, R.K.2
Luo, J.3
Lin, Y.4
Krysan, K.5
Pold, M.6
Sharma, S.7
Dubinett, S.M.8
-
70
-
-
33744925683
-
Cyclooxygenase-2-dependent regulation of E-cadherin: Prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer
-
Dohadwala M, Yang SC, Luo J, et al. Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer. Cancer Res 2006;66:5338-5345
-
(2006)
Cancer Res
, vol.66
, pp. 5338-5345
-
-
Dohadwala, M.1
Yang, S.C.2
Luo, J.3
-
71
-
-
33745219813
-
A phase I trial to determine the optimal biological dose of celecoxib when combined with erlotinib in advanced non-small cell lung cancer
-
DOI 10.1158/1078-0432.CCR-06-0112
-
Reckamp KL, Krysan K, Morrow JD, et al. A phase I trial to determine the optimal biological dose of celecoxib when combined with erlotinib in advanced non-small cell lung cancer. Clin Cancer Res 2006;12:3381-3388 (Pubitemid 43910883)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.11 I
, pp. 3381-3388
-
-
Reckamp, K.L.1
Krysan, K.2
Morrow, J.D.3
Milne, G.L.4
Newman, R.A.5
Tucker, C.6
Elashoff, R.M.7
Dubinett, S.M.8
Figlin, R.A.9
-
72
-
-
42249111036
-
The potential predictive value of cyclooxygenase-2 expression and increased risk of gastrointestinal hemorrhage in advanced non-small cell lung cancer patients treated with erlotinib and celecoxib
-
DOI 10.1158/1078-0432.CCR-07-4013
-
Fidler MJ, Argiris A, Patel JD, et al. The potential predictive value of cyclooxygenase-2 expression and increased risk of gastrointestinal hemorrhage in advanced non-small cell lung cancer patients treated with erlotinib and celecoxib. Clin Cancer Res 2008;14:2088-2094 (Pubitemid 351551120)
-
(2008)
Clinical Cancer Research
, vol.14
, Issue.7
, pp. 2088-2094
-
-
Fidler, M.J.1
Argiris, A.2
Patel, J.D.3
Johnson, D.H.4
Sandler, A.5
Villaflor, V.M.6
Coon IV, J.7
Buckingham, L.8
Kaiser, K.9
Basu, S.10
Bonomi, P.11
-
73
-
-
23044454675
-
Significant effect of capecitabine on the pharmacokinetics and pharmacodynamics of warfarin in patients with cancer
-
DOI 10.1200/JCO.2005.09.129
-
Camidge R, Reigner B, Cassidy J, et al. Significant effect of capecitabine on the pharmacokinetics and pharmacodynamics of warfarin in patients with cancer. J Clin Oncol 2005;23:4719-4725 (Pubitemid 46224075)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.21
, pp. 4719-4725
-
-
Camidge, R.1
Reigner, B.2
Cassidy, J.3
Grange, S.4
Abt, M.5
Weidekamm, E.6
Jodrell, D.7
-
74
-
-
22044445517
-
Erlotinib in previously treated non-small-cell lung cancer
-
DOI 10.1056/NEJMoa050753
-
Shepherd FA, Rodrigues Pereira J, Ciuleanu T, et al. Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med 2005;353:123-132 (Pubitemid 41058344)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.2
, pp. 123-132
-
-
Shepherd, F.A.1
Pereira, J.R.2
Ciuleanu, T.3
Eng, H.T.4
Hirsh, V.5
Thongprasert, S.6
Campos, D.7
Maoleekoonpiroj, S.8
Smylie, M.9
Martins, R.10
Van Kooten, M.11
Dediu, M.12
Findlay, B.13
Tu, D.14
Johnston, D.15
Bezjak, A.16
Clark, G.17
Santabarbara, P.18
Seymour, L.19
-
75
-
-
34247882824
-
Phase II study of gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), and celecoxib, a cyclooxygenase-2 (COX-2) inhibitor, in patients with platinum refractory non-small cell lung cancer (NSCLC)
-
DOI 10.1097/01.JTO.0000263712.61697.69, PII 0124389420070400000009
-
Gadgeel SM, Ruckdeschel JC, Heath EI, et al. Phase II study of gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), and celecoxib, a cyclooxygenase-2 (COX-2) inhibitor, in patients with platinum refractory non-small cell lung cancer (NSCLC). J Thorac Oncol 2007;2:299-305 (Pubitemid 47181712)
-
(2007)
Journal of Thoracic Oncology
, vol.2
, Issue.4
, pp. 299-305
-
-
Gadgeel, S.M.1
Ruckdeschel, J.C.2
Heath, E.I.3
Heilbrun, L.K.4
Venkatramanamoorthy, R.5
Wozniak, A.6
-
76
-
-
27544503230
-
Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: Results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer)
-
DOI 10.1016/S0140-6736(05)67625-8, PII S0140673605676258
-
Thatcher N, Chang A, Parikh P, et al. Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer). Lancet 2005;366:1527-1537 (Pubitemid 41540110)
-
(2005)
Lancet
, vol.366
, Issue.9496
, pp. 1527-1537
-
-
Thatcher, N.1
Chang, A.2
Parikh, P.3
Pereira, J.R.4
Ciuleanu, T.5
Von Pawel, J.6
Thongprasert, S.7
Tan, E.H.8
Pemberton, K.9
Archer, V.10
Carroll, K.11
-
77
-
-
41749124798
-
Gefitinib plus celecoxib in chemotherapy-naive patients with stage IIIB/IV non-small cell lung cancer: A phase II study from the Hoosier Oncology Group
-
Agarwala A, Fisher W, Bruetman D, et al. Gefitinib plus celecoxib in chemotherapy-naive patients with stage IIIB/IV non-small cell lung cancer: a phase II study from the Hoosier Oncology Group. J Thorac Oncol 2008;3:374-379
-
(2008)
J Thorac Oncol
, vol.3
, pp. 374-379
-
-
Agarwala, A.1
Fisher, W.2
Bruetman, D.3
-
78
-
-
34548212389
-
Combination therapy with gefitinib and rofecoxib in patients with platinum-pretreated relapsed non-small-cell lung cancer
-
DOI 10.1200/JCO.2006.09.2791
-
O'Byrne KJ, Danson S, Dunlop D, et al. Combination therapy with gefitinib and rofecoxib in patients with platinum-pretreated relapsed non small-cell lung cancer. J Clin Oncol 2007;25:3266-3273 (Pubitemid 47325611)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.22
, pp. 3266-3273
-
-
O'Byrne, K.J.1
Danson, S.2
Dunlop, D.3
Botwood, N.4
Taguchi, F.5
Carbone, D.6
Ranson, M.7
-
79
-
-
39749191925
-
Epidermal growth factor receptor immunohistochemistry: Comparison of antibodies and cutoff points to predict benefit from gefitinib in a phase 3 placebo-controlled study in advanced nonsmall-cell lung cancer
-
DOI 10.1002/cncr.23282
-
Hirsch FR, Dziadziuszko R, Thatcher N, et al. Epidermal growth factor receptor immunohistochemistry: comparison of antibodies and cutoff points to predict benefit from gefitinib in a phase 3 placebo-controlled study in advanced nonsmall-cell lung cancer. Cancer 2008;112:1114-1121 (Pubitemid 351304597)
-
(2008)
Cancer
, vol.112
, Issue.5
, pp. 1114-1121
-
-
Hirsch, F.R.1
Dziadziuszko, R.2
Thatcher, N.3
Mann, H.4
Watkins, C.5
Parums, D.V.6
Speake, G.7
Holloway, B.8
Bunn Jr., P.A.9
Franklin, W.A.10
-
80
-
-
34748817976
-
Membrane prostaglandin e synthase-1: A novel therapeutic target
-
DOI 10.1124/pr.59.3.1
-
Samuelsson B, Morgenstern R, Jakobsson P-J. Membrane prostaglandin E synthase-1: A novel therapeutic target. Pharmacol Rev 2007;59:207-224 (Pubitemid 47481434)
-
(2007)
Pharmacological Reviews
, vol.59
, Issue.3
, pp. 207-224
-
-
Samuelsson, B.1
Morgenstern, R.2
Jakobsson, P.-J.3
-
81
-
-
0034813862
-
Inducible prostaglandin e synthase is overexpressed in non-small cell lung cancer
-
Yoshimatsu K, Altorki NK, Golijanin D, et al. Inducible prostaglandin E synthase is overexpressed in non-small cell lung cancer. Clin Cancer Res 2001;7:2669-2674 (Pubitemid 32911370)
-
(2001)
Clinical Cancer Research
, vol.7
, Issue.9
, pp. 2669-2674
-
-
Yoshimatsu, K.1
Altorki, N.K.2
Golijanin, D.3
Zhang, F.4
Jakobsson, P.-J.5
Dannenberg, A.J.6
Subbaramaiah, K.7
-
82
-
-
56649103898
-
Expression and purification of human mPGES-1 in E. coli and identification of inhibitory compounds from a drug-library
-
Kim WI, Choi KA, Do HS, et al. Expression and purification of human mPGES-1 in E. coli and identification of inhibitory compounds from a drug-library. BMB Rep 2008;41:808-813
-
(2008)
BMB Rep
, vol.41
, pp. 808-813
-
-
Kim, W.I.1
Choi, K.A.2
Do, H.S.3
-
83
-
-
39449137882
-
Human microsomal prostaglandin e synthase-1 (mPGES-1) binding with inhibitors and the quantitative structure-activity correlation
-
DOI 10.1021/ci700315c
-
Abdulhameed MDM, Hamza A, Liu J, et al. Human microsomal prostaglandin E synthase-1 (mPGES-1) binding with inhibitors and the quantitative structure-activity correlation. J Chem Inf Model 2008;48:179-185 (Pubitemid 351271063)
-
(2008)
Journal of Chemical Information and Modeling
, vol.48
, Issue.1
, pp. 179-185
-
-
Abdul Hameed, M.D.M.1
Hamza, A.2
Liu, J.3
Huang, X.4
Zhan, C.-G.5
-
84
-
-
34250815766
-
Inhibition of epidermal growth factor receptor signaling elevates 15-hydroxyprostaglandin dehydrogenase in non-small-cell lung cancer
-
DOI 10.1158/0008-5472.CAN-06-2287
-
Yang L, Amann JM, Kikuchi T, et al. Inhibition of epidermal growth factor receptor signaling elevates 15-hydroxyprostaglandin dehydrogenase in non-small-cell lung cancer. Cancer Res 2007;67:5587-5593 (Pubitemid 46984987)
-
(2007)
Cancer Research
, vol.67
, Issue.12
, pp. 5587-5593
-
-
Yang, L.1
Amann, J.M.2
Kikuchi, T.3
Porta, R.4
Guix, M.5
Gonzalez, A.6
Park, K.-H.7
Billheimer, D.8
Arteaga, C.L.9
Tai, H.-H.10
Dubois, R.11
Carbone, D.P.12
Johnson, D.H.13
-
85
-
-
48549087414
-
15-Hydroxyprostaglandin dehydrogenase is a target of hepatocyte nuclear factor 3beta and a tumor suppressor in lung cancer
-
Huang G, Eisenberg R, Yan M, et al. 15-Hydroxyprostaglandin dehydrogenase is a target of hepatocyte nuclear factor 3beta and a tumor suppressor in lung cancer. Cancer Res 2008;68:5040-5048
-
(2008)
Cancer Res
, vol.68
, pp. 5040-5048
-
-
Huang, G.1
Eisenberg, R.2
Yan, M.3
-
86
-
-
57249089707
-
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase regulates levels of bioactive lipids in non-small cell lung cancer
-
Hughes D, Otani T, Yang P, et al. NAD+-dependent 15-hydroxyprostaglandin dehydrogenase regulates levels of bioactive lipids in non-small cell lung cancer. Cancer Prev Res 2008;1:241-249
-
(2008)
Cancer Prev Res
, vol.1
, pp. 241-249
-
-
Hughes, D.1
Otani, T.2
Yang, P.3
-
87
-
-
13544268334
-
15-hydroxyprostaglandin dehydrogenase is down-regulated in colorectal cancer
-
DOI 10.1074/jbc.M411221200
-
Backlund MG, Mann JR, Holla VR, et al. 15-Hydroxyprostaglandin dehydrogenase is down-regulated in colorectal cancer. J Biol Chem 2005;280:3217-3223 (Pubitemid 40223783)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.5
, pp. 3217-3223
-
-
Backlund, M.G.1
Mann, J.R.2
Holla, V.R.3
Buchanan, F.G.4
Tai, H.-H.5
Musiek, E.S.6
Milne, G.L.7
Katkuri, S.8
Dubois, R.N.9
-
88
-
-
13444269594
-
+-linked 15-hydroxyprostaglandin dehydrogenase (15-PGDH) behaves as a tumor suppressor in lung cancer
-
DOI 10.1093/carcin/bgh277
-
Ding Y, Tong M, Liu S, et al. NAD+-linked 15-hydroxyprostaglandin dehydrogenase (15-PGDH) behaves as a tumor suppressor in lung cancer. Carcinogenesis 2005;26:65-72 (Pubitemid 40207700)
-
(2005)
Carcinogenesis
, vol.26
, Issue.1
, pp. 65-72
-
-
Ding, Y.1
Tong, M.2
Liu, S.3
Moscow, J.A.4
Tai, H.-H.5
-
89
-
-
44349148410
-
Mutations in 15-hydroxyprostaglandin dehydrogenase cause primary hypertrophic osteoarthropathy
-
DOI 10.1038/ng.153, PII NG153
-
Uppal S, Diggle CP, Carr IM, et al. Mutations in 15-hydroxyprostaglandin dehydrogenase cause primary hypertrophic osteoarthropathy. Nat Genet 2008;40:789-793 (Pubitemid 351748871)
-
(2008)
Nature Genetics
, vol.40
, Issue.6
, pp. 789-793
-
-
Uppal, S.1
Diggle, C.P.2
Carr, I.M.3
Fishwick, C.W.G.4
Ahmed, M.5
Ibrahim, G.H.6
Helliwell, P.S.7
Latos-Bielenska, A.8
Phillips, S.E.V.9
Markham, A.F.10
Bennett, C.P.11
Bonthron, D.T.12
-
90
-
-
44349168815
-
2
-
DOI 10.1038/ng0608-691, PII NG0608691
-
Coggins KG, Coffman TM, Koller BH. The Hippocratic finger points the blame at PGE2. Nat Genet 2008;40:691-692 (Pubitemid 351748881)
-
(2008)
Nature Genetics
, vol.40
, Issue.6
, pp. 691-692
-
-
Coggins, K.G.1
Coffman, T.M.2
Koller, B.H.3
-
91
-
-
34347353320
-
2 in non-small-cell lung cancer cells by up-regulating 15-hydroxyprostaglandin dehydrogenase
-
DOI 10.1124/mol.106.033357
-
Hazra S, Batra RK, Tai HH, et al. Pioglitazone and rosiglitazone decrease prostaglandin E2 in non-small-cell lung cancer cells by up-regulating 15-hydroxyprostaglandin dehydrogenase. Mol Pharmacol 2007;71:1715-1720 (Pubitemid 47010924)
-
(2007)
Molecular Pharmacology
, vol.71
, Issue.6
, pp. 1715-1720
-
-
Hazra, S.1
Batra, R.K.2
Tai, H.H.3
Sharma, S.4
Cui, X.5
Dubinett, S.M.6
-
92
-
-
61549141756
-
Focusing downstream in lung cancer prevention: 15-hydroxyprostaglandin dehydrogenase
-
Dubinett SM, Mao JT, Hazra S. Focusing downstream in lung cancer prevention: 15-hydroxyprostaglandin dehydrogenase. Cancer Prev Res 2008;1:223-225
-
(2008)
Cancer Prev Res
, vol.1
, pp. 223-225
-
-
Dubinett, S.M.1
Mao, J.T.2
Hazra, S.3
-
93
-
-
34248192254
-
Thiazolidinediones and the risk of lung, prostate, and colon cancer in patients with diabetes
-
DOI 10.1200/JCO.2006.07.2777
-
Govindarajan R, Ratnasinghe L, Simmons DL, et al. Thiazolidinediones and the risk of lung, prostate, and colon cancer in patients with diabetes. J Clin Oncol 2007;25:1476-1481 (Pubitemid 46733074)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.12
, pp. 1476-1481
-
-
Govindarajan, R.1
Ratnasinghe, L.2
Simmons, D.L.3
Siegel, E.R.4
Midathada, M.V.5
Kim, L.6
Kim, P.J.7
Owens, R.J.8
Lang, N.P.9
-
94
-
-
34247558604
-
Synergy between PPARgamma Ligands and Platinum-Based Drugs in Cancer
-
DOI 10.1016/j.ccr.2007.02.025, PII S1535610807000669
-
Girnun GD, Naseri E, Vafai SB, et al. Synergy between PPAR[gamma] ligands and platinum-based drugs in cancer. Cancer Cell 2007;11:395-406 (Pubitemid 46670076)
-
(2007)
Cancer Cell
, vol.11
, Issue.5
, pp. 395-406
-
-
Girnun, G.D.1
Naseri, E.2
Vafai, S.B.3
Qu, L.4
Szwaya, J.D.5
Bronson, R.6
Alberta, J.A.7
Spiegelman, B.M.8
-
95
-
-
34247160020
-
2 via the phosphatidylinositol 3-kinase and Akt pathway
-
DOI 10.1074/jbc.M610153200
-
Kapoor M, Kojima F, Qian M, et al. Microsomal prostaglandin E synthase-1 deficiency is associated with elevated peroxisome proliferator-activated receptor gamma: regulation by prostaglandin E2 the phosphatidylinositol 3-kinase and Akt pathway. J Biol Chem 2007;282:5356-5366 (Pubitemid 47093760)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.8
, pp. 5356-5366
-
-
Kapoor, M.1
Kojima, F.2
Qian, M.3
Yang, L.4
Crofford, L.J.5
-
96
-
-
58149178162
-
Regression of drug-resistant lung cancer the combination of rosiglitazone and carboplatin
-
Girnun GD, Chen L, Silvaggi J, et al. Regression of drug-resistant lung cancer the combination of rosiglitazone and carboplatin. Clin Cancer Res 2008;14:6478-6486
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6478-6486
-
-
Girnun, G.D.1
Chen, L.2
Silvaggi, J.3
-
97
-
-
1942502821
-
Prostanoids and prostanoid receptors in signal transduction
-
DOI 10.1016/j.biocel.2003.08.006, PII S1357272503002966
-
Bos CL, Richel DJ, Ritsema T, et al. Prostanoids and prostanoid receptors in signal transduction. Int J Biochem Cell Biol 2004;36:1187-1205 (Pubitemid 38515660)
-
(2004)
International Journal of Biochemistry and Cell Biology
, vol.36
, Issue.7
, pp. 1187-1205
-
-
Bos, C.L.1
Richel, D.J.2
Ritsema, T.3
Peppelenbosch, M.P.4
Versteeg, H.H.5
-
98
-
-
33645527575
-
Prostaglandin e receptor EP4 antagonism inhibits breast cancer metastasis
-
Ma X, Kundu N, Rifat S, et al. Prostaglandin E receptor EP4 antagonism inhibits breast cancer metastasis. Cancer Res 2006;66:2923-2927
-
(2006)
Cancer Res
, vol.66
, pp. 2923-2927
-
-
Ma, X.1
Kundu, N.2
Rifat, S.3
-
99
-
-
33750308463
-
Host and direct antitumor effects and profound reduction in tumor metastasis with selective EP4 receptor antagonism
-
DOI 10.1158/0008-5472.CAN-06-1271
-
Yang L, Huang Y, Porta R, et al. Host and direct antitumor effects and profound reduction in tumor metastasis with selective EP4 receptor antagonism. Cancer Res 2006;66:9665-9672 (Pubitemid 44623666)
-
(2006)
Cancer Research
, vol.66
, Issue.19
, pp. 9665-9672
-
-
Yang, L.1
Huang, Y.2
Porta, R.3
Yanagisawa, K.4
Gonzalez, A.5
Segi, E.6
Johnson, D.H.7
Narumiya, S.8
Carbone, D.P.9
-
100
-
-
39749101912
-
Novel strategies for the treatment of lung cancer: Modulation of eicosanoids
-
Backlund MG, Amann JM, Johnson DH. Novel strategies for the treatment of lung cancer: modulation of eicosanoids. J Clin Oncol 2008;26:825-827
-
(2008)
J Clin Oncol
, vol.26
, pp. 825-827
-
-
Backlund, M.G.1
Amann, J.M.2
Johnson, D.H.3
-
101
-
-
20144365496
-
Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention
-
DOI 10.1056/NEJMoa050405
-
Solomon SD, McMurray JJ, Pfeffer MA, et al. Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention. N Engl J Med 2005;352:1071-1080 (Pubitemid 40365348)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.11
, pp. 1071-1080
-
-
Solomon, S.D.1
McMurray, J.J.V.2
Pfeffer, M.A.3
Wittes, J.4
Fowler, R.5
Finn, P.6
Anderson, W.F.7
Zauber, A.8
Hawk, E.9
Bertagnolli, M.10
|