-
1
-
-
33745209743
-
Chronic obstructive pulmonary disease, inflammation and co-morbidity -A common inflammatory phenotype?
-
Sevenoaks MJ, Stockley RA. Chronic obstructive pulmonary disease, inflammation and co-morbidity -a common inflammatory phenotype? Respir Res 2006;7:70.
-
(2006)
Respir Res
, vol.7
, pp. 70
-
-
Sevenoaks, M.J.1
Stockley, R.A.2
-
2
-
-
43049142951
-
Inflammation in lung carcinogenesis: New targets for lung cancer chemoprevention and treatment
-
Lee JM, Yanagawa J, Peebles KA, et al. Inflammation in lung carcinogenesis: new targets for lung cancer chemoprevention and treatment. Crit Rev Oncol Hematol 2008;66:208-17.
-
(2008)
Crit Rev Oncol Hematol
, vol.66
, pp. 208-217
-
-
Lee, J.M.1
Yanagawa, J.2
Peebles, K.A.3
-
3
-
-
0033833320
-
Cyclooxygenase-2: Its rich diversity of roles and possible application of its selective inhibitors
-
Katori M, Majima M. Cyclooxygenase-2: its rich diversity of roles and possible application of its selective inhibitors. Inflamm Res 2000;49:367-92.
-
(2000)
Inflamm Res
, vol.49
, pp. 367-392
-
-
Katori, M.1
Majima, M.2
-
4
-
-
0242690224
-
COX-2 and beyond: Approaches to prostaglandin inhibition in human disease
-
FitzGerald GA. COX-2 and beyond: approaches to prostaglandin inhibition in human disease. Nat Rev Drug Discov 2003;2:879-90.
-
(2003)
Nat Rev Drug Discov
, vol.2
, pp. 879-890
-
-
Fitzgerald, G.A.1
-
5
-
-
0034665857
-
The productive conformation of arachidonic acid bound to prostaglandin synthase
-
Malkowski MG, Ginell SL, Smith WL, et al. The productive conformation of arachidonic acid bound to prostaglandin synthase. Science 2000;289: 1933-7.
-
(2000)
Science
, vol.289
, pp. 1933-1937
-
-
Malkowski, M.G.1
Ginell, S.L.2
Smith, W.L.3
-
6
-
-
0032521401
-
Non-small cell lung cancer cyclooxygenase-2-dependent regulation of cytokine balance in lymphocytes and macrophages: Up-regulation of interleukin 10 and down-regulation of interleukin 12 production
-
Huang M, Stolina M, Sharma S, et al. Non-small cell lung cancer cyclooxygenase-2-dependent regulation of cytokine balance in lymphocytes and macrophages: up-regulation of interleukin 10 and down-regulation of interleukin 12 production. Cancer Res 1998;58:1208-16.
-
(1998)
Cancer Res
, vol.58
, pp. 1208-1216
-
-
Huang, M.1
Stolina, M.2
Sharma, S.3
-
7
-
-
0033574630
-
Inhibition of cyclooxygenase-2 gene expression by p53
-
Subbaramaiah K, Altorki N, Chung WJ, et al. Inhibition of cyclooxygenase-2 gene expression by p53. J Biol Chem 1999;274:10911-5.
-
(1999)
J Biol Chem
, vol.274
, pp. 10911-10915
-
-
Subbaramaiah, K.1
Altorki, N.2
Chung, W.J.3
-
8
-
-
31544467810
-
Thioredoxin- 1 modulates transcription of cyclooxygenase-2 via hypoxia-inducible factor-1α in non-small cell lung cancer
-
Csiki I, Yanagisawa K, Haruki N, et al. Thioredoxin- 1 modulates transcription of cyclooxygenase-2 via hypoxia-inducible factor-1α in non-small cell lung cancer. Cancer Res 2006;66:143-50.
-
(2006)
Cancer Res
, vol.66
, pp. 143-150
-
-
Csiki, I.1
Yanagisawa, K.2
Haruki, N.3
-
9
-
-
23844461887
-
Chemoprevention strategies with cyclooxygenase-2 inhibitors for lung cancer
-
Mao JT, Cui X, Reckamp K, et al. Chemoprevention strategies with cyclooxygenase-2 inhibitors for lung cancer. Clin Lung Cancer 2005;7:30-9.
-
(2005)
Clin Lung Cancer
, vol.7
, pp. 30-39
-
-
Mao, J.T.1
Cui, X.2
Reckamp, K.3
-
10
-
-
0037440560
-
Abnormal interleukin 10Rα expression contributes to the maintenance of elevated cyclooxygenase-2 in nonsmall cell lung cancer cells
-
Heuze-Vourc'h N, Zhu L, Krysan K, et al. Abnormal interleukin 10Rα expression contributes to the maintenance of elevated cyclooxygenase-2 in nonsmall cell lung cancer cells. Cancer Res 2003;63: 766-70.
-
(2003)
Cancer Res
, vol.63
, pp. 766-770
-
-
Heuze-Vourc'H, N.1
Zhu, L.2
Krysan, K.3
-
11
-
-
34250858021
-
Unphosphorylated STAT6 contributes to constitutive cyclooxygenase- 2 expression in human non-small cell lung cancer
-
Cui X, Zhang L, Luo J, et al. Unphosphorylated STAT6 contributes to constitutive cyclooxygenase- 2 expression in human non-small cell lung cancer. Oncogene 2007;26:4253-60.
-
(2007)
Oncogene
, vol.26
, pp. 4253-4260
-
-
Cui, X.1
Zhang, L.2
Luo, J.3
-
12
-
-
0141844522
-
Regulation of cyclooxgenase-2 mRNAstabili ty by taxanes: Evidence for involvement of p38, MAPKAPK-2, and HuR
-
Subbaramaiah K, Marmo TP, Dixon DA, et al. Regulation of cyclooxgenase-2 mRNAstabili ty by taxanes: evidence for involvement of p38, MAPKAPK-2, and HuR. J Biol Chem 2003;278: 37637-47.
-
(2003)
J Biol Chem
, vol.278
, pp. 37637-37647
-
-
Subbaramaiah, K.1
Marmo, T.P.2
Dixon, D.A.3
-
13
-
-
1342310807
-
COX-2- dependent stabilization of survivin in non-small cell lung cancer
-
Krysan K, Merchant FH, Zhu L, et al. COX-2- dependent stabilization of survivin in non-small cell lung cancer. FASEB J 2004;18:206-8.
-
(2004)
FASEB J
, vol.18
, pp. 206-208
-
-
Krysan, K.1
Merchant, F.H.2
Zhu, L.3
-
14
-
-
4644289318
-
Cyclooxygenase- 2 modulates the insulin-like growth factor axis in non-small-cell lung cancer
-
Pold M, Krysan K, Pold A, et al. Cyclooxygenase- 2 modulates the insulin-like growth factor axis in non-small-cell lung cancer. Cancer Res 2004;64: 6549-55.
-
(2004)
Cancer Res
, vol.64
, pp. 6549-6555
-
-
Pold, M.1
Krysan, K.2
Pold, A.3
-
15
-
-
0037343236
-
Tumor cyclooxygenase 2-dependent suppression of dendritic cell function
-
Sharma S, Stolina M, Yang SC, et al. Tumor cyclooxygenase 2-dependent suppression of dendritic cell function. Clin Cancer Res 2003;9:961-8.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 961-968
-
-
Sharma, S.1
Stolina, M.2
Yang, S.C.3
-
16
-
-
12144291145
-
Cyclooxygenase- 2-dependent expression of angiogenic CXC chemokines ENA-78/CXC Ligand (CXCL) 5 and interleukin-8/CXCL8 in human non-small cell lung cancer
-
Pold M, Zhu LX, Sharma S, et al. Cyclooxygenase- 2-dependent expression of angiogenic CXC chemokines ENA-78/CXC Ligand (CXCL) 5 and interleukin-8/CXCL8 in human non-small cell lung cancer. Cancer Res 2004;64:1853-60.
-
(2004)
Cancer Res
, vol.64
, pp. 1853-1860
-
-
Pold, M.1
Zhu, L.X.2
Sharma, S.3
-
17
-
-
0346736504
-
2 production by nonsmall cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase- 2-dependent invasion
-
Dohadwala M, Batra RK, Luo J, et al. Autocrine/ paracrine prostaglandin E2 production by nonsmall cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase- 2-dependent invasion. J Biol Chem 2002;277: 50828-33.
-
(2002)
J Biol Chem
, vol.277
, pp. 50828-50833
-
-
Dohadwala, M.1
Batra, R.K.2
Luo, J.3
-
18
-
-
33744925683
-
Cyclooxygenase- 2-dependent regulation of E-cadherin: Prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer
-
Dohadwala M, Yang SC, Luo J, et al. Cyclooxygenase- 2-dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer. Cancer Res 2006;66:5338-45.
-
(2006)
Cancer Res
, vol.66
, pp. 5338-5345
-
-
Dohadwala, M.1
Yang, S.C.2
Luo, J.3
-
19
-
-
31544467105
-
Celecoxib decreases Ki-67 proliferative index in active smokers
-
Mao JT, Fishbein MC, Adams B, et al. Celecoxib decreases Ki-67 proliferative index in active smokers. Clin Cancer Res 2006;12:314-20.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 314-320
-
-
Mao, J.T.1
Fishbein, M.C.2
Adams, B.3
-
20
-
-
64049107388
-
Arandomized doubleblind study of the biological effects of celecoxib as a chemoprevention agent in current and former smokers
-
May 20
-
Kim E, Hong W, Lee J, et al. Arandomized doubleblind study of the biological effects of celecoxib as a chemoprevention agent in current and former smokers. J Clin Oncol 2008. May 20 suppl.
-
(2008)
J Clin Oncol
, Issue.SUPPL.
-
-
Kim, E.1
Hong, W.2
Lee, J.3
-
21
-
-
0036468255
-
Manipulation of pulmonary prostacyclin synthase expression prevents murine lung cancer
-
Keith RL, Miller YE, Hoshikawa Y, et al. Manipulation of pulmonary prostacyclin synthase expression prevents murine lung cancer. Cancer Res 2002;62:734-40.
-
(2002)
Cancer Res
, vol.62
, pp. 734-740
-
-
Keith, R.L.1
Miller, Y.E.2
Hoshikawa, Y.3
-
22
-
-
6044256286
-
Modulation of pulmonary leukotriene B4 production by cyclooxygenase- 2 inhibitors and lipopolysaccharide
-
Mao JT, Tsu IH, Dubinett SM, et al. Modulation of pulmonary leukotriene B4 production by cyclooxygenase- 2 inhibitors and lipopolysaccharide. Clin Cancer Res 2004;10:6872-8.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 6872-6878
-
-
Mao, J.T.1
Tsu, I.H.2
Dubinett, S.M.3
-
23
-
-
34047105383
-
NSAIDs and cancer prevention: Targets downstream of COX-2
-
Cha Y, DuBois R. NSAIDs and cancer prevention: targets downstream of COX-2. Annu Rev Med 2007;58:239-52.
-
(2007)
Annu Rev Med
, vol.58
, pp. 239-252
-
-
Cha, Y.1
Dubois, R.2
-
24
-
-
0034018418
-
Structurefunction analyses of eicosanoid receptors. Physiologic and therapeutic implications
-
Breyer R, Kennedy C, Zhang Y, et al. Structurefunction analyses of eicosanoid receptors. Physiologic and therapeutic implications. Ann N Y Acad Sci 2000;905:221-31.
-
(2000)
Ann N y Acad Sci
, vol.905
, pp. 221-231
-
-
Breyer, R.1
Kennedy, C.2
Zhang, Y.3
-
25
-
-
33750308463
-
Host and direct antitumor effects and profound reduction in tumor metastasis with selective EP4 receptor antagonism
-
Yang L, Huang Y, Porta R, et al. Host and direct antitumor effects and profound reduction in tumor metastasis with selective EP4 receptor antagonism. Cancer Res 2006;66:9665-72.
-
(2006)
Cancer Res
, vol.66
, pp. 9665-9672
-
-
Yang, L.1
Huang, Y.2
Porta, R.3
-
26
-
-
34247241559
-
2 receptor subtype EP4 in lung carcinoma cells through multiple signaling pathways: The role of AP-2
-
2 receptor subtype EP4 in lung carcinoma cells through multiple signaling pathways: the role of AP-2. J Biol Chem 2007;282:7961-72.
-
(2007)
J Biol Chem
, vol.282
, pp. 7961-7972
-
-
Han, S.1
Ritzenthaler, J.D.2
Wingerd, B.3
-
27
-
-
22244467085
-
2 activates mitogen-activated protein kinase/ Erk pathway signaling and cell proliferation in non-small cell lung cancer cells in an epidermal growth factor receptor-independent manner
-
2 activates mitogen-activated protein kinase/ Erk pathway signaling and cell proliferation in non-small cell lung cancer cells in an epidermal growth factor receptor-independent manner. Cancer Res 2005;65:6275-81.
-
(2005)
Cancer Res
, vol.65
, pp. 6275-6281
-
-
Krysan, K.1
Reckamp, K.L.2
Dalwadi, H.3
-
28
-
-
13444269594
-
NAD+-linked 15- hydroxyprostaglandin dehydrogenase (15-PGDH) behaves as a tumor suppressor in lung cancer
-
Ding Y, Tong M, Liu S, et al. NAD+-linked 15- hydroxyprostaglandin dehydrogenase (15-PGDH) behaves as a tumor suppressor in lung cancer. Carcinogenesis 2005;26:65-72.
-
(2005)
Carcinogenesis
, vol.26
, pp. 65-72
-
-
Ding, Y.1
Tong, M.2
Liu, S.3
-
29
-
-
33747873279
-
15-Hydroxyprostaglandin dehydrogenase is a tumor suppressor of human breast cancer
-
Wolf I, O'Kelly J, Rubinek T, et al. 15-Hydroxyprostaglandin dehydrogenase is a tumor suppressor of human breast cancer. Cancer Res 2006;66:7818-23.
-
(2006)
Cancer Res
, vol.66
, pp. 7818-7823
-
-
Wolf, I.1
O'Kelly, J.2
Rubinek, T.3
-
30
-
-
0036893004
-
Inhibition of NAD+-dependent 15- hydroxyprostaglandin dehydrogenase (15-PGDH) by cyclooxygenase inhibitors and chemopreventive agents
-
Cho H, Tai HH. Inhibition of NAD+-dependent 15- hydroxyprostaglandin dehydrogenase (15-PGDH) by cyclooxygenase inhibitors and chemopreventive agents. Prostaglandins Leukot Essent Fatty Acids 2002;67:461-5.
-
(2002)
Prostaglandins Leukot Essent Fatty Acids
, vol.67
, pp. 461-465
-
-
Cho, H.1
Tai, H.H.2
-
31
-
-
34547101243
-
2 catabolism in regulation of peroxisome proliferator-activated receptor γ activation
-
2 catabolism in regulation of peroxisome proliferator-activated receptor γ activation. J Biol Chem 2007;282: 18162-72.
-
(2007)
J Biol Chem
, vol.282
, pp. 18162-18172
-
-
Chou, W.L.1
Chuang, L.M.2
Chou, C.C.3
-
32
-
-
57249089707
-
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase regulates levels of bioactive lipids in non-small cell lung cancer
-
Hughes D, Otani T, Yang P, et al. NAD+-dependent 15-hydroxyprostaglandin dehydrogenase regulates levels of bioactive lipids in non-small cell lung cancer. Cancer Prev Res 2008.
-
(2008)
Cancer Prev Res
-
-
Hughes, D.1
Otani, T.2
Yang, P.3
-
33
-
-
48549087414
-
15-Hydroxyprostaglandin dehydrogenase is a target of hepatocyte nuclear factor 3β and a tumor suppressor in lung cancer
-
Huang G, Eisenberg R, Yan M, et al. 15-Hydroxyprostaglandin dehydrogenase is a target of hepatocyte nuclear factor 3β and a tumor suppressor in lung cancer. Cancer Res 2008;68:5040-8.
-
(2008)
Cancer Res
, vol.68
, pp. 5040-5048
-
-
Huang, G.1
Eisenberg, R.2
Yan, M.3
-
34
-
-
34250815766
-
Inhibition of epidermal growth factor receptor signaling elevates 15-hydroxyprostaglandin dehydrogenase in non-small-cell lung cancer
-
Yang L, Amann JM, Kikuchi T, et al. Inhibition of epidermal growth factor receptor signaling elevates 15-hydroxyprostaglandin dehydrogenase in non-small-cell lung cancer. Cancer Res 2007;67: 5587-93.
-
(2007)
Cancer Res
, vol.67
, pp. 5587-5593
-
-
Yang, L.1
Amann, J.M.2
Kikuchi, T.3
-
35
-
-
84900651979
-
Inflammation-dependent regulation of epithelialmesenchymal transition in non-small cell lung cancer: The role of interleukin-1β
-
Heinrich E, Dohadwala M, Charuworn B, et al. Inflammation-dependent regulation of epithelialmesenchymal transition in non-small cell lung cancer: the role of interleukin-1β. Proc A m Assoc Cancer Res 2008;5366.
-
(2008)
Proc A M Assoc Cancer Res
, pp. 5366
-
-
Heinrich, E.1
Dohadwala, M.2
Charuworn, B.3
-
36
-
-
0033594963
-
Identification of human prostaglandin e synthase: A microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target
-
Jakobsson PJ, Thoren S, Morgenstern R, et al. Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target. Proc Natl Acad Sci U S A 1999;96:7220-5.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 7220-7225
-
-
Jakobsson, P.J.1
Thoren, S.2
Morgenstern, R.3
-
37
-
-
44349148410
-
Mutations in 15-hydroxyprostaglandin dehydrogenase cause primary hypertrophic osteoarthropathy
-
Uppal S, Diggle CP, Carr IM, et al. Mutations in 15-hydroxyprostaglandin dehydrogenase cause primary hypertrophic osteoarthropathy. Nat Genet 2008;40:789-93.
-
(2008)
Nat Genet
, vol.40
, pp. 789-793
-
-
Uppal, S.1
Diggle, C.P.2
Carr, I.M.3
-
38
-
-
0014944305
-
Inactivation of prostaglandins by the lungs
-
Piper PJ, Vane JR, Wyllie JH. Inactivation of prostaglandins by the lungs. Nature 1970;225:600-4.
-
(1970)
Nature
, vol.225
, pp. 600-604
-
-
Piper, P.J.1
Vane, J.R.2
Wyllie, J.H.3
-
39
-
-
44349168815
-
The Hippocratic finger points the blame at PGE2
-
Coggins KG, Coffman TM, Koller BH. The Hippocratic finger points the blame at PGE2. Nat Genet 2008;40:691-2.
-
(2008)
Nat Genet
, vol.40
, pp. 691-692
-
-
Coggins, K.G.1
Coffman, T.M.2
Koller, B.H.3
-
40
-
-
34248658800
-
Exploring the cause of the most ancient clinical sign of medicine: Finger clubbing
-
Lavin-Martinez M. Exploring the cause of the most ancient clinical sign of medicine: finger clubbing. Semin Arthritis Rheum 2007;36:380-5.
-
(2007)
Semin Arthritis Rheum
, vol.36
, pp. 380-385
-
-
Lavin-Martinez, M.1
-
41
-
-
34247519066
-
15-Hydroxyprostaglandin dehydrogenase (15-PGDH) and lung cancer
-
Tai HH, Tong M, Ding Y. 15-Hydroxyprostaglandin dehydrogenase (15-PGDH) and lung cancer. Prostaglandins Other Lipid Mediat 2007;83:203-8.
-
(2007)
Prostaglandins Other Lipid Mediat
, vol.83
, pp. 203-208
-
-
Tai, H.H.1
Tong, M.2
Ding, Y.3
-
42
-
-
33747184291
-
Histone deacetylase inhibitors and transforming growth factor-β induce 15-hydroxyprostaglandin dehydrogenase expression in human lung adenocarcinoma cells
-
Tong M, Ding Y, Tai HH. Histone deacetylase inhibitors and transforming growth factor-β induce 15-hydroxyprostaglandin dehydrogenase expression in human lung adenocarcinoma cells. Biochem Pharmacol 2006;72:701-9.
-
(2006)
Biochem Pharmacol
, vol.72
, pp. 701-709
-
-
Tong, M.1
Ding, Y.2
Tai, H.H.3
-
43
-
-
34347353320
-
2 in nonsmall- cell lung cancer cells by up-regulating 15-hydroxyprostaglandin dehydrogenase
-
2 in nonsmall- cell lung cancer cells by up-regulating 15-hydroxyprostaglandin dehydrogenase. Mol Pharmacol 2007;71:1715-20.
-
(2007)
Mol Pharmacol
, vol.71
, pp. 1715-1720
-
-
Hazra, S.1
Batra, R.K.2
Tai, H.H.3
-
44
-
-
57249086646
-
Regulation of prostaglandin transporters in colorectal neoplasia
-
Holla V, Backlund M, Yang P, et al. Regulation of prostaglandin transporters in colorectal neoplasia. Cancer Prev Res 2008;1:93-9.
-
(2008)
Cancer Prev Res
, vol.1
, pp. 93-99
-
-
Holla, V.1
Backlund, M.2
Yang, P.3
|