-
1
-
-
0034541434
-
Cytokine modulation of extracellular matrix gene expression: relevance to fibrotic skin diseases
-
Uitto J., and Kouba D. Cytokine modulation of extracellular matrix gene expression: relevance to fibrotic skin diseases. J. Dermatol. Sci. 24 Suppl. 1 (2000) S60-S69
-
(2000)
J. Dermatol. Sci.
, vol.24
, Issue.SUPPL. 1
-
-
Uitto, J.1
Kouba, D.2
-
2
-
-
2442608884
-
TGF-beta and TNF-alpha: antagonistic cytokines controlling type I collagen gene expression
-
Verrecchia F., and Mauviel A. TGF-beta and TNF-alpha: antagonistic cytokines controlling type I collagen gene expression. Cell. Signal. 16 (2004) 873-880
-
(2004)
Cell. Signal.
, vol.16
, pp. 873-880
-
-
Verrecchia, F.1
Mauviel, A.2
-
3
-
-
0034125442
-
Adhesion formation can be reduced by the suppression of transforming growth factor-betal activity
-
Fukui N., Tashiro T., Hiraoka H., et al. Adhesion formation can be reduced by the suppression of transforming growth factor-betal activity. J. Orthop. Res. 18 (2000) 212-219
-
(2000)
J. Orthop. Res.
, vol.18
, pp. 212-219
-
-
Fukui, N.1
Tashiro, T.2
Hiraoka, H.3
-
4
-
-
18144420863
-
Neutralisation of TGF beta or binding of VLA-4 to fibronectin prevents rat tendon adhesion following transection
-
Jørgensen H.G., McLellan S.D., Crossan J.F., et al. Neutralisation of TGF beta or binding of VLA-4 to fibronectin prevents rat tendon adhesion following transection. Cytokine 30 (2005) 195-202
-
(2005)
Cytokine
, vol.30
, pp. 195-202
-
-
Jørgensen, H.G.1
McLellan, S.D.2
Crossan, J.F.3
-
5
-
-
1242306647
-
The role of transforming growth factor beta in lung development and disease
-
Bartram U., and Speer C.P. The role of transforming growth factor beta in lung development and disease. Chest 125 (2004) 754-765
-
(2004)
Chest
, vol.125
, pp. 754-765
-
-
Bartram, U.1
Speer, C.P.2
-
7
-
-
29144486106
-
The complex pattern of SMAD signaling in the cardiovascular system
-
Euler-Taimor G., and Heger J. The complex pattern of SMAD signaling in the cardiovascular system. Cardiovasc. Res. 69 (2006) 15-25
-
(2006)
Cardiovasc. Res.
, vol.69
, pp. 15-25
-
-
Euler-Taimor, G.1
Heger, J.2
-
8
-
-
0041883785
-
Smad3 and PKCdelta mediate TGF-beta1-induced collagen I expression in human mesangial cells
-
Runyan C.E., Schnaper H.W., and Poncelet A.C. Smad3 and PKCdelta mediate TGF-beta1-induced collagen I expression in human mesangial cells. Am. J. Physiol. Renal. Physiol. 285 (2003) F413-F422
-
(2003)
Am. J. Physiol. Renal. Physiol.
, vol.285
-
-
Runyan, C.E.1
Schnaper, H.W.2
Poncelet, A.C.3
-
9
-
-
0023025366
-
Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix
-
Ignotz R.A., and Massagué J. Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. J. Biol. Chem. 261 (1986) 4337-4345
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 4337-4345
-
-
Ignotz, R.A.1
Massagué, J.2
-
10
-
-
0024534977
-
Independent regulation of collagenase, 72-kDa progelatinase, and metalloendoproteinase inhibitor expression in human fibroblasts by transforming growth factor-p
-
Overall C.M., Wraiia J.L., and Sodck J. Independent regulation of collagenase, 72-kDa progelatinase, and metalloendoproteinase inhibitor expression in human fibroblasts by transforming growth factor-p. J. Bid. Chem. 264 (1989) 1860-1869
-
(1989)
J. Bid. Chem.
, vol.264
, pp. 1860-1869
-
-
Overall, C.M.1
Wraiia, J.L.2
Sodck, J.3
-
11
-
-
0032763469
-
Specificity, diversity, and regulation in TGF-beta superfamily signaling
-
Piek E., Heldin C.H., and Ten Dijke P. Specificity, diversity, and regulation in TGF-beta superfamily signaling. FASEB. J. 13 (1999) 2105-2124
-
(1999)
FASEB. J.
, vol.13
, pp. 2105-2124
-
-
Piek, E.1
Heldin, C.H.2
Ten Dijke, P.3
-
12
-
-
0031438047
-
TGF-beta signalling from cell membrane to nucleus through SMAD proteins
-
Heldin C.H., Miyazono K., and ten Dijke P. TGF-beta signalling from cell membrane to nucleus through SMAD proteins. Nature 390 (1997) 465-471
-
(1997)
Nature
, vol.390
, pp. 465-471
-
-
Heldin, C.H.1
Miyazono, K.2
ten Dijke, P.3
-
14
-
-
2342488852
-
New insights into TGF-beta-Smad signalling
-
ten Dijke P., and Hill C.S. New insights into TGF-beta-Smad signalling. Trends Biochem. Sci. 29 (2004) 265-273
-
(2004)
Trends Biochem. Sci.
, vol.29
, pp. 265-273
-
-
ten Dijke, P.1
Hill, C.S.2
-
15
-
-
0029011218
-
The MAPK signaling cascade
-
Seger R., and Krebs E.G. The MAPK signaling cascade. FASEB. J. 9 (1995) 726-735
-
(1995)
FASEB. J.
, vol.9
, pp. 726-735
-
-
Seger, R.1
Krebs, E.G.2
-
16
-
-
0032589970
-
TGF-β1 activates MAP kinase in human mesangial cells: a possible role in collagen expression
-
Hayashida T., Poncelet A.-C., Hubchak S.C., et al. TGF-β1 activates MAP kinase in human mesangial cells: a possible role in collagen expression. Kidney Int. 56 (1999) 1710-1720
-
(1999)
Kidney Int.
, vol.56
, pp. 1710-1720
-
-
Hayashida, T.1
Poncelet, A.-C.2
Hubchak, S.C.3
-
17
-
-
34249777244
-
Mechanisms of tissue inhibitor of metalloproteinase 1 augmentation by IL-13 on TGF-beta 1-stimulated primary human fibroblasts
-
Zhou X., Hu H., Huynh M.L., et al. Mechanisms of tissue inhibitor of metalloproteinase 1 augmentation by IL-13 on TGF-beta 1-stimulated primary human fibroblasts. J. Allergy Clin. Immunol. 119 (2007) 1388-1397
-
(2007)
J. Allergy Clin. Immunol.
, vol.119
, pp. 1388-1397
-
-
Zhou, X.1
Hu, H.2
Huynh, M.L.3
-
18
-
-
0041843962
-
Hepatocyte growth factor suppresses renal interstitial myofibroblast activation and intercepts Smad signal transduction
-
Yang J., Dai C., and Liu Y. Hepatocyte growth factor suppresses renal interstitial myofibroblast activation and intercepts Smad signal transduction. Am. J. Pathol. 163 (2003) 21-32
-
(2003)
Am. J. Pathol.
, vol.163
, pp. 21-32
-
-
Yang, J.1
Dai, C.2
Liu, Y.3
-
19
-
-
33751104222
-
CAMP inhibits transforming growth factor-beta-stimulated collagen synthesis via inhibition of extracellular signal-regulated kinase 1/2 and Smad signaling in cardiac fibroblasts
-
Liu X., Sun S.Q., Hassid A., et al. CAMP inhibits transforming growth factor-beta-stimulated collagen synthesis via inhibition of extracellular signal-regulated kinase 1/2 and Smad signaling in cardiac fibroblasts. Mol. Pharmacol. 70 (2006) 1992-2003
-
(2006)
Mol. Pharmacol.
, vol.70
, pp. 1992-2003
-
-
Liu, X.1
Sun, S.Q.2
Hassid, A.3
-
20
-
-
0042704734
-
Cross-talk between ERK MAP kinase and Smad-signaling pathways enhances TGF-beta dependent responses in human mesangial cells
-
Hayashida T., deCaestecker M., and Schnaper H.W. Cross-talk between ERK MAP kinase and Smad-signaling pathways enhances TGF-beta dependent responses in human mesangial cells. FASEB J. 17 (2003) 1576-1578
-
(2003)
FASEB J.
, vol.17
, pp. 1576-1578
-
-
Hayashida, T.1
deCaestecker, M.2
Schnaper, H.W.3
-
21
-
-
63349085785
-
Efficient inhibition of fibroblast proliferation and collagen expression by ERK2 siRNAs
-
Li F., Fan C., Cheng T., et al. Efficient inhibition of fibroblast proliferation and collagen expression by ERK2 siRNAs. Biochem. Biophys. Res. Commun. 382 (2009) 259-263
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.382
, pp. 259-263
-
-
Li, F.1
Fan, C.2
Cheng, T.3
-
22
-
-
37549016809
-
Single and combined silencing of ERK1 and ERK2 reveals their positive contribution to growth signaling depending on their expression levels
-
Lefloch R., Pouysségur J., and Lenormand P. Single and combined silencing of ERK1 and ERK2 reveals their positive contribution to growth signaling depending on their expression levels. Mol. Cell. Biol. 28 (2008) 511-527
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 511-527
-
-
Lefloch, R.1
Pouysségur, J.2
Lenormand, P.3
-
23
-
-
33845904217
-
ERK1 and ERK2 mitogen-activated protein kinases affect Ras-dependent cell signaling differentially
-
Vantaggiato C., Formentini I., Bondanza A., et al. ERK1 and ERK2 mitogen-activated protein kinases affect Ras-dependent cell signaling differentially. J. Biol. 5 (2006) 14
-
(2006)
J. Biol.
, vol.5
, pp. 14
-
-
Vantaggiato, C.1
Formentini, I.2
Bondanza, A.3
-
24
-
-
34247358156
-
ERK2 but not ERK1 plays a key role in hepatocyte replication: an RNAi-mediated ERK2 knockdown approach in wild-type and ERK1 null hepatocytes
-
Frémin C., Ezan F., Boisselier P., et al. ERK2 but not ERK1 plays a key role in hepatocyte replication: an RNAi-mediated ERK2 knockdown approach in wild-type and ERK1 null hepatocytes. Hepatology 45 (2007) 1035-1045
-
(2007)
Hepatology
, vol.45
, pp. 1035-1045
-
-
Frémin, C.1
Ezan, F.2
Boisselier, P.3
-
25
-
-
49049085537
-
Deletion of ERK2 mitogen-activated protein kinase identifies its key roles in cortical neurogenesis and cognitive function
-
Samuels I.S., Karlo J.C., Faruzzi A.N., et al. Deletion of ERK2 mitogen-activated protein kinase identifies its key roles in cortical neurogenesis and cognitive function. J. Neurosci. 28 (2008) 6983-6995
-
(2008)
J. Neurosci.
, vol.28
, pp. 6983-6995
-
-
Samuels, I.S.1
Karlo, J.C.2
Faruzzi, A.N.3
-
26
-
-
0028109801
-
Transforming growth factor beta in tissue fibrosis
-
Border W.A., and Noble N.A. Transforming growth factor beta in tissue fibrosis. N. Engl. J. Med. 331 (1994) 1286-1292
-
(1994)
N. Engl. J. Med.
, vol.331
, pp. 1286-1292
-
-
Border, W.A.1
Noble, N.A.2
-
27
-
-
0028986030
-
Neutralisation of TGF-beta 1 and TGF-beta 2 or exogenous addition of TGF-beta 3 to cutaneous rat wounds reduces scarring
-
Shah M., Foreman D.M., and Ferguson M.W. Neutralisation of TGF-beta 1 and TGF-beta 2 or exogenous addition of TGF-beta 3 to cutaneous rat wounds reduces scarring. J. Cell. Sci. 12 (1995) 985-1002
-
(1995)
J. Cell. Sci.
, vol.12
, pp. 985-1002
-
-
Shah, M.1
Foreman, D.M.2
Ferguson, M.W.3
-
28
-
-
0033106484
-
A mechanism of repression of TGFbeta/Smad signaling by oncogenic Ras
-
Kretzschmar M., Doody J., Timokhina I., et al. A mechanism of repression of TGFbeta/Smad signaling by oncogenic Ras. Genes Dev. 13 (1999) 804-816
-
(1999)
Genes Dev.
, vol.13
, pp. 804-816
-
-
Kretzschmar, M.1
Doody, J.2
Timokhina, I.3
-
29
-
-
0030613262
-
Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling
-
Souchelnytskyi S., Tamaki K., Engström U., et al. Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling. J. Biol. Chem. 272 (1997) 28107-28115
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 28107-28115
-
-
Souchelnytskyi, S.1
Tamaki, K.2
Engström, U.3
-
30
-
-
0030613249
-
TbetaRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling
-
Abdollah S., Macías-Silva M., Tsukazaki T., et al. TbetaRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling. J. Biol. Chem. 272 (1997) 27678-27685
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 27678-27685
-
-
Abdollah, S.1
Macías-Silva, M.2
Tsukazaki, T.3
-
31
-
-
0033392210
-
TGF-beta: 20 years and counting
-
Sporn M.B. TGF-beta: 20 years and counting. Microbes Infect. 1 (1999) 1251-1253
-
(1999)
Microbes Infect.
, vol.1
, pp. 1251-1253
-
-
Sporn, M.B.1
-
32
-
-
0027418486
-
Stimulation of human embryonic lung fibroblasts by TGF-beta and PDGF acting in synergism. The role of cell density
-
Stathakos D., Psarras S., and Kletsas D. Stimulation of human embryonic lung fibroblasts by TGF-beta and PDGF acting in synergism. The role of cell density. Cell Biol. Int. 17 (1993) 55-64
-
(1993)
Cell Biol. Int.
, vol.17
, pp. 55-64
-
-
Stathakos, D.1
Psarras, S.2
Kletsas, D.3
-
33
-
-
0025114866
-
TGF-beta induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop
-
Battegay E.J., Raines E.W., Seifert R.A., et al. TGF-beta induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop. Cell 17 (1990) 515-524
-
(1990)
Cell
, vol.17
, pp. 515-524
-
-
Battegay, E.J.1
Raines, E.W.2
Seifert, R.A.3
-
34
-
-
0034644472
-
TGFbeta signaling in growth control, cancer, and heritable disorders
-
Massagué J., Blain S.W., and Lo R.S. TGFbeta signaling in growth control, cancer, and heritable disorders. Cell 103 (2000) 295-309
-
(2000)
Cell
, vol.103
, pp. 295-309
-
-
Massagué, J.1
Blain, S.W.2
Lo, R.S.3
-
35
-
-
0037608715
-
Biphasic role of TGF-beta1 in signal transduction and crosstalk
-
Wenner C.E., and Yan S. Biphasic role of TGF-beta1 in signal transduction and crosstalk. J. Cell. Physiol. 196 (2003) 42-50
-
(2003)
J. Cell. Physiol.
, vol.196
, pp. 42-50
-
-
Wenner, C.E.1
Yan, S.2
-
36
-
-
0030773834
-
Opposing BMP and EGF signaling pathways converge on the TGF-β family mediator Smad1
-
Kretzschmar M., Doody J., and Massague J. Opposing BMP and EGF signaling pathways converge on the TGF-β family mediator Smad1. Nature 389 (1997) 618-622
-
(1997)
Nature
, vol.389
, pp. 618-622
-
-
Kretzschmar, M.1
Doody, J.2
Massague, J.3
-
37
-
-
0033106484
-
A mechanism of repression of TGF-β/ Smad signaling by oncogenic Ras
-
Kretzschmar M., Doody J., Timokhina I., et al. A mechanism of repression of TGF-β/ Smad signaling by oncogenic Ras. Genes Dev. 13 (1999) 804-816
-
(1999)
Genes Dev.
, vol.13
, pp. 804-816
-
-
Kretzschmar, M.1
Doody, J.2
Timokhina, I.3
|