메뉴 건너뛰기




Volumn 81, Issue 1, 2009, Pages 9-15

Leukotriene pathway polymorphisms are associated with altered cysteinyl leukotriene production in children with acute asthma

Author keywords

Acute asthma; Childhood; Leukotriene; Single nucleotide polymorphism

Indexed keywords

ADENINE; ARACHIDONATE 5 LIPOXYGENASE ACTIVATING PROTEIN; CREATININE; CYTOSINE; GENE PRODUCT; GLUTATHIONE PEROXIDASE; GLUTATHIONE PEROXIDASE 4; GUANINE; IPRATROPIUM BROMIDE; LEUKOTRIENE C4; LEUKOTRIENE E4; PEPTIDOLEUKOTRIENE; PREDNISOLONE; PROTEIN ALOX5; PROTEIN CYSTLTR1; SALBUTAMOL; THYMIDINE; UNCLASSIFIED DRUG;

EID: 67649449334     PISSN: 09523278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.plefa.2009.05.022     Document Type: Article
Times cited : (19)

References (44)
  • 1
    • 0019254822 scopus 로고
    • Leukotrienes are potent constrictors of human bronchi
    • Dahlen S.E., Hedqvist P., Hammarstrom S., and Samuelsson B. Leukotrienes are potent constrictors of human bronchi. Nature 288 5790 (1980) 484-486
    • (1980) Nature , vol.288 , Issue.5790 , pp. 484-486
    • Dahlen, S.E.1    Hedqvist, P.2    Hammarstrom, S.3    Samuelsson, B.4
  • 2
    • 3242807236 scopus 로고    scopus 로고
    • Cysteinyl leukotrienes and their receptors: cellular distribution and function in immune and inflammatory responses
    • Kanaoka Y., and Boyce J.A. Cysteinyl leukotrienes and their receptors: cellular distribution and function in immune and inflammatory responses. J. Immunol. 173 3 (2004) 1503-1510
    • (2004) J. Immunol. , vol.173 , Issue.3 , pp. 1503-1510
    • Kanaoka, Y.1    Boyce, J.A.2
  • 3
    • 12144267623 scopus 로고    scopus 로고
    • Leukotrienes: underappreciated mediators of innate immune responses
    • Peters-Golden M., Canetti C., Mancuso P., and Coffey M.J. Leukotrienes: underappreciated mediators of innate immune responses. J. Immunol. 174 2 (2005) 589-594
    • (2005) J. Immunol. , vol.174 , Issue.2 , pp. 589-594
    • Peters-Golden, M.1    Canetti, C.2    Mancuso, P.3    Coffey, M.J.4
  • 4
    • 0025164256 scopus 로고
    • Leukotrienes and other products of the 5-lipoxygenase pathway. Biochemistry and relation to pathobiology in human diseases
    • Lewis R.A., Austen K.F., and Soberman R.J. Leukotrienes and other products of the 5-lipoxygenase pathway. Biochemistry and relation to pathobiology in human diseases. N. Engl. J. Med. 323 10 (1990) 645-655
    • (1990) N. Engl. J. Med. , vol.323 , Issue.10 , pp. 645-655
    • Lewis, R.A.1    Austen, K.F.2    Soberman, R.J.3
  • 5
    • 1242351725 scopus 로고    scopus 로고
    • Increase in urinary leukotriene LTE4 levels in acute asthma: correlation with airflow limitation
    • Green S.A., Malice M.P., Tanaka W., Tozzi C.A., and Reiss T.F. Increase in urinary leukotriene LTE4 levels in acute asthma: correlation with airflow limitation. Thorax 59 2 (2004) 100-104
    • (2004) Thorax , vol.59 , Issue.2 , pp. 100-104
    • Green, S.A.1    Malice, M.P.2    Tanaka, W.3    Tozzi, C.A.4    Reiss, T.F.5
  • 6
    • 23944435385 scopus 로고    scopus 로고
    • Urine leukotriene E and eosinophil cationic protein in nasopharyngeal aspiration from young wheezy children
    • Oh J.W., Shin S.A., and Lee H.B. Urine leukotriene E and eosinophil cationic protein in nasopharyngeal aspiration from young wheezy children. Pediatr. Allergy Immunol. 16 5 (2005) 416-421
    • (2005) Pediatr. Allergy Immunol. , vol.16 , Issue.5 , pp. 416-421
    • Oh, J.W.1    Shin, S.A.2    Lee, H.B.3
  • 7
    • 0033772785 scopus 로고    scopus 로고
    • Urinary excretion of leukotriene E4 and eosinophil protein X in children with atopic asthma
    • Severien C., Artlich A., Jonas S., and Becher G. Urinary excretion of leukotriene E4 and eosinophil protein X in children with atopic asthma. Eur. Respir. J. 16 4 (2000) 588-592
    • (2000) Eur. Respir. J. , vol.16 , Issue.4 , pp. 588-592
    • Severien, C.1    Artlich, A.2    Jonas, S.3    Becher, G.4
  • 8
    • 0033787420 scopus 로고    scopus 로고
    • Difference in urinary LTE4 and 11-dehydro-TXB2 excretion in asthmatic patients
    • Suzuki N., Hishinuma T., Abe F., et al. Difference in urinary LTE4 and 11-dehydro-TXB2 excretion in asthmatic patients. Prostaglandins Other Lipid Mediat. 62 4 (2000) 395-403
    • (2000) Prostaglandins Other Lipid Mediat. , vol.62 , Issue.4 , pp. 395-403
    • Suzuki, N.1    Hishinuma, T.2    Abe, F.3
  • 9
    • 0026644731 scopus 로고
    • Urinary excretion of leukotriene E4 and 11-dehydro-thromboxane B2 in response to bronchial provocations with allergen, aspirin, leukotriene D4, and histamine in asthmatics
    • Kumlin M., Dahlen B., Bjorck T., Zetterstrom O., Granstrom E., and Dahlen S.E. Urinary excretion of leukotriene E4 and 11-dehydro-thromboxane B2 in response to bronchial provocations with allergen, aspirin, leukotriene D4, and histamine in asthmatics. Am. Rev. Respir. Dis. 146 1 (1992) 96-103
    • (1992) Am. Rev. Respir. Dis. , vol.146 , Issue.1 , pp. 96-103
    • Kumlin, M.1    Dahlen, B.2    Bjorck, T.3    Zetterstrom, O.4    Granstrom, E.5    Dahlen, S.E.6
  • 10
    • 0042355703 scopus 로고    scopus 로고
    • Recent advances in the management of asthma using leukotriene modifiers
    • Kemp J.P. Recent advances in the management of asthma using leukotriene modifiers. Am. J. Respir. Med. 2 2 (2003) 139-156
    • (2003) Am. J. Respir. Med. , vol.2 , Issue.2 , pp. 139-156
    • Kemp, J.P.1
  • 11
    • 2942689443 scopus 로고    scopus 로고
    • Leukotriene receptor antagonists-risks and benefits for use in paediatric asthma
    • Spahr J.E., and Krawiec M.E. Leukotriene receptor antagonists-risks and benefits for use in paediatric asthma. Expert Opin. Drug Saf. 3 3 (2004) 173-185
    • (2004) Expert Opin. Drug Saf. , vol.3 , Issue.3 , pp. 173-185
    • Spahr, J.E.1    Krawiec, M.E.2
  • 12
    • 0031891264 scopus 로고    scopus 로고
    • Glutathione peroxidase activity and mRNA expression in eosinophils and neutrophils of asthmatic and non-asthmatic subjects
    • Misso N.L., Peroni D.J., Watkins D.N., Stewart G.A., and Thompson P.J. Glutathione peroxidase activity and mRNA expression in eosinophils and neutrophils of asthmatic and non-asthmatic subjects. J. Leukoc. Biol. 63 1 (1998) 124-130
    • (1998) J. Leukoc. Biol. , vol.63 , Issue.1 , pp. 124-130
    • Misso, N.L.1    Peroni, D.J.2    Watkins, D.N.3    Stewart, G.A.4    Thompson, P.J.5
  • 13
    • 0033600291 scopus 로고    scopus 로고
    • Characterization of the human cysteinyl leukotriene CysLT1 receptor
    • Lynch K.R., O'Neill G.P., Liu Q., et al. Characterization of the human cysteinyl leukotriene CysLT1 receptor. Nature 399 6738 (1999) 789-793
    • (1999) Nature , vol.399 , Issue.6738 , pp. 789-793
    • Lynch, K.R.1    O'Neill, G.P.2    Liu, Q.3
  • 14
    • 0033156390 scopus 로고    scopus 로고
    • Novel polymorphism of the 5-lipoxygenase activating protein (FLAP) promoter gene associated with asthma
    • Koshino T., Takano S., Kitani S., et al. Novel polymorphism of the 5-lipoxygenase activating protein (FLAP) promoter gene associated with asthma. Mol. Cell Biol. Res. Commun. 2 1 (1999) 32-35
    • (1999) Mol. Cell Biol. Res. Commun. , vol.2 , Issue.1 , pp. 32-35
    • Koshino, T.1    Takano, S.2    Kitani, S.3
  • 15
    • 2342642716 scopus 로고    scopus 로고
    • Characterization of two polymorphisms in the leukotriene C4 synthase gene in an Australian population of subjects with mild, moderate, and severe asthma
    • Kedda M.A., Shi J., Duffy D., et al. Characterization of two polymorphisms in the leukotriene C4 synthase gene in an Australian population of subjects with mild, moderate, and severe asthma. J. Allergy Clin. Immunol. 113 5 (2004) 889-895
    • (2004) J. Allergy Clin. Immunol. , vol.113 , Issue.5 , pp. 889-895
    • Kedda, M.A.1    Shi, J.2    Duffy, D.3
  • 16
    • 0033803781 scopus 로고    scopus 로고
    • Variant LTC(4) synthase allele modifies cysteinyl leukotriene synthesis in eosinophils and predicts clinical response to zafirlukast
    • Sampson A.P., Siddiqui S., Buchanan D., et al. Variant LTC(4) synthase allele modifies cysteinyl leukotriene synthesis in eosinophils and predicts clinical response to zafirlukast. Thorax 55 Suppl. 2 (2000) S28-S31
    • (2000) Thorax , vol.55 , Issue.SUPPL. 2
    • Sampson, A.P.1    Siddiqui, S.2    Buchanan, D.3
  • 17
    • 0033059209 scopus 로고    scopus 로고
    • Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment
    • Drazen J.M., Yandava C.N., Dube L., et al. Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment. Nat. Genet. 22 2 (1999) 168-170
    • (1999) Nat. Genet. , vol.22 , Issue.2 , pp. 168-170
    • Drazen, J.M.1    Yandava, C.N.2    Dube, L.3
  • 18
    • 18644372214 scopus 로고    scopus 로고
    • Leukotriene C4 synthase gene A(-444)C polymorphism and clinical response to a CYS-LT(1) antagonist, pranlukast, in Japanese patients with moderate asthma
    • Asano K., Shiomi T., Hasegawa N., et al. Leukotriene C4 synthase gene A(-444)C polymorphism and clinical response to a CYS-LT(1) antagonist, pranlukast, in Japanese patients with moderate asthma. Pharmacogenetics 12 7 (2002) 565-570
    • (2002) Pharmacogenetics , vol.12 , Issue.7 , pp. 565-570
    • Asano, K.1    Shiomi, T.2    Hasegawa, N.3
  • 19
    • 1542375439 scopus 로고    scopus 로고
    • Leukotriene-related gene polymorphisms in ASA-intolerant asthma: an association with a haplotype of 5-lipoxygenase
    • Choi J.H., Park H.S., Oh H.B., et al. Leukotriene-related gene polymorphisms in ASA-intolerant asthma: an association with a haplotype of 5-lipoxygenase. Hum. Genet. 114 4 (2004) 337-344
    • (2004) Hum. Genet. , vol.114 , Issue.4 , pp. 337-344
    • Choi, J.H.1    Park, H.S.2    Oh, H.B.3
  • 20
    • 0033827946 scopus 로고    scopus 로고
    • Enhanced expression of the leukotriene C(4) synthase due to overactive transcription of an allelic variant associated with aspirin-intolerant asthma
    • Sanak M., Pierzchalska M., Bazan-Socha S., and Szczeklik A. Enhanced expression of the leukotriene C(4) synthase due to overactive transcription of an allelic variant associated with aspirin-intolerant asthma. Am. J. Respir. Cell Mol. Biol. 23 3 (2000) 290-296
    • (2000) Am. J. Respir. Cell Mol. Biol. , vol.23 , Issue.3 , pp. 290-296
    • Sanak, M.1    Pierzchalska, M.2    Bazan-Socha, S.3    Szczeklik, A.4
  • 21
    • 0031590522 scopus 로고    scopus 로고
    • Leukotriene C4 synthase promoter polymorphism and risk of aspirin-induced asthma
    • Sanak M., Simon H.U., and Szczeklik A. Leukotriene C4 synthase promoter polymorphism and risk of aspirin-induced asthma. Lancet 350 9091 (1997) 1599-1600
    • (1997) Lancet , vol.350 , Issue.9091 , pp. 1599-1600
    • Sanak, M.1    Simon, H.U.2    Szczeklik, A.3
  • 22
    • 0036399163 scopus 로고    scopus 로고
    • A novel single nucleotide polymorphism in the 3' untranslated region of human glutathione peroxidase 4 influences lipoxygenase metabolism
    • Villette S., Kyle J.A., Brown K.M., et al. A novel single nucleotide polymorphism in the 3' untranslated region of human glutathione peroxidase 4 influences lipoxygenase metabolism. Blood Cells Mol. Dis. 29 2 (2002) 174-178
    • (2002) Blood Cells Mol. Dis. , vol.29 , Issue.2 , pp. 174-178
    • Villette, S.1    Kyle, J.A.2    Brown, K.M.3
  • 23
    • 0033393252 scopus 로고    scopus 로고
    • Time-course study of the levels of urinary leukotriene E4, serum thromboxane B2 and serum eosinophil cationic protein in spontaneous asthma attacks in five children
    • Inoue R., Fukao T., Kato Y., Teramoto T., Utsumi M., and Kondo N. Time-course study of the levels of urinary leukotriene E4, serum thromboxane B2 and serum eosinophil cationic protein in spontaneous asthma attacks in five children. J. Invest. Allergol. Clin. Immunol. 9 6 (1999) 361-366
    • (1999) J. Invest. Allergol. Clin. Immunol. , vol.9 , Issue.6 , pp. 361-366
    • Inoue, R.1    Fukao, T.2    Kato, Y.3    Teramoto, T.4    Utsumi, M.5    Kondo, N.6
  • 24
    • 0029099139 scopus 로고
    • Persistent increase in plasma and urinary leukotrienes after acute asthma
    • Sampson A.P., Castling D.P., Green C.P., and Price J.F. Persistent increase in plasma and urinary leukotrienes after acute asthma. Arch. Dis. Child 73 3 (1995) 221-225
    • (1995) Arch. Dis. Child , vol.73 , Issue.3 , pp. 221-225
    • Sampson, A.P.1    Castling, D.P.2    Green, C.P.3    Price, J.F.4
  • 25
    • 33644885331 scopus 로고    scopus 로고
    • ALOX5 promoter genotype, asthma severity and LTC production by eosinophils
    • Kalayci O., Birben E., Sackesen C., et al. ALOX5 promoter genotype, asthma severity and LTC production by eosinophils. Allergy 61 1 (2006) 97-103
    • (2006) Allergy , vol.61 , Issue.1 , pp. 97-103
    • Kalayci, O.1    Birben, E.2    Sackesen, C.3
  • 26
    • 0042121509 scopus 로고    scopus 로고
    • Promoter polymorphism in the 5-lipoxygenase (ALOX5) and 5-lipoxygenase-activating protein (ALOX5AP) genes and asthma susceptibility in a Caucasian population
    • Sayers I., Barton S., Rorke S., et al. Promoter polymorphism in the 5-lipoxygenase (ALOX5) and 5-lipoxygenase-activating protein (ALOX5AP) genes and asthma susceptibility in a Caucasian population. Clin. Exp. Allergy 33 8 (2003) 1103-1110
    • (2003) Clin. Exp. Allergy , vol.33 , Issue.8 , pp. 1103-1110
    • Sayers, I.1    Barton, S.2    Rorke, S.3
  • 27
    • 0031003816 scopus 로고    scopus 로고
    • Naturally occurring mutations in the human 5-lipoxygenase gene promoter that modify transcription factor binding and reporter gene transcription
    • In K.H., Asano K., Beier D., et al. Naturally occurring mutations in the human 5-lipoxygenase gene promoter that modify transcription factor binding and reporter gene transcription. J. Clin. Invest. 99 5 (1997) 1130-1137
    • (1997) J. Clin. Invest. , vol.99 , Issue.5 , pp. 1130-1137
    • In, K.H.1    Asano, K.2    Beier, D.3
  • 28
    • 0038366908 scopus 로고    scopus 로고
    • Allelic association and functional studies of promoter polymorphism in the leukotriene C4 synthase gene (LTC4S) in asthma
    • Sayers I., Barton S., Rorke S., et al. Allelic association and functional studies of promoter polymorphism in the leukotriene C4 synthase gene (LTC4S) in asthma. Thorax 58 5 (2003) 417-424
    • (2003) Thorax , vol.58 , Issue.5 , pp. 417-424
    • Sayers, I.1    Barton, S.2    Rorke, S.3
  • 29
    • 33644848487 scopus 로고    scopus 로고
    • Acute asthma in children: Relationships among CD14 and CC16 genotypes, plasma levels, and severity
    • Martin A.C., Laing I.A., Khoo S.K., et al. Acute asthma in children: Relationships among CD14 and CC16 genotypes, plasma levels, and severity. Am. J. Respir. Crit. Care Med. 173 6 (2006) 617-622
    • (2006) Am. J. Respir. Crit. Care Med. , vol.173 , Issue.6 , pp. 617-622
    • Martin, A.C.1    Laing, I.A.2    Khoo, S.K.3
  • 31
    • 0025793465 scopus 로고
    • The influence of a family history of asthma and parental smoking on airway responsiveness in early infancy
    • Young S., Le Souef P.N., Geelhoed G.C., Stick S.M., Turner K.J., and Landau L.I. The influence of a family history of asthma and parental smoking on airway responsiveness in early infancy. N. Engl. J. Med. 324 17 (1991) 1168-1173
    • (1991) N. Engl. J. Med. , vol.324 , Issue.17 , pp. 1168-1173
    • Young, S.1    Le Souef, P.N.2    Geelhoed, G.C.3    Stick, S.M.4    Turner, K.J.5    Landau, L.I.6
  • 32
    • 0032497502 scopus 로고    scopus 로고
    • Effect of nebulized ipratropium on the hospitalization rates of children with asthma
    • Qureshi F., Pestian J., Davis P., and Zaritsky A. Effect of nebulized ipratropium on the hospitalization rates of children with asthma. N. Engl. J. Med. 339 15 (1998) 1030-1035
    • (1998) N. Engl. J. Med. , vol.339 , Issue.15 , pp. 1030-1035
    • Qureshi, F.1    Pestian, J.2    Davis, P.3    Zaritsky, A.4
  • 33
    • 0024284028 scopus 로고
    • A simple salting out procedure for extracting DNA from human nucleated cells
    • Miller S.A., Dykes D.D., and Polesky H.F. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 16 3 (1988) 1215
    • (1988) Nucleic Acids Res. , vol.16 , Issue.3 , pp. 1215
    • Miller, S.A.1    Dykes, D.D.2    Polesky, H.F.3
  • 35
    • 2042476057 scopus 로고    scopus 로고
    • Urinary leukotriene E4 and 9 alpha, 11 beta-prostaglandin F concentrations in mild, moderate and severe asthma, and in healthy subjects
    • Misso N.L., Aggarwal S., Phelps S., Beard R., and Thompson P.J. Urinary leukotriene E4 and 9 alpha, 11 beta-prostaglandin F concentrations in mild, moderate and severe asthma, and in healthy subjects. Clin. Exp. Allergy 34 4 (2004) 624-631
    • (2004) Clin. Exp. Allergy , vol.34 , Issue.4 , pp. 624-631
    • Misso, N.L.1    Aggarwal, S.2    Phelps, S.3    Beard, R.4    Thompson, P.J.5
  • 36
    • 0029063425 scopus 로고
    • Validation and application of a new simple strategy for measurements of urinary leukotriene E4 in humans
    • Kumlin M., Stensvad F., Larsson L., Dahlen B., and Dahlen S.E. Validation and application of a new simple strategy for measurements of urinary leukotriene E4 in humans. Clin. Exp. Allergy 25 5 (1995) 467-479
    • (1995) Clin. Exp. Allergy , vol.25 , Issue.5 , pp. 467-479
    • Kumlin, M.1    Stensvad, F.2    Larsson, L.3    Dahlen, B.4    Dahlen, S.E.5
  • 37
    • 33745657223 scopus 로고    scopus 로고
    • J.W. Holloway. The cysteinyl-leukotriene type 1 receptor polymorphism 927T/C is associated with atopy severity but not with asthma
    • Hao L., Sawyers I., Cakebread J.A., Barton S.J., Beghe B., Holgate S.T., and Sampson A.P. J.W. Holloway. The cysteinyl-leukotriene type 1 receptor polymorphism 927T/C is associated with atopy severity but not with asthma. Clin. Exp. Allergy 36 6 (2006) 735-741
    • (2006) Clin. Exp. Allergy , vol.36 , Issue.6 , pp. 735-741
    • Hao, L.1    Sawyers, I.2    Cakebread, J.A.3    Barton, S.J.4    Beghe, B.5    Holgate, S.T.6    Sampson, A.P.7
  • 38
    • 57749117438 scopus 로고    scopus 로고
    • Analysis of 927, T>C CYSLTR1 and -444A >C LTC4S polymorphisms in children with asthma
    • Arriba-Mendez S., Sanz C., Isidoro-Garcia M., et al. Analysis of 927, T>C CYSLTR1 and -444A >C LTC4S polymorphisms in children with asthma. Allergol. Immunopathol. (Madr.) 36 5 (2008) 259-263
    • (2008) Allergol. Immunopathol. (Madr.) , vol.36 , Issue.5 , pp. 259-263
    • Arriba-Mendez, S.1    Sanz, C.2    Isidoro-Garcia, M.3
  • 39
    • 0037246669 scopus 로고    scopus 로고
    • Urinary leukotriene E4 in preschool children with acute clinical viral wheeze
    • Oommen A., and Grigg J. Urinary leukotriene E4 in preschool children with acute clinical viral wheeze. Eur. Respir. J. 21 1 (2003) 149-154
    • (2003) Eur. Respir. J. , vol.21 , Issue.1 , pp. 149-154
    • Oommen, A.1    Grigg, J.2
  • 40
    • 0031110139 scopus 로고    scopus 로고
    • Urinary leukotriene E4 and 11-dehydrothromboxane B2 in patients with aspirin-sensitive asthma
    • Oosaki R., Mizushima Y., Mita H., Shida T., Akiyama K., and Kobayashi M. Urinary leukotriene E4 and 11-dehydrothromboxane B2 in patients with aspirin-sensitive asthma. Allergy 52 4 (1997) 470-473
    • (1997) Allergy , vol.52 , Issue.4 , pp. 470-473
    • Oosaki, R.1    Mizushima, Y.2    Mita, H.3    Shida, T.4    Akiyama, K.5    Kobayashi, M.6
  • 41
    • 32444440309 scopus 로고    scopus 로고
    • Influence of leukotriene pathway polymorphisms on response to montelukast in asthma
    • Lima J.J., Zhang S., Grant A., et al. Influence of leukotriene pathway polymorphisms on response to montelukast in asthma. Am. J. Respir. Crit. Care Med. 173 4 (2006) 379-385
    • (2006) Am. J. Respir. Crit. Care Med. , vol.173 , Issue.4 , pp. 379-385
    • Lima, J.J.1    Zhang, S.2    Grant, A.3
  • 42
    • 34247561179 scopus 로고    scopus 로고
    • Pharmacogenetics of the 5-lipoxygenase biosynthetic pathway and variable clinical response to montelukast
    • Klotsman M., York T.P., Pillai S.G., et al. Pharmacogenetics of the 5-lipoxygenase biosynthetic pathway and variable clinical response to montelukast. Pharmacogenet. Genomics 17 3 (2007) 189-196
    • (2007) Pharmacogenet. Genomics , vol.17 , Issue.3 , pp. 189-196
    • Klotsman, M.1    York, T.P.2    Pillai, S.G.3
  • 43
    • 0036017360 scopus 로고    scopus 로고
    • Leukotriene C4 synthase promoter polymorphism in Japanese patients with aspirin-induced asthma
    • Kawagishi Y., Mita H., Taniguchi M., et al. Leukotriene C4 synthase promoter polymorphism in Japanese patients with aspirin-induced asthma. J. Allergy Clin. Immunol. 109 6 (2002) 936-942
    • (2002) J. Allergy Clin. Immunol. , vol.109 , Issue.6 , pp. 936-942
    • Kawagishi, Y.1    Mita, H.2    Taniguchi, M.3
  • 44
    • 0033941793 scopus 로고    scopus 로고
    • 5′ flanking region polymorphism of the gene encoding leukotriene C4 synthase does not correlate with the aspirin-intolerant asthma phenotype in the United States
    • Van Sambeek R., Stevenson D.D., Baldasaro M., et al. 5′ flanking region polymorphism of the gene encoding leukotriene C4 synthase does not correlate with the aspirin-intolerant asthma phenotype in the United States. J. Allergy Clin. Immunol. 106 1 Pt 1 (2000) 72-76
    • (2000) J. Allergy Clin. Immunol. , vol.106 , Issue.1 PART 1 , pp. 72-76
    • Van Sambeek, R.1    Stevenson, D.D.2    Baldasaro, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.